Estrogen administration during superovulation increases oocyte quality and expressions of vascular endothelial growth factor and nitric oxide synthase in the ovary

Journal of Obstetrics and Gynaecology Research

Volumn 36, Issue 4, 2010, Pages 789-795

  Ha, Choong Sik ^a   Joo, Bo Sun ^b   Kim, Seung Chul ^a   Joo, Jong Kil ^a   Kim, Hwi Gon ^a   Lee, Kyu Sup ^a  

^a Pusan National University School of Medicine   (South Korea)

^b Good Moonhwa Hospital   (South Korea)

Author keywords

eNOS; estrogen; oocyte quality; ovarian angiogenesis; VEGF

Indexed keywords

CHORIONIC GONADOTROPIN; ESTRADIOL; NITRIC OXIDE SYNTHASE; SERIC GONADOTROPIN; VASCULAR ENDOTHELIAL GROWTH INHIBITOR; ENDOTHELIAL NITRIC OXIDE SYNTHASE; VASCULOTROPIN A;

ANGIOGENESIS; ANIMAL EXPERIMENT; ARTICLE; BLASTOCYST; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; OOCYTE; OVARY; PROTEIN EXPRESSION; SUPEROVULATION; WESTERN BLOTTING; ZYGOTE; ANALYSIS OF VARIANCE; ANIMAL; DRUG EFFECTS; EMBRYO CULTURE; METABOLISM;

ANALYSIS OF VARIANCE; ANIMALS; BLASTOCYST; BLOTTING, WESTERN; EMBRYO CULTURE TECHNIQUES; ESTRADIOL; FEMALE; GONADOTROPINS, EQUINE; IMMUNOHISTOCHEMISTRY; MICE; NITRIC OXIDE SYNTHASE TYPE III; OOCYTES; OVARY; SUPEROVULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 77954932773     PISSN: 13418076     EISSN: 14470756     Source Type: Journal    
DOI: 10.1111/j.1447-0756.2010.01212.x     Document Type: Article

References (32)

