메뉴 건너뛰기




Volumn 12, Issue 3, 2010, Pages 403-413

Prothrombin complex concentrates for oral anticoagulant therapy-related intracranial hemorrhage: A review of the literature

Author keywords

Coagulopathy; Intracerebral hemorrhage; Intracranial bleeding; Intracranial hemorrhage; Oral anticoagulation; Prothrombin complex concentrates; Vitamin K antagonists; Warfarin

Indexed keywords

ANTICOAGULANT AGENT; ANTITHROMBIN III; BERIPLEX P N; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 9; BLOOD CLOTTING FACTOR 9 COMPLEX; BLOOD CLOTTING FACTOR 9 CONCENTRATE; COFACT; D DIMER; FATTY ACID BINDING PROTEIN; FIBRINOGEN; FRESH FROZEN PLASMA; HEPARIN; OCTAPLEX; PLACEBO; PPSB HT NICHIYAKU; PROPLEX T; PROTEIN C; PROTEIN S; PROTHROMBIN; PROTHROMBIN COMPLEX; PROTHROMBINEX HT; RECOMBINANT BLOOD CLOTTING FACTOR 7A; THROMBIN; UNCLASSIFIED DRUG; VITAMIN K GROUP; WARFARIN;

EID: 77955094322     PISSN: 15416933     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12028-009-9310-0     Document Type: Review
Times cited : (84)

References (75)
  • 1
    • 0035892035 scopus 로고    scopus 로고
    • A comparison of warfarin and aspirin for the prevention of recurrent ischemic stroke
    • Mohr JP, Thompson JL, Lazar RM, Levin B, Sacco RL, Furie KL, et al. A comparison of warfarin and aspirin for the prevention of recurrent ischemic stroke. N Engl J Med. 2001;345(20):1444-1451
    • (2001) N Engl J Med , vol.345 , Issue.20 , pp. 1444-1451
    • Mohr, J.P.1    Thompson, J.L.2    Lazar, R.M.3    Levin, B.4    Sacco, R.L.5    Furie, K.L.6
  • 2
    • 0029147740 scopus 로고
    • Oral anticoagulants and intracranial hemorrhage. Facts and hypotheses
    • Hart RG, Boop BS, Anderson DC. Oral anticoagulants and intracranial hemorrhage. Facts and hypotheses. Stroke. 1995; 26(8):1471-1477
    • (1995) Stroke , vol.26 , Issue.8 , pp. 1471-1477
    • Hart, R.G.1    Boop, B.S.2    Anderson, D.C.3
  • 3
    • 0031949613 scopus 로고    scopus 로고
    • Management of oral anticoagulant-induced intracranial haemorrhage
    • Butler AC, Tait RC. Management of oral anticoagulant-induced intracranial haemorrhage. Blood Rev. 1998;12(1):35-44.
    • (1998) Blood Rev , vol.12 , Issue.1 , pp. 35-44
    • Butler, A.C.1    Tait, R.C.2
  • 4
    • 0028343127 scopus 로고
    • Risk factors for intracranial hemorrhage in outpatients taking warfarin
    • Hylek EM, Singer DE. Risk factors for intracranial hemorrhage in outpatients taking warfarin. Ann Intern Med. 1994;120(11):897-902.
    • (1994) Ann Intern Med , vol.120 , Issue.11 , pp. 897-902
    • Hylek, E.M.1    Singer, D.E.2
  • 5
    • 0142151552 scopus 로고    scopus 로고
    • Comparison of ximelagatran with warfarin for the prevention of venous thromboembolism after total knee replacement
    • Francis CW, Berkowitz SD, Comp PC, Lieberman JR, Ginsberg JS, Paiement G, et al. Comparison of ximelagatran with warfarin for the prevention of venous thromboembolism after total knee replacement. N Engl J Med. 2003;349(18):1703- 1712
    • (2003) N Engl J Med , vol.349 , Issue.18 , pp. 1703-1712
    • Francis, C.W.1    Berkowitz, S.D.2    Comp, P.C.3    Lieberman, J.R.4    Ginsberg, J.S.5    Paiement, G.6
  • 6
    • 2042485525 scopus 로고    scopus 로고
    • Preinjury warfarin use among elderly patients with closed head injuries in a trauma center
    • Lavoie A, Ratte S, Clas D, Demers J, Moore L, Martin M, et al. Preinjury warfarin use among elderly patients with closed head injuries in a trauma center. J Trauma. 2004;56(4):802-807
    • (2004) J Trauma , vol.56 , Issue.4 , pp. 802-807
    • Lavoie, A.1    Ratte, S.2    Clas, D.3    Demers, J.4    Moore, L.5    Martin, M.6
  • 7
    • 0037665024 scopus 로고    scopus 로고
    • Complications of preinjury warfarin use in the trauma patient
    • Mina AA, Bair HA, Howells GA, Bendick PJ. Complications of preinjury warfarin use in the trauma patient. J Trauma. 2003 ;54(5):842-847
    • (2003) J Trauma , vol.54 , Issue.5 , pp. 842-847
    • Mina, A.A.1    Bair, H.A.2    Howells, G.A.3    Bendick, P.J.4
