메뉴 건너뛰기




Volumn 22, Issue 4, 2010, Pages 478-484

The role and importance of brown adipose tissue in energy homeostasis

Author keywords

brown adipose tissue; energy balance; PET8267computed tomography; uncoupling protein 1

Indexed keywords

BONE MORPHOGENETIC PROTEIN; FIBROBLAST GROWTH FACTOR; FLUORODEOXYGLUCOSE F 18; UNCOUPLING PROTEIN 1;

EID: 77955231538     PISSN: 10408703     EISSN: None     Source Type: Journal    
DOI: 10.1097/MOP.0b013e32833a8d6e     Document Type: Review
Times cited : (86)

References (65)
  • 1
    • 44349165737 scopus 로고    scopus 로고
    • High body mass index for age among US children and adolescents, 2003-2006
    • Ogden CL, Carroll MD, Flegal KM. High body mass index for age among US children and adolescents, 2003-2006. JAMA 2008; 299:2401-2405.
    • (2008) JAMA , vol.299 , pp. 2401-2405
    • Ogden, C.L.1    Carroll, M.D.2    Flegal, K.M.3
  • 4
    • 33845864967 scopus 로고    scopus 로고
    • Adipocytes as regulators of energy balance and glucose homeostasis
    • Rosen ED, Spiegelman BM. Adipocytes as regulators of energy balance and glucose homeostasis. Nature 2006; 444:847-853.
    • (2006) Nature , vol.444 , pp. 847-853
    • Rosen, E.D.1    Spiegelman, B.M.2
  • 5
    • 37249062585 scopus 로고    scopus 로고
    • RNAi screens reveal novel metabolic regulators: RIP140, MAP4k4 and the lipid droplet associated fat specific protein (FSP) 27
    • Puri V, Virbasius JV, Guilherme A, Czech MP. RNAi screens reveal novel metabolic regulators: RIP140, MAP4k4 and the lipid droplet associated fat specific protein (FSP) 27. Acta Physiol (Oxf) 2008; 192:103-115.
    • (2008) Acta Physiol (Oxf) , vol.192 , pp. 103-115
    • Puri, V.1    Virbasius, J.V.2    Guilherme, A.3    Czech, M.P.4
  • 6
    • 35348874911 scopus 로고    scopus 로고
    • Developmental origin of fat: Tracking obesity to its source
    • Gesta S, Tseng YH, Kahn CR. Developmental origin of fat: tracking obesity to its source. Cell 2007; 131:242-256.
    • (2007) Cell , vol.131 , pp. 242-256
    • Gesta, S.1    Tseng, Y.H.2    Kahn, C.R.3
  • 7
    • 33847768085 scopus 로고    scopus 로고
    • Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice
    • Almind K, Manieri M, Sivitz WI, et al. Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice. Proc Natl Acad Sci U S A 2007; 104:2366-2371.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 2366-2371
    • Almind, K.1    Manieri, M.2    Sivitz, W.I.3
  • 8
    • 33845977987 scopus 로고    scopus 로고
    • Genetic variability affects the development of brown adipocytes in white fat but not in interscapular brown fat
    • Xue B, Rim JS, Hogan JC, et al. Genetic variability affects the development of brown adipocytes in white fat but not in interscapular brown fat. J Lipid Res 2007; 48:41-51.
    • (2007) J Lipid Res , vol.48 , pp. 41-51
    • Xue, B.1    Rim, J.S.2    Hogan, J.C.3
  • 10
    • 0018348872 scopus 로고
    • Tissue distribution of cold-induced thermogenesis in conscious warm-or cold-acclimated rats reevaluated from changes in tissue blood flow: The dominant role of brown adipose tissue in the replacement of shivering by nonshivering thermogenesis
    • Foster DO, Frydman ML. Tissue distribution of cold-induced thermogenesis in conscious warm-or cold-acclimated rats reevaluated from changes in tissue blood flow: the dominant role of brown adipose tissue in the replacement of shivering by nonshivering thermogenesis. Can J Physiol Pharmacol 1979; 57:257-270.
