-
1
-
-
0038664390
-
Comparative immunogenicity in rhesus monkeys of DNA plasmid, recombinant vaccinia virus, and replication-defective adenovirus vectors expressing a human immunodefciency virus type 1 gag gene
-
Casimiro, DR, Chen, L, Fu, TM, Evans, RK, Caulfeld, MJ, Davies, ME et al. (2003). Comparative immunogenicity in rhesus monkeys of DNA plasmid, recombinant vaccinia virus, and replication-defective adenovirus vectors expressing a human immunodefciency virus type 1 gag gene. J Virol 77: 6305-6313.
-
(2003)
J Virol
, vol.77
, pp. 6305-6313
-
-
Casimiro, D.R.1
Chen, L.2
Fu, T.M.3
Evans, R.K.4
Caulfeld, M.J.5
Davies, M.E.6
-
2
-
-
43949099690
-
Merck V520-016 Study Group. (2008) Safety and immunogenicity of a replication-incompetent adenovirus type 5 HIV-1 clade B gag/pol/nef vaccine in healthy adults
-
Priddy, FH, Brown, D, Kublin, J, Monahan, K, Wright, DP, Lalezari, J et al.; Merck V520-016 Study Group. (2008). Safety and immunogenicity of a replication-incompetent adenovirus type 5 HIV-1 clade B gag/pol/nef vaccine in healthy adults. Clin Infect Dis 46: 1769-1781.
-
Clin Infect Dis
, vol.46
, pp. 1769-1781
-
-
Priddy, F.H.1
Brown, D.2
Kublin, J.3
Monahan, K.4
Wright, D.P.5
Lalezari, J.6
-
3
-
-
33845439080
-
Vaccine Research Center 006 Study Team. (2006). Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector
-
Catanzaro, AT, Koup, RA, Roederer, M, Bailer, RT, Enama, ME, Moodie, Z et al.; Vaccine Research Center 006 Study Team. (2006). Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector. J Infect Dis 194: 1638-1649.
-
J Infect Dis
, vol.194
, pp. 1638-1649
-
-
Catanzaro, A.T.1
Koup, R.A.2
Roederer, M.3
Bailer, R.T.4
Enama, M.E.5
Moodie, Z.6
-
4
-
-
0037122719
-
Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodefciency-virus immunity
-
Shiver, JW, Fu, TM, Chen, L, Casimiro, DR, Davies, ME, Evans, RK et al. (2002). Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodefciency-virus immunity. Nature 415: 331-335.
-
(2002)
Nature
, vol.415
, pp. 331-335
-
-
Shiver, J.W.1
Fu, T.M.2
Chen, L.3
Casimiro, D.R.4
Davies, M.E.5
Evans, R.K.6
-
5
-
-
56649105122
-
Step Study Protocol Team. (2008). Effcacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): A double-blind, randomised, placebo-controlled, test-of-concept trial
-
Buchbinder, SP, Mehrotra, DV, Duerr, A, Fitzgerald, DW, Mogg, R, Li, D et al.; Step Study Protocol Team. (2008). Effcacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial. Lancet 372: 1881-1893.
-
Lancet
, vol.372
, pp. 1881-1893
-
-
Buchbinder, S.P.1
Mehrotra, D.V.2
Duerr, A.3
Fitzgerald, D.W.4
Mogg, R.5
Li, D.6
-
6
-
-
56649114351
-
Step Study Protocol Team. (2008). HIV-1 vaccine-induced immunity in the test-of-concept Step Study: A case-cohort analysis
-
McElrath, MJ, De Rosa, SC, Moodie, Z, Dubey, S, Kierstead, L, Janes, H et al.; Step Study Protocol Team. (2008). HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis. Lancet 372: 1894-1905.
-
Lancet
, vol.372
, pp. 1894-1905
-
-
McElrath, M.J.1
De Rosa, S.C.2
Moodie, Z.3
Dubey, S.4
Kierstead, L.5
Janes, H.6
-
8
-
-
68349135329
-
Adenovirus-specifc immunity after immunization with an Ad5 HIV-1 vaccine candidate in humans
-
O'Brien, KL, Liu, J, King, SL, Sun, YH, Schmitz, JE, Lifton, MA et al. (2009). Adenovirus-specifc immunity after immunization with an Ad5 HIV-1 vaccine candidate in humans. Nat Med 15: 873-875.
