-
1
-
-
0027159063
-
Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung
-
Rusch V., Baselga J., Cordon-Cardo C., Orazem J., Zaman M., Hoda S., et al. Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung. Cancer Res 1993, 53:2379-2385.
-
(1993)
Cancer Res
, vol.53
, pp. 2379-2385
-
-
Rusch, V.1
Baselga, J.2
Cordon-Cardo, C.3
Orazem, J.4
Zaman, M.5
Hoda, S.6
-
2
-
-
0030297662
-
A comparison of epidermal growth factor receptor levels and other prognostic parameters in non-small cell lung cancer
-
Fujino S., Enokibori T., Tezuka N., Asada Y., Inoue S., Kato H., et al. A comparison of epidermal growth factor receptor levels and other prognostic parameters in non-small cell lung cancer. Eur J Cancer 1996, 32A:2070-2074.
-
(1996)
Eur J Cancer
, vol.32 A
, pp. 2070-2074
-
-
Fujino, S.1
Enokibori, T.2
Tezuka, N.3
Asada, Y.4
Inoue, S.5
Kato, H.6
-
3
-
-
33644845919
-
New approaches in the management of lung cancer
-
Kris M. New approaches in the management of lung cancer. J Natl Compr Canc Netw 2005, 3(Suppl. 1):S22-S24.
-
(2005)
J Natl Compr Canc Netw
, vol.3
, Issue.SUPPL. 1
-
-
Kris, M.1
-
4
-
-
0036569870
-
ZD1839, a selective oral epidermal growth factor receptor-tyrosine kinase inhibitor, is well tolerated and active in patients with solid, malignant tumors: results of a phase I trial
-
Ranson M., Hammond L.A., Ferry D., Kris M., Tullo A., Murray P.I., et al. ZD1839, a selective oral epidermal growth factor receptor-tyrosine kinase inhibitor, is well tolerated and active in patients with solid, malignant tumors: results of a phase I trial. J Clin Oncol 2002, 20:2240-2250.
-
(2002)
J Clin Oncol
, vol.20
, pp. 2240-2250
-
-
Ranson, M.1
Hammond, L.A.2
Ferry, D.3
Kris, M.4
Tullo, A.5
Murray, P.I.6
-
5
-
-
0036842170
-
Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types
-
Baselga J., Rischin D., Ranson M., Calvert H., Raymond E., Kieback D.G., et al. Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types. J Clin Oncol 2002, 20:4292-4302.
-
(2002)
J Clin Oncol
, vol.20
, pp. 4292-4302
-
-
Baselga, J.1
Rischin, D.2
Ranson, M.3
Calvert, H.4
Raymond, E.5
Kieback, D.G.6
-
6
-
-
65349116059
-
Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial
-
Pirker R., Pereira J.R., Szczesna A., Von Pawel J., Krzakowski M., Ramlau R., et al. Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial. Lancet 2009, 373:1525-1531.
-
(2009)
Lancet
, vol.373
, pp. 1525-1531
-
-
Pirker, R.1
Pereira, J.R.2
Szczesna, A.3
Von Pawel, J.4
Krzakowski, M.5
Ramlau, R.6
-
7
-
-
52049090365
-
Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21
-
Zhu C.Q., da Cunha S.G., Ding K., Sakurada A., Cutz J.C., Liu N., et al. Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21. J Clin Oncol 2008, 26:4268-4275.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4268-4275
-
-
Zhu, C.Q.1
da Cunha, S.G.2
Ding, K.3
Sakurada, A.4
Cutz, J.C.5
Liu, N.6
-
8
-
-
20444498630
-
Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer
-
Cappuzzo F., Hirsch F.R., Rossi E., Bartolini S., Ceresoli G.L., Bemis L., et al. Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer. J Natl Cancer Inst 2005, 97:643-655.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 643-655
-
-
Cappuzzo, F.1
Hirsch, F.R.2
Rossi, E.3
Bartolini, S.4
Ceresoli, G.L.5
Bemis, L.6
-
9
-
-
33947498978
-
Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer
-
Sequist L.V., Bell D.W., Lynch T.J., Haber D.A. Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer. J Clin Oncol 2007, 25:587-595.
-
(2007)
J Clin Oncol
, vol.25
, pp. 587-595
-
-
Sequist, L.V.1
Bell, D.W.2
Lynch, T.J.3
Haber, D.A.4
-
10
-
-
70349720358
-
Biomarker analyses from a phase III, randomized, open-label, first-line study of gefitinib (G) versus carboplatin/paclitaxel (C/P) in clinically selected patients (pts) with advanced non-small cell lung cancer (NSCLC) in Asia (IPASS)
-
[abstr.8006]
-
Fukuoka M., Wu Y., Thongprasert S., Yang C., Chu D., Saijo N., et al. Biomarker analyses from a phase III, randomized, open-label, first-line study of gefitinib (G) versus carboplatin/paclitaxel (C/P) in clinically selected patients (pts) with advanced non-small cell lung cancer (NSCLC) in Asia (IPASS). J Clin Oncol 2009, 27:15s. [abstr.8006].
