메뉴 건너뛰기




Volumn 28, Issue 35, 2010, Pages 5676-5685

Evaluation of yellow fever virus 17D strain as a new vector for HIV-1 vaccine development

Author keywords

17D; HIV 1; P24; Vaccine; Yellow fever virus

Indexed keywords

ANTIGEN P24; GAMMA INTERFERON; HUMAN IMMUNODEFICIENCY VIRUS 1 ANTIGEN P24; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; INTERLEUKIN 2; NONSTRUCTURAL PROTEIN 1; UNCLASSIFIED DRUG; VIRUS VECTOR; GAG PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; LIVE VACCINE; P24 PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS TYPE 1; RECOMBINANT VACCINE;

EID: 77955090269     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2010.06.052     Document Type: Article
Times cited : (25)

References (48)
  • 1
    • 41849127131 scopus 로고    scopus 로고
    • The spread, treatment, and prevention of HIV-1: evolution of a global epidemic
    • Cohen M.S., Hellmann N., Levy J.A., DeCock K., Lange J. The spread, treatment, and prevention of HIV-1: evolution of a global epidemic. J Clin Invest 2008, 118(4):1244-1254.
    • (2008) J Clin Invest , vol.118 , Issue.4 , pp. 1244-1254
    • Cohen, M.S.1    Hellmann, N.2    Levy, J.A.3    DeCock, K.4    Lange, J.5
  • 2
    • 56649114351 scopus 로고    scopus 로고
    • HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis
    • McElrath M.J., De Rosa S.C., Moodel Z., Dubey S., Kierstead L., Janes H., et al. HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis. Lancet 2008, 372(9653):1894-1905.
    • (2008) Lancet , vol.372 , Issue.9653 , pp. 1894-1905
    • McElrath, M.J.1    De Rosa, S.C.2    Moodel, Z.3    Dubey, S.4    Kierstead, L.5    Janes, H.6
  • 3
    • 3142696041 scopus 로고    scopus 로고
    • Yellow fever vaccine
    • Saunders, Philadelphia, WB, S. Ploktin, W. Orenstein (Eds.)
    • Monath T.P. Yellow fever vaccine. Vaccines 2004, 1095-1176. Saunders, Philadelphia, WB. 4th ed. S. Ploktin, W. Orenstein (Eds.).
    • (2004) Vaccines , pp. 1095-1176
    • Monath, T.P.1
  • 4
    • 0036343564 scopus 로고    scopus 로고
    • Human cytotoxic T lymphocyte responses to live attenuated 17D yellow fever vaccine: identification of HLA-B35-restricted CTL epitopes on nonstructural proteins NS1, NS2b, NS3, and the structural protein E
    • Co M.D., Terajima M., Cruz J., Ennis F.A., Rothman A. Human cytotoxic T lymphocyte responses to live attenuated 17D yellow fever vaccine: identification of HLA-B35-restricted CTL epitopes on nonstructural proteins NS1, NS2b, NS3, and the structural protein E. Virology 2002, 293:151-163.
    • (2002) Virology , vol.293 , pp. 151-163
    • Co, M.D.1    Terajima, M.2    Cruz, J.3    Ennis, F.A.4    Rothman, A.5
  • 5
    • 32944455665 scopus 로고    scopus 로고
    • Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity
    • Querec T., Bennouna S., Alkan S., Laouar Y., Gorden K., Flavell R., et al. Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity. J Exp Med 2006, 203(2):413-424.
    • (2006) J Exp Med , vol.203 , Issue.2 , pp. 413-424
    • Querec, T.1    Bennouna, S.2    Alkan, S.3    Laouar, Y.4    Gorden, K.5    Flavell, R.6
  • 6
    • 7644241258 scopus 로고    scopus 로고
    • ChimeriVax-West Nile virus live-attenuated vaccine: preclinical evaluation of safety, immunogenicity, and efficacy
    • Arroyo J., Miller C., Catalan J., Myers G.A., Ratterree M.S., Trent D.W., et al. ChimeriVax-West Nile virus live-attenuated vaccine: preclinical evaluation of safety, immunogenicity, and efficacy. J Virol 2004, 78(22):12497-12507.
