Comparison of two different local anaesthetic infiltrations for postoperative pain relief in tonsillectomy: A prospective, randomised, double blind, clinical trial

European Archives of Oto-Rhino-Laryngology

Volumn 267, Issue 7, 2010, Pages 1129-1134

  Stelter, Klaus ^a   Hiller, Joachim ^a   Hempel, John Martin ^a   Berghau, Alexander ^a   Hagedorn, Hjalmar ^b   Andratschke, Michaela ^b   Canis, Martin ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b Medical Centre Dachau   (Germany)

Author keywords

Bupivacaine; Clinical trial; Double blind; Epinephrine; Hemorrhage; Infiltration; Interindividual; Intraindividual; Local anaesthetic; Mepivacaine; New study design; Pain; Pain management; Randomized; Tonsillectomy; VAS

Indexed keywords

ADRENALIN; ANALGESIC AGENT; BUPIVACAINE; CEFUROXIME; DIPYRONE; IBUPROFEN; MEPIVACAINE; PARACETAMOL; PETHIDINE; PIRITRAMIDE; PROMETHAZINE; PROPOFOL; REMIFENTANIL; STEROID; SUFENTANIL;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CHRONIC TONSILLITIS; CLINICAL ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONNECTIVE TISSUE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DOUBLE BLIND PROCEDURE; DYSPHAGIA; EDEMA; FEMALE; HUMAN; LOCAL ANESTHESIA; MALE; MOUTH EDEMA; NOCICEPTION; NURSING STAFF; OTALGIA; PAIN ASSESSMENT; POSTOPERATIVE ANALGESIA; POSTOPERATIVE HEMORRHAGE; POSTOPERATIVE PAIN; POSTOPERATIVE PERIOD; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; SINUS TACHYCARDIA; SUPERINFECTION; SWALLOWING; TACHYCARDIA; TONGUE HYPESTHESIA; TONSILLECTOMY; VISUAL ANALOG SCALE;

ADOLESCENT; ADULT; AGED; ANALGESICS; ANESTHESIA, LOCAL; ANESTHETICS, LOCAL; BUPIVACAINE; CHILD; DEGLUTITION; DOUBLE-BLIND METHOD; EPINEPHRINE; FEMALE; HUMANS; INSTILLATION, DRUG; MALE; MEPIVACAINE; MIDDLE AGED; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; PROSPECTIVE STUDIES; TONSILLECTOMY; TREATMENT OUTCOME;

EID: 77955092645     PISSN: 09374477     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00405-009-1200-8     Document Type: Article

References (32)

