Evidence for a common genetic aetiology in high-risk families with multiple haematological malignancy subtypes

British Journal of Haematology

Volumn 150, Issue 4, 2010, Pages 456-462

  Tegg, Elizabeth M ^a,b   Thomson, Russell J ^a   Stankovich, Jim ^a   Banks, Annette ^a   Flowers, Ceri ^a   McWhirter, Rebekah ^a   Panton, Jean ^a   Piaszczyk, Anne ^a   Bahlo, Melanie ^a,c   Marsden, Katherine A ^a,b   Lowenthal, Ray M ^a,b   Foote, Simon J ^a   Dickinson, Joanne L ^a  

^a UNIVERSITY OF TASMANIA   (Australia)

^b ROYAL HOBART HOSPITAL   (Australia)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

aetiology; familial haematological malignancy; genetics

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AGED; ARTICLE; CANCER CLASSIFICATION; CANCER RISK; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ASSESSMENT; CONTROLLED STUDY; FLOW CYTOMETRY; GENETIC ANALYSIS; HISTOPATHOLOGY; HODGKIN DISEASE; HUMAN; MAJOR CLINICAL STUDY; MYELODYSPLASTIC SYNDROME; MYELOPROLIFERATIVE DISORDER; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; CHILD; CHILD, PRESCHOOL; HEMATOLOGIC NEOPLASMS; HUMANS; INFANT; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MIDDLE AGED; NEOPLASTIC SYNDROMES, HEREDITARY; PEDIGREE; REGISTRIES; TASMANIA; YOUNG ADULT;

EID: 77955141312     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2010.08267.x     Document Type: Article

References (26)

