Nitric oxide production and its contribution to hepatocyte proliferation in normal juvenile rats

Journal of Veterinary Medical Science

Volumn 72, Issue 7, 2010, Pages 861-867

  Inukai, Naoto ^a   Uchida, Mayuko ^a   Miyazaki, Yoko ^a   Suzuki, Takehito ^a   Yoshikawa, Hiroshi ^a   Tanaka, Kazuaki ^a   Morita, Hidetoshi ^a   Takizawa, Tatsuya ^a  

^a AZABU UNIVERSITY   (Japan)

Author keywords

Electron paramagnetic resonance (EPR) spectroscopy; Hepatocyte; Nitric oxide

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; N(G) NITROARGININE METHYL ESTER; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; PRIMER DNA;

AGING; ANIMAL; ARTICLE; CELL DIVISION; CYTOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; LIVER CELL; METABOLISM; PHYSIOLOGY; RAT; REFERENCE VALUE;

AGING; ANIMALS; CELL DIVISION; DNA PRIMERS; HEPATOCYTES; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE II; RATS; REFERENCE VALUES; RNA, MESSENGER;

RATTUS;

EID: 77955240419     PISSN: 09167250     EISSN: 13477439     Source Type: Journal    
DOI: 10.1292/jvms.09-0551     Document Type: Article

References (28)

