-
1
-
-
9444282642
-
Active transport of imatinib into and out of cells: Implications for drug resistance
-
DOI 10.1182/blood-2003-12-4276
-
Thomas J, Wang L, Clark RE, Pirmohamed M. Active transport of imatinib into and out of cells: Implications for drug resistance. Blood 2004;104:3739-3745. (Pubitemid 39564452)
-
(2004)
Blood
, vol.104
, Issue.12
, pp. 3739-3745
-
-
Thomas, J.1
Wang, L.2
Clark, R.E.3
Pirmohamed, M.4
-
2
-
-
33745085275
-
OCT-1-mediated influx is a key determinant of the intracellular uptake of imatinib but not nilotinib (AMN107): Reduced OCT-1 activity is the cause of low in vitro sensitivity to imatinib
-
DOI 10.1182/blood-2005-11-4687
-
White DL, Saunders VA, Dang P, et al. OCT-1-mediated influx is a key determinant of the intracellular uptake of imatinib but not nilotinib (AMN107): Reduced OCT-1 activity is the cause of low in vitro sensitivity to imatinib. Blood 2006;108:697-704. (Pubitemid 44061372)
-
(2006)
Blood
, vol.108
, Issue.2
, pp. 697-704
-
-
White, D.L.1
Saunders, V.A.2
Dang, P.3
Engler, J.4
Zannettino, A.C.W.5
Cambareri, A.C.6
Quinn, S.R.7
Manley, P.W.8
Hughes, T.P.9
-
3
-
-
37049028176
-
Most CML patients who have a suboptimal response to imatinib have low OCT-1 activity: Higher doses of imatinib may overcome the negative impact of low OCT-1 activity
-
DOI 10.1182/blood-2007-06-093617
-
White DL, Saunders VA, Dang P, et al. Most CML patients who have a suboptimal response to imatinib have low OCT-1 activity: Higher doses of imatinib may overcome the negative impact of low OCT-1 activity. Blood 2007;110:4064-4072. (Pubitemid 350248463)
-
(2007)
Blood
, vol.110
, Issue.12
, pp. 4064-4072
-
-
White, D.L.1
Saunders, V.A.2
Dang, P.3
Engler, J.4
Venables, A.5
Zrim, S.6
Zannettino, A.7
Lynch, K.8
Manley, P.W.9
Hughes, T.10
-
5
-
-
38349193809
-
Expression of the uptake drug transporter hOCT1 is an important clinical determinant of the response to imatinib in chronic myeloid leukemia
-
Wang L, Giannoudis A, Lane S, et al. Expression of the uptake drug transporter hOCT1 is an important clinical determinant of the response to imatinib in chronic myeloid leukemia. Clin Pharmacol Ther 2008;83:258-264.
-
(2008)
Clin Pharmacol Ther
, vol.83
, pp. 258-264
-
-
Wang, L.1
Giannoudis, A.2
Lane, S.3
-
6
-
-
77955496432
-
BCR-ABL1 Oncogene Down-regulates the Expression of OCT1 in CML
-
Bazeos A, Marin D, Gerrard G, et al. BCR-ABL1 Oncogene Down-regulates the Expression of OCT1 in CML. ASH Annu Meet Abstr 2009;114:3248.
-
(2009)
ASH Annu Meet Abstr
, vol.114
, pp. 3248
-
-
Bazeos, A.1
Marin, D.2
Gerrard, G.3
-
7
-
-
77955485175
-
Reduced Activity of the OCT-1 Protein in Primitive CML Cells: A Likely Determinant of Stem Cell Resistance in Imatinib Treated CML Patients
-
Engler JR, Frede A, Zannettino ACW, et al. Reduced Activity of the OCT-1 Protein in Primitive CML Cells: A Likely Determinant of Stem Cell Resistance in Imatinib Treated CML Patients. ASH Annu Meet Abstr 2008;112:196.
-
(2008)
ASH Annu Meet Abstr
, vol.112
, pp. 196
-
-
Engler, J.R.1
Frede, A.2
Zannettino, A.C.W.3
-
8
-
-
34247555482
-
Chronic myeloid leukemia stem cells possess multiple unique features of resistance to BCR-ABL targeted therapies
-
DOI 10.1038/sj.leu.2404609, PII 2404609
-
Jiang X, Zhao Y, Smith C, et al. Chronic myeloid leukemia stem cells possess multiple unique features of resistance to BCR-ABL targeted therapies. Leukemia 2007;21:926-935. (Pubitemid 46672068)
-
(2007)
Leukemia
, vol.21
, Issue.5
, pp. 926-935
-
-
Jiang, X.1
Zhao, Y.2
Smith, C.3
Gasparetto, M.4
Turhan, A.5
Eaves, A.6
Eaves, C.7
-
9
-
-
77955492466
-
Pharmacogenomic Factors Such as the Expression of Imatinib Transporters (OCT-1, ABCB-1 and ABCG-2) at Diagnosis, OCT-1 SNPs, and Steady-State Imatinib and Desmethyl-Imatinib Trough Plasma Levels in de Novo Chronic Phase Chronic Myelogenous Leukemia, May Influence Disease Response to Imatinib
-
Labussiere H, Hayette S, Chabane K, et al. Pharmacogenomic Factors Such as the Expression of Imatinib Transporters (OCT-1, ABCB-1 and ABCG-2) at Diagnosis, OCT-1 SNPs, and Steady-State Imatinib and Desmethyl-Imatinib Trough Plasma Levels in De Novo Chronic Phase Chronic Myelogenous Leukemia, May Influence Disease Response to Imatinib. ASH Annu Meet Abstr 2008;112:2643.
-
(2008)
ASH Annu Meet Abstr
, vol.112
, pp. 2643
-
-
Labussiere, H.1
Hayette, S.2
Chabane, K.3
-
10
-
-
9144271651
-
Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time' quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR) - A Europe against cancer program
-
Beillard E, Pallisgaard N, van der Velden VH, Bi W, Dee R, van der Schoot E, Delabesse E, Macintyre E, Gottardi E, Saglio G, Watzinger F, Lion T, van Dongen JJ, Hokland P, Gabert J. Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time' quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR) - a Europe against cancer program. Leukemia 2003;17:2474-2486.
-
(2003)
Leukemia
, vol.17
, pp. 2474-2486
-
-
Beillard, E.1
Pallisgaard, N.2
Van Der Velden, V.H.3
Bi, W.4
Dee, R.5
Van Der Schoot, E.6
Delabesse, E.7
Macintyre, E.8
Gottardi, E.9
Saglio, G.10
Watzinger, F.11
Lion, T.12
Van Dongen, J.J.13
Hokland, P.14
Gabert, J.15
-
11
-
-
9144222001
-
Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - A Europe Against Cancer program
-
Gabert J, Beillard E, Van Der Velden VH, et al. Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - A Europe Against Cancer program. Leukemia 2003;17:2318-2357.
-
(2003)
Leukemia
, vol.17
, pp. 2318-2357
-
-
Gabert, J.1
Beillard, E.2
Van Der Velden, V.H.3
|