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Volumn 5, Issue 8, 2010, Pages 1242-1246

Hit identification and biological evaluation of anticancer pyrazolopyrimidines endowed with anti-inflammatory activity

(9) Alcaro, Stefano a Artese, Anna a Botta, Maurizio b Zizzari, Alessandra T b Orallo, Francisco c Ortuso, Francesco a Schenone, Silvia d Brullo, Chiara d Yáñez, Matilde c

a UNIVERSITY MAGNA GRAECIA OF CATANZARO (Italy)

b UNIVERSITY OF SIENA (Italy)

c UNIVERSITY OF SANTIAGO DE COMPOSTELA (Spain)

d UNIVERSITY OF GENOA (Italy)

Author keywords

COX; Dual activity; Enantiomeric separation; Pyrazolopyrimidines; Virtual screening

Indexed keywords

5 BROMO 2 (4 FLUOROPHENYL) 3 (4 METHYLSULFONYLPHENYL)THIOPHENE; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; DICLOFENAC; INDOMETACIN; PYRAZOLOPYRIMIDINE DERIVATIVE;

ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; COMPARATIVE STUDY; DRUG IDENTIFICATION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; PRIORITY JOURNAL;

ANTI-INFLAMMATORY AGENTS; ANTINEOPLASTIC AGENTS; BINDING SITES; CELL LINE, TUMOR; COMPUTER SIMULATION; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; HUMANS; NEOPLASMS; PYRAZOLES; PYRIDINES;

EID: 77955108539 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201000165 Document Type: Article

Times cited : (28)

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