Age-related hemodynamic changes during vasovagal syncope

Autonomic Neuroscience: Basic and Clinical

Volumn 156, Issue 1-2, 2010, Pages 131-137

  Folino, Antonio Franco ^a   Migliore, Federico ^a   Marinelli, Alessio ^a   Iliceto, Sabino ^a   Buja, Gianfranco ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Aging; Blood pressure; Heart rate; Hemodynamic; Syncope; Tilt table testing

Indexed keywords

ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; NITRATE;

ADOLESCENT; ADULT; AGED; ARTICLE; BLOOD PRESSURE MONITORING; BRADYCARDIA; CHILD; CONTROLLED STUDY; FEMALE; GROUPS BY AGE; HEART RATE; HEART STROKE VOLUME; HEMODYNAMICS; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; ORTHOSTATIC HYPOTENSION; PRIORITY JOURNAL; PROVOCATION TEST; SCHOOL CHILD; STANDING; SYMPATHETIC INNERVATION; SYNCOPE; SYSTOLIC BLOOD PRESSURE; TILT TABLE TEST; VAGUS NERVE STIMULATION; VASCULAR RESISTANCE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGING; BLOOD PRESSURE; CHILD; FEMALE; HEART RATE; HEMODYNAMICS; HUMANS; MALE; MIDDLE AGED; STROKE VOLUME; SYNCOPE, VASOVAGAL; YOUNG ADULT;

EID: 77955273415     PISSN: 15660702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autneu.2010.04.009     Document Type: Article

References (38)