-
(2009)
J Clin Oncol
, vol.27
-
-
Fukuoka, M.1
Wu, Y.2
Thongprasert, S.3
Yang, C.4
Chu, D.5
Saijo, N.6
-
11
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch T.J., Bell D.W., Sordella R., Gurubhagavatula S., Okimoto R.A., Brannigan B.W., et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004, 350:2129-2139.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
-
12
-
-
0037106377
-
Selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is generally well-tolerated and has activity in non-small-cell lung cancer and other solid tumors: results of a phase I trial
-
Herbst R.S., Maddox A.M., Rothenberg M.L., Small E.J., Rubin E.H., Baselga J., et al. Selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is generally well-tolerated and has activity in non-small-cell lung cancer and other solid tumors: results of a phase I trial. J Clin Oncol 2002, 20:3815-3825.
-
(2002)
J Clin Oncol
, vol.20
, pp. 3815-3825
-
-
Herbst, R.S.1
Maddox, A.M.2
Rothenberg, M.L.3
Small, E.J.4
Rubin, E.H.5
Baselga, J.6
-
13
-
-
0037673681
-
Phase I pharmacokinetic trial of the selective oral epidermal growth factor receptor tyrosine kinase inhibitor gefitinib ('Iressa', ZD1839) in Japanese patients with solid malignant tumors
-
Nakagawa K., Tamura T., Negoro S., Kudoh S., Yamamoto N., Yamamoto N., et al. Phase I pharmacokinetic trial of the selective oral epidermal growth factor receptor tyrosine kinase inhibitor gefitinib ('Iressa', ZD1839) in Japanese patients with solid malignant tumors. Ann Oncol 2003, 14:922-930.
-
(2003)
Ann Oncol
, vol.14
, pp. 922-930
-
-
Nakagawa, K.1
Tamura, T.2
Negoro, S.3
Kudoh, S.4
Yamamoto, N.5
Yamamoto, N.6
-
14
-
-
0036368423
-
ZD1839 (Iressa) in non-small cell lung cancer
-
Herbst R.S., Kies M.S. ZD1839 (Iressa) in non-small cell lung cancer. Oncologist 2002, 7(Suppl. 4):9-15.
-
(2002)
Oncologist
, vol.7
, Issue.SUPPL. 4
, pp. 9-15
-
-
Herbst, R.S.1
Kies, M.S.2
-
15
-
-
0012381722
-
Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected]
-
Fukuoka M., Yano S., Giaccone G., Tamura T., Nakagawa K., Douillard J.Y., et al. Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected]. J Clin Oncol 2003, 21:2237-2246.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2237-2246
-
-
Fukuoka, M.1
Yano, S.2
Giaccone, G.3
Tamura, T.4
Nakagawa, K.5
Douillard, J.Y.6
-
16
-
-
0142055937
-
Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial
-
Kris M.G., Natale R.B., Herbst R.S., Lynch T.J., Prager D., Belani C.P., et al. Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. JAMA 2003, 290:2149-2158.
-
(2003)
JAMA
, vol.290
, pp. 2149-2158
-
-
Kris, M.G.1
Natale, R.B.2
Herbst, R.S.3
Lynch, T.J.4
Prager, D.5
Belani, C.P.6
-
17
-
-
0037868167
-
Pilot trial of the epidermal growth factor receptor tyrosine kinase inhibitor gefitinib plus carboplatin and paclitaxel in patients with stage IIIB or IV non-small-cell lung cancer
-
Miller V.A., Johnson D.H., Krug L.M., Pizzo B., Tyson L., Perez W., et al. Pilot trial of the epidermal growth factor receptor tyrosine kinase inhibitor gefitinib plus carboplatin and paclitaxel in patients with stage IIIB or IV non-small-cell lung cancer. J Clin Oncol 2003, 21:2094-2100.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2094-2100
-
-
Miller, V.A.1
Johnson, D.H.2
Krug, L.M.3
Pizzo, B.4
Tyson, L.5
Perez, W.6
-
18
-
-
0034068319
-
Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor
-
Ciardiello F., Caputo R., Bianco R., Damiano V., Pomatico G., De Placido S., et al. Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor. Clin Cancer Res 2000, 6:2053-2063.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2053-2063
-
-
Ciardiello, F.1
Caputo, R.2
Bianco, R.3
Damiano, V.4
Pomatico, G.5
De Placido, S.6
-
19
-
-
1542503746
-
Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: a phase III trial-INTACT 1
-
Giaccone G., Herbst R.S., Manegold C., Scagliotti G., Rosell R., Miller V., et al. Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: a phase III trial-INTACT 1. J Clin Oncol 2004, 22:777-784.
