The renaissance in HIV vaccine development - Future directions

New England Journal of Medicine

Volumn 363, Issue 5, 2010, Pages

  Koff, Wayne C ^a   Berkley, Seth F ^a  

^a INTERNATIONAL AIDS VACCINE INITIATIVE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; MONOCLONAL ANTIBODY; PRIMER DNA; PROTEIN SUBUNIT; SIMIAN IMMUNODEFICIENCY VIRUS VACCINE;

DRUG EFFICACY; DRUG SAFETY; HEALTH PROGRAM; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNIZATION; IMMUNOGENICITY; PRIORITY JOURNAL; PROPHYLAXIS; SHORT SURVEY; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS INFECTION; VIRUS ISOLATION; WORLD HEALTH ORGANIZATION;

EID: 77955067596     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMp1007629     Document Type: Article

References (5)

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2. Walker LM, Phogat SK, Chan-Hui PY, et al. Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. Science 2009;326:285-9.
3. Zhou, T. Georgiev, I, Wu X et al. Structural basis for the broad and potent neutralization of HIV-1 by antibody VRC01. Science 2010 July 8 (Epub ahead of print).
4. Hessell AJ, Rakasz EG, Tehrani DM, et al. Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L. J Virol 2010;84:1302-13.
5. Bianchi E, Joyce JG, Miller MD, et al. Vaccination with peptide mimetics of the gp41 prehairpin fusion intermediate yields neutralizing antisera against HIV-1 isolates. Proc Natl Acad Sci U S A 2010;107:10655-60.