메뉴 건너뛰기




Volumn 39, Issue 6, 2010, Pages 930-936

Evaluation of the clinical significance of focal adhesion kinase and src expression in human pancreatic ductal adenocarcinoma

Author keywords

FAK; pancreatic cancer; Src

Indexed keywords

FOCAL ADHESION KINASE; PROTEIN TYROSINE PHOSPHATASE SHP;

EID: 77955230400     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPA.0b013e3181d7abcc     Document Type: Article
Times cited : (26)

References (38)
  • 2
    • 77955227695 scopus 로고    scopus 로고
    • Bethesda MD: National Cancer Institute. Updated January 7, 2009, [online database]
    • Pancreatic Cancer Treatment. Bethesda, MD: National Cancer Institute; 1996. Updated January 7, 2009, [online database].
    • (1996) Pancreatic Cancer Treatment
  • 3
    • 8244254377 scopus 로고    scopus 로고
    • Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
    • Burris HA III, Moore MJ, Andersen J, et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol. 1997;15:2403-2413.
    • (1997) J Clin Oncol , vol.15 , pp. 2403-2413
    • Burris III, H.A.1    Moore, M.J.2    Andersen, J.3
  • 4
    • 27644460508 scopus 로고    scopus 로고
    • Erlotinib plus gemcitabine compared to gemcitabine alone in patients with advanced pancreatic cancer
    • A phase III trial of the National Cancer Institute of Canada Clinical Trials Group [NCICCTG]. 2005 ASCO Annual Meeting Proceedings. Vol 23, No. 16S, Part I of II (June 1 Supplement).
    • Moore MJ GD, Hamm J, et al. Erlotinib plus gemcitabine compared to gemcitabine alone in patients with advanced pancreatic cancer. A phase III trial of the National Cancer Institute of Canada Clinical Trials Group [NCICCTG]. J Clin Oncol. 2005;1 2005 ASCO Annual Meeting Proceedings. Vol 23, No. 16S, Part I of II (June 1 Supplement).
    • (2005) J Clin Oncol , vol.1
    • Moore, M.J.G.D.1    Hamm, J.2
  • 5
    • 67649334763 scopus 로고    scopus 로고
    • GEM-CAP: PHASE III radnomised comparison of gemcitabine with gemcitabine plus capecitabine in patients with advanced pancreas cancer
    • #PS11
    • Cunningham DCI, Stocken D, et al. GEM-CAP: PHASE III radnomised comparison of gemcitabine with gemcitabine plus capecitabine in patients with advanced pancreas cancer. ECCO 2005, #PS11.
    • (2005) ECCO
    • Cunningham, D.C.I.1    Stocken, D.2
  • 6
    • 0026759309 scopus 로고
    • Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation
    • Guan JL, Shalloway D. Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation. Nature. 1992;358:690-692.
    • (1992) Nature , vol.358 , pp. 690-692
    • Guan, J.L.1    Shalloway, D.2
  • 7
    • 0026612521 scopus 로고
    • Pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions
    • Schaller MD, Borgman CA, Cobb BS, et al. pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions. Proc Natl Acad Sci U S A. 1992;89:5192-5196.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 5192-5196
    • Schaller, M.D.1    Borgman, C.A.2    Cobb, B.S.3
  • 8
    • 0026674919 scopus 로고
    • Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin
    • Hanks SK, Calalb MB, Harper MC, et al. Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin. Proc Natl Acad Sci U S A. 1992;89:8487-8491.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 8487-8491
    • Hanks, S.K.1    Calalb, M.B.2    Harper, M.C.3
  • 9
    • 0026497659 scopus 로고
    • Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets
    • Lipfert L, Haimovich B, Schaller MD, et al. Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets. J Cell Biol. 1992;119:905-912.
    • (1992) J Cell Biol , vol.119 , pp. 905-912
    • Lipfert, L.1    Haimovich, B.2    Schaller, M.D.3
  • 10
    • 0026700191 scopus 로고
    • Bombesin, vasopressin, and endothelin stimulation of tyrosine phosphorylation in Swiss 3T3 cells. Identification of a novel tyrosine kinase as a major substrate
    • Zachary I, Sinnett-Smith J, Rozengurt E. Bombesin, vasopressin, and endothelin stimulation of tyrosine phosphorylation in Swiss 3T3 cells. Identification of a novel tyrosine kinase as a major substrate. J Biol Chem. 1992;267:19031-19034.
    • (1992) J Biol Chem , vol.267 , pp. 19031-19034
    • Zachary, I.1    Sinnett-Smith, J.2    Rozengurt, E.3