  • 10
    • 0025787541 scopus 로고
    • Prognostic parameters in spontaneous intracerebral hematomas with special reference to anticoagulant treatment
    • Radberg JA, Olsson JE, Radberg CT. Prognostic parameters in spontaneous intracerebral hematomas with special reference to anticoagulant treatment. Stroke. 1991;22(5):571-576
    • (1991) Stroke , vol.22 , Issue.5 , pp. 571-576
    • Radberg, J.A.1    Olsson, J.E.2    Radberg, C.T.3
  • 11
    • 33644878260 scopus 로고    scopus 로고
    • Intracerebral hemorrhage associated with oral anticoagulant therapy: current practices and unresolved questions
    • Steiner T, Rosand J, Diringer M. Intracerebral hemorrhage associated with oral anticoagulant therapy: current practices and unresolved questions. Stroke. 2006;37(1):256-262
    • (2006) Stroke , vol.37 , Issue.1 , pp. 256-262
    • Steiner, T.1    Rosand, J.2    Diringer, M.3
  • 12
    • 4644230838 scopus 로고    scopus 로고
    • Warfarin, hematoma expansion, and outcome of intracerebral hemorrhage
    • Flibotte JJ, Hagan N, O'Donnell J, Greenberg SM, Rosand J. Warfarin, hematoma expansion, and outcome of intracerebral hemorrhage. Neurology. 2004;63(6):1059-1064
    • (2004) Neurology , vol.63 , Issue.6 , pp. 1059-1064
    • Flibotte, J.J.1    Hagan, N.2    O'Donnell J3    Greenberg, S.M.4    Rosand, J.5
  • 13
    • 1942437369 scopus 로고    scopus 로고
    • The effect of warfarin and intensity of anticoagulation on outcome of intracerebral hemorrhage
    • Rosand J, Eckman MH, Knudsen KA, Singer DE, Greenberg SM. The effect of warfarin and intensity of anticoagulation on outcome of intracerebral hemorrhage. Arch Intern Med. 2004; 164(8):880-884
    • (2004) Arch Intern Med , vol.164 , Issue.8 , pp. 880-884
    • Rosand, J.1    Eckman, M.H.2    Knudsen, K.A.3    Singer, D.E.4    Greenberg, S.M.5
  • 15
    • 0030933639 scopus 로고    scopus 로고
    • Emergency oral anticoagulant reversal: the relative efficacy of infusions of fresh frozen plasma and clotting factor concentrate on correction of the coagulopathy
    • Makris M, Greaves M, Phillips WS, Kitchen S, Rosendaal FR, Preston EF. Emergency oral anticoagulant reversal: the relative efficacy of infusions of fresh frozen plasma and clotting factor concentrate on correction of the coagulopathy. Thromb Haemost. 1997;77(3):477-480
    • (1997) Thromb Haemost , vol.77 , Issue.3 , pp. 477-480
    • Makris, M.1    Greaves, M.2    Phillips, W.S.3    Kitchen, S.4    Rosendaal, F.R.5    Preston, E.F.6
  • 16
    • 0031846573 scopus 로고    scopus 로고
    • Management of warfarin (coumarin) overdose
    • Baglin T. Management of warfarin (coumarin) overdose. Blood Rev. 1998;12(2):91-98
    • (1998) Blood Rev , vol.12 , Issue.2 , pp. 91-98
    • Baglin, T.1
  • 17
    • 0017114886 scopus 로고
    • Comparison of prothrombin complex concentrate and vitamin K1 in oral anticoagulant reversal
    • Taberner DA, Thomson JM, Poller L. Comparison of prothrombin complex concentrate and vitamin K1 in oral anticoagulant reversal. Br Med J. 1976;2(6027):83-85
    • (1976) Br Med J , vol.2 , Issue.6027 , pp. 83-85
    • Taberner, D.A.1    Thomson, J.M.2    Poller, L.3
  • 18
    • 38349096220 scopus 로고    scopus 로고
    • Role of prothrombin complex concentrates in reversing warfarin anticoagulation: A review of the literature
    • Leissinger CA, Blatt PM, Hoots WK, Ewenstein B. Role of prothrombin complex concentrates in reversing warfarin anticoagulation: a review of the literature. Am J Hematol. 2008;83(2): 137-143
    • (2008) Am J Hematol , vol.83 , Issue.2 , pp. 137-143
    • Leissinger, C.A.1    Blatt, P.M.2    Hoots, W.K.3    Ewenstein, B.4
  • 19
    • 45949103309 scopus 로고    scopus 로고
    • Pharmacology and management of the vitamin K antagonists: American college of chest physicians evidence-based clinical practice guidelines, 8th edition
    • Ansell J, Hirsh J, Hylek E, Jacobson A, Crowther M, Palareti G. Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines, 8th edition. Chest. 2008;133(6 Suppl):160S-98S.