-
(2004)
J Clin Oncol
, vol.22
, pp. 777-784
-
-
Giaccone, G.1
Herbst, R.S.2
Manegold, C.3
Scagliotti, G.4
Rosell, R.5
Miller, V.6
-
20
-
-
1542713370
-
Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: a phase III trial-INTACT 2
-
Herbst R.S., Giaccone G., Schiller J.H., Natale R.B., Miller V., Manegold C., et al. Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: a phase III trial-INTACT 2. J Clin Oncol 2004, 22:785-794.
-
(2004)
J Clin Oncol
, vol.22
, pp. 785-794
-
-
Herbst, R.S.1
Giaccone, G.2
Schiller, J.H.3
Natale, R.B.4
Miller, V.5
Manegold, C.6
-
21
-
-
77955096383
-
Combination effects of gefitinib plus cisplatin in non-small cell lung cancer (NSCLC): why have phase III trials failed?
-
[suppl.; abstr. 11022]
-
Tsai C., Chen T., Chazal K., Hsiao S. Combination effects of gefitinib plus cisplatin in non-small cell lung cancer (NSCLC): why have phase III trials failed?. J Clin Oncol 2009, 27:15s. [suppl.; abstr. 11022].
-
(2009)
J Clin Oncol
, vol.27
-
-
Tsai, C.1
Chen, T.2
Chazal, K.3
Hsiao, S.4
-
22
-
-
1542436704
-
Human tumor xenografts as predictive preclinical models for anticancer drug activity in humans: better than commonly perceived-but they can be improved
-
Kerbel R.S. Human tumor xenografts as predictive preclinical models for anticancer drug activity in humans: better than commonly perceived-but they can be improved. Cancer Biol Ther 2003, 2:S134-S139.
-
(2003)
Cancer Biol Ther
, vol.2
-
-
Kerbel, R.S.1
-
23
-
-
0024272364
-
Influence of organ environment on the growth, selection, and metastasis of human colon carcinoma cells in nude mice
-
Morikawa K., Walker S.M., Nakajima M., Pathak S., Jessup J.M., Fidler I.J. Influence of organ environment on the growth, selection, and metastasis of human colon carcinoma cells in nude mice. Cancer Res 1988, 48:6863-6871.
-
(1988)
Cancer Res
, vol.48
, pp. 6863-6871
-
-
Morikawa, K.1
Walker, S.M.2
Nakajima, M.3
Pathak, S.4
Jessup, J.M.5
Fidler, I.J.6
-
24
-
-
24944440830
-
TRIBUTE: a phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer
-
Herbst R.S., Prager D., Hermann R., Fehrenbacher L., Johnson B.E., Sandler A., et al. TRIBUTE: a phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer. J Clin Oncol 2005, 23:5892-5899.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5892-5899
-
-
Herbst, R.S.1
Prager, D.2
Hermann, R.3
Fehrenbacher, L.4
Johnson, B.E.5
Sandler, A.6
-
25
-
-
34248140107
-
Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-small-cell lung cancer: the Tarceva Lung Cancer Investigation Trial
-
Gatzemeier U., Pluzanska A., Szczesna A., Kaukel E., Roubec J., De Rosa F., et al. Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-small-cell lung cancer: the Tarceva Lung Cancer Investigation Trial. J Clin Oncol 2007, 25:1545-1552.
-
(2007)
J Clin Oncol
, vol.25
, pp. 1545-1552
-
-
Gatzemeier, U.1
Pluzanska, A.2
Szczesna, A.3
Kaukel, E.4
Roubec, J.5
De Rosa, F.6
-
26
-
-
22044445517
-
Erlotinib in previously treated non-small-cell lung cancer
-
Shepherd F.A., Rodrigues P.J., Ciuleanu T., Tan E.H., Hirsh V., Thongprasert S., et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005, 353:123-132.
-
(2005)
N Engl J Med
, vol.353
, pp. 123-132
-
-
Shepherd, F.A.1
Rodrigues, P.J.2
Ciuleanu, T.3
Tan, E.H.4
Hirsh, V.5
Thongprasert, S.6
-
27
-
-
27544503230
-
Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)
-
Thatcher N., Chang A., Parikh P., Rodrigues P.J., Ciuleanu T., Von Pawel J., et al. Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer). Lancet 2005, 366:1527-1537.
-
(2005)
Lancet
, vol.366
, pp. 1527-1537
-
-
Thatcher, N.1
Chang, A.2
Parikh, P.3
Rodrigues, P.J.4
Ciuleanu, T.5
Von Pawel, J.6
-
28
-
-
84867238929
-
®) as the second line therapy for the treatment of advanced non-small cell lung cancer patients: a randomized phase II trial
-
[abstr A2.6], WCLC 2009-13th world conference on lung cancer
-
®) as the second line therapy for the treatment of advanced non-small cell lung cancer patients: a randomized phase II trial. J Thorac Oncol 2009, [abstr A2.6].