-
(2009)
Nat Med
, vol.15
, pp. 873-875
-
-
O'Brien, K.L.1
Liu, J.2
King, S.L.3
Sun, Y.H.4
Schmitz, J.E.5
Lifton, M.A.6
-
9
-
-
44749083247
-
Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques
-
Hirao, LA, Wu, L, Khan, AS, Hokey, DA, Yan, J, Dai, A et al. (2008). Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques. Vaccine 26: 3112-3120.
-
(2008)
Vaccine
, vol.26
, pp. 3112-3120
-
-
Hirao, L.A.1
Wu, L.2
Khan, A.S.3
Hokey, D.A.4
Yan, J.5
Dai, A.6
-
10
-
-
29244455769
-
Attenuation of simian immunodefciency virus SIVmac239 infection by prophylactic immunization with dna and recombinant adenoviral vaccine vectors expressing Gag
-
Casimiro, DR, Wang, F, Schleif, WA, Liang, X, Zhang, ZQ, Tobery, TW et al. (2005). Attenuation of simian immunodefciency virus SIVmac239 infection by prophylactic immunization with dna and recombinant adenoviral vaccine vectors expressing Gag. J Virol 79: 15547-15555.
-
(2005)
J Virol
, vol.79
, pp. 15547-15555
-
-
Casimiro, D.R.1
Wang, F.2
Schleif, W.A.3
Liang, X.4
Zhang, Z.Q.5
Tobery, T.W.6
-
12
-
-
20944444088
-
Replication-defective adenovirus serotype 5 vectors elicit durable cellular and humoral immune responses in nonhuman primates
-
Santra, S, Seaman, MS, Xu, L, Barouch, DH, Lord, CI, Lifton, MA et al. (2005). Replication-defective adenovirus serotype 5 vectors elicit durable cellular and humoral immune responses in nonhuman primates. J Virol 79: 6516-6522.
-
(2005)
J Virol
, vol.79
, pp. 6516-6522
-
-
Santra, S.1
Seaman, M.S.2
Xu, L.3
Barouch, D.H.4
Lord, C.I.5
Lifton, M.A.6
-
13
-
-
0034755765
-
Multiple effects of codon usage optimization on expression and immunogenicity of DNA candidate vaccines encoding the human immunodefciency virus type 1 Gag protein
-
Deml, L, Bojak, A, Steck, S, Graf, M, Wild, J, Schirmbeck, R et al. (2001). Multiple effects of codon usage optimization on expression and immunogenicity of DNA candidate vaccines encoding the human immunodefciency virus type 1 Gag protein. J Virol 75: 10991-11001.
-
(2001)
J Virol
, vol.75
, pp. 10991-11001
-
-
Deml, L.1
Bojak, A.2
Steck, S.3
Graf, M.4
Wild, J.5
Schirmbeck, R.6
-
14
-
-
0031906148
-
Increased immune response elicited by DNA vaccination with a synthetic gp120 sequence with optimized codon usage
-
André, S, Seed, B, Eberle, J, Schraut, W, Bültmann, A and Haas, J (1998). Increased immune response elicited by DNA vaccination with a synthetic gp120 sequence with optimized codon usage. J Virol 72: 1497-1503.
-
(1998)
J Virol
, vol.72
, pp. 1497-1503
-
-
André, S.1
Seed, B.2
Eberle, J.3
Schraut, W.4
Bültmann, A.5
Haas, J.6
-
15
-
-
0030960338
-
Inactivation of the human immunodefciency virus type 1 inhibitory elements allows Rev-independent expression of Gag and Gag/protease and particle formation
-
Schneider, R, Campbell, M, Nasioulas, G, Felber, BK and Pavlakis, GN (1997). Inactivation of the human immunodefciency virus type 1 inhibitory elements allows Rev-independent expression of Gag and Gag/protease and particle formation. J Virol 71: 4892-4903.
-
(1997)
J Virol
, vol.71
, pp. 4892-4903
-
-
Schneider, R.1
Campbell, M.2
Nasioulas, G.3
Felber, B.K.4
Pavlakis, G.N.5
-
16
-
-
37549037877
-
Intradermal/subcutaneous immunization by electroporation improves plasmid vaccine delivery and potency in pigs and rhesus macaques
-
Hirao, LA, Wu, L, Khan, AS, Satishchandran, A, Draghia-Akli, R and Weiner, DB (2008). Intradermal/subcutaneous immunization by electroporation improves plasmid vaccine delivery and potency in pigs and rhesus macaques. Vaccine 26: 440-448.