1. Dal D, Celebi N, Elvan EG, Celiker V, Aypar U (2007) The efficacy of intravenous or peritonsillar infiltration of ketamine for postoperative pain relief in children following adenotonsillectomy. Paediatr Anaesth 17(3):263-269.
2. Freeman SB, Markwell JK (1992) Sucralfate in alleviating posttonsillectomy pain. Laryngoscope 102(11):1242-1246.
3. Goldsher M, Podoshin L, Fradis M et al (1996) Effects of peritonsillar infiltration on post-tonsillectomy pain. A double-blind study. Ann Otol Rhinol Laryngol 105(11):868-870.
4. Nordahl SH, Albrektsen G, Guttormsen AB, Pedersen IL, Breidablikk HJ (1999) Effect of bupivacaine on pain after tonsillectomy: a randomized clinical trial. Acta Otolaryngol 119(3):369-376.
5. Orntoft S, Longreen A, Moiniche S, Dhal JB (1994) A comparison of pre- and postoperative tonsillar infiltration with bupivacaine on pain after tonsillectomy. A pre-emptive effect? Anaesthesia 49(2):151-154.
6. Johansen M, Harbo G, Illum P (1996) Preincisional infiltration with bupivacaine in tonsillectomy. Arch Otolaryngol Head Neck Surg 122(3):261-263.
7. Knudsen KE, Brofeldt S, Mikkelsen S, Bille M, Brennum J, Dahl JB (1995) Peritonsillar infiltration with low-dose tenoxicam after tonsillectomy. Br J Anaesth 75(3):286-288.
8. Jebeles JA, Reilly JS, Gutierrez JF, Bradley EL Jr, Kissin I (1991) The effect of pre-incisional infiltration of tonsils with bupivacaine on the pain following tonsillectomy under general anesthesia. Pain 47(3):305-308.
9. Hollis LJ, Burton MJ, Millar JM (2000) Perioperative local anaesthesia for reducing pain following tonsillectomy. Cochrane Database Syst Rev (2):CD001874.
10. Grainger J, Saravanappa N (2008) Local anaesthetic for posttonsillectomy pain: a systematic review and meta-analysis. Clin Otolaryngol 33(5):411-419.
11. Sorensen WT, Wagner N, Aarup AT, Bonding P (2003) Beneficial effect of low-dose peritonsillar injection of lidocaine-adrenaline before tonsillectomy. A placebo-controlled clinical trial. Auris Nasus Larynx 30(2):159-162.
12. Stelter K, Hempel JM, Berghaus A, Andratschke M, Luebbers CW, Hagedorn H (2009) Application methods of local anaesthetic inWltrations for postoperative pain relief in tonsillectomy: a prospective, randomised, double-blind, clinical trial. Eur Arch Otorhinolaryngol 266(10):1615-1620.
13. Nolte H, Puente-Egido JJ (1969) The new local anesthetic bupivacaine (carbostesin) in clinical use. Anaesthesist 18(8):264-265.
14. Arikan OK, Ozcan S, Kazkayasi M, Akpinar S, Koc C (2006) Preincisional infiltration of tonsils with ropivacaine in post-tonsillectomy pain relief: double-blind, randomized, placebo-controlled intraindividual study. J Otolaryngol 35(3):167-172.
15. Holt GR, Watkins TM, Yoder MG, Garcia A (1981) The effect of tonsillectomy on impedance audiometry. Otolaryngol Head Neck Surg 89(1):20-26.
16. Warnock FF, Lander J (1998) Pain progression, intensity and outcomes following tonsillectomy. Pain 75(1):37-45.
17. Williamson A, Hoggart B (2005) Pain: a review of three commonly used pain rating scales. J Clin Nurs 14(7):798-804.
18. Finley GA, McGrath PJ (1996) Postoperative pain in children. Can J Anaesth 43(4):418-419.
19. Sloman R, Wruble AW, Rosen G, Rom M (2006) Determination of clinically meaningful levels of pain reduction in patients experiencing acute postoperative pain. Pain Manag Nurs 7(4):153-158.
20. Pasero C, McCaffery M (2005) No self-report means no painintensity rating. Am J Nurs 105(10):50-53.
21. Somdas MA, Senturk M, Ketenci I, Erkorkmaz U, Unlu Y (2004) Efficacy of bupivacaine for post-tonsillectomy pain: a study with the intra-individual design. Int J Pediatr Otorhinolaryngol 68(11):1391-1395.
22. Hultcrantz E, Linder A, Markstrom A (2005) Long-term eVects of intracapsular partial tonsillectomy (tonsillotomy) compared with full tonsillectomy. Int J Pediatr Otorhinolaryngol 69(4):463-469.
23. Noordzij JP, Affleck BD (2006) Coblation versus unipolar electrocautery tonsillectomy: a prospective, randomized, single-blind study in adult patients. Laryngoscope 116(8):1303-1309.
24. Kujawski O, Dulguerov P, Gysin C, Lehmann W (1997) Microscopic tonsillectomy: a double-blind randomized trial. Otolaryngol Head Neck Surg 117(6):641-647.
25. Haddow K, Montague ML, Hussain SS (2006) Post-tonsillectomy haemorrhage: a prospective, randomized, controlled clinical trial of cold dissection versus bipolar diathermy dissection. J Laryngol Otol 120(6):450-454.
26. Klug TE, Ovesen T (2006) Post-tonsillectomy hemorrhage: incidence and risk factors. Ugeskr Laeger 168(26-32):2559-2562.
27. Malamed SF (2000) New anesthetics. Rev Belge Med Dent 55(1):9-18.
28. Woolf CJ, Shortland P, Coggeshall RE (1992) Peripheral nerve injury triggers central sprouting of myelinated afferents. Nature 355(6355):75-78.
29. Puente-Egido JJ, Dudeck J, Nolte H (1967) The clinical use of the local anesthetic marcain (Carbostesin). Anaesthesist 16(8):224-226.
30. Rasgon BM, Cruz RM, Hilsinger RL Jr et al (1991) Infiltration of epinephrine in tonsillectomy: a randomized, prospective, doubleblind study. Laryngoscope 101(2):114-118.
31. Binning R, Watson WR, Samrah M, Martin E (1962) Premedication for adenotonsillectomy. Br J Anaesth 34:812-816.
32. Windfuhr JP (2008) Steroids for reduction of morbidity following tonsillectomy. HNO 56(1):43-53.