1. Abecasis, G.R. Wigginton, J.E. (2005) Handling Marker-Marker Linkage Disequilibrium: Pedigree Analysis with Clustered Markers. The American Journal of Human Genetics, 77, 754 767.
2. Akintola-Ogunremi, O., Whitney, C., Mathur, S.C. Finch, C.N. (2002) Chronic lymphocytic leukemia presenting with symptomatic central nervous system involvement. Annals of Hematology, 81, 402 404.
3. Castor, A., Nilsson, L., Astrand-Grundstrom, I., Buitenhuis, M., Ramirez, C., Anderson, K., Strombeck, B., Garwicz, S., Bekassy, A.N., Schmiegelow, K., Lausen, B., Hokland, P., Lehmann, S., Juliusson, G., Johansson, B. Jacobsen, S.E.W. (2005) Distinct patterns of hematopoietic stem cell involvement in acute lymphoblastic leukemia. Nature Medicine, 11, 630 637.
4. Chang, E.T., Smedby, K.E., Hjalgrim, H., Porwit-MacDonald, A., Roos, G., Glimelius, B. Adami, H.-O. (2005) Family History of Hematopoietic Malignancy and Risk of Lymphoma. Journal of the National Cancer Institute, 97, 1466 1474.
5. Drach, J., Schuster, J., Nowotny, H., Angerler, J., Rosenthal, F., Fiegl, M., Rothermundt, C., Gsur, A., Jager, U., Heinz, R., Lechner, K., Ludwig, H. Huber, H. (1995) Multiple myeloma: high incidence of chromosomal aneuploidy as detected by interphase fluorescence in situ hybridization. Cancer Research, 55, 3854 3859.
6. FitzGerald, L.M., Patterson, B., Thomson, R., Polanowski, A., Quinn, S., Brohede, J., Thornton, T., Challis, D., Mackey, D.A., Dwyer, T., Foote, S., Hannan, G.N., Stankovich, J., McKay, J.D. Dickinson, J.L. (2008) Identification of a prostate cancer susceptibility gene on chromosome 5p13q12 associated with risk of both familial and sporadic disease. European Journal of Human Genetics, 368 377.
7. Fuller, S.J., Papaemmanuil, E., McKinnon, L., Webb, E., Sellick, G.S., Dao-Ung, L., Skarratt, K.K., Crowther, D., Houlston, R.S. Wiley, J.S. (2008) Analysis of a large multi-generational family provides insight into the genetics of chronic lymphocytic leukemia. British journal of Haematology, 142, 238 245.
8. Gilbert, H. (1998) Familial myeloproliferative disease. In : Bailliëre's Clinical Haematology (ed. by A.R. Green T.C. Pearson Vol. 11, pp. 849 858. Elsevier Ltd., London, UK.
9. Giles, G.G., Lickiss, J.N., Baikie, M.J., Lowenthal, R.M. Panton, J. (1984) Myeloproliferative and lymphoproliferative disorders in Tasmania, 1972-80: occupational and familial aspects. Journal of the National Cancer Institute, 72, 1233 1240.
10. Goldgar, D.E., Easton, D.F., Cannon-Albright, L.A. Skolnick, M.H. (1994) Systematic population-based assessment of cancer risk in first-degree relatives of cancer probands. Journal of the National Cancer Institute, 86, 1600 1608.
11. Goldin, L.R., Pfeiffer, R.M., Li, X. Hemminki, K. (2004) Familial risk of lymphoproliferative tumors in families of patients with chronic lymphocytic leukemia: results from the Swedish family-cancer database. Blood, 104, 1850 1854.
12. Grosbois, B., Jego, P., Attal, M., Payen, C., Rapp, M.J., Panton, J., Fuzibet, G., Maigre, M. Bataille, R. (1999) Familial multiple myeloma: report of fifteen families. British Journal of Haematology, 105, 768 770.
13. Houlston, R.S., Sellick, G., Yuille, M., Matutes, E. Catovsky, D. (2003) Causation of chronic lymphocytic leukemia - insights from familial disease. Leukemia Research, 27, 871 876.
14. Lickiss, J.N., Baikie, A.G. Panton, J. (1977) Lymphoproliferative and myeloproliferative disease in Tasmania. Journal of the National Cancer Institute. Monographs, 47, 37 39.
15. Lynch, H.T., Ferrara, K., Barlogie, B., Coleman, E.A., Lynch, J.F., Weisenburger, D., Sanger, W., Watson, P., Nipper, H., Witt, V. Thome, S. (2008) Familial Myeloma. New England Journal of Medicine, 359, 152 157.
16. Mauro, F.R., Giammartini, E., Gentile, M., Sperduti, I., Valle, V., Pizzuti, A., Guarini, A., Giannarelli, D. Foa, R. (2006) Clinical features and outcome of familial chronic lymphocytic leukemia. Haematologica, 91, 1117 1120.
17. Mensah, F.K., Willett, E.V., Ansell, P., Adamson, P.J. Roman, E. (2007) Non-Hodgkin's lymphoma and family history of hematologic malignancy. American Journal of Epidemiology, 165, 126 133.
18. Rawstron, A.C., Yuille, M.R., Fuller, J., Cullen, M., Kennedy, B., Richards, S.J., Jack, A.S., Matutes, E., Catovsky, D., Hillmen, P. Houlston, R.S. (2002) Inherited predisposition to CLL is detectable as subclinical monoclonal B-lymphocyte expansion. Blood, 100, 2289 2290.
19. Rowley, J.D. (2008) Chromosomal translocations: revisited yet again. Blood, 112, 2183 2189.
20. Rubio, J.P., Bahlo, M., Butzkueven, H., van der Mei, I.A.F., Sale, M.M., Dickinson, J.L., Groom, P., Johnson, L.J., Simmons, R.D., Tait, B., Varney, M., Taylor, B., Dwyer, T., Williamson, R., Gough, N.M., Kilpatrick, T.J., Speed, T.P. Foote, S.J. (2002) Genetic dissection of the human leukocyte antigen region by use of haplotypes of Tasmanians with multiple sclerosis. The American Journal of Human Genetics, 70, 1125 1137.
21. Schoch, C., Haase, D., Fonatsch, C., Haferlach, T., Loffler, H., Schlegelberger, B., Hossfeld, D., Becher, R., Sauerland, M.C., Heinecke, A., Womann, B., Buchner, T. Hiddemann, W. (1997) The significance of trisomy 8 in de novo acute myeloid leukaemia: the accompanying chromosome aberrations determine the prognosis. British Journal of Haematology, 99, 605 611.
22. Segel, G.B. Lichtman, M.A. (2004) Familial (inherited) leukemia, lymphoma, and myeloma: an overview. Blood Cells, Molecules, and Diseases, 32, 246 261.
23. Shpilberg, O., Modan, M., Modan, B., Chetrit, A., Fuchs, Z. Ramot, B. (1994) Familial aggregation of haematological neoplasms: a controlled study. British Journal of Haematology, 87, 75 80.
24. Sloand, E.M., Pfannes, L., Chen, G., Shah, S., Solomou, E.E., Barrett, J. Young, N.S. (2007) CD34 cells from patients with trisomy 8 myelodysplastic syndrome (MDS) express early apoptotic markers but avoid programmed cell death by up-regulation of antiapoptotic proteins. Blood, 109, 2399 2405.
25. Swerdlow, S.H., Campo, E., Harris, N.L., Jaffe, E.S., Pileri, S.A., Stein, H., Thiele, J. Vardiman, J.W. (ed.) (2008) WHO classification of Tumours of Haematopoietic and Lymphoid Tissues. International Agency for Research on Cancer (IARC), Lyon France, pp. 1 439.
26. Yuille, M.R., Matutes, E., Marossy, A., Hilditch, B., Catovsky, D. Houlston, R.S. (2001) Familial chronic lymphocytic leukaemia: a survey and review of published studes. British Journal of Haematology, 109, 794 799.