    • (1979) Can J Physiol Pharmacol , vol.57 , pp. 257-270
    • Foster, D.O.1    Frydman, M.L.2
  • 11
    • 0035462378 scopus 로고    scopus 로고
    • Only UCP1 can mediate adaptive nonshivering thermogenesis in the cold
    • Golozoubova V, Hohtola E, Matthias A, et al. Only UCP1 can mediate adaptive nonshivering thermogenesis in the cold. FASEB J 2001; 15:2048-2050.
    • (2001) FASEB J , vol.15 , pp. 2048-2050
    • Golozoubova, V.1    Hohtola, E.2    Matthias, A.3
  • 12
    • 0030745159 scopus 로고    scopus 로고
    • 3- adrenoceptor agonist
    • DOI 10.1016/S0006-2952(97)00162-7, PII S0006295297001627
    • Ghorbani M, Claus TH, Himms-Hagen J. Hypertrophy of brown adipocytes in brown and white adipose tissues and reversal of diet-induced obesity in rats treated with a beta3-adrenoceptor agonist. Biochem Pharmacol 1997; 54:121-131. (Pubitemid 27353229)
    • (1997) Biochemical Pharmacology , vol.54 , Issue.1 , pp. 121-131
    • Ghorbani, M.1    Claus, T.H.2    Himms-Hagen, J.3
  • 13
    • 0032528169 scopus 로고    scopus 로고
    • Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity
    • Guerra C, Koza RA, Yamashita H, et al. Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity. J Clin Invest 1998; 102:412-420.
    • (1998) J Clin Invest , vol.102 , pp. 412-420
    • Guerra, C.1    Koza, R.A.2    Yamashita, H.3
  • 14
    • 0027731309 scopus 로고
    • Development of obesity in transgenic mice after genetic ablation of brown adipose tissue
    • Lowell BB, Susulic V, Hamann A, et al. Development of obesity in transgenic mice after genetic ablation of brown adipose tissue. Nature 1993; 366:740-742.
    • (1993) Nature , vol.366 , pp. 740-742
    • Lowell, B.B.1    Susulic, V.2    Hamann, A.3
  • 15
    • 0020693920 scopus 로고
    • Luxuskonsumption, diet-induced thermogenesis and brown fat: The case in favour
    • Rothwell NJ, Stock MJ. Luxuskonsumption, diet-induced thermogenesis and brown fat: the case in favour. Clin Sci (Lond) 1983; 64:19-23.
    • (1983) Clin Sci (Lond) , vol.64 , pp. 19-23
    • Rothwell, N.J.1    Stock, M.J.2
  • 16
    • 0013873889 scopus 로고
    • Brown adipose tissue and heat production in the newborn infant
    • Aherne W, Hull D. Brown adipose tissue and heat production in the newborn infant. J Pathol Bacteriol 1966; 91:223-234.
    • (1966) J Pathol Bacteriol , vol.91 , pp. 223-234
    • Aherne, W.1    Hull, D.2
  • 17
    • 0015332110 scopus 로고
    • The distribution of brown adipose tissue in the human
    • Heaton JM. The distribution of brown adipose tissue in the human. J Anat 1972; 112:35-39.
    • (1972) J Anat , vol.112 , pp. 35-39
    • Heaton, J.M.1
  • 18
    • 0017183635 scopus 로고
    • The function of brown adipose tissue in the newborn
    • Hull D. The function of brown adipose tissue in the newborn. Biochem Soc Trans 1976; 4:226-228.
    • (1976) Biochem Soc Trans , vol.4 , pp. 226-228
    • Hull, D.1
  • 19
    • 0015900514 scopus 로고
    • The response of malnourished babies to cold
    • Brooke OG, Harris M, Salvosa CB. The response of malnourished babies to cold. J Physiol 1973; 233:75-91.
    • (1973) J Physiol , vol.233 , pp. 75-91
    • Brooke, O.G.1    Harris, M.2    Salvosa, C.B.3
  • 20
    • 0000452512 scopus 로고
    • Nonshivering thermogenesis and brown adipose tissue in the human new-born infant
    • Dawkins MJ, Scopes JW. Nonshivering thermogenesis and brown adipose tissue in the human new-born infant. Nature 1965; 206:201-202.