    • (2008) Chest , vol.133 , Issue.6 SUPPL.
    • Ansell, J.1    Hirsh, J.2    Hylek, E.3    Jacobson, A.4    Crowther, M.5    Palareti, G.6
  • 20
    • 0033556414 scopus 로고    scopus 로고
    • Intravenous versus subcutaneous vitamin K1 in reversing excessive oral anticoagulation
    • A286-A287
    • Nee R, Doppenschmidt D, Donovan DJ, Andrews TC. Intravenous versus subcutaneous vitamin K1 in reversing excessive oral anticoagulation. Am J Cardiol. 1999, 83(2):286-288 (A286-287).
    • (1999) Am J Cardiol , vol.83 , Issue.2 , pp. 286-288
    • Nee, R.1    Doppenschmidt, D.2    Donovan, D.J.3    Andrews, T.C.4
  • 21
    • 0242592156 scopus 로고    scopus 로고
    • Comparison of oral vs intravenous phytonadione (vitamin K1) in patients with excessive anticoagulation: a prospective randomized controlled study
    • Lubetsky A, Yonath H, Olchovsky D, Loebstein R, Halkin H, Ezra D. Comparison of oral vs intravenous phytonadione (vitamin K1) in patients with excessive anticoagulation: a prospective randomized controlled study. Arch Intern Med. 2003;163(20): 2469-2473
    • (2003) Arch Intern Med , vol.163 , Issue.20 , pp. 2469-2473
    • Lubetsky, A.1    Yonath, H.2    Olchovsky, D.3    Loebstein, R.4    Halkin, H.5    Ezra, D.6
  • 22
    • 13844250594 scopus 로고    scopus 로고
    • Pharmacokinetics and efficacy of oral versus intravenous mixed-micellar phylloquinone (vitamin K1) in severe acute liver disease
    • Pereira SP, Rowbotham D, Fitt S, Shearer MJ, Wendon J, Williams R. Pharmacokinetics and efficacy of oral versus intravenous mixed-micellar phylloquinone (vitamin K1) in severe acute liver disease. J Hepatol. 2005;42(3):365-370
    • (2005) J Hepatol , vol.42 , Issue.3 , pp. 365-370
    • Pereira, S.P.1    Rowbotham, D.2    Fitt, S.3    Shearer, M.J.4    Wendon, J.5    Williams, R.6
  • 23
    • 33644862002 scopus 로고    scopus 로고
    • Guidelines on oral anticoagulation (warfarin): 3rd edition-2005 update
    • Baglin TP, Keeling DM, Watson HG. Guidelines on oral anticoagulation (warfarin): 3rd edition-2005 update. Br J Haematol. 2006;132(3):277-285
    • (2006) Br J Haematol , vol.132 , Issue.3 , pp. 277-285
    • Baglin, T.P.1    Keeling, D.M.2    Watson, H.G.3
  • 24
    • 43549087410 scopus 로고    scopus 로고
    • Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage
    • Mayer SA, Brun NC, Begtrup K, Broderick J, Davis S, Diringer MN, et al. Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage. N Engl J Med. 2008;358(20): 2127-2137
    • (2008) N Engl J Med , vol.358 , Issue.20 , pp. 2127-2137
    • Mayer, S.A.1    Brun, N.C.2    Begtrup, K.3    Broderick, J.4    Davis, S.5    Diringer, M.N.6
  • 26
    • 77955097218 scopus 로고    scopus 로고
    • rFVIIa in ICH in patients treated with anticoagulants or antiplatelets
    • rFVIIa in ICH in patients treated with anticoagulants or antiplatelets. www.clinicaltrials.gov.
