Fosfomycin suppresses RS-virus-induced Streptococcus pneumoniae and Haemophilus influenzae adhesion to respiratory epithelial cells via the platelet-activating factor receptor

FEMS Microbiology Letters

Volumn 310, Issue 1, 2010, Pages 84-90

  Yokota, Shin Ichi ^a   Okabayashi, Tamaki ^a   Yoto, Yuko ^a   Hori, Tsukasa ^a   Tsutsumi, Hiroyuki ^a   Fujii, Nobuhiro ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

bacterial adhesion; fosfomycin; Haemophilus influenzae; human respiratory syncytial virus; platelet activating factor receptor; Streptococcus pneumoniae

Indexed keywords

FOSFOMYCIN; MESSENGER RNA; PHOSPHORYLCHOLINE; THROMBOCYTE ACTIVATING FACTOR RECEPTOR;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIUM ADHERENCE; CELL SURFACE; CONTROLLED STUDY; DRUG MECHANISM; EPITHELIUM CELL; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; HAEMOPHILUS INFLUENZAE; HUMAN; HUMAN CELL; IMMUNOMODULATION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; RESPIRATORY EPITHELIUM; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STREPTOCOCCUS PNEUMONIAE; VIRAL RESPIRATORY TRACT INFECTION;

ANTI-BACTERIAL AGENTS; BACTERIAL ADHESION; CELL LINE; EPITHELIAL CELLS; FLOW CYTOMETRY; FOSFOMYCIN; GENE EXPRESSION; HAEMOPHILUS INFLUENZAE; HUMANS; MICROSCOPY, FLUORESCENCE; PLATELET MEMBRANE GLYCOPROTEINS; RECEPTORS, G-PROTEIN-COUPLED; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; STREPTOCOCCUS PNEUMONIAE;

BACTERIA (MICROORGANISMS); HAEMOPHILUS INFLUENZAE; HUMAN RESPIRATORY SYNCYTIAL VIRUS; RICE STRIPE VIRUS; STREPTOCOCCUS PNEUMONIAE;

EID: 77955243922     PISSN: 03781097     EISSN: 15746968     Source Type: Journal    
DOI: 10.1111/j.1574-6968.2010.02049.x     Document Type: Article

References (30)