-
(2009)
J Thorac Oncol
-
-
Uhm, J.E.1
Sun, J.M.2
Lee, S.H.3
Kong, J.H.4
Yun, J.A.5
Lee, S.M.6
-
29
-
-
2342624080
-
EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
-
Paez J.G., Janne P.A., Lee J.C., Tracy S., Greulich H., Gabriel S., et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004, 304:1497-1500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
-
30
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from " never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
-
Pao W., Miller V., Zakowski M., Doherty J., Politi K., Sarkaria I., et al. EGF receptor gene mutations are common in lung cancers from " never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA 2004, 101:13306-13311.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
Doherty, J.4
Politi, K.5
Sarkaria, I.6
-
31
-
-
56249109644
-
Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): a randomised phase III trial
-
Kim E.S., Hirsh V., Mok T., Socinski M.A., Gervais R., Wu Y.L., et al. Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): a randomised phase III trial. Lancet 2008, 372:1809-1818.
-
(2008)
Lancet
, vol.372
, pp. 1809-1818
-
-
Kim, E.S.1
Hirsh, V.2
Mok, T.3
Socinski, M.A.4
Gervais, R.5
Wu, Y.L.6
-
32
-
-
69949162760
-
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
-
Mok T.S., Wu Y.L., Thongprasert S., Yang C.H., Chu D.T., Saijo N., et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009, 361:947-957.
-
(2009)
N Engl J Med
, vol.361
, pp. 947-957
-
-
Mok, T.S.1
Wu, Y.L.2
Thongprasert, S.3
Yang, C.H.4
Chu, D.T.5
Saijo, N.6
-
33
-
-
61449455071
-
The prognostic and predictive role of histology in advanced non-small cell lung cancer: a literature review
-
Hirsch F.R., Spreafico A., Novello S., Wood M.D., Simms L., Papotti M. The prognostic and predictive role of histology in advanced non-small cell lung cancer: a literature review. J Thorac Oncol 2008, 3:1468-1481.
-
(2008)
J Thorac Oncol
, vol.3
, pp. 1468-1481
-
-
Hirsch, F.R.1
Spreafico, A.2
Novello, S.3
Wood, M.D.4
Simms, L.5
Papotti, M.6
-
34
-
-
70350493524
-
First-line gefitinib versus first-line chemotherapy by carboplatin (CBDCA) plus paclitaxel (TXL) in non-small cell lung cancer (NSCLC) patients (pts) with EGFR mutations: a phase III study (002) by North East Japan Gefitinib Study Group
-
[abstr. 8016]
-
Kobayashi K., Inoue A., Maemondo M., Sugawara H., Isobe H., Oizumi, et al. First-line gefitinib versus first-line chemotherapy by carboplatin (CBDCA) plus paclitaxel (TXL) in non-small cell lung cancer (NSCLC) patients (pts) with EGFR mutations: a phase III study (002) by North East Japan Gefitinib Study Group. J Clin Oncol 2009, 27:15s. [abstr. 8016].
-
(2009)
J Clin Oncol
, vol.27
-
-
Kobayashi, K.1
Inoue, A.2
Maemondo, M.3
Sugawara, H.4
Isobe, H.5
Oizumi6
-
35
-
-
75249087060
-
Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial
-
Mitsudomi T., Morita S., Yatabe Y., Negoro S., Okamoto I., Tsurutani J., et al. Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial. Lancet Oncol 2009.
-
(2009)
Lancet Oncol
-
-
Mitsudomi, T.1
Morita, S.2
Yatabe, Y.3
Negoro, S.4
Okamoto, I.5
Tsurutani, J.6
-
36
-
-
63049132774
-
First-line gefitinib for patients with advanced non-small-cell lung cancer harboring epidermal growth factor receptor mutations without indication for chemotherapy
-
Inoue A., Kobayashi K., Usui K., Maemondo M., Okinaga S., Mikami I., et al. First-line gefitinib for patients with advanced non-small-cell lung cancer harboring epidermal growth factor receptor mutations without indication for chemotherapy. J Clin Oncol 2009, 27:1394-1400.
-
(2009)
J Clin Oncol
, vol.27
, pp. 1394-1400
-
-
Inoue, A.1
Kobayashi, K.2
Usui, K.3
Maemondo, M.4
Okinaga, S.5
Mikami, I.6
-
37
-
-
4344646459
-
Determinants of tumor response and survival with erlotinib in patients with non-small-cell lung cancer
-
Perez-Soler R., Chachoua A., Hammond L.A., Rowinsky E.K., Huberman M., Karp D., et al. Determinants of tumor response and survival with erlotinib in patients with non-small-cell lung cancer. J Clin Oncol 2004, 22:3238-3247.