    • (1965) Nature , vol.206 , pp. 201-202
    • Dawkins, M.J.1    Scopes, J.W.2
  • 21
    • 0021350359 scopus 로고
    • Ephedrine-induced thermogenesis in man: No role for interscapular brown adipose tissue
    • Astrup A, Bulow J, Christensen NJ, Madsen J. Ephedrine-induced thermogenesis in man: no role for interscapular brown adipose tissue. Clin Sci (Lond) 1984; 66:179-186.
    • (1984) Clin Sci (Lond) , vol.66 , pp. 179-186
    • Astrup, A.1    Bulow, J.2    Christensen, N.J.3    Madsen, J.4
  • 22
    • 34250313542 scopus 로고    scopus 로고
    • Effect of nicotine and ephedrine on the accumulation of 18F-FDG in brown adipose tissue
    • Baba S, Tatsumi M, Ishimori T, et al. Effect of nicotine and ephedrine on the accumulation of 18F-FDG in brown adipose tissue. J Nucl Med 2007; 48:981-986.
    • (2007) J Nucl Med , vol.48 , pp. 981-986
    • Baba, S.1    Tatsumi, M.2    Ishimori, T.3
  • 23
    • 75749098142 scopus 로고    scopus 로고
    • CT Hounsfield units of brown adipose tissue increase with activation: Preclinical and clinical studies
    • Baba S, Jacene HA, Engles JM, et al. CT Hounsfield units of brown adipose tissue increase with activation: preclinical and clinical studies. J Nucl Med 2010; 51:246-250.
    • (2010) J Nucl Med , vol.51 , pp. 246-250
    • Baba, S.1    Jacene, H.A.2    Engles, J.M.3
  • 24
    • 0024691070 scopus 로고
    • Brown adipose tissue in humans
    • Lean ME. Brown adipose tissue in humans. Proc Nutr Soc 1989; 48:243-256.
    • (1989) Proc Nutr Soc , vol.48 , pp. 243-256
    • Lean, M.E.1
  • 25
    • 0017124215 scopus 로고
    • Mitochondrial protein alteration in active brown fat: A sodium dodecyl sulfate-polyacrylamide gel electrophoretic study
    • Ricquier D, Kader JC. Mitochondrial protein alteration in active brown fat: a sodium dodecyl sulfate-polyacrylamide gel electrophoretic study. Biochem Biophys Res Commun 1976; 73:577-583.
    • (1976) Biochem Biophys Res Commun , vol.73 , pp. 577-583
    • Ricquier, D.1    Kader, J.C.2
  • 26
    • 0020359244 scopus 로고
    • Exclusive occurrence of thermogenin antigen in brown adipose tissue
    • Cannon B, Hedin A, Nedergaard J. Exclusive occurrence of thermogenin antigen in brown adipose tissue. FEBS Lett 1982; 150:129-132.
    • (1982) FEBS Lett , vol.150 , pp. 129-132
    • Cannon, B.1    Hedin, A.2    Nedergaard, J.3
  • 27
    • 0020597306 scopus 로고
    • Measurement of rat brown-adiposetissue mitochondrial uncoupling protein by radioimmunoassay: Increased concentration after cold acclimation
    • Lean ME, Branch WJ, James WP, et al. Measurement of rat brown-adiposetissue mitochondrial uncoupling protein by radioimmunoassay: increased concentration after cold acclimation. Biosci Rep 1983; 3:61-71.
    • (1983) Biosci Rep , vol.3 , pp. 61-71
    • Lean, M.E.1    Branch, W.J.2    James, W.P.3
  • 28
    • 0022499231 scopus 로고
    • Brown adipose tissue uncoupling protein content in human infants, children and adults
    • Lean ME, James WP, Jennings G, Trayhurn P. Brown adipose tissue uncoupling protein content in human infants, children and adults. Clin Sci (Lond) 1986; 71:291-297. (Pubitemid 16058739)
    • (1986) Clinical Science , vol.73 , Issue.3 , pp. 291-297
    • Lean, M.E.J.1    James, W.P.T.2    Jennings, G.3    Trayhurn, P.4
  • 29
    • 0024442609 scopus 로고
    • Brown adipose tissue activity in pyrexial cases of cot death
    • Lean ME, Jennings G. Brown adipose tissue activity in pyrexial cases of cot death. J Clin Pathol 1989; 42:1153-1156.
