Strategies to minimize variability and bias associated with manual pipetting in ligand binding assays to assure data quality of protein therapeutic quantification

Journal of Pharmaceutical and Biomedical Analysis

Volumn 53, Issue 3, 2010, Pages 623-630

  Pandya, Kinnari ^a   Ray, Chad A ^b   Brunner, Laura ^a   Wang, Jin ^a   Lee, Jean W ^a   DeSilva, Binodh ^a  

^a AMGEN INC   (United States)

^b Radix BioSolutions   (United States)

Author keywords

Ligand binding assay; Pharmacokinetics; Pipetting; Sample dilution

Indexed keywords

ARTICLE; AUTOMATION; BINDING ASSAY; DILUTION; LIGAND BINDING; PERFORMANCE; PIPETTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; QUALITY CONTROL; RISK ASSESSMENT; ROBOTICS; VALIDATION PROCESS;

AUTOMATION; BIAS (EPIDEMIOLOGY); ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; LABORATORY TECHNIQUES AND PROCEDURES; LIGANDS; PROTEINS; QUALITY CONTROL;

EID: 77954887918     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2010.04.025     Document Type: Article

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