Acellular cardiac extracellular matrix as a scaffold for tissue engineering: In vitro cell support, remodeling, and biocompatibility

Tissue Engineering - Part C: Methods

Volumn 16, Issue 4, 2010, Pages 671-683

  Eitan, Yuval ^a   Sarig, Udi ^a   Dahan, Nitsan ^a   MacHluf, Marcelle ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; BIOCOMPATIBILITY; BIOMECHANICS; BLOOD VESSELS; CELL CULTURE; DURABILITY; ENZYME ACTIVITY; ENZYME INHIBITION; FIBROBLASTS; HEART; MECHANICAL PROPERTIES; MECHANICAL TESTING; POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; STEM CELLS; TISSUE; TISSUE ENGINEERING;

ACELLULAR SCAFFOLDS; CARDIAC MARKERS; CARDIAC TISSUE ENGINEERING; CARDIAC TISSUES; CARDIOMYOCYTES; CELL DENSITY; CONTROL-CELL; DAYS AFTER SEEDING; DECELLULARIZATION; EXTRACELLULAR MATRICES; GLYCOSAMINOGLYCANS; IMMUNOFLUORESCENT STAINING; IN-VITRO; MATRIX METALLOPROTEINASE-2; MESENCHYMAL STEM CELL; METALLOPROTEINASES; MYOCYTES; REAL-TIME POLYMERASE CHAIN REACTION; SEEDED CELLS; TISSUE INHIBITOR; TROPONIN I;

SCAFFOLDS;

BIOMATERIAL; COLLAGEN; FIBRONECTIN; TISSUE SCAFFOLD;

ANIMAL; ARTICLE; BIOASSAY; BIOMECHANICS; CELL SHAPE; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG EFFECT; EXTRACELLULAR MATRIX; FEMALE; FIBROBLAST; HEART CONTRACTION; HEART MUSCLE; HEART MUSCLE CELL; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; MACROPHAGE ACTIVATION; MESENCHYMAL STEM CELL; METABOLISM; METHODOLOGY; MOUSE; RAT; REPRODUCIBILITY; SHEEP; SWINE; TISSUE ENGINEERING; ULTRASTRUCTURE;

ANIMALS; BIOCOMPATIBLE MATERIALS; BIOLOGICAL ASSAY; BIOMECHANICS; CELL SHAPE; CELL SURVIVAL; COLLAGEN; EXTRACELLULAR MATRIX; FEMALE; FIBROBLASTS; FIBRONECTINS; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; MACROPHAGE ACTIVATION; MESENCHYMAL STEM CELLS; MICE; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; RATS; REPRODUCIBILITY OF RESULTS; SHEEP; SUS SCROFA; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 77954968089     PISSN: 19373384     EISSN: 19373392     Source Type: Journal    
DOI: 10.1089/ten.tec.2009.0111     Document Type: Article

References (52)

