Antiosteoporotic effects and proteomic characterization of the target and mechanism of an Er-Xian decoction on osteoblastic UMR-106 and osteoclasts induced from RAW264.7

Molecules

Volumn 15, Issue 7, 2010, Pages 4695-4710

  Zhu, Zheng ^a,b,c   Xue, Li Ming ^b   Han, Ting ^b   Jiao, Lei ^b   Qin, Lu Ping ^b   Li, Yu Shan ^c   Zheng, Han Chen ^b   Zhang, Qiao Yan ^b  

^a CHINA MEDICAL UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Er Xian decoction; Osteoblast; Osteoclast; Osteoporosis; Proteomics

Indexed keywords

ER XIAN DECOCTION; ER-XIAN DECOCTION; HERBACEOUS AGENT;

ANIMAL; APOPTOSIS; ARTICLE; BONE REMODELING; CELL LINE; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECT; MACROPHAGE; METABOLISM; MOUSE; OSTEOBLAST; OSTEOCLAST; OSTEOPOROSIS; PATHOLOGY; PROTEIN FOLDING; PROTEOMICS;

ANIMALS; APOPTOSIS; BONE REMODELING; CELL LINE; CELL PROLIFERATION; DRUGS, CHINESE HERBAL; MACROPHAGES; MICE; OSTEOBLASTS; OSTEOCLASTS; OSTEOPOROSIS; PROTEIN FOLDING; PROTEOMICS;

EID: 77954977259     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules15074695     Document Type: Article

References (28)

