Positive predictive value of anti-HCMV IgM as an index of primary infection

Journal of Virological Methods

Volumn 168, Issue 1-2, 2010, Pages 121-125

  De Paschale, Massimo ^a   Agrappi, Carlo ^a   Manco, Maria Teresa ^a   Clerici, Pierangelo ^a  

^a Hospital of Legnano   (Italy)

Author keywords

Anti HCMV IgM; ELFA; ELISA; IgG avidity; Predictive value

Indexed keywords

CYTOMEGALOVIRUS ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; VIRUS ANTIBODY;

ADOLESCENT; ADULT; AGED; ANTIBODY DETECTION; ANTIBODY SCREENING; ANTIBODY SPECIFICITY; ARTICLE; CHILD; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; IMMUNOFLUORESCENCE TEST; INTERMETHOD COMPARISON; MALE; NONHUMAN; PREDICTOR VARIABLE; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; ANTIBODY AFFINITY; BLOOD; COMPARATIVE STUDY; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; EVALUATION STUDY; IMMUNOLOGY; INFANT; MIDDLE AGED; PREDICTIVE VALUE; PREGNANCY; PROCEDURES; VERY ELDERLY; VIROLOGY; YOUNG ADULT;

HUMAN HERPESVIRUS 5;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, VIRAL; ANTIBODY AFFINITY; CHILD; CHILD, PRESCHOOL; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INFANT; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PREGNANCY; VIROLOGY; YOUNG ADULT;

EID: 77955094575     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jviromet.2010.05.001     Document Type: Article

References (27)

