Induction of cell death through alteration of oxidants and antioxidants in lung epithelial cells exposed to high energy protons

Journal of Biological Chemistry

Volumn 285, Issue 32, 2010, Pages 24769-24774

  Baluchamy, Sudhakar ^a   Ravichandran, Prabakaran ^a   Periyakaruppan, Adaikkappan ^b   Ramesh, Vani ^a   Hall, Joseph C ^a   Zhang, Ye ^c   Jejelowo, Olufisayo ^b   Gridley, Daila S ^d   Wu, Honglu ^c   Ramesh, Govindarajan T ^a  

^a NORFOLK STATE UNIVERSITY   (United States)

^b TEXAS SOUTHERN UNIVERSITY   (United States)

^c NASA JOHNSON SPACE CENTER   (United States)

^d LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; CELL DEATH; CELL PROLIFERATION; CHEMICAL MODIFICATION; GENES; HEALTH RISKS; HISTOLOGY; MANNED SPACE FLIGHT; MOLECULAR BIOLOGY; OXIDANTS; OXYGEN; PROTONS; QUANTUM OPTICS; RADIATION; SUGAR (SUCROSE); TOXICITY; TUMORS;

APOPTOSIS; APOPTOTIC PATHWAYS; CASPASE-3; CELL PROLIFERATION AND DEATH; CELLULAR MECHANISMS; CONTROL-CELL; DNA FRAGMENTATION; DOSE-DEPENDENT; DOSE-DEPENDENT MANNER; DOUBLE STRANDS; GLUTATHIONES; HEALTHY TISSUES; HIGH ENERGY PROTON; IN-CELL; LUNG EPITHELIAL CELLS; MOLECULAR PROCESS; OUTER SPACE; POTENTIAL HEALTH; PRIMARY RADIATIONS; RADIATION THERAPY; REACTIVE OXYGEN SPECIES; SUGAR MOIETY; SUPER OXIDE DISMUTASE; TUMOR TISSUES;

PROTON IRRADIATION;

CASPASE 3; CASPASE 8; GLUTATHIONE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; ANTIOXIDANT; OXIDIZING AGENT; PROTON;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DNA FRAGMENTATION; LIPID PEROXIDATION; LUNG ALVEOLUS EPITHELIUM; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTON RADIATION; RAT; ANIMAL; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; EPITHELIUM CELL; LUNG; METABOLISM;

ANIMALS; ANTIOXIDANTS; CASPASE 3; CASPASE 8; CELL DEATH; CELL SURVIVAL; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; GLUTATHIONE; LUNG; OXIDANTS; PROTONS; RATS; REACTIVE OXYGEN SPECIES;

EID: 77955284780     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.138099     Document Type: Article

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