Anxiety, neuroticism and oxidative stress: Cross-sectional study in non-smoking college students

Psychiatry and Clinical Neurosciences

Volumn 64, Issue 4, 2010, Pages 435-441

  Matsushita, Masateru ^a,b,c   Kumano Go, Takayuki ^a,b,c   Suganuma, Nakamori ^a,b,c   Adachi, Hiroyoshi ^a,b,c   Yamamura, Schuhei ^a,c   Morishima, Hiroko ^a,c   Shigedo, Yoshihisa ^a,c   Mikami, Akira ^a,b,c   Takeda, Masatoshi ^a,c   Sugita, Yoshiro ^a,b,c  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY HOSPITAL   (Japan)

Author keywords

adolescent; anxiety; neuroticism; oxidative stress; personality

Indexed keywords

REACTIVE OXYGEN METABOLITE;

ADULT; ANXIETY; ARTICLE; CIGARETTE SMOKING; COLLEGE STUDENT; CONCENTRATION (PARAMETERS); CROSS-SECTIONAL STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NEO FIVE FACTOR INVENTORY; NEUROSIS; OXIDATIVE STRESS; PERSONALITY; PSYCHOLOGIC TEST; SEX DIFFERENCE; STATE TRAIT ANXIETY INVENTORY; BLOOD; CHI SQUARE DISTRIBUTION; METABOLISM; NONPARAMETRIC TEST; PATHOPHYSIOLOGY; PERSONALITY TEST; PHYSIOLOGY; PSYCHOLOGY; STUDENT; YOUNG ADULT;

ANXIETY; CHI-SQUARE DISTRIBUTION; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; MALE; NEUROTIC DISORDERS; OXIDATIVE STRESS; PERSONALITY; PERSONALITY INVENTORY; REACTIVE OXYGEN SPECIES; SEX FACTORS; STATISTICS, NONPARAMETRIC; STUDENTS; YOUNG ADULT;

EID: 77955080062     PISSN: 13231316     EISSN: 14401819     Source Type: Journal    
DOI: 10.1111/j.1440-1819.2010.02109.x     Document Type: Article

References (30)

