Increased siglec-1 expression in monocytes of patients with primary biliary cirrhosis

Immunological Investigations

Volumn 39, Issue 6, 2010, Pages 645-660

  Bao, Guangyu ^c   Han, Zhijun ^b   Yan, Zihe ^b   Wang, Qihong ^a   Zhou, Ye ^a   Yao, Dingkang ^a   Gu, Mingli ^a   Chen, Bo ^a   Chen, Sunxiao ^a   Deng, Anmei ^a   Zhong, Renqian ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b WUXI NO 2 PEOPLE S HOSPITAL   (China)

^c Medical College of Southeast University   (China)

Author keywords

Biomarkers; Expression; Inflammatory responses; Primary biliary cirrhosis; Siglec 1

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ANTINUCLEAR ANTIBODY; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; BIOCHEMICAL MARKER; CD14 ANTIGEN; CHOLESTEROL; GAMMA GLUTAMYLTRANSFERASE; MEMBRANE ANTIGEN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; SIGLEC 1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CELL SEPARATION; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; GENETIC TRANSFECTION; HEPATITIS B; HUMAN; LIVER CIRRHOSIS; MALE; MONOCYTE; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; RNA INTERFERENCE;

AGED; ANTIGENS, CD14; CELLS, CULTURED; CYTOKINES; DISEASE PROGRESSION; FEMALE; HEPATITIS B; HUMANS; LIVER CIRRHOSIS, BILIARY; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; MONOCYTES; RECEPTORS, IMMUNOLOGIC; RNA, SMALL INTERFERING; UP-REGULATION;

EID: 77955001638     PISSN: 08820139     EISSN: 15324311     Source Type: Journal    
DOI: 10.3109/08820139.2010.485625     Document Type: Article

References (23)

1. Biesen, R., Demir, C., Barkhudarova, F., Grun, J. R., Steinbrich-Zollner, M., Backhaus, M., Haupl, T., Rudwaleit, M., Riemekasten, G., Radbruch, A., Hiepe, F., Burmester, G. R., Grutzkau, A. (2008). Sialic acid-binding ig-like lectin 1 expression in inflammatory and resident monocytes is a potential biomarker for monitoring disease activity and success of therapy in systemic lupus erythematosus. Arthritis Rheum. 58:1136-1145.
2. Charatcharoenwitthaya, P., Lindor, K. D. (2005). Current concepts in the pathogenesis of primary biliary cirrhosis. Ann. Hepatol. 4:161-175.
3. Crocker, P. R. (2002). Siglecs: Sialic-acid-binding immunoglobulin-like lectins in cellcell interactions and signalling. Curr. Opin. Struct. Biol, 12:609-615.
4. Crocker, P. R., Gordon, S. (1986). Properties and distribution of a lectin-like hemagglutinin differentially expressed by murine stromal tissue macrophages. J. Exp. Med. 164:1862-1875.
5. Crocker, P. R., Mucklow, S., Bouckson, V., McWilliam, A., Willis, A. C., Gordon, S., Milon, G., Kelm, S., Bradfield, P. (1994). Sialoadhesin, a macrophage sialic acid binding receptor for haemopoietic cells with 17 immunoglobulin-like domains. EMBO J. 13:4490-4503.
6. Crocker, P. R., Paulson, J. C., Varki, A. (2007). Siglecs and their roles in the immune system. Nat. Rev. Immunol. 7:255-266.
7. Crocker, P. R., Redelinghuys, P. (2008). Siglecs as positive and negative regulators of the immune system. Biochem. Soc. Trans. 36:1467-1471.
8. Heathcote, E. J. (2000). Management of primary biliary cirrhosis. The american association for the study of liver diseases practice guidelines. Hepatology 31: 1005-1013.
9. Ichiki, Y., Shimoda, S., Ishibashi, H., Gershwin, M. E. (2004). Is primary biliary cirrhosis a model autoimmune disease? Autoimmun. Rev. 3:331-336. (Pubitemid 38887629)
10. Ikezumi, Y., Suzuki, T., Hayafuji, S., Okubo, S., Nikolic-Paterson, D. J., Kawachi, H., Shimizu, F., Uchiyama, M. (2005). The sialoadhesin (cd169) expressing a macrophage subset in human proliferative glomerulonephritis. Nephrol. Dial. Transplant. 20:2704-2713.
11. Itakura, J., Izumi, N., Nishimura, Y., Inoue, K., Ueda, K., Nakanishi, H., Tsuchiya, K., Hamano, K., Asahina, Y., Kurosaki, M., Uchihara, M., Miyake, S. (2004). Prospective randomized crossover trial of combination therapy with bezafibrate and udca for primary biliary cirrhosis. Hepatol. Res. 29:216-222.
12. Kaplan, M. M., Gershwin, M. E. (2005), Primary biliary cirrhosis. N, Engl, J, Med, 353:1261-1273.
13. Lleo, A., Invernizzi, P., Mackay, I. R., Prince, H., Zhong, R. Q., Gershwin, M. E. (2008). Etiopathogenesis of primary biliary cirrhosis. World J. Gastroenterol.14: 3328-3337.
14. Oetke, C., Vinson, M. C., Jones, C., Crocker, P. R. (2006). Sialoadhesin-deficient mice exhibit subtle changes in b- and t-cell populations and reduced immunoglobulin mlevels. Mol. Cell Biol. 26:1549-1557.
15. Pulliam, L., Sun, B,. Rempel, H. (2004). Invasive chronic inflammatory monocyte phenotype in subjects with high hiv-1 viral load. J. Neuroimmunol. 157:93-98.
16. Sakaki, M., Hiroishi, K., Baba, T., Ito, T., Hirayama, Y., Saito, K., Tonoike, T., Kushima, M,. Imawari, M. (2008). Intrahepatic status of regulatory t cells in autoimmune liver diseases and chronic viral hepatitis. Hepatol Res. 38:354-361.
17. Sasaki, M., Ikeda, H., Yamaguchi, J., Nakada, S., Nakanuma, Y. (2008) Telomere shortening in the damaged small bile ducts in primary biliary cirrhosis reflects ongoing cellular senescence. Hepatology 48:186-195.
18. Strassburg, C. P., Manns, M. P. (2000). Autoimmune tests in primary biliary cirrhosis. Baillieres Best Pract. Res. Clin. Gastroenterol. 14:585-599.
19. Twaddell, W. S., Lefkowitch, J., Berk, P. D. (2008). Evolution from primary biliary cirrhosis to primary biliary cirrhosis/autoimmune hepatitis overlap syndrome. Semin. Liver Dis. 28:128-134.
20. van der Kuyl, A. C., van den Burg, R., Zorgdrager, F., Groot, F., Berkhout, B., Cornelissen, M. (2007). Sialoadhesin (cd169) expression in cd14+ cells is upregulated early after hiv-1 infection and increases during disease progression. PLoS One 2: e257.
21. Varki, A., Angata, T. (2006). Siglecs-The major subfamily of i-type lectins. Glycobiology 16:1R-27R.
22. Yoneyama, K., Yamazaki, M., Kogo, M., Kiuchi, Y., Shibata, M., Imawari, M. (2006). Prognostic factors of primary biliary cirrhosis detected by health screening. Minerva Gastroenterol. Dietol. 52:97-105.
23. York, M. R., Nagai, T., Mangini, A. J., Lemaire, R., van Seventer, J. M., Lafyatis, R. (2007). A macrophage marker, siglec-1, is increased on circulating monocytes in patients with systemic sclerosis and induced by type i interferons and toll-like receptor agonists. Arthritis Rheum. 56:1010-1020.