Mayamycin, a cytotoxic polyketide from a streptomyces strain isolated from the marine sponge halichondria panicea

Journal of Natural Products

Volumn 73, Issue 7, 2010, Pages 1309-1312

  Schneemann, Imke ^a   Kajahn, Inga ^a   Ohlendorf, Birgit ^a   Zinecker, Heidi ^a   Erhard, Arlette ^a   Nagel, Kerstin ^a   Wiese, Jutta ^a   Imhoff, Johannes F ^a  

^a GEOMAR HELMHOLTZ CENTRE FOR OCEAN RESEARCH KIEL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BENZ[A]ANTHRACENE DERIVATIVE; CYCLOHEXIMIDE; CYTOTOXIC AGENT; MAYAMYCIN; POLYKETIDE; POLYKETIDE SYNTHASE; TAMOXIFEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; BIOSYNTHESIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOTOXICITY; DRUG MANUFACTURE; GENETIC ANALYSIS; HALICHONDRIA PANICEA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC 50; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; SPONGE (PORIFERA); STREPTOMYCES; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; BENZ(A)ANTHRACENES; DRUG RESISTANCE, BACTERIAL; DRUG SCREENING ASSAYS, ANTITUMOR; HT29 CELLS; HUMANS; MARINE BIOLOGY; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; POLYKETIDE SYNTHASES; PORIFERA; STEREOISOMERISM; STREPTOMYCES;

HALICHONDRIA PANICEA; STREPTOMYCES; STREPTOMYCES SP.;

EID: 77954930640     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np100135b     Document Type: Article

References (19)

1. Fenical, W. and Jensen, P. R. Nat. Chem. Biol. 2006, 2, 666-673
2. Schneemann, I., Nagel, K., Kajahn, I., Labes, A., Wiese, J., and Imhoff, J. F. Appl. Environ. Microbiol. 2010, 76, 3702-3714
3. Han, L., Yang, K., Ramalingam, E., Mosher, R. H., and Vining, L. C. Microbiology 1994, 140, 3379-3389
4. Mitova, M. I., Lang, G., Wiese, J., and Imhoff, J. F. J. Nat. Prod. 2008, 71, 824-827
5. Gould, S. J., Cheng, X.-C., and Halley, K. J. Am. Chem. Soc. 1992, 114, 10066-10068
6. Rasmussen, R. R., Nuss, M. E., Scherr, M. H., Mueller, S. L., McAlpine, J. B., and Mitscher, L. A. J. Antibiot. 1986, 39, 1515-1526
7. Kinumaki, A. and Suzuki, M. J. Antibiot. 1972, 25, 480-482
8. Léo, P.-M., Morin, C., and Philouze, C. Org. Lett. 2002, 4, 2711-2714
9. Martin, G. D. A., Tan, L. T., Jensen, P. R., Dimayuga, R. E., Fairchild, C. R., Raventos-Suarez, C., and Fenical, W. J. Nat. Prod. 2007, 70, 1406-1409
10. Okabe, T., Suda, H., Sato, F., and Okanishi, M. Japan Patent 1988-317866, 1990.
11. Etho, H., Iguchi, M., Nagasawa, T., Tani, Y., Yamada, H., and Fukami, H. J. Antibiot. 1987, 51, 1819-1824
12. Uesato, S., Tokunaga, T., Mizuno, Y., Fujioka, H., Kada, S., and Kuwajima, H. J. Nat. Prod. 2000, 63, 787-792
13. Rohr, J. and Thiericke, R. Nat. Prod. Rep. 1992, 9, 103-137
14. Metsä-Ketelä, M., Salo, V., Halo, L., Hautala, A., Hakala, J., Mäntsälä, P., and Ylihonko, K. FEMS Microbiol. Lett. 1999, 180, 1-6
15. Thiel, V., Neulinger, S. C., Staufenberger, T., Schmaljohann, R., and Imhoff, J. F. FEMS Microbiol. Ecol. 2007, 59, 47-63
16. Altschul, S. F., Gish, W., Miller, W., Myers, E. W., and Lipman, D. J. J. Mol. Biol. 1990, 215, 403-410
17. Collins, L. and Franzblau, S. G. Antimicrob. Agents Chemother. 1997, 41, 1004-1009
18. Sahly, H., Schubert, S., Harder, J., Rautenberg, P., Ullmann, U., Schröder, J., and Podschun, R. Antimicrob. Agents Chemother. 2003, 47, 1739-1741
19. Dengler, W. A., Schulte, J., Berger, D. P., Mertelsmann, R., and Fiebig, H. H. Anticancer Drugs 1995, 6, 522-532