  • 27
    • 35449007773 scopus 로고    scopus 로고
    • The headache over warfarin in British neurosurgical intensive care units: A national survey of current practice
    • Appelboam R, Thomas EO. The headache over warfarin in British neurosurgical intensive care units: a national survey of current practice. Intensive Care Med. 2007;33(11):1946-1953
    • (2007) Intensive Care Med , vol.33 , Issue.11 , pp. 1946-1953
    • Appelboam, R.1    Thomas, E.O.2
  • 28
    • 8844227509 scopus 로고    scopus 로고
    • Warfarin reversal: Consensus guidelines, on behalf of the Australasian society of thrombosis and haemostasis
    • Baker RI, Coughlin PB, Gallus AS, Harper PL, Salem HH, Wood EM. Warfarin reversal: consensus guidelines, on behalf of the Australasian Society of Thrombosis and Haemostasis. Med J Aust. 2004;181(9):492-497
    • (2004) Med J Aust , vol.181 , Issue.9 , pp. 492-497
    • Baker, R.I.1    Coughlin, P.B.2    Gallus, A.S.3    Harper, P.L.4    Salem, H.H.5    Wood, E.M.6
  • 29
    • 0014367269 scopus 로고
    • Management of Christmas disease and Stuart-Prower deficiency with a prothrombin-complex concentrate (factors II, VII, IX, X)
    • Tullis JL, Melin M. Management of Christmas disease and Stuart-Prower deficiency with a prothrombin-complex concentrate (factors II, VII, IX, X). Bibl Haematol. 1968;29:1134-1139
    • (1968) Bibl Haematol , vol.29 , pp. 1134-1139
    • Tullis, J.L.1    Melin, M.2
  • 30
    • 0015808279 scopus 로고
    • Prothrombin complex concentrates in acquired hypoprothrombinemia
    • Sandler SG, Rath CE, Ruder A. Prothrombin complex concentrates in acquired hypoprothrombinemia. Ann Intern Med. 1973;79(4):485-491
    • (1973) Ann Intern Med , vol.79 , Issue.4 , pp. 485-491
    • Sandler, S.G.1    Rath, C.E.2    Ruder, A.3
  • 31
    • 0034525056 scopus 로고    scopus 로고
    • Manufacturing of a prothrombin complex concentrate aiming at low thrombogenicity
    • Josic D, Hoffer L, Buchacher A, Schwinn H, Frenzel W, Biesert L, et al. Manufacturing of a prothrombin complex concentrate aiming at low thrombogenicity. Thromb Res. 2000;100(5):433-441
    • (2000) Thromb Res , vol.100 , Issue.5 , pp. 433-441
    • Josic, D.1    Hoffer, L.2    Buchacher, A.3    Schwinn, H.4    Frenzel, W.5    Biesert, L.6
  • 32
    • 0032822039 scopus 로고    scopus 로고
    • Production and composition of prothrombin complex concentrates: Correlation between composition and therapeutic efficiency
    • Hellstern P. Production and composition of prothrombin complex concentrates: correlation between composition and therapeutic efficiency. Thromb Res. 1999;95(4 Suppl 1):S7-12.
    • (1999) Thromb Res , vol.95 , Issue.4 SUPPL. 1
    • Hellstern, P.1
  • 34
    • 3042600900 scopus 로고    scopus 로고
    • Efficacy and safety of a prothrombin complex concentrate (Octaplex) for rapid reversal of oral anticoagulation
    • Lubetsky A, Hoffman R, Zimlichman R, Eldor A, Zvi J, Kostenko V, et al. Efficacy and safety of a prothrombin complex concentrate (Octaplex) for rapid reversal of oral anticoagulation. Thromb Res. 2004;113(6):371-378
    • (2004) Thromb Res , vol.113 , Issue.6 , pp. 371-378
    • Lubetsky, A.1    Hoffman, R.2    Zimlichman, R.3    Eldor, A.4    Zvi, J.5    Kostenko, V.6
  • 35
    • 0035676364 scopus 로고    scopus 로고
    • Beriplex P/N reverses severe warfarin-induced overanticoagulation immediately and completely in patients presenting with major bleeding
    • Evans G, Luddington R, Baglin T. Beriplex P/N reverses severe warfarin-induced overanticoagulation immediately and completely in patients presenting with major bleeding. Br J Haematol. 2001;115(4):998-1001.
    • (2001) Br J Haematol , vol.115 , Issue.4 , pp. 998-1001
    • Evans, G.1    Luddington, R.2    Baglin, T.3
  • 36
    • 35048885969 scopus 로고    scopus 로고
    • Pharmacokinetics of Beriplex P/N prothrombin complex concentrate in healthy volunteers
    • Ostermann H, Haertel S, Knaub S, Kalina U, Jung K, Pabinger I. Pharmacokinetics of Beriplex P/N prothrombin complex concentrate in healthy volunteers. Thromb Haemost. 2007;98(4):90-97
    • (2007) Thromb Haemost , vol.98 , Issue.4 , pp. 90-97
    • Ostermann, H.1    Haertel, S.2    Knaub, S.3    Kalina, U.4    Jung, K.5    Pabinger, I.6
  • 37
    • 0032703196 scopus 로고    scopus 로고
    • Use of factor IX complex in warfarin-related intracranial hemorrhage
    • discussion 1118-1119
    • Boulis NM, Bobek MP, Schmaier A, Hoff JT. Use of factor IX complex in warfarin-related intracranial hemorrhage. Neurosurgery. 1999;45(5):1113-8. discussion 1118-1119.