-
(2008)
Vaccine
, vol.26
, pp. 440-448
-
-
Hirao, L.A.1
Wu, L.2
Khan, A.S.3
Satishchandran, A.4
Draghia-Akli, R.5
Weiner, D.B.6
-
17
-
-
2942564030
-
Enhancement of DNA vaccine potency in rhesus macaques by electroporation
-
Otten, G, Schaefer, M, Doe, B, Liu, H, Srivastava, I, zur Megede, J et al. (2004). Enhancement of DNA vaccine potency in rhesus macaques by electroporation. Vaccine 22: 2489-2493.
-
(2004)
Vaccine
, vol.22
, pp. 2489-2493
-
-
Otten, G.1
Schaefer, M.2
Doe, B.3
Liu, H.4
Srivastava, I.5
Megede, J.6
-
18
-
-
33646852606
-
Potent immunogenicity of an HIV-1 gag-pol fusion DNA vaccine delivered by in vivo electroporation
-
Otten, GR, Schaefer, M, Doe, B, Liu, H, Megede, JZ, Donnelly, J et al. (2006). Potent immunogenicity of an HIV-1 gag-pol fusion DNA vaccine delivered by in vivo electroporation. Vaccine 24: 4503-4509.
-
(2006)
Vaccine
, vol.24
, pp. 4503-4509
-
-
Otten, G.R.1
Schaefer, M.2
Doe, B.3
Liu, H.4
Megede, J.Z.5
Donnelly, J.6
-
19
-
-
34248382494
-
Effect of plasmid DNA vaccine design and in vivo electroporation on the resulting vaccine-specifc immune responses in rhesus macaques
-
Luckay, A, Sidhu, MK, Kjeken, R, Megati, S, Chong, SY, Roopchand, V et al. (2007). Effect of plasmid DNA vaccine design and in vivo electroporation on the resulting vaccine-specifc immune responses in rhesus macaques. J Virol 81: 5257-5269.
-
(2007)
J Virol
, vol.81
, pp. 5257-5269
-
-
Luckay, A.1
Sidhu, M.K.2
Kjeken, R.3
Megati, S.4
Chong, S.Y.5
Roopchand, V.6
-
20
-
-
70349471292
-
DNA vaccination in rhesus macaques induces potent immune responses and decreases acute and chronic viremia after SIVmac251 challenge
-
Rosati, M, Bergamaschi, C, Valentin, A, Kulkarni, V, Jalah, R, Alicea, C et al. (2009). DNA vaccination in rhesus macaques induces potent immune responses and decreases acute and chronic viremia after SIVmac251 challenge. Proc Natl Acad Sci USA 106: 15831-15836.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 15831-15836
-
-
Rosati, M.1
Bergamaschi, C.2
Valentin, A.3
Kulkarni, V.4
Jalah, R.5
Alicea, C.6
-
21
-
-
67349094564
-
Novel SIVmac DNA vaccines encoding Env, Pol and Gag consensus proteins elicit strong cellular immune responses in cynomolgus macaques
-
Yan, J, Hokey, DA, Morrow, M P, Corbitt, N, Harris, K, Harris, D et al. (2009). Novel SIVmac DNA vaccines encoding Env, Pol and Gag consensus proteins elicit strong cellular immune responses in cynomolgus macaques. Vaccine 27: 3260-3266.
-
(2009)
Vaccine
, vol.27
, pp. 3260-3266
-
-
Yan, J.1
Hokey, D.A.2
Morrow, M.P.3
Corbitt, N.4
Harris, K.5
Harris, D.6
-
22
-
-
21044439669
-
Neutralizing antibodies to adenovirus serotype 5 vaccine vectors are directed primarily against the adenovirus hexon protein
-
Sumida, SM, Truitt, DM, Lemckert, AA, Vogels, R, Custers, JH, Addo, MM et al. (2005). Neutralizing antibodies to adenovirus serotype 5 vaccine vectors are directed primarily against the adenovirus hexon protein. J Immunol 174: 7179-7185.
-
(2005)
J Immunol
, vol.174
, pp. 7179-7185
-
-
Sumida, S.M.1
Truitt, D.M.2
Lemckert, A.A.3
Vogels, R.4
Custers, J.H.5
Addo, M.M.6
-
23
-
-
43249127622
-
Magnitude and phenotype of cellular immune responses elicited by recombinant adenovirus vectors and heterologous prime-boost regimens in rhesus monkeys
-
Liu, J, Ewald, BA, Lynch, DM, Denholtz, M, Abbink, P, Lemckert, AA et al. (2008). Magnitude and phenotype of cellular immune responses elicited by recombinant adenovirus vectors and heterologous prime-boost regimens in rhesus monkeys. J Virol 82: 4844-4852.
