Hepatic drug metabolizing profile of Flinders Sensitive Line rat model of depression

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 34, Issue 6, 2010, Pages 1075-1084

  Kotsovolou, Olga ^a   Ingelman Sundberg, Magnus ^b   Lang, Matti A ^c   Marselos, Marios ^a   Overstreet, David H ^d   Papadopoulou Daifoti, Zoi ^e   Johanson, Inger ^b   Fotopoulos, Andrew ^a   Konstandi, Maria ^a  

^a UNIVERSITY OF IOANNINA   (Greece)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UPPSALA UNIVERSITY   (Sweden)

^d UNIVERSITY OF NORTH CAROLINA   (United States)

^e UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Cytochromes; Depression; Drug metabolism; FSL; Mirtazapine; Rat

Indexed keywords

16ALPHA TESTOSTERONE HYDROXYLASE; 4 NITROPHENOL HYDROXYLASE; 7 ETHOXYRESORUFIN O DEALKYLASE; ALDEHYDE DEHYDROGENASE; BENZO[A]PYRENE; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2B1; CYTOCHROME P450 2B2; CYTOCHROME P450 2C11; CYTOCHROME P450 2D1; CYTOCHROME P450 2E1; CYTOCHROME P450 3A1; CYTOCHROME P450 3A2; GLUTATHIONE; GLUTATHIONE TRANSFERASE; LIVER ENZYME; MIRTAZAPINE; OXYGENASE; UNCLASSIFIED DRUG; CYTOCHROME P450; DOPAMINE; MIANSERIN; NORADRENALIN; TRICYCLIC ANTIDEPRESSANT AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEPRESSION; DRUG METABOLISM; DRUG TRANSFORMATION; ENZYME ACTIVITY; ENZYME INDUCTION; FLINDERS SENSITIVE LINE RAT; LIVER METABOLISM; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; RAT STRAIN; SPRAGUE DAWLEY RAT; STRAIN DIFFERENCE; ANALOGS AND DERIVATIVES; ANALYSIS OF VARIANCE; ANIMAL; COMPARATIVE STUDY; DISEASE MODEL; DRUG EFFECTS; ENZYMOLOGY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPOTHALAMUS; LIVER; METABOLISM; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BLOTTING, WESTERN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 ENZYME SYSTEM; DEPRESSIVE DISORDER; DISEASE MODELS, ANIMAL; DOPAMINE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HYPOTHALAMUS; LIVER; MALE; MIANSERIN; NOREPINEPHRINE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 77955054673     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2010.05.029     Document Type: Article

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