1. Wang, C.H.; Zhang, Z.H.; Ma, J. Treatment of 50 cases of osteoporosis with Er-Xian Decoction. Shanxi J. Traditional Chin. Med. 1998, 19, 205.
2. Liu, Q.; Shi, J.R.; Yang, Y.; Fang, Z.Q.; Liang, S.H.; Guo, R.X. Effects on secretory function of rat gonad by Er-Xian Decoction and its disassembled prescriptions. China J. Chin. Mater. Med. 2005, 30, 1023-1026.
3. Nian, H.; Qin, L.P.; Zhang, Q.Y.; Zheng, H.C.; Yu, Y.; Huang, B.K. Antiosteoporotic activity of Er-Xian Decoction, a traditional Chinese herbal formula, in ovariectomized rats. J. Ethnopharmacol. 2006, 108, 96-102.
4. Qin, L.P.; Han, T.; Zhang, Q.Y.; Cao, D.P.; Nian, H.; Rahman, K.; Zheng, H.C. Antiosteoporotic chemical constituents from Er-Xian Decoction, a traditional Chinese herbal formula. J. Ethnopharmacol. 2008, 118, 271-279.
5. Xing, L.; Boyce, B.F. Regulation of apoptosis in osteoclasts and osteoblastic cells. Biochem. Biophs. Res. Commun. 2005, 328, 709-720.
6. Lindquist, S.; Craig, E.A. The heat-shock proteins. Annu. Rev. Genet. 1988, 22, 631-677.
7. Yang, J.; Shah, R.; Robling, A.G.; Templeton, E.; Yang, H.; Tracey, K.J.; Bidwell, J.P. HMGB1 is a bone-active cytokine. J. Cell. Physiol. 2008, 214,730-739.
8. Tchórzewski, M.; Krokowski, D.; Rzeski, W.; Issinger, O.G.; Grankowski, N. The subcellular distribution of the human ribosomal "stalk" components: P1, P2 and P0 proteins. Int. J. Biochem. Cell Biol. 2003, 35, 203-211.
9. Mariño-Ramírez, L.; Kann, M.G.; Shoemaker, B.A.; Landsman, D. Histone structure and nucleosome stability. Expert Rev. Proteomics 2005, 2, 719-729.
10. Merkwirth, C.; Langer, T. Prohibitin function within mitochondria: Essential roles for cell proliferation and cristae morphogenesis. Biochem. Biophs. Acta-Mol. Cell Res. 2009, 1793, 27-32.
11. Forrest, G.L.; Gonzalez, B. Carbonyl reductase. Chem. Biol. Interact. 2000, 129, 21-40.
12. Pedersen, P.L. Transport ATPases: structure, motors, mechanism and medicine: A brief overview. J. Bioenerg. Biomembr. 2005, 37, 349-357.
13. Valis, K.; Neubauerova, J.; Man, P.; Pompach, P.; Vohradsky, J.; Kovar, J. VDAC2 and aldolase A identified as membrane proteins of K562 cells with increased expression under iron deprivation. Mol. Cell. Biochem. 2008, 311, 225-231.
14. Ishizaki, H.; Togawa, A.; Tanaka-Okamoto, M.; Hori, K.; Nishimura, M.; Hamaguchi, A.; Imai, T.; Takai, Y.; Miyoshi, J. Defective chemokine-directed lymphocyte migration and development in the absence of Rho guanosine diphosphate-dissociation inhibitors alpha and beta. J. Immunol. 2006, 177, 8512-8521.
15. 2+. Exp. Cell Res. 1998, 242, 128-137.
16. Kim, S.H.; Jun, S.; Jang, H.S.; Lim, S.K. Identification of parathyroid hormone-regulated proteins in mouse bone marrow cells by proteomics. Biochem. Biophs. Res. Commun. 2005, 330, 423-429.
17. Binkert, C.; Demetriou, M.; Sukhu, B.; Szweras, M.; Tenenbaum, H.C.; Dennis, J.W. Regulation of osteogenesis by fetuin. J. Biol. Chem. 1999, 274, 28514-28520.
18. Veijola, J.; Pettersson, R.F. Transient association of calnexin and calreticulin with newly synthesized G1 and G2 glycoproteins of uukuniemi virus (family Bunyaviridae). J. Virol. 1999, 73, 6123-6127.
19. Delom, F.; Fessart, D.; Chevet, E. Regulation of calnexin sub-cellular localization modulates endoplasmic reticulum stress-induced apoptosis in MCF-7 cells. Apoptosis 2007, 12, 293-305.
20. Owen, T.A.; Aronow, M.; Shalhoub, V.; Barone, L.M.; Wilming, L.; Tassinari, M.S.; Kennedy, M.B.; Pockwinse, S.; Lian, J.B.; Stein, G.S. Progressive development of the rat osteoblast phenotype in vitro: reciprocal relationship in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix. J. Cell. Physiol. 1990, 143, 420-430.
21. Bradford, M.M. A rapid and sensitive method for the quantization of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72, 248-254.
22. Vignesh, R.C.; Sitta Djody, S.; Jayasudha, E.; Gopalakrishnan, V.; Ilangovan, R.; Balaganesh, M.; Veni, S.; Sridhar, M.; Srinivasan, N. Effect of ethanol on human osteosarcoma cell proliferation, differentiation and mineralization. Toxicology 2006, 220, 63-70.
23. Collin-Osdoby, P.; Yu, X.; Zheng, H; Osdoby, P. RANKL-mediated osteoclast formation from murine RAW 264.7 cells. Methods Mol. Med. 2003, 80, 153-166.
24. Katherine, N.W.; Gabriela, M.; Wade, E.H.; Clifford, M.T.; Timothy, J.H.; Ying, X.; Christine, L.H.; Nikki, R.D; Audrey, G.W.; David, E.F. Linkage of M-CSF Signaling to Mitf, TFE3, and the Osteoclast Defect in Mitfmi/mi Mice. Mol. Cell. 2001, 8, 749-758.
25. Tibor, B. A simple Azo-Dye method for histochemical demonstration of acid phosphatase. Nature 1960, 187, 248-249.
26. Pfeilschifter, J.; Chenu, C.; Bird, A.; Mundy, G.R.; Roodman, G.D. Interleukin-1 and tumor necrosis factor stimulate the formation of human osteoclastlike cells in vitro. J. Bone Min. Res. 1989, 4, 113-118.
27. Zambonin, Z.A.; Teti, A.; Primavera, M.V. Isolated osteoclasts in primary culture: first observation on structure and survival in culture media. Anat. Embryol. 1982, 165, 405-413.
28. Zhengm, X.J.; Hong, L.L.; Shi, L.X.; Guo, J.Q.; Sun, Z. Zhou, J.Y. Proteomic analysis of host cells infected with infectious bursal disease virus. Mol. Cell. Proteomics 2008, 7, 612-625.