A review of photodynamic therapy (PDT) for the treatment of acne vulgaris

Journal of Drugs in Dermatology

Volumn 8, Issue 11, 2009, Pages 1010-1019

  Riddle, Christy C ^a   Terrell, Shaundre N ^b   Menser, Molly B ^a   Aires, Daniel J ^b,c   Schweiger, Eric S ^c  

^a Division of Dermatology   (United States)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOLEVULINIC ACID; AMINOLEVULINIC ACID METHYL ESTER; ANTIBIOTIC AGENT; HYDROQUINONE; PHOTOSENSITIZING AGENT; PLACEBO;

ACNE; ACNE VULGARIS; ARTICLE; BLUE LIGHT; CLINICAL EFFECTIVENESS; DRUG EFFICACY; ERYTHEMA; HUMAN; HYPERPIGMENTATION; INTENSE PULSED LIGHT; INTERMETHOD COMPARISON; MEDLINE; PHOTODYNAMIC THERAPY; PHOTOSENSITIVITY; PHOTOTHERAPY; PULSED DYE LASER; PUSTULE; RED LIGHT; SKIN EDEMA; SKIN MANIFESTATION; SKIN PAIN; SYSTEMATIC REVIEW; CLINICAL TRIAL (TOPIC); HOSPITALIZATION; LIGHT; METHODOLOGY; PATHOPHYSIOLOGY; PHOTOCHEMOTHERAPY; REVIEW; TIME; TREATMENT OUTCOME;

ACNE VULGARIS; CLINICAL TRIALS AS TOPIC; HUMANS; LIGHT; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TREATMENT OUTCOME;