1. Geva E, Jaffe RB. Role of vascular endothelial growth factor in ovarian physiology and pathology. Fertil Steril 2000 74 : 429 438.
2. Hazzards TM, Xua F, Stouffer RL. Injection of soluble vascular endothelial growth factor receptor 1 into the preovulatory follicle disrupts ovulation and subsequent luteal function in Rhesus monkey. Biol Reprod 2002 67 : 1305 1312.
3. Fraser HM, Wilson H, Rudge JS, Wiegand SJ. Single injections of vascular endothelial growth factor trap block ovulation in the macaque and produce a prolonged, dose-related suppression of ovarian function. J Clin Endocrinol Metab 2005 90 : 1114 1122.
4. Wulff C, Wilson H, Wiegand SJ, Rudge JS, Fraser HM. Prevention of thecal angiogenesis, antral follicular growth, and ovulation in primate by treatment with vascular endothelial growth factor trap R1R2. Endocrinology 2002 43 : 2797 2807.
5. Shimizu T, Jiang JY, Iijima K et al. Induction of follicular development by direct single injection of vascular endothelial growth factor gene fragments into the ovary of miniature gilts. Biol Reprod 2003 69 : 1388 1393.
6. Danforth DR, Arbogast LK, Ghosh S, Dickerman A, Rofagha R, Friedman CI. Vascular endothelial growth factor stimulates preantral follicle growth in the rat ovary. Biol Reprod 2003 68 : 1736 1741.
7. Iijima K, Jiang JY, Shimazu T, Sasada H, Sato E. Acceleration of follicular development by administration of vascular endothelial growth factor in cycling female rats. J Reprod Dev 2005 51 : 161 168.
8. Jablonka-Shariff A, Olson LM. The role of nitric oxide in oocyte meiotic maturation and ovulation: Meiotic abnormalities of endothelial nitric oxide synthase knock-out mouse oocytes. Endocrinology 1998 139 : 2944 2954.
9. Sengoku K, Takuma N, Horikawa M et al. Requirement of nitric oxide for murine oocyte maturation, embryo development, and trophoblast outgrowth in vitro. Mol Reprod Dev 2001 58 : 262 268.
10. Murohara T, Horowitz JR, Silver M et al. Vascular endothelial growth factor/vascular permeability factor enhances vascular permeability via nitric oxide and prostacyclin. Circulation 1998 97 : 99 107.
11. Weiner CP, Lizasoain I, Baylis SA, Knowles RG, Charles IG, Moncada S. Induction of calcium-dependent nitric oxide synthases by sex hormones. Proc Natl Acad Sci U S A 1994 91 : 5212 5216. (Pubitemid 24177823)
12. Kolibianakis EM, Papanikolaou EG, Fatemi HM, Devroey P. Estrogen and folliculogenesis: Is one necessary for the other? Curr Opin Obstet Gynecol 2005 17 : 249 253.
13. Losordo DW, Isner JM. Estrogen and angiogenesis: A review. Arterioscler Thromb Vasc Biol 2001 21 : 6 12.
14. Mueller MD, Vigne JL, Minchenko A, Lebovic DI, Leitman DC, Taylor RN. Regulation of vascular endothelial growth factor (VEGF) gene transcription by estrogen receptors alpha and beta. Proc Natl Acad Sci U S A 2000 97 : 10972 10977.
15. Niklaus AL, Aberdeen GW, Babischkin JS, Pepe GJ, Albrecht ED. Effect of estrogen on vascular endothelial growth/permeability factor expression by glandular epithelial and stromal cells in the baboon endometrium. Biol Reprod 2003 68 : 1997 2004.
16. Nayak NR, Brenner RM. Vascular proliferation and vascular endothelial growth factor expression in the rhesus macaque endometrium. J Clin Endocrinol Metab 2002 87 : 1845 1855.
17. Latin-Hermoso RL, Rosenfeld CR, Yuhamnna IS, German Z, Chen Z, Shaul PW. Estrogen acutely stimulates nitric oxide synthase activity in fetal pulmonary artery endothelium. Am J Physiol 1997 273 : L119 L126.
18. Rosselli M, Keller PJ, Dubey RK. Role of nitric oxide in the biology, physiology, and pathophysiology of reproduction. Hum Reprod Update 1998 4 : 3 24.
19. Mitchell LM, Kennedy CR, Hartshorne GM. Expression of nitric oxide synthase and effect of substrate manipulation of the nitric oxide pathway in mouse ovarian follicles. Hum Reprod 2004 19 : 30 40.
20. Mattioli M, Barboni B, Turriani M et al. Follicle activation involves vascular endothelial growth factor production and increased blood vessel extension. Biol Reprod 2001 65 : 1014 1019.
21. Shima DT, Kuroki M, Deutsch U, Ng YS, Adamis AP, D'Amore PA. The mouse gene for vascular endothelial growth factor. Genomic structure, definition of the transcriptional unit, and characterization of transcriptional and post-transcriptional regulatory sequences. J Biol Chem 1996 271 : 3877 3883.
22. Burchardt M, Burchardt T, Chen MW et al. Expression of messenger ribonucleic acid splice variants for vascular endothelial growth factor in the penis of adult rats and humans. Biol Reprod 1999 60 : 398 404.
23. Redmer CA, Reynolds LP. Angiogenesis in the ovary. Rev Reprod 1996 1 : 182 192.
24. Fraser HM. Regulation of the ovarian follicular vasculature. Reprod Biol Endocrinol 2006 4 : 18.
25. Bonello N, McKie K, Jasper M et al. Inhibition of nitric oxide: Effects on interleukin-1 beta-enhanced ovulation rate, steroid hormones, and ovarian leukocyte distribution at ovulation in the rat. Biol Reprod 1996 54 : 436 445.
26. Adashi EY. Clomiphene citrate: Mechanism(s) and site(s) of action - a hypothesis revisited. Fertil Steril 1984 42 : 331 344.
27. Dickey RP, Holtkamp DE. Development, pharmacology and clinical experience with clomiphene citrate. Hum Reprod Update 1996 2 : 483 506.
28. Childs GV, Iruthayanathan M, Akhter N, Johnson BW. Estrogen mediated cross talk between the ovary and pituitary somatotrope. Pre-ovulatory support for reproductive activity. Mol Cell Endocrinol 2006 247 : 60 63.
29. Stouffer RL, Martinez-Chequer JC, Molskness TA, Xu F, Hazzard TM. Regulation and action of angiogenic factors in the primate ovary. Arch Med Res 2001 32 : 567 575.
30. Gómez R, Simón C, Remohí J, Pellicer A. Administration of moderate and high doses of gonadotropins to female rats increases ovarian vascular endothelial growth factor (VEGF) and VEGF receptor-2 expression that is associated to vascular hyperpermeability. Biol Reprod 2003 68 : 2164 2171.
31. Joo BS, Park SH, An BM, Kim KS, Moon SE, Moon HS. Serum estradiol levels during controlled ovarian hyperstimulation influence the pregnancy outcome of in vitro fertilization in a concentration-dependent manner. Fertil Steril 2010 93 : 442 446.
32. Ng EH, Chan CC, Tang OS, Yeung WS, Ho PC. Factors affecting endometrial and subendometrial blood flow measured by three-dimensional power Doppler ultrasound during IVF treatment. Hum Reprod 2006 21 : 1062 1069.