-
(2004)
J Clin Oncol
, vol.22
, pp. 3238-3247
-
-
Perez-Soler, R.1
Chachoua, A.2
Hammond, L.A.3
Rowinsky, E.K.4
Huberman, M.5
Karp, D.6
-
38
-
-
33645805630
-
Use of cigarette-smoking history to estimate the likelihood of mutations in epidermal growth factor receptor gene exons 19 and 21 in lung adenocarcinomas
-
Pham D., Kris M.G., Riely G.J., Sarkaria I.S., McDonough T., Chuai S., et al. Use of cigarette-smoking history to estimate the likelihood of mutations in epidermal growth factor receptor gene exons 19 and 21 in lung adenocarcinomas. J Clin Oncol 2006, 24:1700-1704.
-
(2006)
J Clin Oncol
, vol.24
, pp. 1700-1704
-
-
Pham, D.1
Kris, M.G.2
Riely, G.J.3
Sarkaria, I.S.4
McDonough, T.5
Chuai, S.6
-
39
-
-
33846456433
-
Prospective trial with preoperative gefitinib to correlate lung cancer response with EGFR exon 19 and 21 mutations and to select patients for adjuvant therapy
-
ASCO annual meeting proceedings: part I.
-
Kris M., Pao W., Zakowski M., Ladanyi M., Heelan R., Schwartz, et al. Prospective trial with preoperative gefitinib to correlate lung cancer response with EGFR exon 19 and 21 mutations and to select patients for adjuvant therapy. J Clin Oncol 2006, 7021.
-
(2006)
J Clin Oncol
, vol.24
, Issue.18 S
, pp. 7021
-
-
Kris, M.1
Pao, W.2
Zakowski, M.3
Ladanyi, M.4
Heelan, R.5
Schwartz6
-
40
-
-
70249092148
-
EGFR mutation analysis in non-small-cell lung cancer: experience from routine diagnostics
-
Tapia C., Savic S., Bihl M., Rufle A., Zlobec I., Terracciano L., et al. EGFR mutation analysis in non-small-cell lung cancer: experience from routine diagnostics. Pathology 2009.
-
(2009)
Pathology
-
-
Tapia, C.1
Savic, S.2
Bihl, M.3
Rufle, A.4
Zlobec, I.5
Terracciano, L.6
-
41
-
-
45149084723
-
First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations
-
Sequist L.V., Martins R.G., Spigel D., Grunberg S.M., Spira A., Janne P.A., et al. First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations. J Clin Oncol 2008, 26:2442-2449.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2442-2449
-
-
Sequist, L.V.1
Martins, R.G.2
Spigel, D.3
Grunberg, S.M.4
Spira, A.5
Janne, P.A.6
-
42
-
-
34548182258
-
Mucinous differentiation correlates with absence of EGFR mutation and presence of KRAS mutation in lung adenocarcinomas with bronchioloalveolar features
-
Finberg K.E., Sequist L.V., Joshi V.A., Muzikansky A., Miller J.M., Han M., et al. Mucinous differentiation correlates with absence of EGFR mutation and presence of KRAS mutation in lung adenocarcinomas with bronchioloalveolar features. J Mol Diagn 2007, 9:320-326.
-
(2007)
J Mol Diagn
, vol.9
, pp. 320-326
-
-
Finberg, K.E.1
Sequist, L.V.2
Joshi, V.A.3
Muzikansky, A.4
Miller, J.M.5
Han, M.6
-
43
-
-
33645163460
-
A correlation between EGFR gene mutation status and bronchioloalveolar carcinoma features in Japanese patients with adenocarcinoma
-
Haneda H., Sasaki H., Lindeman N., Kawano O., Endo K., Suzuki E., et al. A correlation between EGFR gene mutation status and bronchioloalveolar carcinoma features in Japanese patients with adenocarcinoma. Jpn J Clin Oncol 2006, 36:69-75.
-
(2006)
Jpn J Clin Oncol
, vol.36
, pp. 69-75
-
-
Haneda, H.1
Sasaki, H.2
Lindeman, N.3
Kawano, O.4
Endo, K.5
Suzuki, E.6
-
44
-
-
33749023855
-
Epidermal growth factor receptor mutation in lung cancer are linked to bronchioloalveolar differentiation
-
Blons H., Cote J.F., Le Corre D., Riquet M., Fabre-Guilevin E., Laurent-Puig P., et al. Epidermal growth factor receptor mutation in lung cancer are linked to bronchioloalveolar differentiation. Am J Surg Pathol 2006, 30:1309-1315.
