Aqueous extract of Securidaca longepedunculata root induce redox imbalance in male rat liver and kidney

Human and Experimental Toxicology

Volumn 29, Issue 8, 2010, Pages 679-688

  Ajiboye, To ^a   Salau, Ak ^b   Yakubu, Mt ^a   Oladiji, At ^a   Akanji, Ma ^a   Okogun, Ji ^c  

^a UNIVERSITY OF ILORIN   (Nigeria)

^b Osogbo   (Nigeria)

^c NATIONAL INSTITUTE FOR PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (Nigeria)

Author keywords

Antioxidant system; lipid peroxidation; malondialdehyde; redox homeostasis; Securidaca longepedunculata

Indexed keywords

ACID PHOSPHATASE; ALKALINE PHOSPHATASE; ALPHA TOCOPHEROL; ASCORBIC ACID; CATALASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; LIPID HYDROPEROXIDE; MALONALDEHYDE; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; SECURIDACA LONGEPEDUNCULATA EXTRACT; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; WATER;

ACID PHOSPHATASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HOMEOSTASIS; KIDNEY; LIVER; MALE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PLANT ROOT; PRIORITY JOURNAL; RAT; SECURIDACA; SECURIDACA LONGEPEDUNCULATA; SINGLE DRUG DOSE;

ACID PHOSPHATASE; ANIMALS; BODY WEIGHT; HOMEOSTASIS; KIDNEY; LIVER; MALE; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; RATS; SECURIDACA;

ANIMALIA; RATTUS; SECURIDACA LONGEPEDUNCULATA;

EID: 77955216327     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327109357218     Document Type: Article

References (49)