    • (1989) J Clin Pathol , vol.42 , pp. 1153-1156
    • Lean, M.E.1    Jennings, G.2
  • 30
    • 0017805746 scopus 로고
    • Structure of periadrenal brown fat in childhood in both expected and cot deaths
    • Emery JL, Dinsdale F. Structure of periadrenal brown fat in childhood in both expected and cot deaths. Arch Dis Child 1978; 53:154-158.
    • (1978) Arch Dis Child , vol.53 , pp. 154-158
    • Emery, J.L.1    Dinsdale, F.2
  • 31
    • 16844366933 scopus 로고    scopus 로고
    • Guidelines for the cold pressor task as an experimental pain stimulus for use with children
    • von Baeyer CL, Piira T, Chambers CT, et al. Guidelines for the cold pressor task as an experimental pain stimulus for use with children. J Pain 2005; 6:218-227.
    • (2005) J Pain , vol.6 , pp. 218-227
    • Von Baeyer, C.L.1    Piira, T.2    Chambers, C.T.3
  • 32
    • 64349123664 scopus 로고    scopus 로고
    • Functional brown adipose tissue in healthy adults
    • Virtanen KA, Lidell ME, Orava J, et al. Functional brown adipose tissue in healthy adults. N Engl J Med 2009; 360:1518-1525.
    • (2009) N Engl J Med , vol.360 , pp. 1518-1525
    • Virtanen, K.A.1    Lidell, M.E.2    Orava, J.3
  • 33
    • 67650242165 scopus 로고    scopus 로고
    • High incidence of metabolically active brown adipose tissue in healthy adult humans: Effects of cold exposure and adiposity
    • Saito M, Okamatsu-Ogura Y, Matsushita M, et al. High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity. Diabetes 2009; 58:1526-1531.
    • (2009) Diabetes , vol.58 , pp. 1526-1531
    • Saito, M.1    Okamatsu-Ogura, Y.2    Matsushita, M.3
  • 34
    • 33746358537 scopus 로고    scopus 로고
    • Sex, gender, and age: Contributions to laboratory pain responding in children and adolescents
    • Myers CD, Tsao JC, Glover DA, et al. Sex, gender, and age: contributions to laboratory pain responding in children and adolescents. J Pain 2006; 7:556-564.
    • (2006) J Pain , vol.7 , pp. 556-564
    • Myers, C.D.1    Tsao, J.C.2    Glover, D.A.3
  • 35
    • 34848875080 scopus 로고    scopus 로고
    • Effects of preparatory information and distraction on children's cold-pressor pain outcomes: A randomized controlled trial
    • Jaaniste T, Hayes B, von Baeyer CL. Effects of preparatory information and distraction on children's cold-pressor pain outcomes: a randomized controlled trial. Behav Res Ther 2007; 45:2789-2799.
    • (2007) Behav Res Ther , vol.45 , pp. 2789-2799
    • Jaaniste, T.1    Hayes, B.2    Von Baeyer, C.L.3
  • 36
    • 0028136536 scopus 로고
    • DNA polymorphism in the uncoupling protein (UCP) gene and human body fat
    • Oppert JM, Vohl MC, Chagnon M, et al. DNA polymorphism in the uncoupling protein (UCP) gene and human body fat. Int J Obes Relat Metab Disord 1994; 18:526-531.
    • (1994) Int J Obes Relat Metab Disord , vol.18 , pp. 526-531
    • Oppert, J.M.1    Vohl, M.C.2    Chagnon, M.3
  • 37
    • 0033694514 scopus 로고    scopus 로고
    • Studies of the synergistic effect of the Trp/Arg64 polymorphism of the beta3-adrenergic receptor gene and the-3826 A!G variant of the uncoupling protein-1 gene on features of obesity and insulin resistance in a population-based sample of 379 young Danish subjects
    • Urhammer SA, Hansen T, Borch-Johnsen K, Pedersen O. Studies of the synergistic effect of the Trp/Arg64 polymorphism of the beta3-adrenergic receptor gene and the-3826 A!G variant of the uncoupling protein-1 gene on features of obesity and insulin resistance in a population-based sample of 379 young Danish subjects. J Clin Endocrinol Metab 2000; 85:3151-3154.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3151-3154
    • Urhammer, S.A.1    Hansen, T.2    Borch-Johnsen, K.3    Pedersen, O.4
  • 38
    • 0346101854 scopus 로고    scopus 로고
    • The-3826 A!G variant of the uncoupling protein-1 gene diminishes postprandial thermogenesis after a high fat meal in healthy boys
    • Nagai N, Sakane N, Ueno LM, et al. The-3826 A!G variant of the uncoupling protein-1 gene diminishes postprandial thermogenesis after a high fat meal in healthy boys. J Clin Endocrinol Metab 2003; 88:5661-5667.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 5661-5667
    • Nagai, N.1    Sakane, N.2    Ueno, L.M.3
  • 39
    • 0017257444 scopus 로고
    • Energy expenditure in small children of obese and nonobese parents
    • Griffiths M, Payne PR. Energy expenditure in small children of obese and nonobese parents. Nature 1976; 260:698-700.
