Leishmania major: In vitro and in vivo anti-leishmanial effect of cantharidin

Experimental Parasitology

Volumn 126, Issue 2, 2010, Pages 126-129

  Ghaffarifar, Fatemeh ^a  

^a TARBIAT MODARES UNIVERSITY   (Iran)

Author keywords

Cantharidin; Inflammatory blister technique; Leishmaniasis; Topical treatment

Indexed keywords

CANTHARIDIN;

AMASTIGOTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIPROTOZOAL ACTIVITY; ARTICLE; BAGG ALBINO MOUSE; BLISTER; CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; FEMALE; GROWTH INHIBITION; IC 50; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LEISHMANIA MAJOR; MACROPHAGE; MOUSE; NONHUMAN; PARASITE VIABILITY; PRIORITY JOURNAL; PROMASTIGOTE; SKIN LEISHMANIASIS;

ADMINISTRATION, TOPICAL; ANIMALS; CANTHARIDIN; ENZYME INHIBITORS; FEMALE; IRRITANTS; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED BALB C; OINTMENTS; PROTEIN PHOSPHATASE 1; PROTEIN PHOSPHATASE 2;

LEISHMANIA MAJOR; MELOIDAE; MUS;

EID: 77955278160     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2010.04.004     Document Type: Article

References (18)

1. Bodley A.L., McGarry M.W., Shapiro T.A. Drug cytotoxicity assay for African trypanosomes and Leishmania species. Journal of Infectious Diseases 1995, 172:1157-1159.
2. Callahan H.L., Kelley C., Pereira T., Grogl M. Microtubule inhibitors: structure-activity analyses suggest rational models to identify potentially active compounds. Antimicrobial Agents and Chemotherapy 1996, 40:947-952.
3. Carrel J.E., McCairel M.H., Slagle A.J., Doom J.P., Brill J., McCormick J.P. Cantharidin production in a blister beetle. Experientia 1993, 49:171-174.
4. Cathcart S. Parental satisfaction, efficacy, and adverse events in 54 patients treated with cantharidin for molluscum contagiosum infection. Clinical Pediatrics 2009, 48:161-165.
5. Chang K.P. Human cutaneous lieshmania in a mouse macrophage line: propagation and isolation of intracellular parasites. Science 1980, 209:1240-1242.
6. Day R.M., Harbord M., Forbes A., Segal A.W. Cantharidin blisters: a technique for investigating leukocyte trafficking and cytokine production at sites of inflammation in humans. Journal of Immunological Methods 2001, 257:213-220.
7. Dettner K. Inter and intraspecific transfer of toxic insect compound cantharidin. Vertical Food Web Interactions 1997, 115-145. Springer, Berlin. K. Dettner, G. Bauer, W. Völkl (Eds.).
8. Dettner K., Schramm S., Seidl V., Klemm K., Gäde G., Fietz O., Boland W. Occurance of terpene anhydride palasonin and palasoninimide in blister beetle Hycleus lunata (Coleoptera: Meloidae). Biochemical Systematics and Ecology 2003, 31:203-205.
9. Ghaffarifar F., Jorjani O., Mirshams M., Miranbeigi M.H., Hosseini Z. Photodynamic therapy as a new method for the treatment of cutaneous leishmaniasis. Eastern Mediterranean Health Journal 2006, 12:902-908.
10. Graziano M.J., Pessah I.N., Matsuzawa M., Casida J.E. Partial characterization of specific cantharidin binding sites in mouse tissues. Molecular Pharmacology 1988, 33:706-712.
11. 3H]endothall thioanhydride binding site: inhibitor specificity of cantharidin and ATP analogues. Biochemical Pharmacology 1993, 46:1435-1443.
12. Maglio D., Charles H., Nightingale C., David P. Production and resolution of cantharidin-induced inflammatory blisters. International Journal of Antimicrobial Agents 2003, 22:77-80.
13. Moed L., Shwayder T.A., Chang M.W. Cantharidin revisited a blistering defense of an ancient medicine. Archive of Dermatology 2001, 137:1357-1360.
14. Nikbakhtzadeh M.R., Tirgari S. Cantharidin component of Iranian blister beetles (Col: Meloidae) and their differences between Iranian and exotic species. Iranian Journal of Public Health 2002, 31:113-117.
15. Pierard F.C., Pierard G.E. Cantharidin-induced acantholysis. American Journal of Dermatopathology 1988, 10:419-423.
16. Rauh R., Kahl S., Boechzelt H., Bauer R., Kaina B., Efferth T. Molecular biology of cantharidin in cancer cells. Chinese Medicine 2007, 2:8-16.
17. Wang C.C., Wu C.H., Hsieh K.J., Yen K.Y., Yang L.L. Cytotoxic effects of cantharidin on the growth of normal and carcinoma cells. Toxicology 2000, 147:77-87.
18. Yell J.A., Burge S.M., Dean D. Cantharidin induced acantholysis in Darier's disease: does acantholysis initiate dyskeratosis?. British Journal of Dermatology 2006, 131:40-47.