    • (1999) Neurosurgery , vol.45 , Issue.5 , pp. 1113-1118
    • Boulis, N.M.1    Bobek, M.P.2    Schmaier, A.3    Hoff, J.T.4
  • 38
    • 0033765008 scopus 로고    scopus 로고
    • Prothrombin complex concentrate for oral anticoagulant reversal in neurosurgicalemergencies
    • Cartmill M, Dolan G, Byrne JL, Byrne PO. Prothrombin complex concentrate for oral anticoagulant reversal in neurosurgicalemergencies. Br J Neurosurg. 2000;14(5):458-461
    • (2000) Br J Neurosurg , vol.14 , Issue.5 , pp. 458-461
    • Cartmill, M.1    Dolan, G.2    Byrne, J.L.3    Byrne, P.O.4
  • 39
    • 0026643411 scopus 로고
    • Emergency reversal of anticoagulation after intracerebral hemorrhage
    • Fredriksson K, Norrving B, Stromblad LG. Emergency reversal of anticoagulation after intracerebral hemorrhage. Stroke. 1992; 23(7):972-977
    • (1992) Stroke , vol.23 , Issue.7 , pp. 972-977
    • Fredriksson, K.1    Norrving, B.2    Stromblad, L.G.3
  • 41
    • 40949148098 scopus 로고    scopus 로고
    • Prothrombin complex concentrate (Beriplex P/N) for emergency anticoagulation reversal: A prospective multinational clinical trial
    • Pabinger I, Brenner B, Kalina U, Knaub S, Nagy A, Ostermann H. Prothrombin complex concentrate (Beriplex P/N) for emergency anticoagulation reversal: a prospective multinational clinical trial. J Thromb Haemost. 2008;6(4):622-631
    • (2008) J Thromb Haemost , vol.6 , Issue.4 , pp. 622-631
    • Pabinger, I.1    Brenner, B.2    Kalina, U.3    Knaub, S.4    Nagy, A.5    Ostermann, H.6
  • 42
    • 0036183415 scopus 로고    scopus 로고
    • Rapid reversal of oral anticoagulation with warfarin by a prothrombin complex concentrate (Beriplex): Efficacy and safety in 42 patients
    • Preston FE, Laidlaw ST, Sampson B, Kitchen S. Rapid reversal of oral anticoagulation with warfarin by a prothrombin complex concentrate (Beriplex): efficacy and safety in 42 patients. Br J Haematol. 2002;116(3):619-624
    • (2002) Br J Haematol , vol.116 , Issue.3 , pp. 619-624
    • Preston, F.E.1    Laidlaw, S.T.2    Sampson, B.3    Kitchen, S.4
  • 43
    • 33947523772 scopus 로고    scopus 로고
    • Ultra-rapid management of oral anticoagulant therapyrelated surgical intracranial hemorrhage
    • Vigue B, Ract C, Tremey B, Engrand N, Leblanc PE, Decaux A, et al. Ultra-rapid management of oral anticoagulant therapyrelated surgical intracranial hemorrhage. Intensive Care Med. 2007;33(4):721-725
    • (2007) Intensive Care Med , vol.33 , Issue.4 , pp. 721-725
    • Vigue, B.1    Ract, C.2    Tremey, B.3    Engrand, N.4    Leblanc, P.E.5    Decaux, A.6
  • 44
    • 0038014058 scopus 로고    scopus 로고
    • Effect of prothrombin complex concentrate on INR and blood coagulation system in emergency patients treated with warfarin overdose
    • Yasaka M, Oomura M, Ikeno K, Naritomi H, Minematsu K. Effect of prothrombin complex concentrate on INR and blood coagulation system in emergency patients treated with warfarin overdose. Ann Hematol. 2003;82(2):121-123
    • (2003) Ann Hematol , vol.82 , Issue.2 , pp. 121-123
    • Yasaka, M.1    Oomura, M.2    Ikeno, K.3    Naritomi, H.4    Minematsu, K.5
  • 45
    • 33746787177 scopus 로고    scopus 로고
    • Individualized dosing regimen for prothrombin complex concentrate more effective than standard treatment in the reversal of oral anticoagulant therapy: An open, prospective randomized controlled trial
    • van Aart L, Eijkhout HW, Kamphuis JS, Dam M, Schattenkerk ME, Schouten TJ, et al. Individualized dosing regimen for prothrombin complex concentrate more effective than standard treatment in the reversal of oral anticoagulant therapy: an open, prospective randomized controlled trial. Thromb Res. 2006; 118(3):313-320
    • (2006) Thromb Res , vol.118 , Issue.3 , pp. 313-320
    • Van Aart, L.1    Eijkhout, H.W.2    Kamphuis, J.S.3    Dam, M.4    Schattenkerk, M.E.5    Schouten, T.J.6
  • 46
    • 52449128017 scopus 로고    scopus 로고
    • Prothrombin complex concentrate (Beriplex P/N) in severe bleeding: experience in a large tertiary hospital
    • Bruce D, Nokes TJ. Prothrombin complex concentrate (Beriplex P/N) in severe bleeding: experience in a large tertiary hospital. Crit Care. 2008;12(4):R105.