-
(2008)
J Virol
, vol.82
, pp. 4844-4852
-
-
Liu, J.1
Ewald, B.A.2
Lynch, D.M.3
Denholtz, M.4
Abbink, P.5
Lemckert, A.A.6
-
24
-
-
58149267963
-
Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys
-
Liu, J, O'Brien, KL, Lynch, DM, Simmons, NL, La Porte, A, Riggs, AM et al. (2009). Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys. Nature 457: 87-91.
-
(2009)
Nature
, vol.457
, pp. 87-91
-
-
Liu, J.1
O'Brien, K.L.2
Lynch, D.M.3
Simmons, N.L.4
La Porte, A.5
Riggs, A.M.6
-
25
-
-
35448968969
-
Human immunodefciency virus type 1 controllers but not noncontrollers maintain CD4 T cells coexpressing three cytokines
-
Kannanganat, S, Kapogiannis, BG, Ibegbu, C, Chennareddi, L, Goepfert, P, Robinson, HL et al. (2007). Human immunodefciency virus type 1 controllers but not noncontrollers maintain CD4 T cells coexpressing three cytokines. J Virol 81: 12071-12076.
-
(2007)
J Virol
, vol.81
, pp. 12071-12076
-
-
Kannanganat, S.1
Kapogiannis, B.G.2
Ibegbu, C.3
Chennareddi, L.4
Goepfert, P.5
Robinson, H.L.6
-
27
-
-
27644489746
-
Phenotypic, functional, and kinetic parameters associated with apparent T-cell control of human immunodefciency virus replication in individuals with and without antiretroviral treatment
-
Emu, B, Sinclair, E, Favre, D, Moretto, WJ, Hsue, P, Hoh, R et al. (2005). Phenotypic, functional, and kinetic parameters associated with apparent T-cell control of human immunodefciency virus replication in individuals with and without antiretroviral treatment. J Virol 79: 14169-14178.
-
(2005)
J Virol
, vol.79
, pp. 14169-14178
-
-
Emu, B.1
Sinclair, E.2
Favre, D.3
Moretto, W.J.4
Hsue, P.5
Hoh, R.6
-
30
-
-
49149120457
-
DNA gag/adenovirus type 5 (Ad5) gag and Ad5 gag/Ad5 gag vaccines induce distinct T-cell response profles
-
Cox, KS, Clair, JH, Prokop, MT, Sykes, KJ, Dubey, SA, Shiver, JW et al. (2008). DNA gag/adenovirus type 5 (Ad5) gag and Ad5 gag/Ad5 gag vaccines induce distinct T-cell response profles. J Virol 82: 8161-8171.
-
(2008)
J Virol
, vol.82
, pp. 8161-8171
-
-
Cox, K.S.1
Clair, J.H.2
Prokop, M.T.3
Sykes, K.J.4
Dubey, S.A.5
Shiver, J.W.6
-
31
-
-
0022410222
-
Synthetic oligonucleotide probes deduced from amino acid sequence data. Theoretical and practical considerations
-
Lathe, R (1985). Synthetic oligonucleotide probes deduced from amino acid sequence data. Theoretical and practical considerations. J Mol Biol 183: 1-12.
-
(1985)
J Mol Biol
, vol.183
, pp. 1-12
-
-
Lathe, R.1
-
32
-
-
0003518435
-
-
Los Alamos National Laboratory: Los Alamos, NM
-
Korber, B, Kuiken, C, Foley, B, Hahn, B, McCutchan, F, Mellors, J et al. (1998). Human Retroviruses and AIDS. Los Alamos National Laboratory: Los Alamos, NM.
-
(1998)
Human Retroviruses and AIDS
-
-
Korber, B.1
Kuiken, C.2
Foley, B.3
Hahn, B.4
McCutchan, F.5
Mellors, J.6
-
33
-
-
0023251351
-
Site-specifc mutagenesis of AIDS virus reverse transcriptase
-
Larder, BA, Purifoy, DJ, Powell, KL and Darby, G (1987). Site-specifc mutagenesis of AIDS virus reverse transcriptase. Nature 327: 716-717.
-
(1987)
Nature
, vol.327
, pp. 716-717
-
-
Larder, B.A.1
Purifoy, D.J.2
Powell, K.L.3
Darby, G.4
-
34
-
-
0024706946
-
Infectious potential of human immunodefciency virus type 1 reverse transcriptase mutants with altered inhibitor sensitivity
-
Larder, BA, Kemp, SD and Purifoy, DJ (1989). Infectious potential of human immunodefciency virus type 1 reverse transcriptase mutants with altered inhibitor sensitivity. Proc Natl Acad Sci USA 86: 4803-4807.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 4803-4807
-
-
Larder, B.A.1
Kemp, S.D.2
Purifoy, D.J.3
-
35
-
-
0025908083
-
Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase
-
Davies, JF 2nd, Hostomska, Z, Hostomsky, Z, Jordan, SR and Matthews, DA (1991). Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase. Science 252: 88-95.