1. Schatzberg AF, Samson JA, Rothschild AJ, Bond TC, Regier DA. McLean Hospital depression research facility: early-onset phobic disorders and adult-onset major depression. Br. J. Psychiatry Suppl. 1998 34 : 29 34.
2. Smoller JW. Genetic boundary violations: phobic disorders and personality. Am. J. Psychiatry 2007 164 : 1631 1633.
3. Irie M, Asami S, Ikeda M, Kasai H. Depressive state relates to female oxidative DNA damage via neutrophil activation. Biochem. Biophys. Res. Commun. 2003 311 : 1014 1018.
4. Khanzode SD, Dakhale GN, Khanzode SS, Saoji A, Palasodkar R. Oxidative damage and major depression: the potential antioxidant action of selective serotonin re-uptake inhibitors. Redox Rep. 2003 8 : 365 370.
5. Cumurcu BE, Ozyurt H, Etikan I, Demir S, Karlidag R. Total antioxidant capacity and total oxidant status in patients with major depression: impact of antidepressant treatment. Psychiatry Clin. Neurosci. 2009 63 : 639 645.
6. Sarandol A, Sarandol E, Eker SS, Erdinc S, Vatansever E, Kirli S. Major depressive disorder is accompanied with oxidative stress: short-term antidepressant treatment does not alter oxidative-antioxidative systems. Hum. Psychopharmacol. 2007 22 : 67 73.
7. Ng F, Berk M, Dean O, Bush AI. Oxidative stress in psychiatric disorders: evidence base and therapeutic implications. Int. J. Neuropsychophamacol. 2008 21 : 1 26.
8. Pazvantoglu O, Selek S, Okay IT et al. Oxidative mechanisms in schizophrenia and their relationship with illness subtype and symptom profile. Psychiatry Clin. Neurosci. 2009 63 : 693 700.
9. Bilici M, Efe H, Köroǧlu MA, Uydu HA, Bekaroǧlu M, Deǧer O. Antioxidative enzyme activities and lipid peroxidation in major depression: alterations by antidepressant treatments. J. Affect. Disord. 2001 64 : 43 51.
10. Atmaca M, Kuloglu M, Tezcan E, Ustundag B. Antioxidant enzyme and malondialdehyde levels in patients with social phobia. Psychiatry Res. 2008 159 : 95 100.
11. de Oliveira MR, Silvestrin RB, Mello E Souza T, Moreira JC. Oxidative stress in the hippocampus, anxiety-like behavior and decreased locomotory and exploratory activity of adult rats: effects of sub acute vitamin A supplementation at therapeutic doses. Neurotoxicology 2007 28 : 1191 1199.
12. Bienvenu OJ, Hettema JM, Neale MC, Prescott CA, Kendler KS. Low extraversion and high neuroticism as indices of genetic and environmental risk for social phobia, agoraphobia, and animal phobia. Am. J. Psychiatry 2007 164 : 1714 1721.
13. Hettema JM, Neale MC, Myers JM, Prescott CA, Kendler KS. A population-based twin study of the relationship between neuroticism and internalizing disorders. Am. J. Psychiatry 2006 163 : 857 864.
14. Kendler KS, Gardner CO, Prescott CA. Personality and the experience of environmental adversity. Psychol. Med. 2003 33 : 1193 1202.
15. Fanous A, Gardner CO, Prescott CA, Cancro R, Kendler KS. Neuroticism, major depression and gender: a population-based twin study. Psychol. Med. 2002 32 : 719 728.
16. Bienvenu OJ, Brown C, Samuels JF et al. Normal personality traits and comorbidity among phobia, panic and major depressive disorders. Psychiatry Res. 2001 102 : 73 85.
17. Spielberger CD, Gorsuch RL, Lushene R et al. Manual for the State-Trait Anxiety Inventory (Form Y). Consulting Psychologists Press
18. Knight RG, Waal-Manning HJ, Spears GF. Some norms and reliability data for the State-Trait Anxiety Inventory and the Zung Self-Rating Depression Scale. Br. J. Clin. Psychol. 1983 22 : 245 249.
19. Costa PT, Jr., McCrae RR. Revised NEO Personality Inventory (NEO-PI-R) and NEO Five-Factor Inventory (NEO-FFI) Professional Manual. Psychological Assessment Resources
20. Atmaca M, Tezcan E, Kuloglu M, Ustundag B, Tunckol H. Antioxidant enzyme and malondialdehyde values in social phobia before and after citalopram treatment. Eur. Arch. Psychiatry Clin. Neurosci. 2004 254 : 231 235.
21. Kuloglu M, Atmaca M, Tezcan E, Gecici O, Tunckol H, Ustundag B. Antioxidant enzyme activities and malondialdehyde levels in patients with obsessive-compulsive disorder. Neuropsychobiology 2002 46 : 27 32. (Pubitemid 35002315)
22. Kuloglu M, Atmaca M, Tezcan E, Ustundag B, Bulut S. Antioxidant enzyme and malondialdehyde levels in patients with panic disorder. Neuropsychobiology 2002 46 : 186 189.
23. Maes M, Song C, Lin A et al. The effects of psychological stress on humans: increased production of pro-inflammatory cytokines and a Th1-like response in stress-induced anxiety. Cytokine 1998 10 : 313 318.
24. Arranz L, Guayerbas N, De la Fuente M. Impairment of several immune functions in anxious women. J. Psychosom. Res. 2007 62 : 1 8.
25. McCall MR, Frei B. Can antioxidant vitamins materially reduce oxidative damage in humans? Free Radic. Biol. Med. 1999 26 : 1034 1053.
26. Kikugawa K, Yasuhara Y, Ando K, Koyama K, Hiramoto K, Suzuki M. Effect of supplementation of n-3 polyunsaturated fatty acids on oxidative stress-induced DNA damage of rat hepatocytes. Biol. Pharm. Bull. 2003 26 : 1239 1244.
27. Kikugawa K, Yasuhara Y, Ando K, Koyama K, Hiramoto K, Suzuki M. Protective effect of supplementation of fish oil with high n-3 polyunsaturated fatty acids against oxidative stress-induced DNA damage of rat liver in vivo. J. Agric. Food Chem. 2003 51 : 6073 6079.
28. Lee TH, Hoover RL, Williams JD et al. Effect of dietary enrichment with eicosapentaenoic and docosahexaenoic acids on in vitro neutrophil and monocyte leukotriene generation and neutrophil function. N. Engl. J. Med. 1985 312 : 1217 1224.
29. Clark LA, Watson D, Mineka S. Temperament, personality, and the mood and anxiety disorders. J. Abnorm. Psychol. 2004 103 : 103 116.
30. Ormel J, Oldehinkel AJ, Brilman EI. The interplay and etiological continuity of neuroticism, difficulties, and life events in the etiology of major and subsyndromal, first and recurrent depressive episodes in later life. Am. J. Psychiatry. 2001 158 : 885 891.