  • 11
  • 12
    • 0028122650 scopus 로고
    • Focal adhesion kinase and associated proteins
    • Schaller MD, Parsons JT. Focal adhesion kinase and associated proteins. Curr Opin Cell Biol. 1994;6:705-710.
    • (1994) Curr Opin Cell Biol , vol.6 , pp. 705-710
    • Schaller, M.D.1    Parsons, J.T.2
  • 13
    • 33845630384 scopus 로고    scopus 로고
    • Focal adhesion kinase signaling pathways regulate the osteogenic differentiation of human mesenchymal stem cells
    • Salasznyk RM, Klees RF, Williams WA, et al. Focal adhesion kinase signaling pathways regulate the osteogenic differentiation of human mesenchymal stem cells. Exp Cell Res. 2007;313:22-37.
    • (2007) Exp Cell Res , vol.313 , pp. 22-37
    • Salasznyk, R.M.1    Klees, R.F.2    Williams, W.A.3
  • 14
    • 0033555070 scopus 로고    scopus 로고
    • Focal adhesion kinase in integrin-mediated signaling
    • Cary LA, Guan JL. Focal adhesion kinase in integrin-mediated signaling. Front Biosci. 1999;4:D102-D113.
    • (1999) Front Biosci , vol.4
    • Cary, L.A.1    Guan, J.L.2
  • 15
    • 0028342938 scopus 로고
    • Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain
    • Xing Z, Chen HC, Nowlen JK, et al. Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain. Mol Biol Cell. 1994;5:413-421.
    • (1994) Mol Biol Cell , vol.5 , pp. 413-421
    • Xing, Z.1    Chen, H.C.2    Nowlen, J.K.3
  • 16
    • 0032509402 scopus 로고    scopus 로고
    • C-Src kinase activity is required for hepatocyte growth factor-induced motility and anchorage-independent growth of mammary carcinoma cells
    • Rahimi N, Hung W, Tremblay E, et al. c-Src kinase activity is required for hepatocyte growth factor-induced motility and anchorage-independent growth of mammary carcinoma cells. J Biol Chem. 1998;273:33714-33721.
    • (1998) J Biol Chem , vol.273 , pp. 33714-33721
    • Rahimi, N.1    Hung, W.2    Tremblay, E.3
  • 17
    • 0035947714 scopus 로고    scopus 로고
    • The v-Src SH3 domain facilitates a cell adhesion-independent association with focal adhesion kinase
    • Hauck CR, Hunter T, Schlaepfer DD. The v-Src SH3 domain facilitates a cell adhesion-independent association with focal adhesion kinase. J Biol Chem. 2001;276:17653-17662.
    • (2001) J Biol Chem , vol.276 , pp. 17653-17662
    • Hauck, C.R.1    Hunter, T.2    Schlaepfer, D.D.3
  • 18
    • 0037150728 scopus 로고    scopus 로고
    • Src in cancer: Deregulation and consequences for cell behaviour
    • Frame MC. Src in cancer: deregulation and consequences for cell behaviour. Biochim Biophys Acta. 2002;1602:114-130.
    • (2002) Biochim Biophys Acta , vol.1602 , pp. 114-130
    • Frame, M.C.1
  • 20
    • 33748068089 scopus 로고    scopus 로고
    • New concepts regarding focal adhesion kinase promotion of cell migration and proliferation
    • Cox BD, Natarajan M, Stettner MR, et al. New concepts regarding focal adhesion kinase promotion of cell migration and proliferation. J Cell Biochem. 2006;99:35-52.
    • (2006) J Cell Biochem , vol.99 , pp. 35-52
    • Cox, B.D.1    Natarajan, M.2    Stettner, M.R.3
  • 21
    • 40349100337 scopus 로고    scopus 로고
    • Clinical significance of FAK expression in human neoplasia. Histology and Histopathology
    • Chatzizacharias NA, Kouraklis GP, Theocharis SE. Clinical significance of FAK expression in human neoplasia. Histology and Histopathology. Histol Histopathol. 2008;23:629-650.
    • (2008) Histol Histopathol , vol.23 , pp. 629-650
    • Chatzizacharias, N.A.1    Kouraklis, G.P.2    Theocharis, S.E.3
  • 22
    • 0038386613 scopus 로고    scopus 로고
    • Src Family kinases in tumor progression and metastasis
    • Summy JM, Gallick GE. Src Family kinases in tumor progression and metastasis. Cancer Metastasis Rev. 2003;22:337-358.
    • (2003) Cancer Metastasis Rev , vol.22 , pp. 337-358
    • Summy, J.M.1    Gallick, G.E.2
  • 24
    • 33745063122 scopus 로고    scopus 로고
    • Src inhibitors as potential therapeutic agents for human cancers
    • Trevino JG, Summy JM, Gallick GE. Src inhibitors as potential therapeutic agents for human cancers. Mini Rev Med Chem. 2006;6:681-687.
    • (2006) Mini Rev Med Chem , vol.6 , pp. 681-687
    • Trevino, J.G.1    Summy, J.M.2    Gallick, G.E.3
