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Volumn 66, Issue 1, 2010, Pages 15-21

Modulatory effect of N-acetylcysteine on pro-antioxidant status and haematological response in healthy men

Author keywords

Erythropoietin; Glutathione; Lipid peroxidation; Protein carbonylation; Thiols

Indexed keywords

ACETYLCYSTEINE; ERYTHROPOIETIN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HEMOGLOBIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

EID: 77955092559     PISSN: 11387548     EISSN: 18778755     Source Type: Journal    
DOI: 10.1007/s13105-010-0002-1     Document Type: Article
Times cited : (28)

References (29)
  • 1
    • 44349104572 scopus 로고    scopus 로고
    • The antioxidant role of glutathione and N-acetylcysteine supplements and exerciseinduced oxidative stress
    • Kerksick C, Willoughby D (2005) The antioxidant role of glutathione and N-acetylcysteine supplements and exerciseinduced oxidative stress. J Int Soc Sports Nutr 2:38-44.
    • (2005) J Int Soc Sports Nutr , vol.2 , pp. 38-44
    • Kerksick, C.1    Willoughby, D.2
  • 2
    • 0033837781 scopus 로고    scopus 로고
    • Thiol homeostasis and supplements in physical exercise
    • Sen CK, Packer L (2000) Thiol homeostasis and supplements in physical exercise. Am J Clin Nutr 72:653-669.
    • (2000) Am J Clin Nutr , vol.72 , pp. 653-669
    • Sen, C.K.1    Packer, L.2
  • 3
    • 0037377633 scopus 로고    scopus 로고
    • N-acetylcysteine infusion alters blood redox status but not time to fatigue during intense exercise in humans
    • Medved I, Brown MJ, Bjorksten AR, Leppik JA, Sostaric S, McKenna MJ (2003) N-acetylcysteine infusion alters blood redox status but not time to fatigue during intense exercise in humans. J Appl Physiol 94:1572-1582.
    • (2003) J Appl Physiol , vol.94 , pp. 1572-1582
    • Medved, I.1    Brown, M.J.2    Bjorksten, A.R.3    Leppik, J.A.4    Sostaric, S.5    McKenna, M.J.6
  • 4
    • 0028282599 scopus 로고
    • Oxidative stress after exercise: Effect of N-acetylcysteine supplementation
    • Sen CK, Rankinen T, Vaisanen S, Rauramaa R (1994) Oxidative stress after exercise: effect of N-acetylcysteine supplementation. J Appl Physiol 76:2570-2577.
    • (1994) J Appl Physiol , vol.76 , pp. 2570-2577
    • Sen, C.K.1    Rankinen, T.2    Vaisanen, S.3    Rauramaa, R.4
  • 5
    • 0035884859 scopus 로고    scopus 로고
    • Supplementation with vitamin C and Nacetylcysteine increases oxidative stress in humans after an acute muscle injury induced by eccentric exercise
    • Childs A, Jacobs C, Kaminski T, Halliwell B, Leeuwenburgh C (2001) Supplementation with vitamin C and Nacetylcysteine increases oxidative stress in humans after an acute muscle injury induced by eccentric exercise. Free Rad Biol Med 31:745-753.
    • (2001) Free Rad Biol Med , vol.31 , pp. 745-753
    • Childs, A.1    Jacobs, C.2    Kaminski, T.3    Halliwell, B.4    Leeuwenburgh, C.5
  • 6
    • 0026472927 scopus 로고
    • Failure of N-acetylcysteine to reduce low-density lipoprotein oxidizability in healthy subjects
    • Kleinveld HA, Demacker PN, Stalenhoef AF (1992) Failure of N-acetylcysteine to reduce low-density lipoprotein oxidizability in healthy subjects. Eur J Clin Pharmacol 43:639-642.
    • (1992) Eur J Clin Pharmacol , vol.43 , pp. 639-642
    • Kleinveld, H.A.1    Demacker, P.N.2    Stalenhoef, A.F.3
  • 7
    • 33847009422 scopus 로고    scopus 로고
    • Antioxidant N-acetylcysteine inhibits erythropoietininduced differentation of erythroid progenitors derived from mouse fetal liver
    • Nagata M, Arimitsu N, Ito T, Sekimizu K (2007) Antioxidant N-acetylcysteine inhibits erythropoietininduced differentation of erythroid progenitors derived from mouse fetal liver. Cell Biol Int 31:252-256.
    • (2007) Cell Biol Int , vol.31 , pp. 252-256
    • Nagata, M.1    Arimitsu, N.2    Ito, T.3    Sekimizu, K.4
  • 9
    • 0036205024 scopus 로고    scopus 로고