1. Yakubu MT, Akanji MA, Oladiji AT Male sexual dysfunction and methods used in assessing medicinal plants with aphrodisiac potentials. Pharmacog Rev 2007 ; 1: 39-46.
2. Pousset JL Medicinal plants used as a source of raw material for the pharmaceutical industry, problems and prospects. In: Drug production from natural products. Proceedings of the Seventh International Symposium, DRPU, OAU, Ife, Nigeria, 1988, pp. 37-41.
3. Winkleman M., Dobkin de Rios M. Psychoactive properties of kung bushmen medicinal plants. J. Psychoactive Drugs 1989 ; 21: 51-59.
4. Neuwinger HD African ethnobotany, poisons and drugschemistry, pharmocology, toxicology London, UK: Chapman and Hall, 1996, pp. 743-753.
5. Van Wyk BE, Gericke N. A guide to useful plants of southern Africa. Pretoria, South Africa: Briza Publications, 2000.
6. Ojewole Jao. Analgesic, anti-inflammatory and hypoglycaemic effects of Securidaca longepedunculata (Fresen.) [Polygalaceae] root-bark aqueous extract. Inflammopharmacol 2008 ; 15: 174-181.
7. Msonthi JD The status of medicinal plant research and traditional medicine in malaria. In: A Sofowora (ed.) The state of medicinal plants research in Nigeria. Ibadan: University Press, 1986, pp. 335-349.
8. Akinniyi JA, Manawadu D., Sultanbawa M. Ethnobotany and ethnopharmacology of Nigerian medicinal plants research and traditional medicine in malaria. In: A Sofowora (ed.) State of medicinal plants research in Nigeria, Ibadan: University Press, 1996, pp. 35-349.
9. Wannang NN, Wudil AM, Dapar Lmp, Bichi LA Evaluation of anti-snake venom activity of the aqueous root extract of Securidaca longepedunculata in rats. J Pharm Bio Res 2005 ; 2: 80-83.
10. Ekpendu TO, Anyago P., Itywgh D., Akpan F. Niegrian ethnomedicine and medicinal plant flora; The Benue experience - Part 3. Nig J Nat Prod Med 2000 ; 4: 13-22.
11. Van Wyk BE, Van Quadshoom B., Gericke N. Medicinal Plants of South Africa. 1 st ed. Pretoria, South Africa: Briza Publication, 1997, p. 236.
12. Dapar Lpm, Aguiyi CJ, Wannang NN, Gyang SS, Tanko MN The histopathologic effects of Securidaca longepedunculata on heart, liver, kidney and lungs of rats. Afr J Biotech 2007 ; 6: 591-595.
13. Etuk EU, Adebiyi RA, Elsa AT, Agaie BM Acute and subchronic (28) oral toxicity studies of the aqueous root extract of Securidaca longepedunculata Fresen (Polygyalaceace) in mice. Intl J Pharmacol 2006 ; 2: 421-425.
14. Nih. Guide for the care and use of laboratory animals. NIH Publication 1985 ; 83: 127-138.
15. Who, WHO. Basic OECD Principles of GLP. Geneva, Switzerland: World Health Organization. Available at: www.who.int/tdrold/publications/pdf/pr15/info.pdf (access August 2009).
16. Akanji MA, Ngaha EO Effect of repeated administration of berenil on urinary excretion with corresponding tissue pattern in rats. Pharmacol Toxicol 1989 ; 64: 272-275.
17. Hillmann G. Acid phosphatase. Z Klin Chem Klin Biochem 1971 ; 9: 273.
18. German Society for Clinical Chemistry. Recommendations of the German society for clinical chemistry. Z Kim Chem KIm Biochem 1970 ; 8: 659.
19. Misra HP, Fridovich I. The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem 1972 ; 247: 3170-3175.
20. Beers RF Jr., Sizer IW A spectrophotmetric method for measuring breakdown of hydrogen peroxide by catalase. J Biol Chem 1952 ; 195: 133-140.
21. Rotruck JT, Pope AL, Ganther HF, Swason AB Selenium: biochemical role as a component of glutathione peroxidase. Science 1973 ; 179: 588-590.
22. Mavis RD, Stellwagen E. Purification and subunit structure of glutathione reductase from bakersĝ€™ yeast. J Biol Chem 1968 ; 243: 809-814.
23. Ellman GL Tissue sulfhydryl groups. Arch Biochem Biophys 1959 ; 82: 70-77.
24. Omaye ST, Turbull TP, Sauberchich HC Selected methods for determination of ascorbic acid in cells, tissues and fluids. Methods Enzymol 1979 ; 6: 3-11.
25. Desai ID Vitamin E analysis method for animal tissues. Methods Enzymol 1984 ; 105: 138-143.
26. Gornall AC, Bardawill CJ, David MM Determination of serum protein by means of biuret reaction. J Biol Chem 1949 ; 177: 751-756.
27. Buege JA, Aust SD Microsomal lipid peroxidation. Meth Enzymol 1978 ; 52: 302-310.
28. Malomo SO Toxicological implication of ciftriaxone administration in rats. NJBMB 2000 ; 15: 33-38.
29. Akanji MA A comparative biochemical study of the interaction of some trypanosides with rat tissue cellular system. PhD Thesis, University of Ife, Ile-Ife, Nigeria, 1986.
30. Wills DE Evaluation of lipid peroxidation of lipids and biological membranes. In K Snell, B Mullak (eds.) Biochemical toxicology: a pratical approach. Oxford: IRL. Press, 1985.
31. Shahjahan M., Sabitha KE, Mallika J., Shyamala-Devi CS Effect of Solanum trilobatum against carbon tetrachloride induced hepatic damage in albino rats. Indian J Med Res 2004 ; 120: 194-198.
32. Akanji MA, Olagoke OA, Oloyede OB Effect of chronic consumption of metabisulphite on the integrity of rat cellular system. Toxicol 1993 ; 81: 173-179.
33. Malbica JO, Hart LG Effect of adenosine triphosphate (ATP) and some anti-inflammatory agents on purified lysosomal fraction having high acid phosphatase and labile glucuronidase activity. Biochem Pharmacol 1971 ; 20: 2017-2026.
34. Umezawa H., Hooper IR Amino-glycoside antibiotic., Hadelberg, NY: Springer-Verlag Berlin, 1982.
35. Yakubu MT, Olatunji IK, Akanji MA Comparative effects of administration of halofantrine hydrochloride and dihydroartemisinin on some enzymes of selected rat tissues. NISEB J 2002 ; 2: 175-180.
36. Anandakumar P., Kamaraj S., Jagan S., Ramakrishnan G., Devaki T. Lysosomal abnormalities during benzo(a)pyrene-induced experimental lung carcinogenesis - defensive role of capsaicin. Fund Clin Pharmacol 2009 ; 23: 97-103.
37. Butterwort PJ, Moss DW The effect of urea on human kidney alkaline phosphatase. Biochem J 1966 ; 99: 9-10.
38. Akanji MA, Nafiu MO, Yakubu MT Enzyme activities and histopathology of selected tissues in rats treated with potassium bromate. Afr J Biomed Res. 2008 ; 11: 87-95.
39. Sinha M., Manna P., Sil PC Protective effect of arjunolic acid against arsenic-induced oxidative stress in mouse brain. J Biochem Mol Toxicol 2008 ; 22: 15-26.
40. Yen G., Duh P. Scavenging effect of methanolic extract of peanut hulls on free radical and active oxygen species. J Agric Food Chem 1994 ; 42: 629-632.
41. Kono Y., Fridovich I. Superoxide radicals inhibit catalase. J Biol Chem 1982 ; 257: 5751-5754.
42. Ray G., Husain SA Oxidants, antioxidants and carcinogenesis. Indian J Exp Biol 2002 ; 40: 1213-1232.
43. Banmeyer I., Marchand C., Clippe A., Knoops B. Human mitochondrial peroxiredoxin 5 protects from mitochondrial DNA damages induced by hydrogen peroxide. FEBS Lett 2005 ; 579: 2327-2333.
44. Kozer E., Evans S., Bar J., et al. Glutathione, glutathione-dependent enzymes and antioxidant status in erythrocytes from children treated with high-dose paracetamol. Br J Clin Pharmacol 2003 ; 55: 234-240.
45. Pesh-Imam M., Recknagel RO Lipid peroxidation and the concept of anti-oxygenic potential; Vitamin E change in acute experimental CCl4, and ethanol induced liver injury. Toxicol Appl Pharmacol 1977 ; 42: 463-475.
46. Ahluwalia P., Tewari K., Choudhary P. Studies on the effect of monosodium glutamate (MSG) on oxidative stress in erythrocytes of adult male mice. Toxicol Lett 1996 ; 84: 161-165.
47. Kon K., Kim JS, Jaeschke H., Lemasters JJ Mitochondrial permeability transition in acetaminophen-induced necrotic and apoptotic cell death to cultured mouse hepatocytes. Hepatol 2004 ; 40: 1170-1179.
48. Reid AB, Kurten RC, McCullough SS, Brock RW, Hinson JA Mechanisms of acetaminophen-induced hepatotoxicity: role of oxidative stress and mitochondrial permeability transition in freshly isolated mouse hepatocytes. J Pharmacol Exp Ther 2005 ; 312: 509-516.
49. Gujral JS, Knight TR, Farhood A., Bajt ML, Jaeschke H. Mode of cell death after acetaminophen overdose in mice: apoptosis or oncotic necrosis? Toxicol Sci 2002 ; 67: 322-328.