The syntheses and in vitro metabolism of [14C]Apixaban, an inhibitor of blood coagulation FXA

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 53, Issue 5-6, 2010, Pages 363-367

  Maxwell, Brad D ^a   Tran, Scott B ^a   Chen, Shiang Yuan ^a   Zhang, Donglu ^a   Chen, Bang Chi ^a   Zhang, Huiping ^a   Bonacorsi, Samuel J ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

ADME; Apixaban; Factor Xa; Hepatocytes; Microsomes; Thrombotic diseases

Indexed keywords

BLOOD; COAGULATION;

ADME; APIXABAN; BLOOD COAGULATION; COAGULATION FACTOR; FACTOR XA; HEPATOCYTES; IN-VITRO; MICROSOME; POTENT INHIBITOR; THROMBOTIC DISEASE;

METABOLISM;

7 ETHYLCOUMARIN; APIXABAN; CARBON 14; COUMARIN DERIVATIVE; HYMECROMONE; UNCLASSIFIED DRUG;

ANIMAL CELL; CONFERENCE PAPER; DRUG ABSORPTION; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG METABOLISM; DRUG PURIFICATION; DRUG SYNTHESIS; DRUG TRANSFORMATION; HUMAN; HUMAN CELL; IN VITRO STUDY; ISOTOPE LABELING; LIVER CELL; LIVER MICROSOME; NONHUMAN; RAT;

EID: 77955134173     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1771     Document Type: Conference Paper

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