Selection of patients with germline MLH1 mutated Lynch syndrome by determination of MLH1 methylation and BRAF mutation

Familial Cancer

Volumn 9, Issue 2, 2010, Pages 167-172

  Bouzourene, Hanifa ^a   Hutter, Pierre ^b   Losi, Lorena ^c   Martin, Patricia ^a   Benhattar, Jean ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b Institut Central des Hopitaux Valaisans   (Switzerland)

^c UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

BRAF gene; BRAF mutation; Germline mutations; Hereditary colorectal cancer; Lynch syndrome; MLH1 gene; MLH1 methylation

Indexed keywords

B RAF KINASE; PROTEIN MLH1;

ALGORITHM; ARTICLE; CLINICAL ARTICLE; COLORECTAL CANCER; EXON; GENE AMPLIFICATION; GENE MUTATION; GENE SILENCING; GENETIC COUNSELING; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; METHYLATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEFECT; SINGLE STRAND CONFORMATION POLYMORPHISM;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AGED; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA METHYLATION; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; GERM-LINE MUTATION; HUMANS; MALE; MUTATION; MUTS HOMOLOG 2 PROTEIN; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS B-RAF;

EID: 77955053997     PISSN: 13899600     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10689-009-9302-4     Document Type: Article

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