    • (2004) J Virol , vol.78 , Issue.22 , pp. 12497-12507
    • Arroyo, J.1    Miller, C.2    Catalan, J.3    Myers, G.A.4    Ratterree, M.S.5    Trent, D.W.6
  • 7
    • 17644366837 scopus 로고    scopus 로고
    • Replication of chimeric yellow fever virus-dengue serotypes 1-4 virus vaccine strains in dendritic and hepatic cells
    • Brandler S., Brown N., Ermak T.H., Mitchell F., Parsons M., Zhang M., et al. Replication of chimeric yellow fever virus-dengue serotypes 1-4 virus vaccine strains in dendritic and hepatic cells. Am J Trop Med Hyg 2005, 72:74-81.
    • (2005) Am J Trop Med Hyg , vol.72 , pp. 74-81
    • Brandler, S.1    Brown, N.2    Ermak, T.H.3    Mitchell, F.4    Parsons, M.5    Zhang, M.6
  • 8
    • 33646244630 scopus 로고    scopus 로고
    • Cutaneous delivery of a live, attenuated chimeric flavivirus vaccine against Japanese encephalitis (ChimeriVax-JE) in non-human primates
    • Dean C.H., Alarcon J.B., Waterston A.M., Draper K., Early R., Guirakhoo F., et al. Cutaneous delivery of a live, attenuated chimeric flavivirus vaccine against Japanese encephalitis (ChimeriVax-JE) in non-human primates. Hum Vaccine 2005, 1(3):106-111.
    • (2005) Hum Vaccine , vol.1 , Issue.3 , pp. 106-111
    • Dean, C.H.1    Alarcon, J.B.2    Waterston, A.M.3    Draper, K.4    Early, R.5    Guirakhoo, F.6
  • 9
    • 33745237160 scopus 로고    scopus 로고
    • Live attenuated chimeric yellow fever dengue type 2 (ChimeriVax-DEN2) vaccine: phase I clinical trial for safety and immunogenicity: effect of yellow fever pre-immunity in induction of cross neutralizing antibody responses to all 4 dengue serotypes
    • Guirakhoo F., Kitchener S., Morrison D., Forrat R., McCarthy K., Nichols R., et al. Live attenuated chimeric yellow fever dengue type 2 (ChimeriVax-DEN2) vaccine: phase I clinical trial for safety and immunogenicity: effect of yellow fever pre-immunity in induction of cross neutralizing antibody responses to all 4 dengue serotypes. Hum Vaccine 2006, 2(2):60-67.
    • (2006) Hum Vaccine , vol.2 , Issue.2 , pp. 60-67
    • Guirakhoo, F.1    Kitchener, S.2    Morrison, D.3    Forrat, R.4    McCarthy, K.5    Nichols, R.6
  • 10
    • 1442333330 scopus 로고    scopus 로고
    • Chimeric flaviviruses: novel vaccines against dengue fever, tick-borne encephalitis, and Japanese encephalitis
    • Lai C.J., Monath T.P. Chimeric flaviviruses: novel vaccines against dengue fever, tick-borne encephalitis, and Japanese encephalitis. Adv Virus Res 2003, 61:469-509.
    • (2003) Adv Virus Res , vol.61 , pp. 469-509
    • Lai, C.J.1    Monath, T.P.2
  • 12
    • 25144523093 scopus 로고    scopus 로고
    • New developments in flavivirus vaccines with special attention to yellow fever
    • Pugachev K.V., Guirakhoo F., Monath T.P. New developments in flavivirus vaccines with special attention to yellow fever. Curr Opin Infect Dis 2005, 18:387-394.
    • (2005) Curr Opin Infect Dis , vol.18 , pp. 387-394
    • Pugachev, K.V.1    Guirakhoo, F.2    Monath, T.P.3
  • 15
    • 0024892209 scopus 로고
    • Transcription of infectious yellow fever RNA from full-length cDNA templates produced by in vitro ligation
    • Rice C.M., Grakoui A., Galler R., Chambers T.J. Transcription of infectious yellow fever RNA from full-length cDNA templates produced by in vitro ligation. New Biol 1989, 1:285-296.