  • 25
    • 35349017845 scopus 로고    scopus 로고
    • Phase 1 study of a focal adhesion kinase (FAK) inhibitor PF-00562271 in patients with advanced solid tumors
    • 2007 ASCO Annual Meeting Proceedings
    • Siu LL, Burris HA, Mileshkin L, et al. Phase 1 study of a focal adhesion kinase (FAK) inhibitor PF-00562271 in patients with advanced solid tumors. J Clin Oncol. 2007;25:3527 2007 ASCO Annual Meeting Proceedings.
    • (2007) J Clin Oncol , vol.25 , pp. 3527
    • Siu, L.L.1    Burris, H.A.2    Mileshkin, L.3
  • 28
    • 77955230776 scopus 로고    scopus 로고
    • November 6, Updated February 25, 2009. Available at: Accessed July 1, 2009
    • Phase II Study of Dasatinib in Previously Treated Patients With Advanced NSCLC (TOP0801). [Clinical Trials Web site]. November 6, 2008. Updated February 25, 2009. Available at: http://clinicaltrials.gov/ ct2/show/NCT00787267?term= src&rank=8. Accessed July 1, 2009.
    • (2008) Phase II Study of Dasatinib in Previously Treated Patients with Advanced NSCLC (TOP0801)
  • 29
    • 77955231162 scopus 로고    scopus 로고
    • January 8, Updated April 20, 2009. Available at: Accessed July 1, 2009
    • A Phase I/II Study of Dasatinib and Dacarbazine. [Clinical Trials Web site]. January 8, 2008. Updated April 20, 2009. Available at: http://clinicaltrials.gov/ct2/show/ NCT00597038?term=src+inhibitor&rank=3. Accessed July 1, 2009.
    • (2008) A Phase I/II Study of Dasatinib and Dacarbazine
  • 30
    • 77955229390 scopus 로고    scopus 로고
    • March 5, Updated January 30, 2009. Available at: Accessed July 1, 2009
    • Phase I Dasatinib/Erlotinib in Recurrent NSCLC. [Clinical Trials Web site]. March 5, 2007. Updated January 30, 2009. Available at: http://clinicaltrials.gov/ct2/show/ NCT00444015?term=src+inhibitor&rank=5. Accessed July 1, 2009.
    • (2007) Phase i Dasatinib/Erlotinib in Recurrent NSCLC
  • 31
    • 31544436916 scopus 로고    scopus 로고
    • Clinical significance of focal adhesion kinase in resectable pancreatic cancer
    • Furuyama K, Doi R, Mori T, et al. Clinical significance of focal adhesion kinase in resectable pancreatic cancer. World J Surg. 2006;30:219-226.
    • (2006) World J Surg , vol.30 , pp. 219-226
    • Furuyama, K.1    Doi, R.2    Mori, T.3
  • 32
    • 0345195986 scopus 로고    scopus 로고
    • Overexpression and activation of the tyrosine kinase Src in human pancreatic carcinoma
    • Lutz M, Eber IBC, Flossmann-Kast BBM, et al. Overexpression and activation of the tyrosine kinase Src in human pancreatic carcinoma. Biochem Biophys Res Com. 1998;243:503-508.
    • (1998) Biochem Biophys Res Com , vol.243 , pp. 503-508
    • Lutz, M.1    Eber, I.B.C.2    Flossmann-Kast, B.B.M.3
  • 36
    • 43049122454 scopus 로고    scopus 로고
    • Clinical significance of tumor-associated antigen RCAS1 expression in human pancreatic ductal adenocarcinoma
    • Giaginis C, Davides D, Zarros A, et al. Clinical significance of tumor-associated antigen RCAS1 expression in human pancreatic ductal adenocarcinoma. Dig Dis Sci. 2008;53:1728-1734.
    • (2008) Dig Dis Sci , vol.53 , pp. 1728-1734
    • Giaginis, C.1    Davides, D.2    Zarros, A.3
  • 37
    • 34548158429 scopus 로고    scopus 로고
    • Effect of Src kinase inhibition on metastasis and tumor angiogenesis in human pancreatic cancer
    • Ischenko I, Guba M, Yezhelyev M, et al. Effect of Src kinase inhibition on metastasis and tumor angiogenesis in human pancreatic cancer. Angiogenesis. 2007;10:167-182.
    • (2007) Angiogenesis , vol.10 , pp. 167-182
    • Ischenko, I.1    Guba, M.2    Yezhelyev, M.3
  • 38
    • 57349147100 scopus 로고    scopus 로고
    • Inhibition of Src tyrosine kinase reverts chemoresistance toward 5-fluorouracil in human pancreatic carcinoma cells: An involvement of epidermal growth factor receptor signalling
    • Ischenko I, Camaj P, Seeliger H, et al. Inhibition of Src tyrosine kinase reverts chemoresistance toward 5-fluorouracil in human pancreatic carcinoma cells: an involvement of epidermal growth factor receptor signalling. Oncogene. 2008;27:7212-7222.
    • (2008) Oncogene , vol.27 , pp. 7212-7222
    • Ischenko, I.1    Camaj, P.2    Seeliger, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.