Local gene expression and immune responses of vaginal DNA vaccination using a needle-free injector

International Journal of Pharmaceutics

Volumn 396, Issue 1-2, 2010, Pages 11-16

  Kanazawa, Takanori ^a   Takashima, Yuuki ^a   Tamura, Toshiaki ^a   Tsuchiya, Miki ^a   Shibata, Yasunori ^a   Udagawa, Haruhide ^b   Okada, Hiroaki ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b SHIMADZU CORPORATION   (Japan)

Author keywords

Cellular immunity; Local humoral immunity; Needle free injector; Vaginal DNA vaccine

Indexed keywords

DNA VACCINE; GAMMA INTERFERON; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; DNA IMMUNIZATION; EXPERIMENTAL RABBIT; FEMALE; GENE EXPRESSION; GENETIC TRANSFECTION; IMMUNE RESPONSE; INTERMETHOD COMPARISON; JET INJECTION; LYMPHOCYTE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; BLOOD; C57BL MOUSE; CELL CULTURE; CELLULAR IMMUNITY; GENE EXPRESSION REGULATION; GENE TRANSFER; GENETICS; HUMORAL IMMUNITY; IMMUNOLOGY; INTRAVAGINAL DRUG ADMINISTRATION; MUCOSA; MUCOSAL IMMUNITY; RABBIT; SEXUALLY TRANSMITTED DISEASES, VIRAL; SKIN; VAGINA; WISTAR RAT;

ADMINISTRATION, INTRAVAGINAL; ANIMALS; CELLS, CULTURED; FEMALE; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; IMMUNITY, CELLULAR; IMMUNITY, HUMORAL; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN G; INJECTIONS, JET; INTERFERON-GAMMA; MALE; MICE; MICE, INBRED C57BL; MUCOUS MEMBRANE; RABBITS; RATS; RATS, WISTAR; SEXUALLY TRANSMITTED DISEASES, VIRAL; SKIN; VACCINES, DNA; VAGINA;

EID: 77955049175     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.05.040     Document Type: Article

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