1. Baccard-Longere M., Freymuth F., Cointe D., Seigneurin J.M., Grangeot-Keros L. Multicenter evaluation of a rapid and convenient method for determination of Cytomegalovirus immunoglobulin G avidity. Clin. Diagn. Lab. Immunol. 2001, 8:429-431.
2. Blackburn N.K., Besselaar T.G., Schoub B.D., O'Connell K.F. Differentiation of primary cytomegalovirus infection from reactivation using the urea denaturation test for measuring antibody avidity. J. Med. Virol. 1994, 33:6-9.
3. Boppana S.B., Rivera L.B., Fowler K.B., Mach M., Britt W.J. Intrauterine transmission of cytomegalovirus to infants of women with preconceptional immunity. N. Engl. J. Med. 2001, 344:1366-1371.
4. Carles M.J., Enault C., Lachaud L., Charachon S. Comparative evaluation of the vidas and liaison toxoplasmosis, cytomegalovirus and rubella panels in a French university hospital. Clin. Microbiol. Infect. 2006, 12(Suppl. 4):P648.
5. Champsaur H., Fattal-German M., Arranhado R. Sensitivity and specificity of viral immunoglobulin M determination by indirect enzyme-linked immunosorbent assay. J. Clin. Microbiol. 1988, 26:328-332.
6. Desmottes P., Thulliez P., Vauloup-Fellouz C., Grangeot-Keros L. Evaluation of the VIDAS, LIAISON and AxSYM CMV IgG & IgM reagents on routine and interfering samples. Proceedings of the 2008 Congenital Cytomegalovirus Conference, CDC 2008, 38.
7. Deyi Y.M., Goubau P., Bodéus M. False-positive IgM antibody tests for cytomegalovirus in patients with acute Epstein-Barr virus infection. Eur. J. Clin. Microbiol. Infect. Dis. 2000, 19:557-560.
8. Fowler K.B., Stagno S., Pass R.F., Britt W.J., Boll T.J., Alford C.A. The outcome of congenital cytomegalovirus infection in relation to maternal antibody status. N. Engl. J. Med. 1992, 326:663-667.
9. Fowler K.B., Stagno S., Pass R.F. Maternal immunity and prevention of congenital cytomegalovirus infection. JAMA 2003, 289:1008-1011.
10. Grangeot-Keros L., Mayaux M.J., Lebon P., Freymuth F., Eugene G., Stricker R., Dussaix E. Value of cytomegalovirus (CMV) IgG avidity index for the diagnosis of primary CMV infection in pregnant women. J. Infect. Dis. 1997, 175:944-946.
11. Gratacap-Cavallier C.B., Bosson J.L., Morand P., Dutertre N., Chanzy B., Jouk P.S., Vandekerckhove C., Cart-Lamy L.P., Seigneurin J.M. Cytomegalovirus seroprevalence in French pregnant women: parity and place of birth as major predictive factors. Eur. J. Epidemiol. 1998, 14:147-152.
12. Griffiths P.D., Babboonian C., Rutter D., Peckham C. Congenital and maternal cytomegalovirus infections in a London population. Br. J. Obstet. Gynaecol. 1991, 98:135-140.
13. Griffiths P.D. Strategies to prevent CMV infection in the neonate. Semin. Neonatol. 2002, 7:293-299.
14. Hize S., Parker S., Onde U. Seroprevalence of Cytomegalovirus infection among children and females of Ankara, Turkey, 1995. Pediatr. Int. 1999, 41:506-509.
15. Lazzarotto T., Spezzacatena P., Pradelli P., Abate D.A., Varani S., Landini M.P. Avidity of immunoglobulin G directed against human cytomagalovirus during primary and secondary infections in immunocompetent and immunocompromised subjects. Clin. Diagn. Lab. Immunol. 1997, 4:469-473.
16. Lazzarotto T., Spezzacatena P., Pradelli P., Abate D.A., Gabrielli L., Varani S., Landini M.P. Cytomegalovirus infection in pregnancy: a still complicated diagnostic problem. Intervirology 1998, 41:149-157.
17. Lazzarotto T., Guerra B., Lanari M., Gabrielli L., Landini M.P. New advances in the diagnosis of congenital cytomegalovirus infection. J. Clin. Virol. 2008, 41:192-197.
18. Naot Y., Barnett E.V., Remington J.S. Method for avoiding false-positive results occurring in immunoglobulin M enzyme-linked immunosorbent assay due to presence of both rheumatoid factor and antinuclear antibodies. J. Clin. Microbiol. 1981, 14:73-78.
19. Nielsen S.L., Sørensen I., Andersen H.K. Kinetics of specific immunoglobulins M, E, A, and G in congenital, primary, and secondary cytomegalovirus infection studied by antibody-capture enzyme-linked immunosorbent assay. J. Clin. Microbiol. 1988, 26:654-661.
20. Revello M.G., Percivalle E., Zannino M., Rossi V., Gerna G. Development and evaluation of a capture ELISA for IgM antibody to the human cytomegalovirus major DNA binding protein. J. Virol. Methods 1991, 35:315-329.
21. Revello M.G., Gerna G. Diagnosis and implications of human cytomegalovirus infection in pregnancy. Fetal Matern. Med. Rev. 1999, 11:117-134.
22. Revello M.G., Gerna G. Diagnosis and management of human Cytomagalovirus infection in the mother, fetus and newborn infant. Clin. Microbiol. Rev. 2002, 15:680-715.
23. Revello M.G., Gorini G., Gerna G. Clinical evaluation of a chemiluminescence immunoassay for determination of immunoglobulin G avidity to human Cytomegalovirus. Clin. Diagn. Lab. Immunol. 2004, 11:801-805.
24. Stagno S., Pass R.F., Dworsky M.E., Hendersen R.E., Moore E.G., Walton P.D., Alford C.A. Congenital cytomegalovirus infection. The relative importance of primary and recurrent maternal infection. N. Eng. J. Med. 1982, 306:945-949.
25. Stagno S., Pass R.F., Cloud G., Britt W.J., Henderson R.E., Walton P.D., Veren D.A., Page F., Alford C.A. Primary cytomegalovirus infection in pregnancy: incidence, transmission to fetus and clinical outcome. JAMA 1986, 256:1904-1908.
26. Venkitaraman A.R., Seigneurin J.M., Lenoir G.M., John T.J. Infections due to the human herpes-viruses in Southern India: a seroepidemiological survey. Int. J. Epidemiol. 1986, 15:561-566.
27. Wen L., Wu S., Lu S. The epidemiological study on human cytomegalovirus infection in pregnant women and the maternal-fetal transmission in three Chinese metropolis. Zhonghua Fu Chan Ke Za Zhi 1996, 31:714-717.