1. Jawad, H., Ali, N.N., Lyon, A.R., Chen, Q.Z., Harding, S.E., and Boccaccini, A.R. Myocardial tissue engineering: a review. J Tissue Eng Regen Med 1, 327, 2007.
2. Leor, J., and Alexander, B. Editorial: regeneration hope to grow a new heart muscle. Heart Fail Rev 8, 197, 2003.
3. Leor, J., Landa, N., and Cohen, S. Renovation of the injured heart with myocardial tissue engineering. Expert Rev Car-diovasc Ther 4, 239, 2006.
4. Zimmermann, W.H., Didie, M., Doker, S., Melnychenko, I., Naito, H., Rogge, C., Tiburcy, M., and Eschenhagen, T. Heart muscle engineering: an update on cardiac muscle replacement therapy. Cardiovasc Res 71, 419, 2006.
5. Jawad, H., Lyon, A.R., Harding, S.E., Ali, N.N., and Boc-caccini, A.R. Myocardial tissue engineering. Br Med Bull 87, 31, 2008.
6. Zimmermann, W.H., and Eschenhagen, T. Cardiac tissue engineering for replacement therapy. Heart Fail Rev 8, 259, 2003.
7. Ozawa, T., Mickle, D.A., Weisel, R.D., Koyama, N., Ozawa, S., and Li, R.K. Optimal biomaterial for creation of autolo-gous cardiac grafts. Circulation 106, I176, 2002.
8. Davis, M.E., Hsieh, P.C., Grodzinsky, A.J., and Lee, R.T. Custom design of the cardiac microenvironment with bio-materials. Circ Res 97, 8, 2005.
9. Leor, J., Amsalem, Y., and Cohen, S. Cells, scaffolds, and molecules for myocardial tissue engineering. Pharmacol Ther 105, 151, 2005.
10. Roccio, M., Goumans, M.J., Sluijter, J.P., and Doevendans, P.A. Stem cell sources for cardiac regeneration. Panminerva Med 50, 19, 2008.
11. Schuleri, K.H., Boyle, A.J., and Hare, J.M. Mesenchymal stem cells for cardiac regenerative therapy. Handb Exp Pharmacol 180, 195, 2007.
12. Pallante, B.A., and Edelberg, J.M. Cell sources for cardiac regeneration-which cells and why. Am Heart Hosp J 4, 95, 2006.
13. Fuchs, J.R., Nasseri, B.A., Vacanti, J.P., and Fauza, D.O. Postnatal myocardial augmentation with skeletal myoblast-based fetal tissue engineering. Surgery 140, 100, 2006.
14. Siepe, M., Giraud, M.N., Liljensten, E., Nydegger, U., Menasche, P., Carrel, T., and Tevaearai, H.T. Construction of skeletal myoblast-based polyurethane scaffolds for myocar-dial repair. Artif Organs 31, 425, 2007.
15. Simpson, D., Liu, H., Fan, T.H., Nerem, R., and Dudley, S.C., Jr. A tissue engineering approach to progenitor cell delivery results in significant cell engraftment and improved myo-cardial remodeling. Stem Cells 25, 2350, 2007.
16. Xiang, Z., Liao, R., Kelly, M.S., and Spector, M. Collagen-GAG scaffolds grafted onto myocardial infarcts in a rat model: a delivery vehicle for mesenchymal stem cells. Tissue Eng 12, 2467, 2006.
17. Fukuda, K. Application of mesenchymal stem cells for the regeneration of cardiomyocyte and its use for cell transplantation therapy. Hum Cell 16, 83, 2003.
18. Fromstein, J.D., Zandstra, P.W., Alperin, C., Rockwood, D., Rabolt, J.F., and Woodhouse, K.A. Seeding bioreactor-produced embryonic stem cell-derived cardiomyocytes on different porous, degradable, polyurethane scaffolds reveals the effect of scaffold architecture on cell morphology. Tissue Eng Part A 14, 369, 2008.
19. Caspi, O., Lesman, A., Basevitch, Y., Gepstein, A., Arbel, G., Habib, I.H., Gepstein, L., and Levenberg, S. Tissue engineering of vascularized cardiac muscle from human embryonic stem cells. Circ Res 100, 263, 2007.
20. Zimmermann, W.H., and Eschenhagen, T. Embryonic stem cells for cardiac muscle engineering. Trends Cardiovasc Med 17, 134, 2007.
