Second-line treatment in the Malawi antiretroviral programme: high early mortality, but good outcomes in survivors, despite extensive drug resistance at baseline

HIV Medicine

Volumn 11, Issue 8, 2010, Pages 510-518

  Hosseinipour, M C ^a,b   Kumwenda, J J ^c,d   Weigel, R ^e   Brown, L B ^b   Mzinganjira, D ^a   Mhango, B ^c   Eron, J J ^b   Phiri, S ^e   van Oosterhout, J J ^c  

^a UNIVERSITY OF NORTH CAROLINA PROJECT   (Malawi)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c UNIVERSITY OF MALAWI   (Malawi)

^d Johns Hopkins Project   (Malawi)

^e LIGHTHOUSE TRUST   (Malawi)

Author keywords

Antiretroviral therapy; HIV resistance; Malawi; Mortality; Resource limited setting; Second line

Indexed keywords

ABACAVIR; CREATININE; GLUCOSE; HEMOGLOBIN; LACTIC ACID; LAMIVUDINE; LOPINAVIR PLUS RITONAVIR; STAVUDINE; TENOFOVIR; VIRUS RNA; ZIDOVUDINE;

ADULT; ANEMIA; ANTIVIRAL RESISTANCE; ARTICLE; BODY MASS; CD4 LYMPHOCYTE COUNT; CLINICAL TRIAL; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREATININE CLEARANCE; DISEASE SEVERITY; DRUG SUBSTITUTION; DRUG TREATMENT FAILURE; DRUG WITHDRAWAL; FEMALE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; LACTIC ACIDOSIS; MAJOR CLINICAL STUDY; MALAWI; MALE; MORTALITY; NEPHROTOXICITY; NEUTROPENIA; NEUTROPHIL COUNT; PATIENT COMPLIANCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK FACTOR; SIDE EFFECT; TREATMENT OUTCOME; UNSPECIFIED SIDE EFFECT; URBAN AREA; VIRUS LOAD; WORLD HEALTH ORGANIZATION;

ADENINE; ADOLESCENT; ADULT; ANTI-RETROVIRAL AGENTS; BODY MASS INDEX; CD4 LYMPHOCYTE COUNT; DEVELOPING COUNTRIES; DRUG RESISTANCE, VIRAL; DRUG THERAPY, COMBINATION; DRUG TOXICITY; FEMALE; GENOTYPE; HIV INFECTIONS; HIV-1; HUMANS; MALAWI; MALE; MEDICATION ADHERENCE; MIDDLE AGED; NATIONAL HEALTH PROGRAMS; PHOSPHONIC ACIDS; PROSPECTIVE STUDIES; RNA, VIRAL; STATISTICS AS TOPIC; TREATMENT FAILURE; TUBERCULOSIS; URBAN POPULATION; VIRAL LOAD; ZIDOVUDINE;

EID: 77955249946     PISSN: 14642662     EISSN: 14681293     Source Type: Journal    
DOI: 10.1111/j.1468-1293.2010.00825.x     Document Type: Article

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