-
(2006)
Am J Surg Pathol
, vol.30
, pp. 1309-1315
-
-
Blons, H.1
Cote, J.F.2
Le Corre, D.3
Riquet, M.4
Fabre-Guilevin, E.5
Laurent-Puig, P.6
-
45
-
-
33644746049
-
Epidermal growth factor receptor gene mutation defines distinct subsets among small adenocarcinomas of the lung
-
Haneda H., Sasaki H., Shimizu S., Endo K., Suzuki E., Yukiue H., et al. Epidermal growth factor receptor gene mutation defines distinct subsets among small adenocarcinomas of the lung. Lung Cancer 2006, 52:47-52.
-
(2006)
Lung Cancer
, vol.52
, pp. 47-52
-
-
Haneda, H.1
Sasaki, H.2
Shimizu, S.3
Endo, K.4
Suzuki, E.5
Yukiue, H.6
-
46
-
-
69949186250
-
Screening for epidermal growth factor receptor mutations in lung cancer
-
Rosell R., Moran T., Queralt C., Porta R., Cardenal F., Camps C., et al. Screening for epidermal growth factor receptor mutations in lung cancer. N Engl J Med 2009, 361:958-967.
-
(2009)
N Engl J Med
, vol.361
, pp. 958-967
-
-
Rosell, R.1
Moran, T.2
Queralt, C.3
Porta, R.4
Cardenal, F.5
Camps, C.6
-
47
-
-
37549002543
-
Isolation of rare circulating tumour cells in cancer patients by microchip technology
-
Nagrath S., Sequist L.V., Maheswaran S., Bell D.W., Irimia D., Ulkus L., et al. Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature 2007, 450:1235-1239.
-
(2007)
Nature
, vol.450
, pp. 1235-1239
-
-
Nagrath, S.1
Sequist, L.V.2
Maheswaran, S.3
Bell, D.W.4
Irimia, D.5
Ulkus, L.6
-
48
-
-
65349161510
-
EGFR testing in lung cancer is ready for prime time
-
Hirsch F.R., Bunn P.A. EGFR testing in lung cancer is ready for prime time. Lancet Oncol 2009, 10:432-433.
-
(2009)
Lancet Oncol
, vol.10
, pp. 432-433
-
-
Hirsch, F.R.1
Bunn, P.A.2
-
49
-
-
68049088934
-
EGFR/KRAS/BRAF mutations in primary lung adenocarcinomas and corresponding locoregional lymph node metastases
-
Schmid K., Oehl N., Wrba F., Pirker R., Pirker C., Filipits M. EGFR/KRAS/BRAF mutations in primary lung adenocarcinomas and corresponding locoregional lymph node metastases. Clin Cancer Res 2009, 15:4554-4560.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4554-4560
-
-
Schmid, K.1
Oehl, N.2
Wrba, F.3
Pirker, R.4
Pirker, C.5
Filipits, M.6
-
50
-
-
45149086387
-
Non-small-cell lung cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up
-
D'Addario G., Felip E. Non-small-cell lung cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann Oncol 2008, 19(Suppl. 2):ii39-ii40.
-
(2008)
Ann Oncol
, vol.19
, Issue.SUPPL. 2
-
-
D'Addario, G.1
Felip, E.2
-
51
-
-
20044364940
-
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
-
Shigematsu H., Lin L., Takahashi T., Nomura M., Suzuki M., Wistuba I.I., et al. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst 2005, 97:339-346.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 339-346
-
-
Shigematsu, H.1
Lin, L.2
Takahashi, T.3
Nomura, M.4
Suzuki, M.5
Wistuba, I.I.6
-
52
-
-
28844449401
-
Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: molecular analysis of the IDEAL/INTACT gefitinib trials
-
Bell D.W., Lynch T.J., Haserlat S.M., Harris P.L., Okimoto R.A., Brannigan B.W., et al. Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: molecular analysis of the IDEAL/INTACT gefitinib trials. J Clin Oncol 2005, 23:8081-8092.
-
(2005)
J Clin Oncol
, vol.23
, pp. 8081-8092
-
-
Bell, D.W.1
Lynch, T.J.2
Haserlat, S.M.3
Harris, P.L.4
Okimoto, R.A.5
Brannigan, B.W.6
-
53
-
-
74749092577
-
Multicenter prospective trial of customized erlotinib for advanced non-small cell lung cancer (NSCLC) patients (p) with epidermal growth factor receptor (EGFR) mutations: final results of the Spanish Lung Cancer Group (SLCG) trial
-
[abstr. 8023]
-
Massuti B., Moran T., Porta R., Queralt C., Cardenal F., Mayo C., et al. Multicenter prospective trial of customized erlotinib for advanced non-small cell lung cancer (NSCLC) patients (p) with epidermal growth factor receptor (EGFR) mutations: final results of the Spanish Lung Cancer Group (SLCG) trial. J Clin Oncol 2009, 27(Suppl.):15s. [abstr. 8023].
