The 1.3 isoform of Na+-Ca2+ exchanger expressed in guinea pig tracheal smooth muscle is less sensitive to KB-R7943

Journal of Physiology and Biochemistry

Volumn 66, Issue 2, 2010, Pages 117-125

  Algara Suárez, Paola ^a   Mejía Elizondo, Rebeca ^a   Sims, Stephen M ^b   Saavedra Alanis, Victor M ^a   Espinosa Tanguma, Ricardo ^a  

^a UNIVERSIDAD AUTÓNOMA DE SAN LUIS POTOSÍ   (Mexico)

^b WESTERN UNIVERSITY   (Canada)

Author keywords

Airway smooth muscle; Guinea pig; Isoform; KB R7943; NCX

Indexed keywords

2 [2 [4 (4 NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA METHANESULFONATE; ASPARTIC ACID; GLUTAMIC ACID; LEUCINE; NIFEDIPINE; PHENYLALANINE; SODIUM CALCIUM EXCHANGE PROTEIN;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; EXON; GUINEA PIG; MOLECULAR BIOLOGY; MUSCLE CONTRACTION; MUSCLE RELAXATION; NONHUMAN; NUCLEOTIDE SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE; TRACHEA;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CALCIUM; GUINEA PIGS; MALE; MOLECULAR SEQUENCE DATA; MUSCLE CONTRACTION; MUSCLE RELAXATION; MYOCYTES, SMOOTH MUSCLE; PROTEIN ISOFORMS; SODIUM-CALCIUM EXCHANGER; THIOUREA; TRACHEA;

CAVIA;

EID: 77955096704     PISSN: 11387548     EISSN: 18778755     Source Type: Journal    
DOI: 10.1007/s13105-010-0016-8     Document Type: Article

References (29)

1. 2+ exchanger and non-selective cation channels during histamine stimulation in guinea-pig tracheal smooth muscle. Am J Physiol Lung Cell Mol Physiol 293:L191-L198.
2. Berridge M (2008) Smooth muscle cell calcium activation mechanisms. J Physiol 586(21):5047-5061.
3. 2+ current in canine ventricular cardiomyocytes. Naunyn Schmiedebergs Arch Pharmacol 372:63-70.
4. Blaustein MP, Lederer W (1999) Sodium/calcium exchange: its physiological implications. Physiol Rev 79:763-854.
5. Braun HI (1994) The collected works of John W. Turkey. Chapman and Hall, New York.
6. D'Agostino RB, Belanger A, D'Agostino RB Jr (1990) A suggestion for using the powerful and informative test of normality. Am Stat 44:316-321.
7. 2+ (NCX1) isoforms. J Biol Chem 277:33957- 33962.
8. 2+)i changes in guinea pig tracheal smooth muscle cells in culture: effects of Na+and ouabain. J Physiol Biochem 59:25-33.
9. Espinosa-Tanguma R, Valle-Aguilera JR, Zarazua-Garcia O, Navarro-Huerta MP, Pecina C, Sanchez-Armass S (2004) Mechanism of ouabain-induced contractions in guinea-pig tracheal rings. Clin Exp Pharmacol Physiol 31:710-715.
10. 2+ exchanger in rat astrocytes and neurons by PKA. J Neurosci 18:4833-4841.
11. Hilgemann DW (2004) New insights into the molecular and cellular workings of the cardiac Na+/Ca2+ exchanger. Am J Physiol Cell Physiol 287:C1167-C1172.
12. Hirota S, Helli P, Janssen LJ (2007) Ionic mechanisms and Ca2+ handling in airway smooth muscle. Eur Respir J 30:114-133.
13. + mobilization. Am J Physiol Lung Cell Mol Physiol 292:L438-L447.
14. 2+ exchange (NCX1) inhibition by SEA0400. J Biol Chem 279:7544-7553.
15. 2+ exchange in cells expressing NCX1. J Biol Chem 21:22391-22397.
16. 2+ exchange mechanisms. Am J Physiol 273: L322-L330.
17. 2+ exchanger. Am J Physiol 263:C1241-C1249.
18. Kofuji P, LedererWJ, Schulze DH (1994) Mutually exclusive and cassette exons underlie alternatively spliced isoforms of the Na/Ca exchanger. J Biol Chem 269:5145-5149.
19. 2+ exchanger isoforms. J Biol Chem 269:14849- 14852.
20. 2+ exchanger. J Biol Chem 269:17434-17439.
21. Liang GH, Kim JA, Seol GH, Choi S, Suh SH (2007) The Na(+)/Ca(2+) exchanger inhibitor KB-R7943 activates large-conductance Ca(2+)-activated K(+) channels in endothelial and vascular smooth muscle cells. Eur J Pharmacol 582:35-41.
22. Mejía-Elizondo R, Espinosa-Tanguma R, Saavedra-Alanis VM (2002) Molecular identification of the NCX isoform expressed in tracheal smooth muscle of guinea pig. Ann NY Acad Sci 976:73-76.
23. 2+ exchanger. Science 250:562-565.
24. 2+ exchanger. NCX3. J Biol Chem 271:24914-24921.
25. 2+ exchanger in the guinea pig cochlea. Biochem Biophys Res Commun 233:737-741.
26. Philipson KD, Nicoll DA (2000) Sodium-calcium exchange: a molecular perspective. Annu Rev Physiol 62:111-133.
27. 2+ exchanger. Am J Respir Cell Mol Biol 15:726-730.
28. Sanderson MJ, Delmotte P, Bai Y, Perez-Zogbhi JF (2008) Regulation of airway smooth muscle cell contractility by Ca2+ signaling and sensitivity. Proc Am Thorac Soc 5:23- 31.
29. Shapiro SS, Wilk MB (1965) An analysis of variance test for normality: complete samples. Biometrika 52:591-611.