1. Abboud F.M. Ventricular syncope. Is the heart a sensory organ?. New Engl. J. Med. 1989, 320:390-392.
2. Abi-Samra F., Maloney J.D., Fouad-Tarazi F.M., Castle L.W. The usefulness of head-up tilt testing and hemodynamic investigations in the workup of syncope of unknown origin. Pacing Clin. Electrophysiol. 1988, 11:1202-1214.
3. Alboni P., Brignole M., Menozzi C., et al. Clinical spectrum of neurally mediated reflex syncopes. Europace 2004, 6:55-62.
4. Brignole M., Menozzi C., Del Rosso A., et al. New classification of haemodynamics of vasovagal syncope: beyond the VASIS classification. Europace 2000, 2:66-76.
5. Brignole M., Alboni P., Benditt D., et al. Task Force on Syncope, European Society of Cardiology. Guidelines on management (diagnosis and treatment) of syncope. Eur. Heart J. 2001, 22:1256-1306.
6. Ermis C., Samniah N., Sakaguchi S., et al. Comparison of catecholamine response during tilt-table-induced vasovagal syncope in patients <35 to those >65years of age. Am. J. Cardiol. 2004, 93:225-227.
7. Esler M., Jackman G., Bobik A. Determination of norepinephrine apparent release rate and clearance in humans. Life Sci. 1979, 25:1461-1470.
8. Esler M.D., Thompson J.M., Kaye D.M., et al. Effects of aging on the responsiveness of the human cardiac sympathetic nerves to stressors. Circulation 1995, 91:351-358.
9. Esler M.D., Kaye D.M., Thompson J.M., et al. Effects of aging on epinephrine secretion, and on regional release of epinephrine from the human heart. J. Clin. Endocrinol. Metab. 1995, 80:435-442.
10. Folino A.F. Cerebral autoregulation and syncope. Prog. Cardiovasc. Dis. 2007, 50:49-80.
11. Jones P.P., Christou D.D., Jordan J., Seals D.R. Baroreflex buffering is reduced with age in healthy men. Circulation 2003, 107:1770-1774.
12. Julu P.O., Cooper V.L., Hansen S., Hainsworth R. Cardiovascular regulation in the period preceding vasovagal syncope in conscious humans. J. Physiol. (Lond.) 2003, 549:299-311.
13. Kapoor W., Snustad D., Peterson J., Wieland H.S., Cha R., Karpf M. Syncope in the elderly. Am. J. Med. 1986, 80:419-428.
14. Kapoor W., Snustad D., Peterson J., Wieland H.S., Cha R., Karpf M. Syncope in the elderly. Am. J. Med. 1986, 80:419-428.
15. Kenny R.A., Lyon C.C., Bayliss J., Lightman S.L., Sutton R. Reduced plasma renin activity in elderly subjects in response to vasovagal hypotension and head-up tilt. Age Ageing 1987, 16:171-177.
16. Kurbaan A.S., Bowker T.J., Wijesekera N., et al. Age and hemodynamic responses to tilt testing in those with syncope of unknown origin. J. Am. Coll. Cardiol. 2003, 41:1004-1007.
17. Kurbaan A.S., Bowker T.J., Wijesekera N., et al. Age and hemodynamic responses to tilt testing in those with syncope of unknown origin. J. Am. Coll. Cardiol. 2003, 41:1004-1007.
18. Lipsitz L.A., Mietus J., Moody G.B., Goldberger A.L. Spectral characteristics of heart rate variability before and during postural tilt. Relations to aging and risk of syncope. Circulation 1990, 81:1803-1810.
19. Madrid A.H., Ortega J., Rebollo J.G., et al. Lack of efficacy of atenolol for the prevention of neurally-mediated syncope in highly symptomatic population: a prospective double-blind, randomized and placebo-controlled study. J. Am. Coll. Cardiol. 2001, 37:554-557.
20. McIntosh S., Da Costa D., Kenny R.A. Outcome of an integrated approach to the investigation of dizziness, falls and syncope in elderly patients referred to a 'syncope' clinic. Age Ageing 1993, 22:53-58.
21. Mehlsen J., Nymann Kaijer M., Mehlsen A.-B. Autonomic and electrocardiographic changes in cardioinhibitory syncope. Europace 2008, 10:91-95.
22. Monahan K.D. Effect of aging on baroreflex function in humans. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007, 293:R3-R12.
23. Morillo C.A., Eckberg D.L., Ellenbogen K.A., et al. Vagal and sympathetic mechanisms in patients with orthostatic vasovagal syncope. Circulation 1997, 96:2509-2513.
24. O'Mahony D., Foote C. Prospective evaluation of unexplained syncope, dizziness, and falls among community-dwelling elderly adults. J. Gerontol. A Biol. Sci. Med. Sci. 1998, 53:M435-M440.
25. Olsen H., Lanne T. Reduced venous compliance in lower limbs of aging humans and its importance for capacitance function. Am. J. Physiol. Heart Circ. Physiol. 1998, 275:H878-H886.
26. Rea R.F., Thames M.D. Neural control mechanisms and vasovagal syncope. J. Cardiovasc. Electrophysiol. 1993, 4:587-595.
27. Robertson R.M., Medina E., Shah N., et al. Neurally mediated syncope: pathophysiology and implications for treatment. Am. J. Med. Sci. 1999, 317:102-109.
28. Ruiz G.A., Madoery C., Arnaldo F., Menendez C., Tentori M.C. Frequency-domain analysis of heart rate variability during positive and negative head-up tilt test: importance of age. Pacing Clin. Electrophysiol. 2000, 23:325-332.
29. 123I-Metaiodobenzylguanidine (MIBG) imaging. Circ. J. 2009, 73:310-315.
30. Schroeder C., Bush V.E., Norcliffe L.J., et al. Water drinking acutely improves orthostatic tolerance in healthy subjects. Circulation 2002, 106:2806-2811.
31. Seals D.R., Esler M.D. Human aging and the sympathoadrenal system. J. Physiol. (Lond.) 2000, 528:407-417.
32. Simpson D.M., Wicks R. Spectral analysis of heart rate indicates reduced baroreceptor-related heart rate variability in elderly persons. J. Gerontol. 1988, 43:M21-M24.
33. Sundlof G., Wallin B.G. Human muscle nerve sympathetic activity at rest. Relationship to blood pressure and age. J. Physiol. 1978, 274:621-637.
34. Theopistou A., Gatzoulis K., Economou E., et al. Biochemical changes involved in the mechanism of vasovagal syncope. Am. J. Cardiol. 2001, 88:376-381.
35. Thoren P. Characteristic of left ventricular receptors with nonmedullated vagal afferents. Circ. Res. 1977, 40:415-421.
36. Tsutsui Y., Sagawa S., Yamauchi K., Endo Y., Yamazaki F., Shiraki K. Cardiovascular responses to lower body negative pressure in the elderly: role of reduced leg compliance. Gerontology 2002, 48:133-139.
37. Wesseling K.H., Jansen J.R.C., Settels J.J., et al. Computation of aortic flow from pressure in humans using a nonlinear, three-element model. J. Appl. Physiol. 1993, 74:2566-2573.
38. Ziegler M.G., Lake C.R., Kopin I.J. Plasma noradrenaline increases with age. Nature 1976, 261:333-335.