    • (1989) New Biol , vol.1 , pp. 285-296
    • Rice, C.M.1    Grakoui, A.2    Galler, R.3    Chambers, T.J.4
  • 16
    • 1242319434 scopus 로고    scopus 로고
    • Uncleaved NS2-3 is required for production of infectious bovine viral diarrhea virus
    • Agapov E.V., Murray C.L., Frolov I., Qu L., Myers T.M., Rice C.M. Uncleaved NS2-3 is required for production of infectious bovine viral diarrhea virus. J Virol 2004, 78(5):2414-2425.
    • (2004) J Virol , vol.78 , Issue.5 , pp. 2414-2425
    • Agapov, E.V.1    Murray, C.L.2    Frolov, I.3    Qu, L.4    Myers, T.M.5    Rice, C.M.6
  • 17
    • 32444435210 scopus 로고    scopus 로고
    • Time- and temperature-dependent activation of hepatitis C virus for low-pH-triggered entry
    • Tscherne D.M., Jones C.T., Evans M.J., Lindenbach B.D., McKeating J.A., Rice C.M. Time- and temperature-dependent activation of hepatitis C virus for low-pH-triggered entry. J Virol 2006, 80:1734-1741.
    • (2006) J Virol , vol.80 , pp. 1734-1741
    • Tscherne, D.M.1    Jones, C.T.2    Evans, M.J.3    Lindenbach, B.D.4    McKeating, J.A.5    Rice, C.M.6
  • 18
    • 0032845108 scopus 로고    scopus 로고
    • Mutagenesis of the NS2B-NS3-mediated cleavage site in the flavivirus capsid protein demonstrates a requirement for coordinated processing
    • Amberg S.M., Rice C.M. Mutagenesis of the NS2B-NS3-mediated cleavage site in the flavivirus capsid protein demonstrates a requirement for coordinated processing. J Virol 1999, 73:8083-8094.
    • (1999) J Virol , vol.73 , pp. 8083-8094
    • Amberg, S.M.1    Rice, C.M.2
  • 19
    • 47749087413 scopus 로고    scopus 로고
    • Comprehensive analysis of T cell epitope discovery strategies using 17DD yellow fever virus structural proteins and BALB/c (H2d) mice model
    • Maciel M., Kellathur S.N., Chikhlikar P., Dhalia R., Sidney J., Sette A., et al. Comprehensive analysis of T cell epitope discovery strategies using 17DD yellow fever virus structural proteins and BALB/c (H2d) mice model. Virology 2008, 378(1):105-117.
    • (2008) Virology , vol.378 , Issue.1 , pp. 105-117
    • Maciel, M.1    Kellathur, S.N.2    Chikhlikar, P.3    Dhalia, R.4    Sidney, J.5    Sette, A.6
  • 20
    • 40449101338 scopus 로고    scopus 로고
    • Evaluation of an indirect immunofluorescence assay for detection of immunoglobulin M (IgM) and IgG antibodies against yellow fever virus
    • Niedrig M., Kürsteiner O., Herzog C., Sonnenberg K. Evaluation of an indirect immunofluorescence assay for detection of immunoglobulin M (IgM) and IgG antibodies against yellow fever virus. Clin Vaccine Immunol 2008, 15(2):177-181.
    • (2008) Clin Vaccine Immunol , vol.15 , Issue.2 , pp. 177-181
    • Niedrig, M.1    Kürsteiner, O.2    Herzog, C.3    Sonnenberg, K.4
  • 21
    • 37849051431 scopus 로고    scopus 로고
    • Construction and characterization of recombinant flaviviruses bearing insertions between E and NS1 genes
    • Ronaldo M.C., Mello S.M., Trindade G.F., Rangel A.A., Duarte A.S., Oliveira P.J., et al. Construction and characterization of recombinant flaviviruses bearing insertions between E and NS1 genes. Virol J 2007, 30(4):115.
