Racial disparity in A1C independent of mean blood glucose in children with type 1 diabetes

Diabetes Care

Volumn 33, Issue 5, 2010, Pages 1025-1027

  Kamps, Jodi L ^a,b   Hempe, James M ^b,c   Chalew, Stuart A ^a,b,c  

^a CHILDREN S HOSPITAL   (United States)

^b LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c The Research Institute for Children at Children's Hospital New Orleans   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; BIOLOGICAL MARKER; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN;

ADOLESCENT; AFRICAN AMERICAN; AGE DETERMINATION; ARTICLE; CAUCASIAN; CHILD; CONTROLLED STUDY; DISEASE DURATION; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD; RACE DIFFERENCE; SCHOOL CHILD; SCORING SYSTEM; ANALYSIS OF VARIANCE; COMPARATIVE STUDY; ETHNOLOGY; METABOLISM; PREDICTION AND FORECASTING; RISK FACTOR; STATISTICS;

ADOLESCENT; AFRICAN AMERICANS; ANALYSIS OF VARIANCE; BIOLOGICAL MARKERS; BLOOD GLUCOSE; CHILD; DIABETES MELLITUS, TYPE 1; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; MALE; PREDICTIVE VALUE OF TESTS; RISK FACTORS;

EID: 77954922283     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc09-1440     Document Type: Article

References (15)

1. Hempe JM, Gomez R, McCarter RJ Jr, Chalew SA. High and low hemoglobin glycation phenotypes in type 1 diabetes: a challenge for interpretation of glycemic control. J Diabetes Complications 2002;16:313-320
2. McCarter RJ, Hempe JM, Gomez R, Chalew SA. Biological variation in HbA1c predicts risk of retinopathy and nephropathy in type 1 diabetes. Diabetes Care 2004;27:1259-1264
3. McCarter RJ, Hempe JM, Chalew SA. Mean blood glucose and biological variation have greater influence on HbA1c levels than glucose instability: an analysis of data from the Diabetes Control and Complications Trial. Diabetes Care 2006;29:352-355
4. Kirk JK, D'AgostinoRBJr, Bell RA, Passmore LV, Bonds DE, Karter AJ, Narayan KM. Disparities in HbA1c levels between African-American and non-Hispanic white adults with diabetes: a meta-analysis. Diabetes Care 2006;29:2130-2136
5. Kirk JK, Passmore LV, Bell RA, Narayan KM, D'Agostino RB Jr, Arcury TA, Quandt SA. Disparities in HbA1c levels between Hispanic and non-Hispanic white adults with diabetes: a meta-analysis. Diabetes Care 2008;31:240-246
6. Herman WH, Dungan KM, Wolffenbuttel BHR, Buse JB, Fahrbach JL, Jiang H, Martin S. Racial and ethnic differences in mean plasma glucose, hemoglobin A1c, and 1,5-anhydroglucitol in over 2000 patients with type 2 diabetes. J Clin Endorinol Metab 2009;94:1689-1694
7. Herman WH, Ma Y, Uwaifo G, Haffner S, Kahn SE, Horton ES, Lachin JM, Montez MG, Brenneman T, Barrett-Connor E, the Diabetes Prevention Program Research Group. Differences in A1C by race and ethnicity among patients with impaired glucose tolerance in the Diabetes Prevention Program. Diabetes Care 2007;30:2453-2457
8. Selvin E, Zhu H, Brancati FL. Elevated A1C in adults without a history of diabetes in the U.S. Diabetes Care 2009;32:828-833
9. Chalew SA, Gomez R, Butler A, Hempe J, Compton T, Mercante D, Rao J, Vargas A. Predictors of glycemic control in children with type 1 diabetes: the importance of race. J Diabetes Complications 2000;14:71-77
10. Saaddine JB, Fagot-Campagna A, Rolka D, Narayan KM, Geiss L, Eberhardt M, Flegal KM. Distribution of HbA1c levels for children and young adults in the U.S.: Third National Health and Nutrition Examination Survey. Diabetes Care 2002;25:1326-1330
11. Little RR, Rohlfing CL, Wiedmeyer HM, Myers GL, Sacks DB, Goldstein DE, the NGSP Steering Committee. The National Glycohemoglobin Standardization Program: a five-year progress report. Clin Chem 2001;47:1985-1992
12. Soros AA, Chalew SA, McCarter RJ, Shepard R, Hempe JM. Hemoglobin glycation index: a robust measure of hemoglobin A1c bias in pediatric type 1 diabetes patients. Pediatr Diabetes. 18 January 2010 [Epub ahead of print]
13. Gould BJ, Davie SJ, Yudkin JS. Investigation of the mechanism underlying the variability of glycated haemoglobin in non-diabetic subjects not related to glycaemia. Clin Chim Acta 1997;260:49-64
14. Delpierre G, Collard F, Fortpied J, Van Schaftingen E. Fructosamine 3-kinase is involved in intracellular deglycation pathway in human erythrocytes. Biochem J 2002;365:801-808
15. Arfken CL, Reno PL, Santiago JV, Klein R. Development of proliferative diabetic retinopathy in African-Americans and whites with type 1 diabetes. Diabetes Care 1998;21:792-795