-
(2009)
J Clin Oncol
, vol.27
, Issue.SUPPL.
-
-
Massuti, B.1
Moran, T.2
Porta, R.3
Queralt, C.4
Cardenal, F.5
Mayo, C.6
-
54
-
-
77955097019
-
Recent issues in first-line treatment of advanced non-small-cell lung cancer: results of an International Expert Panel Meeting of the Italian Association of Thoracic Oncology
-
Gridelli C., Ardizzoni A., Douillard J.Y., Hanna N., Manegold C., Perrone F., et al. Recent issues in first-line treatment of advanced non-small-cell lung cancer: results of an International Expert Panel Meeting of the Italian Association of Thoracic Oncology. Lung Cancer 2009.
-
(2009)
Lung Cancer
-
-
Gridelli, C.1
Ardizzoni, A.2
Douillard, J.Y.3
Hanna, N.4
Manegold, C.5
Perrone, F.6
-
55
-
-
37049183697
-
Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon D.J., Clark G.M., Wong S.G., Levin W.J., Ullrich A., McGuire W.L. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987, 235:177-182.
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
Levin, W.J.4
Ullrich, A.5
McGuire, W.L.6
-
56
-
-
2142758687
-
HER-2 testing in breast cancer using parallel tissue-based methods
-
Yaziji H., Goldstein L.C., Barry T.S., Werling R., Hwang H., Ellis G.K., et al. HER-2 testing in breast cancer using parallel tissue-based methods. JAMA 2004, 291:1972-1977.
-
(2004)
JAMA
, vol.291
, pp. 1972-1977
-
-
Yaziji, H.1
Goldstein, L.C.2
Barry, T.S.3
Werling, R.4
Hwang, H.5
Ellis, G.K.6
-
57
-
-
3042622482
-
HER2 amplification ratios by fluorescence in situ hybridization and correlation with immunohistochemistry in a cohort of 6556 breast cancer tissues
-
Owens M.A., Horten B.C., Da Silva M.M. HER2 amplification ratios by fluorescence in situ hybridization and correlation with immunohistochemistry in a cohort of 6556 breast cancer tissues. Clin Breast Cancer 2004, 5:63-69.
-
(2004)
Clin Breast Cancer
, vol.5
, pp. 63-69
-
-
Owens, M.A.1
Horten, B.C.2
Da Silva, M.M.3
-
58
-
-
41149140325
-
Pharmacogenetic profiling for cetuximab plus irinotecan therapy in patients with refractory advanced colorectal cancer
-
Graziano F., Ruzzo A., Loupakis F., Canestrari E., Santini D., Catalano V., et al. Pharmacogenetic profiling for cetuximab plus irinotecan therapy in patients with refractory advanced colorectal cancer. J Clin Oncol 2008, 26:1427-1434.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1427-1434
-
-
Graziano, F.1
Ruzzo, A.2
Loupakis, F.3
Canestrari, E.4
Santini, D.5
Catalano, V.6
-
59
-
-
51049092984
-
K-Ras mutations and treatment outcome in colorectal cancer patients receiving exclusive fluoropyrimidine therapy
-
Etienne-Grimaldi M.C., Formento J.L., Francoual M., Francois E., Formento P., Renee N., et al. K-Ras mutations and treatment outcome in colorectal cancer patients receiving exclusive fluoropyrimidine therapy. Clin Cancer Res 2008, 14:4830-4835.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4830-4835
-
-
Etienne-Grimaldi, M.C.1
Formento, J.L.2
Francoual, M.3
Francois, E.4
Formento, P.5
Renee, N.6
-
60
-
-
33746789922
-
Prospective phase II study of gefitinib for chemotherapy-naive patients with advanced non-small-cell lung cancer with epidermal growth factor receptor gene mutations
-
Inoue A., Suzuki T., Fukuhara T., Maemondo M., Kimura Y., Morikawa N., et al. Prospective phase II study of gefitinib for chemotherapy-naive patients with advanced non-small-cell lung cancer with epidermal growth factor receptor gene mutations. J Clin Oncol 2006, 24:3340-3346.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3340-3346
-
-
Inoue, A.1
Suzuki, T.2
Fukuhara, T.3
Maemondo, M.4
Kimura, Y.5
Morikawa, N.6
-
61
-
-
34247241615
-
EGFR mutation-based phase II multicenter trial of gefitinib in advanced non-small cell lung cancer (NSCLC) patients (pts): results of West Japan Thoracic Oncology Group trial (WJTOG0403)
-
ASCO annual meeting proceedings: part I.
-
Okamoto I., Kashii T., Urata T., Hirashima T., Kudoh S., Ichinose Y., et al. EGFR mutation-based phase II multicenter trial of gefitinib in advanced non-small cell lung cancer (NSCLC) patients (pts): results of West Japan Thoracic Oncology Group trial (WJTOG0403). J Clin Oncol 2006, 7073.