    • (2008) Crit Care , vol.12 , Issue.4
    • Bruce, D.1    Nokes, T.J.2
  • 47
    • 15744371861 scopus 로고    scopus 로고
    • Optimal dose of prothrombin complex concentrate for acute reversal of oral anticoagulation
    • Yasaka M, Sakata T, Naritomi H, Minematsu K. Optimal dose of prothrombin complex concentrate for acute reversal of oral anticoagulation. Thromb Res. 2005;115(6):455-459
    • (2005) Thromb Res , vol.115 , Issue.6 , pp. 455-459
    • Yasaka, M.1    Sakata, T.2    Naritomi, H.3    Minematsu, K.4
  • 48
    • 0032847285 scopus 로고    scopus 로고
    • Prothrombin complex concentrates: Indications, contraindications, and risks: A task force summary
    • Hellstern P, Halbmayer WM, Kohler M, Seitz R, Muller-Berghaus G. Prothrombin complex concentrates: indications, contraindications, and risks: a task force summary. Thromb Res. 1999;95(4 Suppl 1):S3-6.
    • (1999) Thromb Res , vol.95 , Issue.4 SUPPL. 1
    • Hellstern, P.1    Halbmayer, W.M.2    Kohler, M.3    Seitz, R.4    Muller-Berghaus, G.5
  • 49
    • 33845327482 scopus 로고    scopus 로고
    • Anticoagulants and their reversal
    • Schulman S, Bijsterveld NR. Anticoagulants and their reversal. Transfus Med Rev. 2007;21(1):37-48.
    • (2007) Transfus Med Rev , vol.21 , Issue.1 , pp. 37-48
    • Schulman, S.1    Bijsterveld, N.R.2
  • 50
    • 0344898555 scopus 로고    scopus 로고
    • The use of prothrombin complex concentrates in the treatment of hemorrhages induced by oral anticoagulation
    • Pindur G, Morsdorf S. The use of prothrombin complex concentrates in the treatment of hemorrhages induced by oral anticoagulation. Thromb Res. 1999;95(4 Suppl 1):S57-61.
    • (1999) Thromb Res , vol.95 , Issue.4 SUPPL. 1
    • Pindur, G.1    Morsdorf, S.2
  • 51
    • 0034889092 scopus 로고    scopus 로고
    • The management of coumarin-induced over-anticoagulation Annotation
    • Makris M, Watson HG. The management of coumarin-induced over-anticoagulation Annotation. Br J Haematol. 2001;114(2): 271-280
    • (2001) Br J Haematol , vol.114 , Issue.2 , pp. 271-280
    • Makris, M.1    Watson, H.G.2
  • 52
    • 33645767960 scopus 로고    scopus 로고
    • Prothrombinex use for the reversal of warfarin, is fresh frozen plasma needed?
    • Crawford JH, Augustson BM. Prothrombinex use for the reversal of warfarin: is fresh frozen plasma needed? Med J Aust. 2006; 184(7):365-366
    • (2006) Med J Aust , vol.184 , Issue.7 , pp. 365-366
    • Crawford, J.H.1    Augustson, B.M.2
  • 53
    • 66549108216 scopus 로고    scopus 로고
    • Suboptimal effect of a three-factor prothrombin complex concentrate (Profilnine-SD) in correcting supratherapeutic international normalized ratio due to warfarin overdose
    • Holland L, Warkentin TE, Refaai M, Crowther MA, Johnston MA, Sarode R. Suboptimal effect of a three-factor prothrombin complex concentrate (Profilnine-SD) in correcting supratherapeutic international normalized ratio due to warfarin overdose. Transfusion. 2009;49(6):1171-1177
    • (2009) Transfusion , vol.49 , Issue.6 , pp. 1171-1177
    • Holland, L.1    Warkentin, T.E.2    Refaai, M.3    Crowther, M.A.4    Johnston, M.A.5    Sarode, R.6
  • 55
    • 0020476364 scopus 로고
    • Myocardial infarction complicating activated prothrombin complex concentrate substitution in patient with hemophilia A
    • Schimpf K, Zeltsch C, Zeltsch P. Myocardial infarction complicating activated prothrombin complex concentrate substitution in patient with hemophilia A. Lancet. 1982;2(8306):1043.
    • (1982) Lancet , vol.2 , Issue.8306 , pp. 1043
    • Schimpf, K.1    Zeltsch, C.2    Zeltsch, P.3
  • 56
    • 0027161439 scopus 로고
    • Reduced coagulation activation following infusion of a highly purified factor IX concentrate compared to a prothrombin complex concentrate
    • Hampton KK, Preston FE, Lowe GD, Walker ID, Sampson B. Reduced coagulation activation following infusion of a highly purified factor IX concentrate compared to a prothrombin complex concentrate. Br J Haematol. 1993;84(2):279-284
    • (1993) Br J Haematol , vol.84 , Issue.2 , pp. 279-284
    • Hampton, K.K.1    Preston, F.E.2    Lowe, G.D.3    Walker, I.D.4    Sampson, B.5
  • 58
    • 0025606932 scopus 로고
    • Comparison of different prothrombin complex concentrates-in vitro and in vivo studies
    • Kohler M, Heiden M, Harbauer G, Miyashita C, Morsdorf S, Braun B, et al. Comparison of different prothrombin complex concentrates-in vitro and in vivo studies. Thromb Res. 1990; 60(1):63-70.
