The metabolic enzyme CTP synthase forms cytoskeletal filaments

Nature Cell Biology

Volumn 12, Issue 8, 2010, Pages 739-746

  Ingerson Mahar, Michael ^a   Briegel, Ariane ^b   Werner, John N ^a   Jensen, Grant J ^b   Gitai, Zemer ^a  

^a PRINCETON UNIVERSITY   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CRESCENTIN; CYTIDINE TRIPHOSPHATE SYNTHASE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL CELL; CAULOBACTER CRESCENTUS; CONTROLLED STUDY; CYTOSKELETON; ESCHERICHIA COLI; IN VITRO STUDY; IN VIVO STUDY; INTERMEDIATE FILAMENT; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION;

BACTERIAL PROTEINS; CARBON-NITROGEN LIGASES; CAULOBACTER CRESCENTUS; CYTOSKELETON; MICROSCOPY, FLUORESCENCE; MICROSCOPY, PHASE-CONTRAST; PROTEIN BINDING;

BACTERIA (MICROORGANISMS); CAULOBACTER VIBRIOIDES; ESCHERICHIA COLI; EUKARYOTA;

EID: 77955143027     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb2087     Document Type: Article

References (26)

1. Bi, E. F. & Lutkenhaus, J. FtsZ ring structure associated with division in Escherichia coli. Nature 354, 161-164 (1991).
2. Lowe, J. & Amos, L. A. Crystal structure of the bacterial cell-division protein FtsZ. Nature 391, 203-206 (1998). (Pubitemid 28092483)
3. Jones, L. J., Carballido-Lopez, R. & Errington, J. Control of cell shape in bacteria: helical, actin-like filaments in Bacillus subtilis. Cell 104, 913-922 (2001).
4. Ausmees, N., Kuhn, J. R. & Jacobs-Wagner, C. The bacterial cytoskeleton: an intermediate filament-like function in cell shape. Cell 115, 705-713 (2003).
5. Briegel, A. et al. Multiple large filament bundles observed in Caulobacter crescentus by electron cryotomography. Mol. Microbiol. 62, 5-14 (2006).
6. Li, Z. & Jensen, G. J. Electron cryotomography: a new view into microbial ultrastructure. Curr. Opin. Microbiol. 12, 333-340 (2009).
7. Li, Z., Trimble, M. J., Brun, Y. V. & Jensen, G. J. The structure of FtsZ filaments in vivo suggests a force-generating role in cell division. EMBO J. 26, 4694-4708 (2007).
8. Werner, J. N. et al. Quantitative genome-scale analysis of protein localization in an asymmetric bacterium. Proc. Natl Acad. Sci. USA 106, 7858-7863 (2009).
9. Long, C. W., Levitzki, A. & Koshland, D. E., Jr. The subunit structure and subu-nit interactions of cytidine triphosphate synthetase. J. Biol. Chem. 245, 80-87 (1970).
10. Briegel, A. et al. Location and architecture of the Caulobacter crescentus chemoreceptor array. Mol. Microbiol. 69, 30-41 (2008).
11. Ma, X., Ehrhardt, D. W. & Margolin, W. Colocalization of cell division proteins FtsZ and FtsA to cytoskeletal structures in living Escherichia coli cells by using green fluorescent protein. Proc. Natl Acad. Sci. USA 93, 12998-13003 (1996).
12. Gitai, Z., Dye, N. & Shapiro, L. An actin-like gene can determine cell polarity in bacteria. Proc. Natl Acad. Sci. USA 101, 8643-8648 (2004).
13. Hartman, S. C. The interaction of 6-diazo-5-oxo-l-norleucine with phosphoribosyl pyro-phosphate amidotransferase. J. Biol. Chem. 238, 3036-3047 (1963).
14. Karimova, G., Pidoux, J., Ullmann, A. & Ladant, D. A bacterial two-hybrid system based on a reconstituted signal transduction pathway. Proc. Natl Acad. Sci. USA 95, 5752-5756 (1998).
15. Srinivasan, R., Mishra, M., Murata-Hori, M. & Balasubramanian, M. K. Filament formation of the Escherichia coli actin-related protein, MreB, in fission yeast. Curr. Biol. 17, 266-272 (2007).
16. Srinivasan, R., Mishra, M., Wu, L., Yin, Z. & Balasubramanian, M. K. The bacterial cell division protein FtsZ assembles into cytoplasmic rings in fission yeast. Genes Dev. 22, 1741-1746 (2008).
17. Levitzki, A. & Koshland, D. E., Jr. Cytidine triphosphate synthetase. Covalent intermediates and mechanisms of action. Biochemistry 10, 3365-3371 (1971).
18. Endrizzi, J. A., Kim, H., Anderson, P. M. & Baldwin, E. P. Crystal structure of Escherichia coli cytidine triphosphate synthetase, a nucleotide-regulated glutamine amidotrans-ferase/ATP-dependent amidoligase fusion protein and homologue of anticancer and antiparasitic drug targets. Biochemistry 43, 6447-6463 (2004).
19. Lunn, F. A., Macleod, T. J. & Bearne, S. L. Mutational analysis of conserved glycine residues 142, 143 and 146 reveals Gly(142) is critical for tetramerization of CTP synthase from Escherichia coli. Biochem. J. 412, 113-121 (2008).
20. Paluh, J. L., Zalkin, H., Betsch, D. & Weith, H. L. Study of anthranilate synthase function by replacement of cysteine 84 using site-directed mutagenesis. J. Biol. Chem. 260, 1889-1894 (1985).
21. Charbon, G., Cabeen, M. T. & Jacobs-Wagner, C. Bacterial intermediate filaments: in vivo assembly, organization, and dynamics of crescentin. Genes Dev. 23, 1131-1144 (2009).
22. Cabeen, M. T. et al. Bacterial cell curvature through mechanical control of cell growth. EMBO J. 28, 1208-1219 (2009).
23. Kleinschmidt, A. K., Moss, J. & Lane, D. M. Acetyl coenzyme A carboxylase: filamentous nat of the animal enzymes. Science 166, 1276-1278 (1969).
24. Carrey, E. A. et al. Detection and location of the enzymes of de novo pyrimidine biosynthesis in mammalian spermatozoa. Reproduction 123, 757-768 (2002).
25. Zigler, J. S., Jr. & Rao, P. V. Enzyme/crystallins and extremely high pyridine nucleotide levels in the eye lens. FASEB J. 5, 223-225 (1991).
26. Bork, P., Sander, C. & Valencia, A. An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin and hsp70 heat shock proteins. Proc. Natl Acad. Sci. USA 89, 7290-7294 (1992).