AUTO-MUTE: Web-based tools for predicting stability changes in proteins due to single amino acid replacements

Protein Engineering, Design and Selection

Volumn 23, Issue 8, 2010, Pages 683-687

  Masso, Majid ^a   Vaisman, Iosif I ^a  

^a GEORGE MASON UNIVERSITY   (United States)

Author keywords

knowledge based statistical potential; prediction; protein design; stability changes; structure based computational mutagenesis

Indexed keywords

COMPUTATIONAL MUTAGENESIS; DATA SETS; LINUX PLATFORM; MACHINE-LEARNING; MUTANT PROTEINS; NATIVE STRUCTURES; PROTEIN DESIGN; REGRESSION ALGORITHMS; SINGLE RESIDUE; STATISTICAL POTENTIAL; STRUCTURE-BASED; SUPERVISED CLASSIFICATION; TEST SETS; WEB-BASED TOOLS;

AMINO ACIDS; COMPUTER OPERATING SYSTEMS; CUTTING TOOLS; FORECASTING; KNOWLEDGE BASED SYSTEMS; MUTAGENESIS; ORGANIC ACIDS; PROTEINS; STABILITY;

STRUCTURAL DESIGN;

MUTANT PROTEIN; PROTEIN;

ACCURACY; AMINO ACID SUBSTITUTION; ANALYTIC METHOD; ARTICLE; CLIENT SERVER APPLICATION; MACHINE LEARNING; MUTAGENESIS; ONLINE SYSTEM; PREDICTIVE VALIDITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STABILITY; PROTEIN STRUCTURE; REGRESSION ANALYSIS; WEB BROWSER; ALGORITHM; ARTIFICIAL INTELLIGENCE; BIOLOGY; CHEMISTRY; COMPUTER PROGRAM; INTERNET; METABOLISM; PHYSICAL CHEMISTRY; PROCEDURES; THERMODYNAMICS;

ALGORITHMS; AMINO ACID SUBSTITUTION; ARTIFICIAL INTELLIGENCE; COMPUTATIONAL BIOLOGY; INTERNET; PHYSICOCHEMICAL PHENOMENA; PROTEIN STABILITY; PROTEINS; REGRESSION ANALYSIS; SOFTWARE; THERMODYNAMICS;

EID: 77954992105     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzq042     Document Type: Article

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