    • (1990) Thromb Res , vol.60 , Issue.1 , pp. 63-70
    • Kohler, M.1    Heiden, M.2    Harbauer, G.3    Miyashita, C.4    Morsdorf, S.5    Braun, B.6
  • 59
    • 0030714126 scopus 로고    scopus 로고
    • Factor VII and activated-factor-VII content of prothrombin complex concentrates
    • The PCC Study Group
    • Hellstern P, Beeck H, Fellhauer A, Fischer A, Faller-Stockl B. Factor VII and activated-factor-VII content of prothrombin complex concentrates. The PCC Study Group. Vox Sang. 1997;73(3): 155-161
    • (1997) Vox Sang , vol.73 , Issue.3 , pp. 155-161
    • Hellstern, P.1    Beeck, H.2    Fellhauer, A.3    Fischer, A.4    Faller-Stockl, B.5
  • 60
    • 0344131428 scopus 로고    scopus 로고
    • Thrombogenicity of prothrombin complex concentrates
    • Kohler M. Thrombogenicity of prothrombin complex concentrates. Thromb Res. 1999;95(4 Suppl 1):S13-7.
    • (1999) Thromb Res , vol.95 , Issue.4 SUPPL. 1
    • Kohler, M.1
  • 61
    • 0017341861 scopus 로고
    • Prothrombin complex concentrates: Potentially thrombogenic materials and clues to the mechanism of thrombosis in vivo
    • WhiteGCII, Roberts HR, Kingdon HS, Lundblad RL. Prothrombin complex concentrates: potentially thrombogenic materials and clues to the mechanism of thrombosis in vivo. Blood. 1977;49(2): 159-170
    • (1977) Blood , vol.49 , Issue.2 , pp. 159-170
    • White II, G.C.1    Roberts, H.R.2    Kingdon, H.S.3    Lundblad, R.L.4
  • 62
    • 0028958843 scopus 로고
    • Measurement of activated factor IX in factor IX concentrates: Correlation with in vivo thrombogenicity
    • Gray E, Tubbs J, Thomas S, Oates A, Boisclair M, Kemball-Cook G, et al. Measurement of activated factor IX in factor IX concentrates: correlation with in vivo thrombogenicity. Thromb Haemost. 1995;73(4):675-679
    • (1995) Thromb Haemost , vol.73 , Issue.4 , pp. 675-679
    • Gray, E.1    Tubbs, J.2    Thomas, S.3    Oates, A.4    Boisclair, M.5    Kemball-Cook, G.6
  • 63
    • 0020056068 scopus 로고
    • The coagulant-active phospholipid content is a major determinant of in vivo thrombogenicity of prothrombin complex (Factor IX) concentrates in rabbits
    • Giles AR, Nesheim ME, Hoogendoorn H, Tracy PB, Mann KG. The coagulant-active phospholipid content is a major determinant of in vivo thrombogenicity of prothrombin complex (Factor IX) concentrates in rabbits. Blood. 1982;59(2):401-407
    • (1982) Blood , vol.59 , Issue.2 , pp. 401-407
    • Giles, A.R.1    Nesheim, M.E.2    Hoogendoorn, H.3    Tracy, P.B.4    Mann, K.G.5
  • 64
    • 0027232227 scopus 로고
    • Prediction and management of adverse events associated with the use of factor IX complex concentrates
    • Lusher JM. Prediction and management of adverse events associated with the use of factor IX complex concentrates. Semin Hematol. 1993;30(2 Suppl 1):36-40.
    • (1993) Semin Hematol , vol.30 , Issue.2 SUPPL 1 , pp. 36-40
    • Lusher, J.M.1
  • 65
    • 0032923432 scopus 로고    scopus 로고
    • Thrombosis and disseminated intravascular coagulation following treatment with the prothrombin complex concentrate DEFIX
    • Roddie PH, Stirling C, Mayne EE, Ludlam CA. Thrombosis and disseminated intravascular coagulation following treatment with the prothrombin complex concentrate, DEFIX. Thromb Haemost. 1999;81(4):667.
