Nociceptive trigeminocervical reflexes in healthy subjects

Clinical Neurophysiology

Volumn 121, Issue 9, 2010, Pages 1563-1568

  Serrao, Mariano ^a,b   Coppola, Gianluca ^c   Di Lorenzo, Cherubino ^a   Di Fabio, Roberto ^a   Padua, Luca ^d   Sandrini, Giorgio ^e   Pierelli, Francesco ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b IRCCS NEUROMED   (Italy)

^c IRCCS FONDAZIONE BIETTI   (Italy)

^d IRCCS FONDAZIONE DON CARLO GNOCCHI   (Italy)

^e C MONDINO NATIONAL NEUROLOGICAL INSTITUTE   (Italy)

Author keywords

Habituation; Pain; Recovery cycle; Stimulus intensity response curve; Trigeminocervical complex

Indexed keywords

ADULT; ARTICLE; ELECTROSTIMULATION; HEADACHE; HUMAN; HUMAN EXPERIMENT; LATENT PERIOD; MALE; NECK MUSCLE; NERVE STIMULATION; NEUROTRANSMISSION; NOCICEPTION; NORMAL HUMAN; PAIN THRESHOLD; PRIORITY JOURNAL; REFLEX; SENSORY NERVE; STIMULUS RESPONSE; TRIGEMINAL NERVE; TRIGEMINOCERVICAL REFLEX;

EID: 77955279839     PISSN: 13882457     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinph.2010.03.031     Document Type: Article

References (23)

1. Abrahams V.C., Kori A.A., Loeb G.E., Richmond F., Rose P.K., Keirstead S.A. Facial input to neck motorneurons: trigemino-cervical reflexes in the conscious and anaesthetised cat. Exp Brain Res 1993, 97:23-30.
2. Alstermark B., Pinter M.J., Sasaki S., Tantisira B. Trigeminal excitation of dorsal neck motoneurones in the cat. Exp Brain Res 1992, 92:183-193.
3. Alstermark B., Pinter M.J., Sasaki S. Descending pathways mediating disynaptic excitation of dorsal neck motoneurones in the cat: brainstem relay. Neurosci Res 1992, 15:42-57.
4. Di Lazzaro V., Quartarone A., Higuchi K., Rothwell J.C. Short-latency trigemino-cervical reflexes in man. Exp Brain Res 1995, 102:474-482.
5. Di Lazzaro V., Restuccia D., Nardone R., Tartaglione T., Quartarone A., Tonali P., et al. Preliminary clinical observations on a new trigeminal reflex: the trigemino-cervical reflex. Neurology 1996, 46:479-485.
6. Ellrich J., Treede R.-D. Characterization of blink reflex interneurons by activation of diffuse noxious inhibitory controls in man. Brain Res 1998, 803:161-168.
7. Ellrich J., Andersen O.K., Treede R.-D., Arendt-Nielsen L. Convergence of nociceptive and non-nociceptive input onto the medullary dorsal horn in man. Neuroreport 1998, 9:3213-3217.
8. Ertekin C., Celebisoy N., Uludag B. Trigemino-cervical reflexes in normal subjects. J Neurol Sci 1996, 143:84-90.
9. Ertekin C., Celebisoy N., Uludag B. Trigeminocervical reflexes elicited by stimulation of the infraorbital nerve: head retraction reflex. J Clin Neurophysiol 2001, 18:378-385.
10. Giffin N.J., Katsarava Z., Pfundstein A., Ellrich J., Kaube H. The effect of multiple stimuli on the modulation of the 'nociceptive' blink reflex. Pain 2004, 108:124-128.
11. Kandel E.R., Schwartz J., Jessell T. Principles of neural science 2003, Elsevier. 4th ed.
12. Kaube H., Katsarava Z., Kaufer T., Diener H.C., Ellrich J. A new method to increase nociception specificity of the human blink reflex. Clin Neurophysiol 2000, 111:413-416.
13. Leandri M., Gottlieb A., Cruccu G. Head extensor reflex evoked by trigeminal stimulation in humans. Clin Neurophysiol 2001, 112:1828-1832.
14. Milanov I., Bogdanova D., Ishpekova B. The trigemino-cervical reflex in normal subjects. Funct Neurol 2001, 16:129-134.
15. Rossi B., Pasca S.L., Sartucci F., Siciliano G., Murri L. Trigemino-cervical reflex in pathology of the brainstem and of the first cervical cord segments. Electromyogr Clin Neurophysiol 1989, 29:67-71.
16. Sartucci F., Rossi A., Rossi B. Trigemino cervical reflex in man. Electromyogr Clin Neurophysiol 1986, 26:123-129.
17. Schmid S., Simons N.S., Schnitzler H.U. Cellular mechanisms of the trigeminally evoked startle response. Eur J Neurosci 2003, 17:1438-1444.
18. Serrao M., Rossi P., Parisi L., Perrotta A., Bartolo M., Cardinali P., et al. Trigemino-cervical-spinal reflexes in humans. Clin Neurophysiol 2003, 114:1697-1703.
19. Sessle B.J., Hu J.W., Amano N., Zhong G. Convergence of cutaneous, tooth pulp, visceral, neck and muscle afferents onto nociceptive and non-nociceptive neurones in trigeminal subnucleus caudalis (medullary dorsal horn) and its implications for referred pain. Pain 1986, 27:219-235.
20. Sumino R., Nozaki S. Trigemino-neck reflex: its peripheral and central organization. Pain in the trigeminal region 1977, 369-374. Elsevier North-Holland Biomedical Press, Amsterdam. D.J. Anderson, B. Matthews (Eds.).
21. Sumino R., Nozaki S., Katoh M. Trigemino-neck reflex. Oro-facial sensory and motor functions 1981, 81-88. Quintessence, Tokyo. Y. Kawamura, R. Dubner (Eds.).
22. Takakusaki K., Kohyama J., Matsuyama K., Mori S. Medullary reticulospinal tract mediating the generalized motor inhibition in cats: parallel inhibitory mechanisms acting on motoneurons and on interneuronal transmission in reflex pathways. Neuroscience 2001, 103:511-527.
23. Thompson R.F., Spencer W.A. Habituation: a model phenomenon for the study of neuronal substrates of behavior. Psychol Rev 1966, 73:16-43.