    • (2007) Virol J , vol.30 , Issue.4 , pp. 115
    • Ronaldo, M.C.1    Mello, S.M.2    Trindade, G.F.3    Rangel, A.A.4    Duarte, A.S.5    Oliveira, P.J.6
  • 22
    • 0037303672 scopus 로고    scopus 로고
    • Fine mapping of a cis-acting sequence element in yellow fever virus RNA that is required for RNA replication and cyclization
    • Corver J., Lenches E., Smith K., Robison R.A., Sando T., Strauss E.G., et al. Fine mapping of a cis-acting sequence element in yellow fever virus RNA that is required for RNA replication and cyclization. J Virol 2003, 77(3):2265-2270.
    • (2003) J Virol , vol.77 , Issue.3 , pp. 2265-2270
    • Corver, J.1    Lenches, E.2    Smith, K.3    Robison, R.A.4    Sando, T.5    Strauss, E.G.6
  • 23
    • 0023645817 scopus 로고
    • Conserved elements in the 3' untranslated region of flavivirus RNAs and potential cyclization sequences
    • Hahn C.S., Hahn Y.S., Rice C.M., Lee E., Dalgarno L., Strauss E.G., et al. Conserved elements in the 3' untranslated region of flavivirus RNAs and potential cyclization sequences. J Mol Biol 1987, 198:33-41.
    • (1987) J Mol Biol , vol.198 , pp. 33-41
    • Hahn, C.S.1    Hahn, Y.S.2    Rice, C.M.3    Lee, E.4    Dalgarno, L.5    Strauss, E.G.6
  • 24
    • 0034984219 scopus 로고    scopus 로고
    • Essential role of cyclization sequences in flavivirus RNA replication
    • Khromykh A.A., Meka H., Guyatt K.J., Westaway E.G. Essential role of cyclization sequences in flavivirus RNA replication. J Virol 2001, 75:6719-6728.
    • (2001) J Virol , vol.75 , pp. 6719-6728
    • Khromykh, A.A.1    Meka, H.2    Guyatt, K.J.3    Westaway, E.G.4
  • 25
    • 0027043276 scopus 로고
    • Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene
    • Daniel M.D., Kirchhoff F., Csajak S.C., Sehgal P.K., Desrosiers R.C. Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene. Science 1992, 258(5090):1938-1941.
    • (1992) Science , vol.258 , Issue.5090 , pp. 1938-1941
    • Daniel, M.D.1    Kirchhoff, F.2    Csajak, S.C.3    Sehgal, P.K.4    Desrosiers, R.C.5
  • 26
    • 0242289408 scopus 로고    scopus 로고
    • Neurovirulence of yellow fever 17DD vaccine virus to rhesus monkeys
    • Marchevsky R.S., Freire M.S., Coutinho E.S., Galler R. Neurovirulence of yellow fever 17DD vaccine virus to rhesus monkeys. Virology 2003, 316:55-63.
    • (2003) Virology , vol.316 , pp. 55-63
    • Marchevsky, R.S.1    Freire, M.S.2    Coutinho, E.S.3    Galler, R.4
  • 29
    • 13244267195 scopus 로고    scopus 로고
    • Yellow fever 17D as a vaccine vector for microbial CTL epitopes: protection in a rodent malaria model
    • Tao D., Barba-Spaeth G., Rai U., Nussenzweig V., Rice C.M., Nussenzweig R.S. Yellow fever 17D as a vaccine vector for microbial CTL epitopes: protection in a rodent malaria model. J Exp Med 2005, 201(2):201-209.
    • (2005) J Exp Med , vol.201 , Issue.2 , pp. 201-209
    • Tao, D.1    Barba-Spaeth, G.2    Rai, U.3    Nussenzweig, V.4    Rice, C.M.5    Nussenzweig, R.S.6
  • 30
    • 27744510434 scopus 로고    scopus 로고
    • Live attenuated yellow fever 17D infects human DCs and allows for presentation of endogenous and recombinant T cell epitopes
    • Barba-Spaeth G., Longman R.S., Albert M.L., Rice C.M. Live attenuated yellow fever 17D infects human DCs and allows for presentation of endogenous and recombinant T cell epitopes. J Exp Med 2005, 202(9):1179-1184.
