Subcellular localization and topology of porcine reproductive and respiratory syndrome virus E protein

Virus Research

Volumn 152, Issue 1-2, 2010, Pages 104-114

  Yu, Maorong ^a,b   Liu, Xiaoling ^a,b   Sun, Lei ^a,b   Chen, Caiwei ^a,b   Ma, Guangpeng ^c   Kitamura, Yoshihiro ^a   Gao, George F ^a,b   Liu, Wenjun ^a,b  

^a INSTITUTE OF MICROBIOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c CHINA RURAL TECHNOLOGY DEVELOPMENT CENTER   (China)

Author keywords

Envelope protein E; Membrane association; PRRS virus; Subcellular localization; Topology

Indexed keywords

MEMBRANE PROTEIN; PHOSPHOLIPID; VIRUS PROTEIN; SIGNAL PEPTIDE;

AMINO TERMINAL SEQUENCE; ARTERIVIRUS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GOLGI COMPLEX; HYDROPHILICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SWINE; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; GENETICS; HAPLORHINI; METABOLISM; MOLECULAR GENETICS; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME; PROTEIN MOTIF; PROTEIN TRANSPORT; SEQUENCE ALIGNMENT; VIROLOGY;

PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CELL LINE; ENDOPLASMIC RETICULUM; GOLGI APPARATUS; HAPLORHINI; MOLECULAR SEQUENCE DATA; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; PROTEIN SORTING SIGNALS; PROTEIN TRANSPORT; SEQUENCE ALIGNMENT; SWINE; VIRAL NONSTRUCTURAL PROTEINS;

EID: 77955273848     PISSN: 01681702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virusres.2010.06.012     Document Type: Article

References (20)

1. Cavanaugh D. Nidovirales: a new order comprising Coronaviridae and Arteriviridae. Arch. Virol. 1997, 142(3):629-633.
2. Costers S., Delputte P.L., Nauwynck H.J. Porcine reproductive and respiratory syndrome virus-infected alveolar macrophages contain no detectable levels of viral proteins in their plasma membrane and are protected against antibody-dependent, complement-mediated cell lysis. J. Gen. Virol. 2006, 87(8):2341-2351.
3. de Jong A.S., Wessels E., Dijkman H.B.P.M., Galama J.M.D., Melchers W.J.G., Willems P.H.G.M., Kuppeveld F.J.M.V. Determinants for membrane association and permeabilization of the coxsackievirus 2B protein and the identification of the Golgi complex as the target organelle. J. Biol. Chem. 2003, 278(2):1012-1021.
4. Du Y., Zuckermann F.A., Yoo D. Myristoylation of the small envelope protein of porcine reproductive and respiratory syndrome virus is non-essential for virus infectivity but promotes its growth. Virus Res. 2010, 147(2):294-299.
5. Halbur P.G., Paul P.S., Frey M.L., Landgraf J., Eernisse K., Meng X.J., Lum M.A., Andrews J.J., Rathje J.A. Comparison of the pathogenicity of two US porcine reproductive and respiratory syndrome virus isolates with that of the Lelystad virus. Vet. Pathol. 1995, 32(6):648-660.
6. Lange Y. Disposition of intracellular cholesterol in human fibroblasts. J. Lipid Res. 1991, 32(2):329-339.
7. Lee C., Yoo D. The small envelope protein of porcine reproductive and respiratory syndrome virus possesses ion channel protein-like properties. Virology 2006, 355(1):30-43.
8. Lorenz H., Hailey D.W., Lippincott-Schwartz J. Fluorescence protease protection of GFP chimeras to reveal protein topology and subcellular localization. Nat. Methods 2006, 3(3):205-210.
9. Magnusson P., Hyllseth B., Marusyk H. Morphological studies on equine arteritis virus. Arch. Gesamte Virusforsch. 1970, 30(2):105-112.
10. Meng X.-J., Paul P.S., Halbur P.G., Lum M.A. Phylogenetic analyses of the putative M (ORF 6) and N (ORF 7) genes of porcine reproductive and respiratory syndrome virus (PRRSV): implication for the existence of two genotypes of PRRSV in the U.S.A. and Europe. Arch. Virol. 1995, 140(4):745-755.
11. Meulenberg J.J.M., Besten A.P.-D., Kluyver E.P.D., Moormann R.J.M., Schaaper W.M.M., Wensvoort G. Characterization of proteins encoded by ORFs 2 to 7 of Lelystad virus. Virology 1995, 206(1):155-163.
12. Nakai K., Horton P. PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization. Trends Biochem. Sci. 1999, 24(1):34-35.
13. Nelsen C.J., Murtaugh M.P., Faaberg K.S. Porcine reproductive and respiratory syndrome virus comparison: divergent evolution on two continents. J. Virol. 1999, 73(1):270-280.
14. Snijder E.J., Meulenberg J.J.M. The molecular biology of arteriviruses. J. Gen. Virol. 1998, 79(Pt 5):961-979.
15. Snijder E.J., Tol H.V., Pedersen K.W., Raamsman M.J.B., Vries A.A.F.D. Identification of a novel structural protein of arteriviruses. J. Virol. 1999, 73(8):6335-6345.
16. Stueckemann J.A., Holth M., Swart W.J., Kowalchyk K., Smith M.S., Wolstenholme A.J., Cafruny W.A., Plagemann P.G.W. Replication of Lactate Dehydrogenase-elevating Virus in Macrophages: 2 Mechanism of Persistent Infection in Mice and Cell Culture. J. Gen. Virol. 1982, 59(2):263-272.
17. Thaa B., Kabatek A., Zevenhoven-Dobbe J.C., Snijder E.J., Herrmann A., Veit M. Myristoylation of the arterivirus E protein: the fatty acid modification is not essential for membrane association but contributes significantly to virus infectivity. J. Gen. Virol. 2009, 90(Pt 11):2704-2712.
18. Wood O., Tauraso N., Liebhaber H. Electron Microscopic Study of Tissue Cultures Infected with Simian Haemorrhagic Fever Virus. J. Gen. Virol. 1970, 7(2):129-136.
19. Wissink E.H.J., Kroese M.V., Wijk H.A.R.V., Rijsewijk F.A.M., Meulenberg J.J.M., Rottier P.J.M. Envelope protein requirements for the assembly of infectious virions of porcine reproductive and respiratory syndrome virus. J. Virol. 2005, 79(19):12495-12506.
20. Wu W.-H., Fang Y., Farwell R., Steffen-Bien M., Rowland R.R.R., Christopher-Hennings J., Nelson E.A. A 10-kDa structural protein of porcine reproductive and respiratory syndrome virus encoded by ORF2b. Virology 2001, 287(1):183-191.