Free radical facilitated damage of ungual keratin

Free Radical Biology and Medicine

Volumn 49, Issue 5, 2010, Pages 865-871

  Khengar, Rajeshree H ^a   Brown, Marc B ^b,c   Turner, Rob B ^b   Traynor, Matthew J ^c   Holt, Katherine B ^d   Jones, Stuart A ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b MEDPHARM LTD   (United Kingdom)

^c UNIVERSITY OF HERTFORDSHIRE   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Disulfide; Nail; Onychomycosis; Redox; Thioglycolic acid; Ungual

Indexed keywords

FREE RADICAL; HYDROGEN PEROXIDE; KERATIN; THIOGLYCOLIC ACID; UREA;

ADSORPTION; ARTICLE; CONTROLLED STUDY; DIFFERENTIAL PULSE VOLTAMMETRY; DIMERIZATION; ELECTRODE; ELECTRON TRANSPORT; HUMAN; NAIL; OXIDATION REDUCTION REACTION; PERMEABILITY; PH MEASUREMENT; POTENTIOMETRY; PRIORITY JOURNAL; WATER TRANSPORT;

EID: 77955093407     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2010.06.013     Document Type: Article

References (28)

1. Gupchup G.V., Zatz J.L. Structural characteristics and permeability properties of the human nail: a review. J. Cosmet. Sci. 1999, 50:363-385.
2. Walters K.A., Flynn G.L., Marvel J.R. Physicochemical characterization of the human nail. 1. Pressure sealed apparatus for measuring nail plate permeabilities. J. Invest. Dermatol. 1981, 76:76-79.
3. Bulaj G. Formation of disulfide bonds in proteins and peptides. Biotechnol. Adv. 2005, 23:87-92.
4. Marshall R.C., Orwin D.F.G., Gillespie J.M. Structure and biochemistry of mammalian hard keratin. Electron Microsc. Rev. 1991, 4:47-83.
5. Creighton T.E. Disulfide bonds and protein stability. BioEssays 1988, 8:57-63.
6. Plaza S., Gruzinski R. Homogeneous and heterogeneous thermal decomposition of diphenyl disulphide. Wear 1996, 194:212-218.
7. McClements D.J., Dickinson E. Molecular basis of protein functionality. Advances in food colloids 1996, 27-76. Kluwer Academic, Dordrecht.
8. Murdan S. Drug delivery to the nail following topical application. Int. J. Pharm. 2002, 236:1-26.
9. Scher R.K., Baran R. Onychomycosis in clinical practice: factors contributing to recurrence. Br. J. Dermatol. 2003, 149:5-9.
10. Brown M.B., Khengar R.H., Turner R.B., Forbes B., Traynor M.J., Evans C.R.G., Jones S.A. Overcoming the nail barrier: a systematic investigation of ungual chemical penetration enhancement. Int. J. Pharm. 2009, 370:61-67.
11. Khengar R.H., Jones S.A., Turner R.B., Forbes B., Brown M.B. Nail swelling as a pre-formulation screen for the selection and optimisation of ungual penetration enhancers. Pharm. Res. 2007, 24:2207-2212.
12. Olsen E.A. Methods of hair removal. J. Am. Acad. Dermatol. 1999, 40:143-155.
13. Cannell D.W. Permanent waving and hair straightening. Clin. Dermatol. 1988, 6:71-82.
14. Robbins C.R. Chemical and physical behaviour of human hair 2002, Springer-Verlag, New York.
15. Marmer W.N., Dudley R.L. The oxidative degradation of keratin (wool and bovine hair). J. Am. Leather Chem. Assoc. 2006, 101:408-415.
16. Traynor M.J., Turner R.B., Evans C.R.G., Khengar R.H., Zhang L., Jones S.A., Brown M.B. A novel permeation enhancer designed to increase the permeation of currently marketed nail lacquers through human nail 2008, 11:90. Cardiff, UK, STS Publishing. K.R. Brain, K.A. Walters (Eds.).
17. Compton R.G., Saunders G.H.W. Electrode potentials 2002, Oxford Univ. Press, Oxford.
18. Maddock W.G., Coller F.A. The role of the extremities in the dissipation of heat. Am. J. Physiol. 1933, 106:589-596.
19. Lawrence J.N. Electrical resistance and tritiated water permeability as indicators of barrier integrity of in vitro human skin. Toxicol. in Vitro 1997, 11:241-249.
20. Cammen L.M. Use of liquid scintillation-counting of Cr-51 and C-14 in twin tracer method of measuring assimilation efficiency. Oecologia 1977, 30:249-251.
21. Capozzi G., Modena G. Oxidation of thiols. The chemistry of the thiol group 1974, 785-840. Wiley. S. Patai (Ed.).
22. Rieger P.H. Electrochemistry 1994, Springer, Dordrecht.
23. Bonini M.G., Augusto O. Carbon dioxide stimulates the production of thiyl, sulfinyl, and disulfide radical anion from thiol oxidation by peroxynitrite. J. Biol. Chem. 2001, 276:9749-9754.
24. Houk J., Singh R., Whitesides G.M. Measurement of thiol disulfide interchange reactions and thiol pka values. Methods Enzymol. 1987, 143:129-140.
25. Krishtalik L.I. pH-dependent redox potential: how to use it correctly in the activation energy analysis. Biochim. Biophys. Acta, Bioenerg. 2003, 1604:13-21.
26. Shahrokhian S., Yazdani J. Electrocatalytic oxidation of thioglycolic acid at carbon paste electrode modified with cobalt phthalocyanine: application as a potentiometric sensor. Electrochim. Acta 2003, 48:4143-4148.
27. Tan W.T., Bond A.M., Ngooi S.W., Lim E.B., Goh J.K. Electrochemical oxidation of L-cysteine mediated by a fullerene-C-60-modified carbon electrode. Anal. Chim. Acta 2003, 491:181-191.
28. Shahrokhian S., Hamzehloei A., Thaghani A., Mousavi S.R. Electrocatalytic oxidation of 2-thiouracil and 2-thiobarbituric acid at a carbon-paste electrode modified with cobalt phthalocyanine. Electroanalysis 2004, 16:915-921.