    • (2005) J Exp Med , vol.202 , Issue.9 , pp. 1179-1184
    • Barba-Spaeth, G.1    Longman, R.S.2    Albert, M.L.3    Rice, C.M.4
  • 31
    • 0033803502 scopus 로고    scopus 로고
    • Recombinant yellow fever viruses are effective therapeutic vaccines for treatment of murine experimental solid tumors and pulmonary metastases
    • McAllister A., Arbetman A.E., Mandl S., Pena-Rossi C., Andino R. Recombinant yellow fever viruses are effective therapeutic vaccines for treatment of murine experimental solid tumors and pulmonary metastases. J Virol 2000, 74(19):9197-9205.
    • (2000) J Virol , vol.74 , Issue.19 , pp. 9197-9205
    • McAllister, A.1    Arbetman, A.E.2    Mandl, S.3    Pena-Rossi, C.4    Andino, R.5
  • 32
    • 3142726329 scopus 로고    scopus 로고
    • Current assessment of yellow fever and yellow fever vaccine
    • Lefeuvre A., Marianneau P., Deubel V. Current assessment of yellow fever and yellow fever vaccine. Curr Infect Dis Rep 2004, 6:96-104.
    • (2004) Curr Infect Dis Rep , vol.6 , pp. 96-104
    • Lefeuvre, A.1    Marianneau, P.2    Deubel, V.3
  • 33
    • 59649129816 scopus 로고    scopus 로고
    • Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses
    • Gaucher D., Therrien R., Kettaf N., Angermann B.R., Boucher G., Filali-Mouhim A., et al. Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses. J Exp Med 2008, 205(13):3119-3131.
    • (2008) J Exp Med , vol.205 , Issue.13 , pp. 3119-3131
    • Gaucher, D.1    Therrien, R.2    Kettaf, N.3    Angermann, B.R.4    Boucher, G.5    Filali-Mouhim, A.6
  • 34
    • 57849085182 scopus 로고    scopus 로고
    • Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans
    • Querec T.D., Akondy R.S., Lee E.K., Cao W., Nakaya H.I., Teuwen D., et al. Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans. Nat Immunol 2009, 10(1):116-125.
    • (2009) Nat Immunol , vol.10 , Issue.1 , pp. 116-125
    • Querec, T.D.1    Akondy, R.S.2    Lee, E.K.3    Cao, W.4    Nakaya, H.I.5    Teuwen, D.6
  • 35
    • 84993914879 scopus 로고    scopus 로고
    • HIV: bigger T-cell response not necessarily better
    • Minton K. HIV: bigger T-cell response not necessarily better. Nat Rev Immunol 2001, 7:88-89.
    • (2001) Nat Rev Immunol , vol.7 , pp. 88-89
    • Minton, K.1
  • 37
    • 4043176043 scopus 로고    scopus 로고
    • Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides
    • Kaufmann D.E., Bailey P.M., Sidney J., Wagner B., Norris P.J., Johnston M.N., et al. Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides. J Virol 2004, 78:4463-4477.
    • (2004) J Virol , vol.78 , pp. 4463-4477
    • Kaufmann, D.E.1    Bailey, P.M.2    Sidney, J.3    Wagner, B.4    Norris, P.J.5    Johnston, M.N.6
  • 38
    • 0037302428 scopus 로고    scopus 로고
    • Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load
    • Addo M.M., Yu X.G., Rathod A., Cohen D., Eldridge R.L., Strick D., et al. Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load. J Virol 2003, 77:2081-2092.
    • (2003) J Virol , vol.77 , pp. 2081-2092
    • Addo, M.M.1    Yu, X.G.2    Rathod, A.3    Cohen, D.4    Eldridge, R.L.5    Strick, D.6
  • 39
    • 0035198096 scopus 로고    scopus 로고
    • Analysis of total human immunodeficiency virus (HIV)-specific CD4(+) and CD8(+) T-cell responses: relationship to viral load in untreated HIV infection
    • Betts M.R., Ambrozak D.R., Douek D.C., Bonhoeffer S., Brenchley J.M., Casazza J.P., et al. Analysis of total human immunodeficiency virus (HIV)-specific CD4(+) and CD8(+) T-cell responses: relationship to viral load in untreated HIV infection. J Virol 2001, 75:11983-11991.