    • (1999) Thromb Haemost , vol.81 , Issue.4 , pp. 667
    • Roddie, P.H.1    Stirling, C.2    Mayne, E.E.3    Ludlam, C.A.4
  • 67
    • 0026042054 scopus 로고
    • Safety of vapour heated prothrombin complex concentrate (PCC) Prothromplex S-TIM 4
    • Preiss DU, Eberspacher B, Abdullah D, Rosner I. Safety of vapour heated prothrombin complex concentrate (PCC) Prothromplex S-TIM 4. Thromb Res. 1991;63(6):651-659
    • (1991) Thromb Res , vol.63 , Issue.6 , pp. 651-659
    • Preiss, D.U.1    Eberspacher, B.2    Abdullah, D.3    Rosner, I.4
  • 68
    • 0027326445 scopus 로고
    • Pharmacokinetics, thrombogenicity and safety of a doubletreated prothrombin complex concentrate
    • Morfini M, Longo G, Berntorp E, Cinotti S, Filimberti E, Messori A, et al. Pharmacokinetics, thrombogenicity and safety of a doubletreated prothrombin complex concentrate. Thromb Res. 1993; 71(3):175-184
    • (1993) Thromb Res , vol.71 , Issue.3 , pp. 175-184
    • Morfini, M.1    Longo, G.2    Berntorp, E.3    Cinotti, S.4    Filimberti, E.5    Messori, A.6
  • 69
    • 0026543642 scopus 로고
    • Solvent/detergent-treated plasma: A virus-inactivated substitute for fresh frozen plasma
    • Horowitz B, Bonomo R, Prince AM, Chin SN, Brotman B, Shulman RW. Solvent/detergent-treated plasma: a virus-inactivated substitute for fresh frozen plasma. Blood. 1992;79(3):826-831
    • (1992) Blood , vol.79 , Issue.3 , pp. 826-831
    • Horowitz, B.1    Bonomo, R.2    Prince, A.M.3    Chin, S.N.4    Brotman, B.5    Shulman, R.W.6
  • 70
    • 0032880763 scopus 로고    scopus 로고
    • Virus safety of prothrombin complex concentrates and factor IX concentrates
    • Seitz R, Dodt J. Virus safety of prothrombin complex concentrates and factor IX concentrates. Thromb Res. 1999;95(4 Suppl 1):S19-23.
    • (1999) Thromb Res , vol.95 , Issue.4 SUPPL 1
    • Seitz, R.1    Dodt, J.2
  • 71
    • 37849017372 scopus 로고    scopus 로고
    • Warfarin reversal with prothrombin complex concentrate confers better antifibrinolytic activity compared with recombinant activated factor VII
    • Taketomi T, Szlam F, Levy JH, Tanaka KA. Warfarin reversal with prothrombin complex concentrate confers better antifibrinolytic activity compared with recombinant activated factor VII. Blood Coagul Fibrinolysis. 2008;19(1):106-108
    • (2008) Blood Coagul Fibrinolysis , vol.19 , Issue.1 , pp. 106-108
    • Taketomi, T.1    Szlam, F.2    Levy, J.H.3    Tanaka, K.A.4
  • 72
    • 33847333963 scopus 로고    scopus 로고
    • Prothrombin complex concentrate versus recombinant factor VIIa for reversal of coumarin anticoagulation
    • Dickneite G. Prothrombin complex concentrate versus recombinant factor VIIa for reversal of coumarin anticoagulation. Thromb Res. 2007;119(5):643-651
    • (2007) Thromb Res , vol.119 , Issue.5 , pp. 643-651
    • Dickneite, G.1
  • 73
    • 33745141580 scopus 로고    scopus 로고
    • Hematoma growth and outcome in treated neurocritical care patients with intracerebral hemorrhage related to oral anticoagulant therapy: Comparison of acute treatment strategies using vitamin K, fresh frozen plasma, and prothrombin complex concentrates
    • Huttner HB, Schellinger PD, Hartmann M, Kohrmann M, Juettler E, Wikner J, et al. Hematoma growth and outcome in treated neurocritical care patients with intracerebral hemorrhage related to oral anticoagulant therapy: comparison of acute treatment strategies using vitamin K, fresh frozen plasma, and prothrombin complex concentrates. Stroke. 2006;37(6):1465-1470
    • (2006) Stroke , vol.37 , Issue.6 , pp. 1465-1470
    • Huttner, H.B.1    Schellinger, P.D.2    Hartmann, M.3    Kohrmann, M.4    Juettler, E.5    Wikner, J.6
  • 74
    • 66449108537 scopus 로고    scopus 로고
    • A protocol for the rapid normalization of INR in trauma patients with intracranial hemorrhage on prescribed warfarin therapy
    • Kalina M, Tinkoff G, Gbadebo A, Veneri P, Fulda G. A protocol for the rapid normalization of INR in trauma patients with intracranial hemorrhage on prescribed warfarin therapy. Am Surg. 2008;74(9):858-861
    • (2008) Am Surg , vol.74 , Issue.9 , pp. 858-861
    • Kalina, M.1    Tinkoff, G.2    Gbadebo, A.3    Veneri, P.4    Fulda, G.5
  • 75
    • 0032433374 scopus 로고    scopus 로고
    • Clinical experience with the use of clotting factor concentrates in oral anticoagulation reversal
    • 414-420
    • Nitu IC, Perry DJ, Lee CA. Clinical experience with the use of clotting factor concentrates in oral anticoagulation reversal. Clin Lab Haematol. 1998;20(6):363-7. 414-420
    • (1998) Clin Lab Haematol , vol.20 , Issue.6 , pp. 363-367
    • Nitu, I.C.1    Perry, D.J.2    Lee, C.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.