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Volumn 53, Issue 5-6, 2010, Pages 291-294
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When should we worry about compounds with potential reactive metabolites?
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Author keywords
ALK; NVP TAE684; Reactive metabolites
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Indexed keywords
BIOMOLECULES;
DRUG PRODUCTS;
METABOLITES;
REACTION INTERMEDIATES;
ADDUCT FORMATION;
ALK;
DRUG CANDIDATES;
HEPATIC INJURY;
IN-VITRO;
LATE STAGE;
NVP-TAE684;
REACTIVE INTERMEDIATE;
REACTIVE METABOLITES;
VITRO METHOD;
FREE RADICALS;
CYSTEINE;
FREE RADICAL;
GLUTATHIONE;
NVP TAE684;
PROTEIN TYROSINE KINASE INHIBITOR;
REACTIVE OXYGEN METABOLITE;
TRITIUM;
UNCLASSIFIED DRUG;
ACETYLATION;
ANTINEOPLASTIC ACTIVITY;
CARDIOTOXICITY;
CONFERENCE PAPER;
COVALENT BOND;
DEALKYLATION;
DNA ADDUCT;
DRUG ABSORPTION;
DRUG DISTRIBUTION;
DRUG EFFICACY;
DRUG EXCRETION;
DRUG METABOLISM;
DRUG STRUCTURE;
GENOTOXICITY;
GLUCOSE INTOLERANCE;
GLUCURONIDATION;
HUMAN;
ISOTOPE LABELING;
LIVER CELL;
LIVER MICROSOME;
LIVER TOXICITY;
METABOLIC ACTIVATION;
METHYLATION;
NONHUMAN;
OXIDATION;
OXIDATIVE STRESS;
PHYSICAL CHEMISTRY;
RADIOACTIVITY;
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EID: 77955136886
PISSN: 03624803
EISSN: 10991344
Source Type: Journal
DOI: None Document Type: Conference Paper |
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Times cited : (2)
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References (3)
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