EID: 77954881599     PISSN: 15459616     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Harper JC. An update on the pathogenesis and management of acne vulgaris. J Am Acad Dermatol. 2004;51(1 Suppl):S36-S38.
2. James WD. Clinical practice: Acne. N Engl J Med. 2005;352(14):1463-1472.
3. Mallon E, Newton JN, Klassen A, et al. The quality of life in acne: A comparison with general medical conditions using generic questionnaires. Br J Dermatol. 1999;140(4):672-676. (Pubitemid 29191387)
4. Management of acne: Summary, evidence report/technology assessment. No. 17. Rockville, Md.: Agency for Healthcare Research and Quality, March 2001. (AHRQ publication no. 01-E018.)
5. Babilas P, Karrer S, Sidoroff A, et al. Photodynamic therapy in dermatology- An update. Photodermatol Photoimmunol Photomed. 2005;21(3):142-149.
6. Hamzavi I, Lui H. Using light in dermatology: An update on lasers, ultraviolet phototherapy, and photodynamic therapy. Dermatol Clin. 2005;23:199-207.
7. Jeffes EW. Levulan: The first approved topical photosensitizer for the treatment of actinic keratosis. J Dermatolog Treat 2002;13 Suppl 1:S19-23.
8. Babilas P, Landthaler M, Szeimies RM. Photodynamic therapy in dermatology. Eur J Dermatol. 2006;16:240-248.
9. Varma S, Wilson H, Kurwa HA, et al. Bowen's disease, solar keratoses and superficial basal cell carcinoma treated by photodynamic therapy using a large-field incoherent light source. Br J Dermatol. 2001;144(3):567-574. (Pubitemid 32232013)
10. Clayton TH, Tait J, Whitehurst C, Yates VM. Photodynamic therapy for superficial basal cell carcinoma and Bowen's disease. Eur J Dermatol. 2006(1);16:39-41. (Pubitemid 43219403)
11. Kurwa HA, Barlow RJ. The role of photodynamic therapy in dermatology. Clin Exp Dermatol. 1999;24(3):143-148. (Pubitemid 29278958)
12. Dover JS, Bhatia AC, Stewart B, Arndt KA. Topical 5-aminolevulinic acid combined with intense pulsed light in the treatment of photoaging. Arch Dermatol. 2005;141(10):1247-1252.
13. Calzavara-Pinton PG, Venturini M, Sala R. Photodynamic therapy: Update 2006. Part 2: Clinical results. J Eur Acad Dermatol Venereol. 2007;21(4):439-451.
14. Ross EV. Optical treatments for acne. Dermatol Ther. 2005;18(3):253-266. (Pubitemid 41741779)
15. Pollock P, Turner D, Stringer MR, et al. Topical aminolaevulinic acid-photodynamic therapy for the treatment of acne vulgaris: A study of clinical efficacy and mechanism of action. Br J Dermatol. 2004;151(3):616-622. (Pubitemid 39330886)
16. Nouri K, Ballard CS. Laser therapy for acne. Clin Dermatol. 2006;24(1):26-32. (Pubitemid 43112352)
17. Ashkenazi H, Malik Z, Harth Y. Eradication of Propionibacterium acnes by its endogenic porphyrins after illumination with high intensity blue light. FEMS Immunol Med Microbiol. 2003;35(1):17-24. (Pubitemid 36173500)
18. Kennedy JC, Pottier RH, Pross DC. Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience. J Photochem Photobiol B. 1990;6(1-2):143-148.
19. Hongcharu W, Taylor CR, Chang Y, et al. Topical ALA-photodynamic therapy for the treatment of acne vulgaris. J Invest Dermatol. 2000;115(2):183-192.
20. Hruza GJ, Geronemus RG, Dover JS, Arndt. Lasers in dermatology- 1993. Arch Dermatol. 1993;129(8):1026-1035.
21. Bhardwaj SS, Rohrer TE, Arndt K, et al. Lasers and light therapy for acne vulgaris. Semin Cutan Med Surg. 2005;24(2):107-112. (Pubitemid 41111818)
22. Ortiz A, Van Vliet M, Lask GP, Yamauchi PS. A review of lasers and light sources in the treatment of acne vulgaris. J Cosmet Laser Ther. 2005;7(2):69-75. (Pubitemid 41512726)
23. Young S, Bolton P, Dyson M, et al. Macrophage responsiveness to light therapy. Lasers Surg Med. 1989;9(5):497-505. (Pubitemid 19247727)
24. Rivard J, Ozog D. Case reports: Henry Ford Hospital Dermatology experience with Levulan Kerastick and blue light photodynamic therapy. J Drugs Dermatol. 2006;5(6):556-561.
25. Taub AF. Photodynamic therapy for the treatment of acne: A pilot study. J Drugs Dermatol. 2004;3(6 Suppl):S10-S14.
26. Goldman MP, Boyce SM. A single-center study of aminolevulinic acid and 417 nm photodynamic therapy in the treatment of moderate to severe acne. J Drugs Dermatol. 2003; 2(4):393-396.
27. Akaraphanth R, Kanjanawanitchkul W, Gritiyarangsan P. Efficacy of ALA-PDT versus blue light in the treatment of acne. Photodermatol Photoimmunol Photomed. 2007;23(5):186-190.
28. Taub AF. A comparison of intense pulsed light, combination radiofrequency and intense pulsed light, and blue light in photodynamic therapy for acne vulgaris. J Drugs Dermatol. 2007;6(10):1010-1016.
29. Rojanamatin J, Choawawanich P. Treatment of inflammatory facial acne vulgaris with intense pulsed light and short contact of topical 5-aminolevulinic acid: A pilot study. Dermatol Surg. 2006;32(8):991-997.
30. Santos MA, Belo VG, Santos G. Effectiveness of photodynamic therapy with topical 5-aminolevulinic acid and intense pulsed light versus intense pulsed light alone in the treatment of acne vulgaris: Comparative study. Dermatol Surg. 2005;31(8 Pt 1):910-915. (Pubitemid 44795685)
31. Gold MH, Bradshaw VL, Boring MM, et al. The use of a novel intense pulsed light and heat source and ALA-PDT in the treatment of moderate to severe inflammatory acne vulgaris. J Drugs Dermatol. 2004;3(6 Suppl):S15-S19.
32. Gold MH, Biron JA, Boring M, et al. Treatment of moderate to severe inflammatory acne vulgaris: Photodynamic therapy with 5-aminolevulinic acid and a novel advanced fluorescence technology pulsed light source. J Drugs Dermatol. 2007;6(3):319-322.
33. Yeung CK, Shek SY, Bjerring P, et al. A comparative study of intense pulsed light alone and its combination with photodynamic therapy for the treatment of facial acne in Asian skin. Lasers Surg Med. 2007;39(1):1-6. (Pubitemid 46239792)
34. Haedersdal M, Togsverd-Bo K, Wiegell SR, Wulf HC. Long-pulsed dye laser versus long-pulsed dye laser-assisted photodynamic therapy for acne vulgaris: A randomized controlled trial. J Am Acad Dermatol. 2008;58(3):387-394. (Pubitemid 351227447)
35. Alexiades-Armenakas M. Long-pulsed dye laser-mediated photodynamic therapy combined with topical therapy for mild to severe comedonal, inflammatory, or cystic acne. J Drugs Dermatol. 2006;5(1):45-55.
36. Horfelt C, Funk J, Frohm-Nilsson M, et al. Topical methyl aminolaevulinate photodynamic therapy for treatment of facial acne vulgaris: Results of a randomized, controlled study. Br J Dermatol. 2006;155(3):608-613. (Pubitemid 44215494)
37. Wiegell SR, Wulf HC. Photodynamic therapy of acne vulgaris using methyl aminolaevulinate: A blinded, randomized, controlled trial. Br J Dermatol. 2006;154(4):969-976.
38. Wiegell SR, Wulf HC. Photodynamic therapy of acne vulgaris using 5-aminolevulinic acid versus methyl aminolevulinate. J Am Acad Dermatol. 2006;54(4):647-651.
39. Hong SB, Lee MH. Topical aminolevulinic acid-photodynamic therapy for the treatment of acne vulgaris. Photodermatol Photoimmunol Photomed. 2005;21(6):322-325.
40. Hörfelt C, Stenquist B, Larkö O, et al. Photodynamic therapy for acne vulgaris: A pilot study of the dose-response and mechanism of action. Acta Derm Venereol. 2007;87(4):325-329.
41. Mavilia L, Malara G, Moretti G, et al. Photodynamic therapy of acne using methyl aminolaevulinate diluted to 4% together with low doses of red light. Br J Dermatol. 2007;157(4):810-811. (Pubitemid 47389872)
42. Itoh Y, Ninomiya Y, Tajima S, Ishibashi. Photodynamic therapy for acne vulgaris with topical 5-aminolevulinic acid. Arch Dermatol. 2000;136(9):1093- 1095.
43. Gold MH, Goldman MP. 5-Aminolevulinic acid photodynamic therapy: Where we have been and where we are going. Dermatol Surg. 2004;30(8):1077-1084.
44. Peng Q, Soler AM, Warloe T, et al. Selective distribution of porphyrins in skin-thick BCC after topical application of methyl 5-aminolevulinate. J Photochem Photobiol. 2001;62(3):140-145. (Pubitemid 32898834)
45. Gold MH. 5-Aminolevulinic acid photodynamic therapy versus methyl aminolevulinate photodynamic therapy for inflammatory acne vulgaris. J Am Acad Dermatol. 2006;58(2 Suppl):S60-S61.
46. DUSA Pharmaceuticals, Inc.: American Academy of Dermatology Highlights ALA Photodynamic Therapy in Media Presentation and Press Release During 2006 Annual Meeting.