    • Influence of controlled hypoxia and radical scavenging agents on erythropoietin and malondialdehyde concentrations in humans
    • Freudenthaler SM, Schreeb KH, Wiese A, Pilz J, Gleiter CH (2002) Influence of controlled hypoxia and radical scavenging agents on erythropoietin and malondialdehyde concentrations in humans. Acta Physiol Scand 174:231-235.
    • (2002) Acta Physiol Scand , vol.174 , pp. 231-235
    • Freudenthaler, S.M.1    Schreeb, K.H.2    Wiese, A.3    Pilz, J.4    Gleiter, C.H.5
  • 10
    • 27144533632 scopus 로고    scopus 로고
    • Effects of N-acetylcysteine on glutathione oxidation and fatigue during handgrip exercise
    • Matuszczak Y, Farid M, Jones J, Lansdowne S, Smith MA, Taylor AA (2005) Effects of N-acetylcysteine on glutathione oxidation and fatigue during handgrip exercise.Muscle Nerve 32:633-638.
    • (2005) Muscle Nerve , vol.32 , pp. 633-638
    • Matuszczak, Y.1    Farid, M.2    Jones, J.3    Lansdowne, S.4    Smith, M.A.5    Taylor, A.A.6
  • 11
    • 0346102467 scopus 로고    scopus 로고
    • Effects of intravenous N-acetylcysteine infusion on time to fatigue and potassium regulation during prolonged cycling exercise
    • Medved I, Brown MJ, Bjorksten AR, McKenna MJ (2004) Effects of intravenous N-acetylcysteine infusion on time to fatigue and potassium regulation during prolonged cycling exercise. J Appl Physiol 96:211-217.
    • (2004) J Appl Physiol , vol.96 , pp. 211-217
    • Medved, I.1    Brown, M.J.2    Bjorksten, A.R.3    Mckenna, M.J.4
  • 13
    • 73649194769 scopus 로고
    • Improved method for determination of blood glutathione
    • Beutler E, Duron O, Mikus KB (1963) Improved method for determination of blood glutathione. J Lab ClinMed 61:882-888.
    • (1963) J Lab ClinMed , vol.61 , pp. 882-888
    • Beutler, E.1    Duron, O.2    Mikus, K.B.3
  • 14
    • 0025102226 scopus 로고
    • Determination of carbonyl content in oxidatively modified proteins
    • Levine RL, Garland D, Oliver CN (1990) Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol 186:464-479.
    • (1990) Methods Enzymol , vol.186 , pp. 464-479
    • Levine, R.L.1    Garland, D.2    Oliver, C.N.3
  • 15
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 16
    • 0042934808 scopus 로고
    • The thiobarbituric acid assay
    • Rice-Evans CA, Diplock AT, Symons MCR (eds), Elsevier, Amsterdam
    • Buege J, Aust SD (1991) The thiobarbituric acid assay. In: Rice-Evans CA, Diplock AT, Symons MCR (eds) Techniques in Free Radical Research. Elsevier, Amsterdam, pp 147-148.
    • (1991) Techniques in Free Radical Research , pp. 147-148
    • Buege, J.1    Aust, S.D.2
  • 17
    • 77957001732 scopus 로고
    • Reaction of protein sulfhydryl groups with Ellman's reagent
    • Hebeeb AFSA (1972) Reaction of protein sulfhydryl groups with Ellman's reagent. Methods Enzymol 25:457-464.
    • (1972) Methods Enzymol , vol.25 , pp. 457-464
    • Hebeeb, A.F.S.A.1
  • 18
    • 0001089359 scopus 로고
    • Water diuresis produced during recumbency by the intravenous infusion of isotonic saline solution
    • Strauss MB, Davis RK, Rosenbaum JD, Rossmeisl EC (1951) Water diuresis produced during recumbency by the intravenous infusion of isotonic saline solution. J Clin Invest 30:862-868.
    • (1951) J Clin Invest , vol.30 , pp. 862-868
    • Strauss, M.B.1    Davis, R.K.2    Rosenbaum, J.D.3    Rossmeisl, E.C.4
  • 19
    • 0022869171 scopus 로고
    • Alternations in plasmavolume- corrected blood components of marathon runners and concomitant relationship to performance
    • Kraemer RR, Brown BS (1986) Alternations in plasmavolume- corrected blood components of marathon runners and concomitant relationship to performance. Eur J Appl Physiol 55:579-584.
    • (1986) Eur J Appl Physiol , vol.55 , pp. 579-584
    • Kraemer, R.R.1    Brown, B.S.2
  • 20
    • 0026495980 scopus 로고