1. Dimmeler, S., Fleming, I., Fisslthaler, B., Hermann, C., Busse, R. and Zeiher, A. M. 1999. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 399: 601-605.
2. 2+ signaling in neonatal and adult rat hepatocytes doublets. J. Hepatol. 28: 221-230.
3. Fausto, N. and Campbell, J. S. 2003. The role of hepatocytes and oval cells in liver regeneration and repopulation. Mech. Dev. 120: 117-130.
4. Fausto, N., Campbell, J. S. and Riehle, K. J. 2006. Liver regeneration. Hepatology 43: S45-S53.
5. Fleming, I., Fisslthaler, B., Dimmeler, S., Kemp, B. E. and Busse, R. 2001. Phosphorylation of Thr (495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity. Circ. Res. 88: E68-E75.
6. García-Trevijano, E. R., Martínez-Chantar, M. L., Latasa. M. U., Mato, J. M. and Avila, M. A. 2002. NO sensitizes rat hepatocytes to proliferation by modifying s-adenosylmethionine levels. Gastroenterology 122: 1355-1363.
7. Greengard, O. 1970. Enzymic differentiation in mammalian tissues. Essays Biochem. 7: 159-205.
8. López-Farré, A., Rodríguez-Feo, J. A., Sánchez, de, Miguel, L., Rico, L. and Casado, S. 1998. Role of nitric oxide in the control of apoptosis in the microvasculature. Int. J. Biochem. Cell. Biol. 30: 1095-1106.
9. Makondo, K., Kimura, K., Kitamura, N., Kitamura, T., Yamaji, D., Jung, B. D. and Saito, M. 2003. Hepatocyte growth factor activates endothelial nitric oxide synthase by Ca (2+)- and phosphoinositide 3-kinase/Akt-dependent phosphorylation in aortic endothelial cells. Biochem. J. 374: 63-69.
10. Mittal, M. K., Gupta, T. K., Lee, F. Y., Sieber, C. C. and Groszmann, R. J. 1994. Nitric oxide modulates hepatic vascular tone in normal rat liver. Am. J. Physiol. 267: G416-G422.
11. Moncada, S., Palmer, R. M. J. and Higgs, E. A. 1991. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol. Rev. 43: 109-142.
12. Nagao, M., Nakamura, T. and Ichihara, A. 1986. Developmental control of gene expression of tryptophan 2,3-dioxygenase in neonatal rat liver. Biochim. Biophys. Acta 867: 179-186.
13. Nowicki, M. J., Shi, D., Cai, Z., Bishop, P. R. and May, W. L. 2003. Developmental expression of endothelial nitric oxide synthase (eNOS) in the rat liver. Pediatr. Res. 54: 732-738.
14. Obolenskaya, M. Y., Vanin, A. F., Mordvintcev, P. I., Mülsch, A. and Decker, K. 1994. EPR evidence of nitric oxide production by the regenerating rat liver. Biochem. Biophys. Res. Commun. 202: 571-576.
15. Palmer, R. M. J., Ferrige, A. G. and Moncada, S. 1987. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327: 524-526.
16. Rai, R. M., Lee, F. Y. J., Rosen, A., Yang, S. Q., Lin, H. Z., Koteish, A., Liew, F. Y., Zaragoza, C., Lowenstein, C. and Diehl, A. M. 1998. Impaired liver regeneration in inducible nitric oxide synthase-deficient mice. Proc. Natl. Acad. Sci. U.S.A. 95: 13829-13834.
17. Repetto, S., Salani, B., Maggi, D. and Cordera, R. 2005. Insulin and IGF-I phosphorylate eNOS in HUVECs by a caveolin-1 dependent mechanism. Biochem. Biophys. Res. Commun. 337: 849-852.
18. Ronco, M. T., Alvarez, M. L., Monti, J. A., Carrillo, M. C., Pisani, G. B., Lugano, M. C. and Carnovale, C. E. 2004. Role of nitric oxide increase on induced programmed cell death during early stages of rat liver regeneration. Biochim. Biophys. Acta 1690: 70-76.
19. Schoen, J. M., Wang, H. H., Minuk, G. Y. and Lautt, W. W. 2001. Shear stress-induced nitric oxide release triggers the liver regeneration cascade. Nitric Oxide 5: 453-464.
20. Schoen-Smith, J. M. and Lautt, W. W. 2005. The role of prostaglandins in triggering the liver regeneration cascade. Nitric Oxide 13: 111-117.
21. Serracino-Inglott, F., Virlos, L. T., Habib, N. A., Williamson, R. C. N. and Mathie, R. T. 2003. Differential nitric oxide synthase expression during hepatic ischemia-reperfusion. Am. J. Surg. 185: 589-595.
22. Shah, V., Haddad, F. G., Garcia-Cardena, G., Frangos, J. A., Mennone, A., Groszmann, R. J. and Sessa, W. C. 1997. Liver sinusoidal endothelial cells are responsible for nitric oxide modulation of resistance in the hepatic sinusoids. J. Clin. Invest. 100: 2923-2930.
23. Suzuki, Y., Fujii, S., Numagami, Y., Tominaga, T., Yoshimoto, T. and Yoshimura, T. 1998. In vivo nitric oxide detection in the septic rat brain by electron paramagnetic resonance. Free Radic. Res. 28: 293-299.
24. Takizawa, T., Yoshikawa, H., Yamada, M. and Morita, H. 2002. Expression of nitric oxide synthase isoforms and detection of nitric oxide in rat placenta. Am. J. Physiol. Cell Physiol. 282: C762-C767.
25. Tuncyurek, P., Yenisey, C., Doger, F. K., Soyder, A., Bicakci, T. and Cevikel, M. H. 2006. Nitric oxide as an independent regulatory factor in regenerating rat liver. Acta Chir. Belg. 106: 581-587.
26. Wang, H. H. and Lautt, W. W. 1998. Evidence of nitric oxide, a flow-dependent factor, being a trigger of liver regeneration in rats. Can. J. Physiol. Pharmacol. 76: 1072-1079.
27. Weglarz, T. C. and Sandgren, E. P. 2000. Timing of hepatocyte entry into DNA synthesis after partial hepatectomy is cell autonomous. Proc. Natl. Acad. Sci. U.S.A. 97: 12595-12600.
28. Yoshimura, T. 1996. Endogenous nitric oxide, its chemical characterization and the high affinity for metal ions and metalloproteins. CVD Grand Round Ser. 3: 1-26.