Kinetic characterization of salmonella FliK-FlhB interactions demonstrates complexity of the type III secretion substrate-specificity switch

Biochemistry

Volumn 49, Issue 30, 2010, Pages 6386-6393

  Morris, Daniel P ^a   Roush, Eric D ^b   Thompson, J Will ^a   Moseley, M Arthur ^a   Murphy, James W ^c   McMurry, Jonathan L ^d  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GE HEALTHCARE   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d KENNESAW STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOCATALYTIC; BACTERIAL FLAGELLUM; CONFORMATIONAL CHANGE; HOOK PROTEIN; INTERMEDIATE PRODUCT; KINETIC CHARACTERIZATION; KINETIC PROFILES; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; OPTICAL BIO-SENSING; STRUCTURAL DEFECT; SUBSTRATE SPECIFICITY; TYPE III SECRETIONS; WILD TYPES;

EXPERIMENTS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MUTAGENESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

PROTEINS;

BACTERIAL PROTEIN; FLHB PROTEIN; FLIK PROTEIN; MUTANT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL FLAGELLUM; BINDING AFFINITY; CATALYSIS; CHEMICAL REACTION KINETICS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN PROTEIN INTERACTION; PROTEIN VARIANT; SALMONELLA; WILD TYPE;

BACTERIAL PROTEINS; FLAGELLA; HYDROLYSIS; KINETICS; MEMBRANE PROTEINS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN TRANSPORT; SALMONELLA; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); SALMONELLA;

EID: 77955032705     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi100487p     Document Type: Article

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