Influence of preoperative chemoradiotherapy on the number of lymph nodes retrieved in rectal cancer

Annals of Surgery

Volumn 252, Issue 2, 2010, Pages 336-340

  Ha, Yun Hyung ^a   Jeong, Seung Yong ^b   Lim, Seok Byung ^c   Choi, Hyo Seong ^a   Hong, Yong Sang ^c   Chang, Hee Jin ^a   Kim, Dae Yong ^a   Jung, Kyung Hae ^c   Park, Jae Gahb ^b  

^a National Cancer Center   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

^c University of Ulsan College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORODEOXYGLUCOSE F 18;

ADULT; ADVANCED CANCER; AGED; ARTICLE; BODY MASS; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; COMPUTER ASSISTED TOMOGRAPHY; DISEASE FREE SURVIVAL; FEMALE; HUMAN; LINEAR REGRESSION ANALYSIS; LYMPH NODE METASTASIS; LYMPHADENECTOMY; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; OVERALL SURVIVAL; POSITRON EMISSION TOMOGRAPHY; PREOPERATIVE CARE; PRIORITY JOURNAL; RADIATION DOSE FRACTIONATION; RECTUM CANCER; RETROSPECTIVE STUDY; TREATMENT OUTCOME; UNIVARIATE ANALYSIS;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; COMBINED MODALITY THERAPY; FEMALE; HUMANS; LYMPH NODE EXCISION; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; RADIOTHERAPY DOSAGE; RECTAL NEOPLASMS; REGRESSION ANALYSIS; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 77955175519     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0b013e3181e61e33     Document Type: Article

References (26)

1. Greene FL, American Joint Committee on Cancer. AJCC Cancer Staging Manual. New York, NY: Springer; 2002.
2. Kapiteijn E, Marijnen CA, Nagtegaal ID, et al. Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N Engl J Med. 2001;345:638-646.
3. Sauer R, Becker H, Hohenberger W, et al. Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med. 2004;351:1731-1740.
4. Baxter NN, Morris AM, Rothenberger DA, et al. Impact of preoperative radiation for rectal cancer on subsequent lymph node evaluation: a population-based analysis. Int J Radiat Oncol Biol Phys. 2005;61:426-431.
5. Cummings BJ. Effect of preoperative radiochemotherapy on lymph node retrieval after resection of rectal cancer. Tech Coloproctol. 2002;6:134-135.
6. Thorn CC, Woodcock NP, Scott N, et al. What factors affect lymph node yield in surgery for rectal cancer? Colorectal Dis. 2004;6:356-361.
7. Kim DY, Jung KH, Kim TH, et al. Comparison of 5-fluorouracil/leucovorin and capecitabine in preoperative chemoradiotherapy for locally advanced rectal cancer. Int J Radiat Oncol Biol Phys. 2007;67:378-384.
8. Lim SB, Heo SC, Lee MR, et al. Changes in outcome with sphincter preserving surgery for rectal cancer in Korea, 1991-2000. Eur J Surg Oncol. 2005;31:242-249.
9. Dworak O, Keilholz L, Hoffmann A. Pathological features of rectal cancer after preoperative radiochemotherapy. Int J Colorectal Dis. 1997;12:19-23.
10. Pocard M, Panis Y, Malassagne B, et al. Assessing the effectiveness of mesorectal excision in rectal cancer: prognostic value of the number of lymph nodes found in resected specimens. Dis Colon Rectum. 1998;41:839-845.
11. Tepper JE, O'Connell MJ, Niedzwiecki D, et al. Impact of number of nodes retrieved on outcome in patients with rectal cancer. J Clin Oncol. 2001;19: 157-163.
12. Baxter NN, Virnig DJ, Rothenberger DA, et al. Lymph node evaluation in colorectal cancer patients: a population-based study. J Natl Cancer Inst. 2005;97:219-225.
13. Wright FC, Law CH, Last L, et al. Lymph node retrieval and assessment in stage II colorectal cancer: a population-based study. Ann Surg Oncol. 2003; 10:903-909.
14. Gorog D, Nagy P, Peter A, et al. Influence of obesity on lymph node recovery from rectal resection specimens. Pathol Oncol Res. 2003;9:180-183.
15. Sarli L, Bader G, Iusco D, et al. Number of lymph nodes examined and prognosis of TNM stage II colorectal cancer. Eur J Cancer. 2005;41:272-279.
16. Morris EJ, Maughan NJ, Forman D, et al. Identifying stage III colorectal cancer patients: the influence of the patient, surgeon, and pathologist. J Clin Oncol. 2007;25:2573-2579.
17. Wichmann MW, Muller C, Meyer G, et al. Effect of preoperative radioche-motherapy on lymph node retrieval after resection of rectal cancer. Arch Surg. 2002;137:206-210. (Pubitemid 34142139)
18. Johnson PM, Malatjalian D, Porter GA. Adequacy of nodal harvest in colorectal cancer: a consecutive cohort study. J Gastrointest Surg. 2002;6: 883-888; discussion 889-890.
19. Lim SB, Choi HS, Jeong SY, et al. Optimal surgery time after preoperative chemoradiotherapy for locally advanced rectal cancers. Ann Surg. 2008;248: 243-251.
20. Baxendall M, Lewis F. Disappearing lymph nodes: one explanation for the fall in number with increasing age. J Pathol 2005;208:29A.
21. Marr R, Birbeck K, Garvican J, et al. The modern abdominoperineal excision: the next challenge after total mesorectal excision. Ann Surg. 2005;242:74-82.
22. Tekkis PP, Smith JJ, Heriot AG, et al. A national study on lymph node retrieval in resectional surgery for colorectal cancer. Dis Colon Rectum. 2006;49:1673-1683.
23. Wong JH, Severino R, Honnebier MB, et al. Number of nodes examined and staging accuracy in colorectal carcinoma. J Clin Oncol. 1999;17:2896-2900.
24. Rullier A, Laurent C, Capdepont M, et al. Lymph nodes after preoperative chemoradiotherapy for rectal carcinoma: number, status, and impact on survival. Am J Surg Pathol. 2008;32:45-50.
25. Luna-Perez P, Rodriguez-Ramirez S, Alvarado I, et al. Prognostic significance of retrieved lymph nodes per specimen in resected rectal adenocarci-noma after preoperative chemoradiation therapy. Arch Med Res. 2003;34: 281-286.
26. Scott N, Thorne C, Jayne D. Lymph node retrieval after neoadjuvant radiotherapy for rectal adenocarcinoma. J Clin Pathol. 2004;57:335-336.