    • (1976) Nature , vol.260 , pp. 698-700
    • Griffiths, M.1    Payne, P.R.2
  • 40
    • 0019365046 scopus 로고
    • Thermogenesis and obesity
    • James WPT, Trayhurn P. Thermogenesis and obesity. Br Med Bull 1981; 37:43-48.
    • (1981) Br Med Bull , vol.37 , pp. 43-48
    • Wpt, J.1    Trayhurn, P.2
  • 41
    • 34248372084 scopus 로고    scopus 로고
    • Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages
    • Timmons JA, Wennmalm K, Larsson O, et al. Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages. Proc Natl Acad Sci U S A 2007; 104:4401-4406.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 4401-4406
    • Timmons, J.A.1    Wennmalm, K.2    Larsson, O.3
  • 42
    • 50049122271 scopus 로고    scopus 로고
    • PRDM16 controls a brown fat/skeletal muscle switch
    • Seale P, Bjork B, Yang W, et al. PRDM16 controls a brown fat/skeletal muscle switch. Nature 2008; 454:961-967.
    • (2008) Nature , vol.454 , pp. 961-967
    • Seale, P.1    Bjork, B.2    Yang, W.3
  • 43
    • 0028865142 scopus 로고
    • Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity
    • Kopecky J, Clarke G, Enerback S, et al. Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity. J Clin Invest 1995; 96:2914-2923.
    • (1995) J Clin Invest , vol.96 , pp. 2914-2923
    • Kopecky, J.1    Clarke, G.2    Enerback, S.3
  • 44
    • 2942532305 scopus 로고    scopus 로고
    • Nuclear receptor corepressor RIP140 regulates fat accumulation
    • Leonardsson G, Steel JH, Christian M, et al. Nuclear receptor corepressor RIP140 regulates fat accumulation. Proc Natl Acad Sci U S A 2004; 101: 8437-8442.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 8437-8442
    • Leonardsson, G.1    Steel, J.H.2    Christian, M.3
  • 45
    • 0347989317 scopus 로고    scopus 로고
    • Brown adipose tissue: Function and physiological significance
    • Cannon B, Nedergaard J. Brown adipose tissue: function and physiological significance. Physiol Rev 2004; 84:277-359.
    • (2004) Physiol Rev , vol.84 , pp. 277-359
    • Cannon, B.1    Nedergaard, J.2
  • 46
    • 70649109834 scopus 로고    scopus 로고
    • Emerging role of bone morphogenetic proteins in adipogenesis and energy metabolism
    • Schulz TJ, Tseng YH. Emerging role of bone morphogenetic proteins in adipogenesis and energy metabolism. Cytokine Growth Factor Rev 2009; 20:523-531.
    • (2009) Cytokine Growth Factor Rev , vol.20 , pp. 523-531
    • Schulz, T.J.1    Tseng, Y.H.2
  • 47
    • 50049127055 scopus 로고    scopus 로고
    • New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure
    • Tseng YH, Kokkotou E, Schulz TJ, et al. New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure. Nature 2008; 454:1000-1004.
    • (2008) Nature , vol.454 , pp. 1000-1004
    • Tseng, Y.H.1    Kokkotou, E.2    Schulz, T.J.3
  • 48
    • 34247640071 scopus 로고    scopus 로고
    • The incremental value of 18F-FDG PET/CT in paediatric malignancies
    • Bar-Sever Z, Keidar Z, Ben Barak A, et al. The incremental value of 18F-FDG PET/CT in paediatric malignancies. Eur J Nucl Med Mol Imaging 2007; 34:630-637.