21. Costa, K.D., Lee, E.J., and Holmes, J.W. Creating alignment and anisotropy in engineered heart tissue: role of boundary conditions in a model three-dimensional culture system. Tissue Eng 9, 567, 2003.
22. Au, H.T., Cheng, I., Chowdhury, M.F., and Radisic, M. Interactive effects of surface topography and pulsatile electrical field stimulation on orientation and elongation of fibroblasts and cardiomyocytes. Biomaterials 28, 4277, 2007.
23. Matsubayashi, K., Fedak, P.W., Mickle, D.A., Weisel, R.D., Ozawa, T., and Li, R.K. Improved left ventricular aneurysm repair with bioengineered vascular smooth muscle grafts. Circulation 108 Suppl 1, II219, 2003.
24. Schmidt, D., Mol, A., Neuenschwander, S., Breymann, C., Gossi, M., Zund, G., Turina, M., and Hoerstrup, S.P. Living patches engineered from human umbilical cord derived fibroblasts and endothelial progenitor cells. Eur J Cardi-othorac Surg 27, 795, 2005.
25. Sales, V.L., Mettler, B.A., Lopez-Ilasaca, M., Johnson, J.A., Jr., and Mayer, J.E., Jr. Endothelial progenitor and mesenchymal stem cell-derived cells persist in tissue-engineered patch in vivo: application of green and red fluorescent protein-expressing retroviral vector. Tissue Eng 13, 525, 2007.
26. Messina, E., De Angelis, L., Frati, G., Morrone, S., Chimenti, S., Fiordaliso, F., Salio, M., Battaglia, M., Latronico, M.V., Coletta, M., Vivarelli, E., Frati, L., Cossu, G., and Giaco-mello, A. Isolation and expansion of adult cardiac stem cells from human and murine heart. Circ Res 95, 911, 2004.
27. Barile, L., Messina, E., Giacomello, A., and Marban, E. Endogenous cardiac stem cells. Prog Cardiovasc Dis 50, 31, 2007.
28. Badylak, S.F. The extracellular matrix as a biologic scaffold material. Biomaterials 28, 3587, 2007.
29. Gilbert, T.W., Sellaro, T.L., and Badylak, S.F. Decellulariza-tion of tissues and organs. Biomaterials 27, 3675, 2006.
30. Badylak, S.F. Xenogeneic extracellular matrix as a scaffold for tissue reconstruction. Transpl Immunol 12, 367, 2004.
31. Beattie, A.J., Gilbert, T.W., Guyot, J.P., Yates, A.J., and Badylak, S.F. Chemoattraction of progenitor cells by remodeling extracellular matrix scaffolds. Tissue Eng Part A 15, 1119, 2009.
32. Kochupura, P.V., Azeloglu, E.U., Kelly, D.J., Doronin, S.V., Badylak, S.F., Krukenkamp, I.B., Cohen, I.S., and Gaudette, G.R. Tissue-engineered myocardial patch derived from extracellular matrix provides regional mechanical function. Circulation 112, I144, 2005.
33. Robinson, K.A., Li, J., Mathison, M., Redkar, A., Cui, J., Chronos, N.A., Matheny, R.G., and Badylak, S.F. Extracellular matrix scaffold for cardiac repair. Circulation 112, I135, 2005.
34. Cui, J., Li, J., Mathison, M., Tondato, F., Mulkey, S.P., Micko, C., Chronos, N.A., and Robinson, K.A. A clinically relevant large-animal model for evaluation of tissue-engineered cardiac surgical patch materials. Cardiovasc Revasc Med 6, 113, 2005.
35. Badylak, S.F., Kochupura, P.V., Cohen, I.S., Doronin, S.V., Saltman, A.E., Gilbert, T.W., Kelly, D.J., Ignotz, R.A., and Gaudette, G.R. The use of extracellular matrix as an inductive scaffold for the partial replacement of functional myocardium. Cell Transplant 15 Suppl 1, S29, 2006.
36. Ota, T., Gilbert, T.W., Badylak, S.F., Schwartzman, D., and Zenati, M.A. Electromechanical characterization of a tissue-engineered myocardial patch derived from extracellular matrix. J Thorac Cardiovasc Surg 133, 979, 2007.