    • Glutathione reductases from a variety are inhibited by physiological levels of glutathione
    • Sexton DJ, Mutus B (1992) Glutathione reductases from a variety are inhibited by physiological levels of glutathione. Comp Biochem Physiol 103:897-901.
    • (1992) Comp Biochem Physiol , vol.103 , pp. 897-901
    • Sexton, D.J.1    Mutus, B.2
  • 22
    • 0032039959 scopus 로고    scopus 로고
    • Clinical applications of N-acetylcysteine
    • Kelly GS (1998) Clinical applications of N-acetylcysteine. Altern Med Rev 3:114-127.
    • (1998) Altern Med Rev , vol.3 , pp. 114-127
    • Kelly, G.S.1
  • 23
    • 0037127295 scopus 로고    scopus 로고
    • Thiol oxidase activity of copper, zinc superoxide dismutase
    • Winterbourn CC, Peskin AV, Parsons-Mair HN (2002) Thiol oxidase activity of copper, zinc superoxide dismutase. J Biol Chem 277:1906-1911.
    • (2002) J Biol Chem , vol.277 , pp. 1906-1911
    • Winterbourn, C.C.1    Peskin, A.V.2    Parsons-Mair, H.N.3
  • 24
    • 0027970536 scopus 로고
    • Role of hydrogen peroxide in hypoxia-induced erythropoietin production
    • Fandrey J, Frede S, Jelkmann W (1994) Role of hydrogen peroxide in hypoxia-induced erythropoietin production. Biochem J 303:507-510. (Pubitemid 24317332)
    • (1994) Biochemical Journal , vol.303 , Issue.2 , pp. 507-510
    • Fandrey, J.1    Frede, S.2    Jelkmann, W.3
  • 25
    • 0029753008 scopus 로고    scopus 로고
    • Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its α-subunit
    • Huang LE, Arany Z, Livingston DM, Bunn HF (1996) Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its α-subunit. J Biol Chem 271:32253-32259.
    • (1996) J Biol Chem , vol.271 , pp. 32253-32259
    • Huang, L.E.1    Arany, Z.2    Livingston, D.M.3    Bunn, H.F.4
  • 26
    • 0031035729 scopus 로고    scopus 로고
    • Effects of antioxidant vitamins on renal and hepatic erythropoietin production
    • Jelkmann W, Pagel H, Hellwig T, Fandrey J (1997) Effects of antioxidant vitamins on renal and hepatic erythropoietin production. Kidney Int 51:497-501.
    • (1997) Kidney Int , vol.51 , pp. 497-501
    • Jelkmann, W.1    Pagel, H.2    Hellwig, T.3    Fandrey, J.4
  • 27
    • 1342304166 scopus 로고    scopus 로고
    • Antioxidant intervention does not affect the response of plasma erythropoietin to short-term normobaric hypoxia in humans
    • Niess AM, Fehrenbach E, Lorenz I, Müller A, Northoff H, Dickhuth HH (2004) Antioxidant intervention does not affect the response of plasma erythropoietin to short-term normobaric hypoxia in humans. J Appl Physiol 96:1231-1235.
    • (2004) J Appl Physiol , vol.96 , pp. 1231-1235
    • Niess, A.M.1    Fehrenbach, E.2    Lorenz, I.3    Müller, A.4    Northoff, H.5    Dickhuth, H.H.6
  • 28
    • 15444370716 scopus 로고    scopus 로고
    • Effect of antioxidant vitamin treatment on the time course of hematological and hemorheological alterations after an exhausting exercise episode in human subjects
    • Senturk UK, Yalcin O, Gunduz F, Kuru O, Meiselman HJ, Baskurt OK (2005) Effect of antioxidant vitamin treatment on the time course of hematological and hemorheological alterations after an exhausting exercise episode in human subjects. J Appl Physiol 98:1272-1279.
    • (2005) J Appl Physiol , vol.98 , pp. 1272-1279
    • Senturk, U.K.1    Yalcin, O.2    Gunduz, F.3    Kuru, O.4    Meiselman, H.J.5    Baskurt, O.K.6
  • 29
    • 33744784825 scopus 로고    scopus 로고
    • Effect of tea polyphenols on cytokine gene expression in rats with alcoholic liver disease
    • Zhang ZG, Xu P, Liu Q, Yu CH, Zhang Y, Chen SH (2006) Effect of tea polyphenols on cytokine gene expression in rats with alcoholic liver disease. Hepatobiliary Pancreat Dis Int 6:268-272.
    • (2006) Hepatobiliary Pancreat Dis Int , vol.6 , pp. 268-272
    • Zhang, Z.G.1    Xu, P.2    Liu, Q.3    Yu, C.H.4    Zhang, Y.5    Chen, S.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.