-
(1991)
Science
, vol.252
, pp. 88-95
-
-
Davies, I.I.J.F.1
Hostomska, Z.2
Hostomsky, Z.3
Jordan, S.R.4
Matthews, D.A.5
-
36
-
-
0024847468
-
Point mutations in conserved amino acid residues within the C-terminal domain of HIV-1 reverse transcriptase specifcally repress RNase H function
-
Schatz, O, Cromme, FV, Grüninger-Leitch, F and Le Grice, SF (1989). Point mutations in conserved amino acid residues within the C-terminal domain of HIV-1 reverse transcriptase specifcally repress RNase H function. FEBS Lett 257: 311-314.
-
(1989)
FEBS Lett
, vol.257
, pp. 311-314
-
-
Schatz, O.1
Cromme, F.V.2
Grüninger-Leitch, F.3
Le Grice, S.F.4
-
37
-
-
0025093302
-
Site-directed mutagenesis of the conserved Asp-443 and Asp-498 carboxy-terminal residues of HIV-1 reverse transcriptase
-
Mizrahi, V, Usdin, MT, Harington, A and Dudding, LR (1990). Site-directed mutagenesis of the conserved Asp-443 and Asp-498 carboxy-terminal residues of HIV-1 reverse transcriptase. Nucleic Acids Res 18: 5359-5363.
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 5359-5363
-
-
Mizrahi, V.1
Usdin, M.T.2
Harington, A.3
Dudding, L.R.4
-
38
-
-
0027470432
-
Site-directed mutagenesis of HIV-1 integrase demonstrates differential effects on integrase functions in vitro
-
Leavitt, AD, Shiue, L and Varmus, HE (1993). Site-directed mutagenesis of HIV-1 integrase demonstrates differential effects on integrase functions in vitro. J Biol Chem 268: 2113-2119.
-
(1993)
J Biol Chem
, vol.268
, pp. 2113-2119
-
-
Leavitt, A.D.1
Shiue, L.2
Varmus, H.E.3
-
39
-
-
0028924020
-
Human immunodefciency virus type 1 integrase: Effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells
-
Wiskerchen, M and Muesing, MA (1995). Human immunodefciency virus type 1 integrase: effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells. J Virol 69: 376-386.
-
(1995)
J Virol
, vol.69
, pp. 376-386
-
-
Wiskerchen, M.1
Muesing, M.A.2
-
40
-
-
0038235693
-
Comparative analysis of the effects of packaging signal, transgene orientation, promoters, polyadenylation signals, and E3 region on growth properties of frst-generation adenoviruses
-
Youil, R, Toner, TJ, Su, Q, Casimiro, D, Shiver, JW, Chen, L et al. (2003). Comparative analysis of the effects of packaging signal, transgene orientation, promoters, polyadenylation signals, and E3 region on growth properties of frst-generation adenoviruses. Hum Gene Ther 14: 1017-1034.
-
(2003)
Hum Gene Ther
, vol.14
, pp. 1017-1034
-
-
Youil, R.1
Toner, T.J.2
Su, Q.3
Casimiro, D.4
Shiver, J.W.5
Chen, L.6
-
41
-
-
0025866787
-
Effect of intron A from human cytomegalovirus (Towne) immediate-early gene on heterologous expression in mammalian cells
-
Chapman, BS, Thayer, RM, Vincent, KA and Haigwood, NL (1991). Effect of intron A from human cytomegalovirus (Towne) immediate-early gene on heterologous expression in mammalian cells. Nucleic Acids Res 19: 3979-3986.
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 3979-3986
-
-
Chapman, B.S.1
Thayer, R.M.2
Vincent, K.A.3
Haigwood, N.L.4
-
42
-
-
0026742969
-
The 3'-fanking sequence of the bovine growth hormone gene contains novel elements required for effcient and accurate polyadenylation
-
Goodwin, EC and Rottman, FM (1992). The 3'-fanking sequence of the bovine growth hormone gene contains novel elements required for effcient and accurate polyadenylation. J Biol Chem 267: 16330-16334.
-
(1992)
J Biol Chem
, vol.267
, pp. 16330-16334
-
-
Goodwin, E.C.1
Rottman, F.M.2
|