37. Badylak, S.F., Freytes, D.O., and Gilbert, T.W. Extracellular matrix as a biological scaffold material: structure and function. Acta Biomater 5, 1, 2009.
38. Ott, H.C., Matthiesen, T.S., Goh, S.K., Black, L.D., Kren, S.M., Netoff, T.I., and Taylor, D.A. Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart. Nat Med 14, 213, 2008.
39. Zeevi-Levin, N., Barac, Y.D., Reisner, Y., Reiter, I., Yaniv, G., Meiry, G., Abassi, Z., Kostin, S., Schaper, J., Rosen, M.R., Resnick, N., and Binah, O. Gap junctional remodeling by hypoxia in cultured neonatal rat ventricular myocytes. Cardiovasc Res 66, 64, 2005.
40. Kehat, I., Khimovich, L., Caspi, O., Gepstein, A., Shofti, R., Arbel, G., Huber, I., Satin, J., Itskovitz-Eldor, J., and Gepstein, L. Electromechanical integration of cardiomyo-cytes derived from human embryonic stem cells. Nat Bio-technol 22, 1282, 2004.
41. Bergman, I., and Loxley, R. Two improved and simplified methods for the spectrophotometric determination of hy-droxyproline. Anal Chem 35, 1961, 1963.
42. Carrino, D.A., Arias, J.L., and Caplan, A.I. A spectrophoto-metric modification of a sensitive densitometric Safranin O assay for glycosaminoglycans. Biochem Int 24, 485, 1991.
43. Pauschinger, M., Doerner, A., Remppis, A., Tannhauser, R., Kuhl, U., and Schultheiss, H.P. Differential myocardial abundance of collagen type I and type III mRNA in dilated cardiomyopathy: effects of myocardial inflammation. Car-diovasc Res 37, 123, 1998.
44. Samouillan, V., Dandurand-Lods, J., Lamure, A., Maurel, E., Lacabanne, C., Gerosa, G., Venturini, A., Casarotto, D., Gherardini, L., and Spina, M. Thermal analysis characterization of aortic tissues for cardiac valve bioprostheses. J Biomed Mater Res 46, 531, 1999.
45. Radisic, M., Park, H., Chen, F., Salazar-Lazzaro, J.E., Wang, Y., Dennis, R., Langer, R., Freed, L.E., and Vunjak-Novakovic, G. Biomimetic approach to cardiac tissue engineering: oxygen carriers and channeled scaffolds. Tissue Eng 12, 2077, 2006.
46. Fukuda, K. Development of regenerative cardiomyocytes from mesenchymal stem cells for cardiovascular tissue engineering. Artif Organs 25, 187, 2001.
47. Dreger, S.A., Thomas, P., Sachlos, E., Chester, A.H., Czer-nuszka, J.T., Taylor, P.M., and Yacoub, M.H. Potential for synthesis and degradation of extracellular matrix proteins by valve interstitial cells seeded onto collagen scaffolds. Tissue Eng 12, 2533, 2006.
48. Gilbert, T.W., Stewart-Akers, A.M., Sydeski, J., Nguyen, T.D., Badylak, S.F., and Woo, S.L. Gene expression by fibroblasts seeded on small intestinal submucosa and subjected to cyclic stretching. Tissue Eng 13, 1313, 2007.
49. Gupta, V., Werdenberg, J.A., Blevins, T.L., and Grande-Allen, K.J. Synthesis of glycosaminoglycans in differently loaded regions of collagen gels seeded with valvular interstitial cells. Tissue Eng 13, 41, 2007.
50. Lai, P.H., Chang, Y., Chen, S.C., Wang, C.C., Liang, H.C., Chang, W.C., and Sung, H.W. Acellular biological tissues containing inherent glycosaminoglycans for loading basic fibroblast growth factor promote angiogenesis and tissue regeneration. Tissue Eng 12, 2499, 2006.
51. Feng, Z., Matsumoto, T., and Nakamura, T. Measurements of the mechanical properties of contracted collagen gels populated with rat fibroblasts or cardiomyocytes. J Artif Organs 6, 192, 2003.
52. Badylak, S.F., and Gilbert, T.W. Immune response to biologic scaffold materials. Semin Immunol 20, 109, 2008.