-
(2006)
J Clin Oncol
, vol.24
, Issue.18 S
, pp. 7073
-
-
Okamoto, I.1
Kashii, T.2
Urata, T.3
Hirashima, T.4
Kudoh, S.5
Ichinose, Y.6
-
62
-
-
34249986515
-
Phase II study of gefitinib for non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) gene mutations detected by PNA-LNA PCR clamp
-
ASCO annual meeting proceedings: part I.
-
Sutani A., Nagai Y., Udagawa K., Uchida Y., Murayama Y., Tanaka T., et al. Phase II study of gefitinib for non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) gene mutations detected by PNA-LNA PCR clamp. J Clin Oncol 2006, 7076.
-
(2006)
J Clin Oncol
, vol.24
, Issue.18 S
, pp. 7076
-
-
Sutani, A.1
Nagai, Y.2
Udagawa, K.3
Uchida, Y.4
Murayama, Y.5
Tanaka, T.6
-
63
-
-
33846702438
-
Prospective analysis of the epidermal growth factor receptor gene mutations in non-small cell lung cancer in Japan
-
ASCO annual meeting proceedings: part I.
-
Morikawa K., Inoue A., Suzuki M., Fukuhara T., Suzuki S., Kondo, et al. Prospective analysis of the epidermal growth factor receptor gene mutations in non-small cell lung cancer in Japan. J Clin Oncol 2006, 7077.
-
(2006)
J Clin Oncol
, vol.24
, Issue.18 S
, pp. 7077
-
-
Morikawa, K.1
Inoue, A.2
Suzuki, M.3
Fukuhara, T.4
Suzuki, S.5
Kondo6
-
64
-
-
34249752278
-
Prospective validation for prediction of gefitinib sensitivity by epidermal growth factor receptor gene mutation in patients with non-small cell lung cancer
-
Yoshida K., Yatabe Y., Park J.Y., Shimizu J., Horio Y., Matsuo K., et al. Prospective validation for prediction of gefitinib sensitivity by epidermal growth factor receptor gene mutation in patients with non-small cell lung cancer. J Thorac Oncol 2007, 2:22-28.
-
(2007)
J Thorac Oncol
, vol.2
, pp. 22-28
-
-
Yoshida, K.1
Yatabe, Y.2
Park, J.Y.3
Shimizu, J.4
Horio, Y.5
Matsuo, K.6
-
65
-
-
34247619676
-
Phase II prospective study of the efficacy of gefitinib for the treatment of stage III/IV non-small cell lung cancer with EGFR mutations, irrespective of previous chemotherapy
-
Sunaga N., Tomizawa Y., Yanagitani N., Iijima H., Kaira K., Shimizu K., et al. Phase II prospective study of the efficacy of gefitinib for the treatment of stage III/IV non-small cell lung cancer with EGFR mutations, irrespective of previous chemotherapy. Lung Cancer 2007, 56:383-389.
-
(2007)
Lung Cancer
, vol.56
, pp. 383-389
-
-
Sunaga, N.1
Tomizawa, Y.2
Yanagitani, N.3
Iijima, H.4
Kaira, K.5
Shimizu, K.6
-
66
-
-
41149097557
-
Molecular characteristics of bronchioloalveolar carcinoma and adenocarcinoma, bronchioloalveolar carcinoma subtype, predict response to erlotinib
-
Miller V.A., Riely G.J., Zakowski M.F., Li A.R., Patel J.D., Heelan R.T., et al. Molecular characteristics of bronchioloalveolar carcinoma and adenocarcinoma, bronchioloalveolar carcinoma subtype, predict response to erlotinib. J Clin Oncol 2008, 26:1472-1478.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1472-1478
-
-
Miller, V.A.1
Riely, G.J.2
Zakowski, M.F.3
Li, A.R.4
Patel, J.D.5
Heelan, R.T.6
-
67
-
-
72449160988
-
A randomized phase III study of gefitinib (IRESSATM) versus standard chemotherapy (gemcitabine plus cisplatin) as a first-line treatment for never-smokers with advanced or metastatic adenocarcinoma of the lung
-
[abstr. PRS.4], WCLC 2009-13th world conference on lung cancer
-
Lee J.S., Park K., Kim S.W., Lee D.H., Kim H.T., Han J.Y., et al. A randomized phase III study of gefitinib (IRESSATM) versus standard chemotherapy (gemcitabine plus cisplatin) as a first-line treatment for never-smokers with advanced or metastatic adenocarcinoma of the lung. J Thorac Oncol 2009, [abstr. PRS.4].
-
(2009)
J Thorac Oncol
-
-
Lee, J.S.1
Park, K.2
Kim, S.W.3
Lee, D.H.4
Kim, H.T.5
Han, J.Y.6
|