Molecular docking and 3D-QSAR studies on triazolinone and pyridazinone, non-nucleoside inhibitor of HIV-1 reverse transcriptase

Journal of Molecular Modeling

Volumn 16, Issue 6, 2010, Pages 1169-1178

  Sivan, Sree Kanth ^a   Manga, Vijjulatha ^a  

^a OSMANIA UNIVERSITY   (India)

Author keywords

CoMFA(Comparative molecular field analysis); CoMSIA (Comparative molecular similarity indices analysis); Docking; HIV 1 reverse transcriptase; Non nucleoside inhibitors; Pyridazinones; Triazolinones

Indexed keywords

NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; PYRIDAZINONE DERIVATIVE; TRIAZOLINE DERIVATIVE;

ARTICLE; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROPHOBICITY; MOLECULAR DOCKING; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RELIABILITY;

COMPUTER SIMULATION; DRUG DESIGN; HIV INFECTIONS; HIV REVERSE TRANSCRIPTASE; HIV-1; HUMANS; HYDROGEN BONDING; HYDROPHOBICITY; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PYRIDAZINES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; REVERSE TRANSCRIPTASE INHIBITORS; TRIAZOLES;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 77955097051     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-009-0625-8     Document Type: Article

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