Enzymatic synthesis of uracil glucuronide, labeling with 125/131I, and in vitro evaluation on adenocarcinoma cells

Cancer Biotherapy and Radiopharmaceuticals

Volumn 25, Issue 3, 2010, Pages 335-344

  Medine, Ilker Emin ^a   Unak, Perihan ^a   Sakarya, Serhan ^b   Toksöz, Feriha ^a  

^a EGE UNIVERSITY   (Turkey)

^b ADNAN MENDERES UNIVERSITY   (Turkey)

Author keywords

125I; 131I; adenocarcinoma cell lines; UDP glucuronidase; uracil glucuronide

Indexed keywords

GLUCURONIDE; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; URACIL DERIVATIVE; URACIL N GLUCURONIDE I 125; URACIL N GLUCURONIDE I 131; URACIL O GLUCURONIDE I 125; URACIL O GLUCURONIDE I 131; URIDINE DIPHOSPHATE;

ARTICLE; CANCER CELL CULTURE; CELL TYPE; CONTROLLED STUDY; DRUG SCREENING; DRUG STABILITY; DRUG SYNTHESIS; ENZYME SYNTHESIS; GASTROINTESTINAL CARCINOMA; GLUCURONIDATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTESTINE EPITHELIUM CELL; ISOTOPE LABELING; MASS SPECTROMETRY; MICROSOME; PRIORITY JOURNAL;

ADENOCARCINOMA; CELL LINE; CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLUCURONIDASE; GLUCURONIDES; GLUCURONOSYLTRANSFERASE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; IODINE RADIOISOTOPES; ISOTOPE LABELING; MICROSOMES; MOLECULAR STRUCTURE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; URACIL; URIDINE DIPHOSPHATE GLUCURONIC ACID;

EID: 77954922246     PISSN: 10849785     EISSN: None     Source Type: Journal    
DOI: 10.1089/cbr.2009.0727     Document Type: Article

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