    • (2007) Eur J Nucl Med Mol Imaging , vol.34 , pp. 630-637
    • Bar-Sever, Z.1    Keidar, Z.2    Ben Barak, A.3
  • 49
    • 0022478967 scopus 로고
    • Thermogenesis in human brown adipose tissue and skeletal muscle induced by sympathomimetic stimulation
    • Astrup A. Thermogenesis in human brown adipose tissue and skeletal muscle induced by sympathomimetic stimulation. Acta Endocrinol Suppl (Copenh) 1986; 278:1-32.
    • (1986) Acta Endocrinol Suppl (Copenh) , vol.278 , pp. 1-32
    • Astrup, A.1
  • 50
    • 0031661901 scopus 로고    scopus 로고
    • Increase in insulin action and fat oxidation after treatment with CL 316 243, a highly selective beta3-adrenoceptor agonist in humans
    • Weyer C, Tataranni PA, Snitker S, et al. Increase in insulin action and fat oxidation after treatment with CL 316 243, a highly selective beta3-adrenoceptor agonist in humans. Diabetes 1998; 47:1555-1561.
    • (1998) Diabetes , vol.47 , pp. 1555-1561
    • Weyer, C.1    Tataranni, P.A.2    Snitker, S.3
  • 51
    • 0036783754 scopus 로고    scopus 로고
    • Effect of a 28-d treatment with L-796568, a novel beta(3)-adrenergic receptor agonist, on energy expenditure and body composition in obese men
    • Larsen TM, Toubro S, van Baak MA, et al. Effect of a 28-d treatment with L-796568, a novel beta(3)-adrenergic receptor agonist, on energy expenditure and body composition in obese men. Am J Clin Nutr 2002; 76:780-788.
    • (2002) Am J Clin Nutr , vol.76 , pp. 780-788
    • Larsen, T.M.1    Toubro, S.2    Van Baak, M.A.3
  • 52
    • 0022007439 scopus 로고
    • The characterization and energetic potential of brown adipose tissue in man
    • Cunningham S, Leslie P, Hopwood D, et al. The characterization and energetic potential of brown adipose tissue in man. Clin Sci (Lond) 1985; 69:343-348.
    • (1985) Clin Sci (Lond) , vol.69 , pp. 343-348
    • Cunningham, S.1    Leslie, P.2    Hopwood, D.3
  • 54
    • 1642586979 scopus 로고    scopus 로고
    • PET/CT in oncology: Integration into clinical management of lymphoma, melanoma, and gastrointestinal malignancies
    • Schoder H, Larson SM, Yeung HW. PET/CT in oncology: integration into clinical management of lymphoma, melanoma, and gastrointestinal malignancies. J Nucl Med 2004; 45 (Suppl 1):72S-81S.
    • (2004) J Nucl Med , vol.45 , Issue.SUPPL. 1
    • Schoder, H.1    Larson, S.M.2    Yeung, H.W.3
  • 55
    • 0036384894 scopus 로고    scopus 로고
    • Brown adipose tissue: A factor to consider in symmetrical tracer uptake in the neck and upper chest region
    • Hany TF, Gharehpapagh E, Kamel EM, et al. Brown adipose tissue: a factor to consider in symmetrical tracer uptake in the neck and upper chest region. Eur J Nucl Med Mol Imaging 2002; 29:1393-1398.
    • (2002) Eur J Nucl Med Mol Imaging , vol.29 , pp. 1393-1398
    • Hany, T.F.1    Gharehpapagh, E.2    Kamel, E.M.3
  • 56
    • 0037315245 scopus 로고    scopus 로고
    • Uptake in supraclavicular area fat ('USA-Fat'): Description on 18F-FDG PET/CT
    • Cohade C, Osman M, Pannu HK, Wahl RL. Uptake in supraclavicular area fat ('USA-Fat'): description on 18F-FDG PET/CT. J Nucl Med 2003; 44:170-176.