    • (2001) J Virol , vol.75 , pp. 11983-11991
    • Betts, M.R.1    Ambrozak, D.R.2    Douek, D.C.3    Bonhoeffer, S.4    Brenchley, J.M.5    Casazza, J.P.6
  • 41
    • 38949168855 scopus 로고    scopus 로고
    • Broad and Gag-biased HIV-1 epitope repertoires are associated with lower viral loads
    • Rolland M., Heckerman D., Deng W., Rousseau C.M., Coovadia H., Bishop K., et al. Broad and Gag-biased HIV-1 epitope repertoires are associated with lower viral loads. PLoS ONE 2008, 3(1):e1424.
    • (2008) PLoS ONE , vol.3 , Issue.1
    • Rolland, M.1    Heckerman, D.2    Deng, W.3    Rousseau, C.M.4    Coovadia, H.5    Bishop, K.6
  • 43
    • 70249116808 scopus 로고    scopus 로고
    • Development of more efficient and effective DNA vaccines
    • Apostolopoulos V., Weiner D.B. Development of more efficient and effective DNA vaccines. Expert Rev Vaccines 2009, 8(9):1133-1134.
    • (2009) Expert Rev Vaccines , vol.8 , Issue.9 , pp. 1133-1134
    • Apostolopoulos, V.1    Weiner, D.B.2
  • 44
    • 67649482320 scopus 로고    scopus 로고
    • Co-immunization with an optimized IL15 plasmid adjuvant enhances humoral immunity via stimulating B cells induced by genetically engineered DNA vaccines expressing consensus JEV and WNV E DIII
    • Ramanathan M.P., Kutzler M.A., Kuo Y.C., Yan J., Liu H., Shah V., et al. Co-immunization with an optimized IL15 plasmid adjuvant enhances humoral immunity via stimulating B cells induced by genetically engineered DNA vaccines expressing consensus JEV and WNV E DIII. Vaccine 2009, 27(32):4370-4380.
    • (2009) Vaccine , vol.27 , Issue.32 , pp. 4370-4380
    • Ramanathan, M.P.1    Kutzler, M.A.2    Kuo, Y.C.3    Yan, J.4    Liu, H.5    Shah, V.6
  • 45
    • 70349383965 scopus 로고    scopus 로고
    • High dose of plasmid IL-15 inhibits immune responses in an influenza non-human primates immunogenicity model
    • Yin J., Dai A., Laddy D.J., Yan J., Arango T., Khan A.S., et al. High dose of plasmid IL-15 inhibits immune responses in an influenza non-human primates immunogenicity model. Virology 2009, 393(1):49-55.
    • (2009) Virology , vol.393 , Issue.1 , pp. 49-55
    • Yin, J.1    Dai, A.2    Laddy, D.J.3    Yan, J.4    Arango, T.5    Khan, A.S.6
  • 47
    • 41149096579 scopus 로고    scopus 로고
    • T-cell quality in memory and protection: implications for vaccine design
    • Seder R.A., Darrah P.A., Roederer M. T-cell quality in memory and protection: implications for vaccine design. Nat Rev Immunol 2008, 8(4):247-258.
    • (2008) Nat Rev Immunol , vol.8 , Issue.4 , pp. 247-258
    • Seder, R.A.1    Darrah, P.A.2    Roederer, M.3
  • 48
    • 34250303350 scopus 로고    scopus 로고
    • Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major
    • Darrah P.A., Patel D.T., De Luca P.M., Lindsay R.W., Davey D.F., Flynn B.J., et al. Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major. Nat Med 2007, 13(7):843-850.
    • (2007) Nat Med , vol.13 , Issue.7 , pp. 843-850
    • Darrah, P.A.1    Patel, D.T.2    De Luca, P.M.3    Lindsay, R.W.4    Davey, D.F.5    Flynn, B.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.