Outcomes of nasopharyngeal carcinoma screening for high risk family members in Hong Kong

Familial Cancer

Volumn 9, Issue 2, 2010, Pages 221-228

  Ng, Wai Tong ^a   Wai Choi, Cheuk ^a   Lee, Michael C H ^a   Yau Law, Lai ^a   Kok Yau, Tsz ^a   Lee, Anne W M ^a  

^a PAMELA YOUDE NETHERSOLE EASTERN HOSPITAL   (Hong Kong)

Author keywords

Familial; Nasopharyngeal carcinoma; Screening

Indexed keywords

ADULT; ARTICLE; CANCER DIAGNOSIS; CANCER RISK; CANCER SCREENING; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE FREE SURVIVAL; EARLY DIAGNOSIS; EPSTEIN BARR VIRUS; FAMILY; FEMALE; HIGH RISK POPULATION; HONG KONG; HUMAN; MAJOR CLINICAL STUDY; MALE; NASOPHARYNX CARCINOMA; NONHUMAN; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PATIENT REFERRAL; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SAMPLE SIZE; SENSITIVITY AND SPECIFICITY; SEROLOGY; STATISTICAL SIGNIFICANCE; SURVIVAL RATE; TREATMENT OUTCOME;

HUMAN HERPESVIRUS 4;

EID: 77955057739     PISSN: 13899600     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10689-009-9296-y     Document Type: Article

References (29)

1. Lee AW, Foo W, Law SC et al (1997) Nasopharyngeal carcinoma: presenting symptoms and duration before diagnosis. Hong Kong Med J 3(4):355-361
2. Chang ET, Adami HO (2006) The enigmatic epidemiology of nasopharyngeal carcinoma. Cancer Epidemiol Biomarkers Prev 15(10):1765-1777
3. Lee AW, Poon YF, Foo W et al (1992) Retrospective analysis of 5037 patients with nasopharyngeal carcinoma treated during 1976-1985: overall survival and patterns of failure. Int J Radiat Oncol Biol Phys 23(2):261-270
4. Lee AW, Sze WM, Au JS et al (2005) Treatment results for nasopharyngeal carcinoma in the modern era: the Hong Kong experience. Int J Radiat Oncol Biol Phys 61(4):1107-1116
5. Lee AW, Law SC, Ng SH et al (1992) Retrospective analysis of nasopharyngeal carcinoma treated during 1976-1985: late complications following megavoltage irradiation. Br J Radiol 65 (778):918-928
6. Old LJ, Boyse EA, Oettgen HF et al (1966) Precipitating antibody in human serum to an antigen present in cultured Burkitt's lymphoma cells. Proc Natl Acad Sci U S A 56(6):1699-1704
7. Pathmanathan R, Prasad U, Sadler R, Flynn K, Raab-Traub N (1995) Clonal proliferations of cells infected with Epstein-Barr virus in preinvasive lesions related to nasopharyngeal carcinoma. N Engl J Med 333(11):693-698
8. Raab-Traub N (2002) Epstein-Barr virus in the pathogenesis of NPC. Semin Cancer Biol 12(6):431-441
9. Ho HC, Ng MH, Kwan HC, Chau JC (1976) Epstein-Barr-virusspecific IgA and IgG serum antibodies in nasopharyngeal carcinoma. Br J Cancer 34(6):655-660
10. Ho HC, Kwan HC, Wu P, Chan SK, Ng MH, Saw D (1978) Epstein-Barr antibodies in suspected nasopharyngeal carcinoma. Lancet 2(8099):1094-1095
11. Williams EH, de The G (1974) Letter: familial aggregation in nasopharyngeal carcinoma. Lancet 2(7875):295-296
12. Jia WH, Feng BJ, Xu ZL et al (2004) Familial risk and clustering of nasopharyngeal carcinoma in Guangdong, China. Cancer 101(2): 363-369
13. Loh KS, Goh BC, Lu J, Hsieh WS, Tan L (2006) Familial nasopharyngeal carcinoma in a cohort of 200 patients. Arch Otolaryngol Head Neck Surg 132(1):82-85
14. Friborg J, Wohlfahrt J, Koch A, Storm H, Olsen OR, Melbye M (2005) Cancer susceptibility in nasopharyngeal carcinoma families-a population-based cohort study. Cancer Res 65(18):8567-8572
15. Ung A, Chen CJ, Levine PH et al (1999) Familial and sporadic cases of nasopharyngeal carcinoma in Taiwan. Anticancer Res 19(1B):661-665
16. Ng WT, Choi CW, Lee MC, Chan SH, Yau TK, Lee AW (2008) Familial nasopharyngeal carcinoma in Hong Kong: epidemiology and implication in screening. Fam Cancer 8:103-108
17. Ng WT, Yau TK, Yung RW et al (2005) Screening for family members of patients with nasopharyngeal carcinoma. Int J Cancer 113(6):998-1001
18. Duffy SW, Smith RA, Gabe R, Tabar L, Yen AM, Chen TH (2005) Screening for breast cancer. Surg Oncol Clin N Am 14(4): 671-697
19. Hong Kong Cancer Stat (2004) Hong Kong Cancer Registry, Hospital Authority 2007 [cited; Available from: www3.ha.org.hk/cancereg/eng/stat.asp
20. Zeng Y, Zhong JM, Li LY et al (1983) Follow-up studies on Epstein-Barr virus IgA/VCA antibody-positive persons in Zangwu County, China. Intervirology 20(4):190-194
21. Zeng Y, Zhang LG, Li HY et al (1982) Serological mass survey for early detection of nasopharyngeal carcinoma in Wuzhou City, China. Int J Cancer 29(2):139-141
22. Chen JY, Chen CJ, Liu MY et al (1989) Antibody to Epstein-Barr virus-specific DNase as a marker for field survey of patients with nasopharyngeal carcinoma in Taiwan. J Med Virol 27(4): 269-273
23. Zong YS, Sham JS, Ng MH et al (1992) Immunoglobulin a against viral capsid antigen of Epstein-Barr virus and indirect mirror examination of the nasopharynx in the detection of asymptomatic nasopharyngeal carcinoma. Cancer 69(1):3-7
24. Ji MF, Wang DK, Yu YL et al (2007) Sustained elevation of Epstein-Barr virus antibody levels preceding clinical onset of nasopharyngeal carcinoma. Br J Cancer 96(4):623-630
25. Zeng Y, Zhang LG, Wu YC et al (1985) Prospective studies on nasopharyngeal carcinoma in Epstein-Barr virus IgA/VCA antibody-positive persons in Wuzhou City, China. Int J Cancer 36 (5):545-547
26. Lo YM, Chan LY, Lo KW et al (1999) Quantitative analysis of cellfree Epstein-Barr virus DNA in plasma of patients with nasopharyngeal carcinoma. Cancer Res 59(6):1188-1191
27. Cho WC (2007) Nasopharyngeal carcinoma: molecular biomarker discovery and progress. Mol Cancer 6:1
28. Lo YM, Chan AT, Chan LY et al (2000) Molecular prognostication of nasopharyngeal carcinoma by quantitative analysis of circulating Epstein-Barr virus DNA. Cancer Res 60(24):6878-6881
29. Leung SF, Tam JS, Chan AT et al (2004) Improved accuracy of detection of nasopharyngeal carcinoma by combined application of circulating Epstein-Barr virus DNA and anti-Epstein-Barr viral capsid antigen IgA antibody. Clin Chem 50(2):339-345