    • (2003) J Nucl Med , vol.44 , pp. 170-176
    • Cohade, C.1    Osman, M.2    Pannu, H.K.3    Wahl, R.L.4
  • 57
    • 64349105205 scopus 로고    scopus 로고
    • Identification and importance of brown adipose tissue in adult humans
    • Cypess AM, Lehman S, Williams G, et al. Identification and importance of brown adipose tissue in adult humans. N Engl J Med 2009; 360:1509-1517.
    • (2009) N Engl J Med , vol.360 , pp. 1509-1517
    • Cypess, A.M.1    Lehman, S.2    Williams, G.3
  • 59
    • 70349334680 scopus 로고    scopus 로고
    • The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue
    • Zingaretti MC, Crosta F, Vitali A, et al. The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue. FASEB J 2009; 23:3113-3120.
    • (2009) FASEB J , vol.23 , pp. 3113-3120
    • Zingaretti, M.C.1    Crosta, F.2    Vitali, A.3
  • 60
    • 26044461959 scopus 로고    scopus 로고
    • Premedication to block [(18)F]FDG uptake in the brown adipose tissue of pediatric and adolescent patients
    • Gelfand MJ, O'hara SM, Curtwright LA, Maclean JR. Premedication to block [(18)F]FDG uptake in the brown adipose tissue of pediatric and adolescent patients. Pediatr Radiol 2005; 35:984-990.
    • (2005) Pediatr Radiol , vol.35 , pp. 984-990
    • Gelfand, M.J.1    O'hara, S.M.2    Curtwright, L.A.3    MacLean, J.R.4
  • 61
    • 0642345828 scopus 로고    scopus 로고
    • Patterns of (18)F-FDG uptake in adipose tissue and muscle: A potential source of false-positives for PET
    • Yeung HW, Grewal RK, Gonen M, et al. Patterns of (18)F-FDG uptake in adipose tissue and muscle: a potential source of false-positives for PET. J Nucl Med 2003; 44:1789-1796.
    • (2003) J Nucl Med , vol.44 , pp. 1789-1796
    • Yeung, H.W.1    Grewal, R.K.2    Gonen, M.3
  • 62
    • 7944236905 scopus 로고    scopus 로고
    • Focal FDG uptake in mediastinal brown fat mimicking malignancy: A potential pitfall resolved on PET/CT
    • Truong MT, Erasmus JJ, Munden RF, et al. Focal FDG uptake in mediastinal brown fat mimicking malignancy: a potential pitfall resolved on PET/CT. AJR Am J Roentgenol 2004; 183:1127-1132.
    • (2004) AJR Am J Roentgenol , vol.183 , pp. 1127-1132
    • Truong, M.T.1    Erasmus, J.J.2    Munden, R.F.3
  • 63
    • 62149130067 scopus 로고    scopus 로고
    • Constant ambient temperature of 24 8C significantly reduces FDG uptake by brown adipose tissue in children scanned during the winter
    • Zukotynski KA, Fahey FH, Laffin S, et al. Constant ambient temperature of 24 8C significantly reduces FDG uptake by brown adipose tissue in children scanned during the winter. Eur J Nucl Med Mol Imaging 2009; 36:602-606.
    • (2009) Eur J Nucl Med Mol Imaging , vol.36 , pp. 602-606
    • Zukotynski, K.A.1    Fahey, F.H.2    Laffin, S.3
  • 64
    • 4043159214 scopus 로고    scopus 로고
    • Intense (18)F-FDG uptake in brown fat can be reduced pharmacologically
    • Tatsumi M, Engles JM, Ishimori T, et al. Intense (18)F-FDG uptake in brown fat can be reduced pharmacologically. J Nucl Med 2004; 45:1189-1193.
    • (2004) J Nucl Med , vol.45 , pp. 1189-1193
    • Tatsumi, M.1    Engles, J.M.2    Ishimori, T.3
  • 65
    • 35348903884 scopus 로고    scopus 로고
    • Comparison of uptake of multiple clinical radiotracers into brown adipose tissue under cold-stimulated and nonstimulated conditions
    • Baba S, Engles JM, Huso DL, et al. Comparison of uptake of multiple clinical radiotracers into brown adipose tissue under cold-stimulated and nonstimulated conditions. J Nucl Med 2007; 48:1715-1723.
    • (2007) J Nucl Med , vol.48 , pp. 1715-1723
    • Baba, S.1    Engles, J.M.2    Huso, D.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.