1. Andrade MA, Hoberman A, Glustein J, Paradise JL Wald ER (1998) Acute otitis media in children with bronchiolitis. Pediatrics 101 : 617 619.
2. Assmann G Schriewer H (1985) Choline. Methods in Enzymatic Analysis, Vol. VIII (Bergmeyer H, Bergmeyer J Grassl M, eds), pp. 106 111. Verlag Chemie, Weinheim.
3. Avadhanula V, Rodriguez CA, Devincenzo JP, Wang Y, Webby RJ, Ulett GC Adderson EE (2006) Respiratory viruses augment the adhesion of bacterial pathogens to respiratory epithelium in a viral species- and cell type-dependent manner. J Virol 80 : 1629 1636.
4. Chonmaitree T Heikkinen T (2000) Viruses and acute otitis media. Pediatr Infect Dis J 19 : 1005 1007.
5. Cundell DR, Gerard NP, Gerard C, Idanpaan-Heikkila I Tuomanen EI (1995) Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor. Nature 377 : 435 438.
6. Cundell DR, Gerard C, Idanpaan-Heikkila I, Tuomanen EI Gerard NP (1996) PAf receptor anchors Streptococcus pneumoniae to activated human endothelial cells. Adv Exp Med Biol 416 : 89 94.
7. Goto M, Sugiyama M, Nakajima S Yamashina H (1981) Fosfomycin kinetics after intravenous and oral administration to human volunteers. Antimicrob Agents Ch 20 : 393 397.
8. Hament JM, Kimpen JL, Fleer A Wolfs TF (1999) Respiratory viral infection predisposing for bacterial disease: a concise review. FEMS Immunol Med Mic 26 : 189 195.
9. Hament JM, Aerts PC, Fleer A, Van Dijk H, Harmsen T, Kimpen JL Wolfs TF (2004) Enhanced adherence of Streptococcus pneumoniae to human epithelial cells infected with respiratory syncytial virus. Pediatr Res 55 : 972 978.
10. Honda J, Okubo Y, Kusaba M, Kumagai M, Saruwatari N Oizumi K (1998) Fosfomycin (FOM: 1 R-2S-epoxypropylphosphonic acid) suppress the production of IL-8 from monocytes via the suppression of neutrophil function. Immunopharmacology 39 : 149 155.
11. Ishizaka S, Takeuchi H, Kimoto M, Kanda S Saito S (1998) Fosfomycin, an antibiotic, possessed TGF-β-like immunoregulatory activities. Int J Immunopharmaco 20 : 765 779.
12. Ishizuka S, Yamaya M, Suzuki T, Nakayama K, Kamanaka M, Ida S, Sekizawa K Sasaki H (2001) Acid exposure stimulates the adherence of Streptococcus pneumoniae to cultured human airway epithelial cells: effects on platelet-activating factor receptor expression. Am J Resp Cell Mol 24 : 459 468.
13. Ishizuka S, Yamaya M, Suzuki T, Takahashi H, Ida S, Sasaki T, Inoue D, Sekizawa K, Nishimura H Sasaki H (2003) Effects of rhinovirus infection on the adherence of Streptococcus pneumoniae to cultured human airway epithelial cells. J Infect Dis 188 : 1928 1939.
14. Kim PE, Musher DM, Glezen WP, Rodriguez-Barradas MC, Nahm WK Wright CE (1996) Association of invasive pneumococcal disease with season, atmospheric conditions, air pollution, and the isolation of respiratory viruses. Clin Infect Dis 22 : 100 106.
15. Matsumoto T, Tateda K, Miyazaki S, Furuya N, Ohno A, Ishii Y, Hirakata Y Yamaguchi K (1997) Immunomodulating effect of fosfomycin on gut-derived sepsis caused by Pseudomonas aeruginosa in mice. Antimicrob Agents Ch 41 : 308 313.
16. Matsumoto T, Tateda K, Miyazaki S, Furuya N, Ohno A, Ishii Y, Hirakata Y Yamaguchi K (1999) Fosfomycin alters lipopolysaccharide-induced inflammatory cytokine production in mice. Antimicrob Agents Ch 43 : 697 698.
17. Morikawa K, Oseko F Morikawa S (1993a) Immunomodulatory effect of fosfomycin on human B-lymphocyte function. Antimicrob Agents Ch 37 : 270 275. (Pubitemid 23046567)
18. Morikawa K, Oseko F, Morikawa S Sawada M (1993b) Immunosuppressive activity of fosfomycin on human T-lymphocyte function in vitro. Antimicrob Agents Ch 37 : 2684 2687. (Pubitemid 23357868)
19. Morikawa K, Watabe H, Araake M Morikawa S (1996) Modulatory effect of antibiotics on cytokine production by human monocytes in vitro. Antimicrob Agents Ch 40 : 1366 1370.
20. Morikawa K, Nonaka M, Torii I Morikawa S (2003) Modulatory effect of fosfomycin on acute inflammation in the rat air pouch model. Int J Antimicrob Ag 21 : 334 339.
21. Mutoh H, Ishii S, Izumi T, Kato S Shimizu T (1994) Platelet-activating factor (PAF) positively auto-regulates the expression of human PAF receptor transcript 1 (leukocyte-type) through NF-κ B. Biochem Bioph Res Co 205 : 1137 1142.
22. Ohkoshi Y, Yokota S, Sato K, Hayashi T, Matsuda K, Kuwahara O, Akizawa H Fujii N (2008) Antibiotic susceptibility of Haemophilus influenzae strains isolated from various clinical sources in Hokkaido Prefecture, Japan. J Infect Chemother 14 : 93 98.
23. Okabayashi T, Kariwa H, Yokota S, Iki S, Indoh T, Yokosawa N, Takashima I, Tsutsumi H Fujii N (2006) Cytokine regulation in SARS coronavirus infection compared to other respiratory virus infections. J Med Virol 78 : 417 424.
24. Okabayashi T, Yokota S, Yoto Y, Tsutsumi H Fujii N (2009) Fosfomycin suppresses chemokine induction in airway epithelial cells infected with respiratory syncytial virus. Clin Vaccine Immunol 16 : 859 865.
25. Popovic M, Steinort D, Pillai S Joukhadar C (2009) Fosfomycin: an old, new friend? Eur J Clin Microbiol 29 : 127 142.
26. Shimizu T Mutoh H (1997) Structure and regulation of platelet activating factor receptor gene. Adv Exp Med Biol 407 : 197 204.
27. Swords WE, Buscher BA, Ver Steeg Ii K, Preston A, Nichols WA, Weiser JN, Gibson BW Apicella MA (2000) Non-typeable Haemophilus influenzae adhere to and invade human bronchial epithelial cells via an interaction of lipooligosaccharide with the PAF receptor. Mol Microbiol 37 : 13 27.
28. Yokota S, Sato K, Yoshida S et al 2004) Macrolide-resistant Streptococcus pneumoniae clinical isolates that occur in Hokkaido prefecture, Japan. J Infect Chemother 10 : 284 287.
29. Yoneshima Y, Ichiyama T, Ayukawa H, Matsubara T Furukawa S (2003) Fosfomycin inhibits NF-κB activation in U-937 and Jurkat cells. Int J Antimicrob Ag 21 : 589 592.
30. Yother J, Leopold K, White J Fischer W (1998) Generation and properties of a Streptococcus pneumoniae mutant which does not require choline or analogs for growth. J Bacteriol 180 : 2093 2101.