메뉴 건너뛰기




Volumn 53, Issue 3, 2010, Pages 583-590

Stereoselective determination of venlafaxine and its three demethylated metabolites in human plasma and whole blood by liquid chromatography with electrospray tandem mass spectrometric detection and solid phase extraction

Author keywords

Enantiomers; Human; LC ESI MS MS; Metabolites; Venlafaxine

Indexed keywords

DESVENLAFAXINE; DRUG METABOLITE; MEXILETINE; N DESMETHYLVENLAFAXINE; N,O DIDESMETHYLVENLAFAXINE; UNCLASSIFIED DRUG; VENLAFAXINE;

EID: 77954861741     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2010.03.043     Document Type: Article
Times cited : (56)

References (32)
  • 1
    • 34547689154 scopus 로고    scopus 로고
    • Chirality and pharmacokinetics: an area of neglected dimensionality?
    • Hutt A.J. Chirality and pharmacokinetics: an area of neglected dimensionality?. Drug Metabol. Drug Interact. 2007, 22:79-112.
    • (2007) Drug Metabol. Drug Interact. , vol.22 , pp. 79-112
    • Hutt, A.J.1
  • 2
    • 34547193773 scopus 로고    scopus 로고
    • Stereoselectivity in drug metabolism
    • Lu H. Stereoselectivity in drug metabolism. Expert Opin. Drug Metab. Toxicol. 2007, 3:149-158.
    • (2007) Expert Opin. Drug Metab. Toxicol. , vol.3 , pp. 149-158
    • Lu, H.1
  • 3
    • 33751574640 scopus 로고    scopus 로고
    • Drug disposition in three dimensions: an update on stereoselectivity in pharmacokinetics
    • Brocks D.R. Drug disposition in three dimensions: an update on stereoselectivity in pharmacokinetics. Biopharm. Drug Dispos. 2006, 27:387-406.
    • (2006) Biopharm. Drug Dispos. , vol.27 , pp. 387-406
    • Brocks, D.R.1
  • 4
    • 0022879288 scopus 로고
    • Antidepressant biochemical profile of the novel bicyclic compound Wy-45,030, an ethyl cyclohexanol derivative
    • Muth E.A., Haskins J.T., Moyer J.A., Husbands G.E., Nielsen S.T., Sigg E.B. Antidepressant biochemical profile of the novel bicyclic compound Wy-45,030, an ethyl cyclohexanol derivative. Biochem. Pharmacol. 1986, 35:4493-4497.
    • (1986) Biochem. Pharmacol. , vol.35 , pp. 4493-4497
    • Muth, E.A.1    Haskins, J.T.2    Moyer, J.A.3    Husbands, G.E.4    Nielsen, S.T.5    Sigg, E.B.6
  • 5
    • 0028801952 scopus 로고
    • A review of its pharmacology and therapeutic potential in depression
    • Holliday S.M., Benfield P., Venlafaxine A review of its pharmacology and therapeutic potential in depression. Drugs 1995, 49(2):280-294.
    • (1995) Drugs , vol.49 , Issue.2 , pp. 280-294
    • Holliday, S.M.1    Benfield, P.2    Venlafaxine3
  • 7
    • 0033136981 scopus 로고    scopus 로고
    • O- and N-demethylation of venlafaxine in vitro by human liver microsomes and by microsomes from cDNA-transfected cells: effect of metabolic inhibitors and SSRI antidepressants
    • Fogelman S.M., Schmider J., Venkatakrishnan K., von Moltke L.L., Harmatz J.S., Shader R.I., Greenblatt D.J. O- and N-demethylation of venlafaxine in vitro by human liver microsomes and by microsomes from cDNA-transfected cells: effect of metabolic inhibitors and SSRI antidepressants. Neuropsychopharmacology 1999, 20:480-490.
    • (1999) Neuropsychopharmacology , vol.20 , pp. 480-490
    • Fogelman, S.M.1    Schmider, J.2    Venkatakrishnan, K.3    von Moltke, L.L.4    Harmatz, J.S.5    Shader, R.I.6    Greenblatt, D.J.7
  • 9
    • 0035812480 scopus 로고    scopus 로고
    • Rapid high-performance liquid chromatographic measurement of venlafaxine and O-desmethylvenlafaxine in human plasma Application to management of acute intoxications
    • Matoga M., Pehourcq F., Titier K., Dumora F., Jarry C. Rapid high-performance liquid chromatographic measurement of venlafaxine and O-desmethylvenlafaxine in human plasma Application to management of acute intoxications. J. Chromatogr. B Biomed. Sci. Appl. 2001, 760:213-218.
    • (2001) J. Chromatogr. B Biomed. Sci. Appl. , vol.760 , pp. 213-218
    • Matoga, M.1    Pehourcq, F.2    Titier, K.3    Dumora, F.4    Jarry, C.5
  • 10
    • 0037097704 scopus 로고    scopus 로고
    • Stability indicating LC method for the estimation of venlafaxine in pharmaceutical formulations
    • Makhija S.N., Vavia P.R. Stability indicating LC method for the estimation of venlafaxine in pharmaceutical formulations. J. Pharm. Biomed. Anal. 2002, 28:1055-1059.
    • (2002) J. Pharm. Biomed. Anal. , vol.28 , pp. 1055-1059
    • Makhija, S.N.1    Vavia, P.R.2
  • 11
    • 34548174700 scopus 로고    scopus 로고
    • Analysis of the second generation antidepressant venlafaxine and its main active metabolite O-desmethylvenlafaxine in human plasma by HPLC with spectrofluorimetric detection
    • Mandrioli R., Mercolini L., Cesta R., Fanali S., Amore M., Raggi M.A. Analysis of the second generation antidepressant venlafaxine and its main active metabolite O-desmethylvenlafaxine in human plasma by HPLC with spectrofluorimetric detection. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2007, 856:88-94.
    • (2007) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. , vol.856 , pp. 88-94
    • Mandrioli, R.1    Mercolini, L.2    Cesta, R.3    Fanali, S.4    Amore, M.5    Raggi, M.A.6
  • 12
    • 0027952870 scopus 로고
    • A high-performance liquid chromatographic method for the simultaneous determination of venlafaxine and O-desmethylvenlafaxine in biological fluids
    • Hicks D.R., Wolaniuk D., Russell A., Cavanaugh N., Kraml M. A high-performance liquid chromatographic method for the simultaneous determination of venlafaxine and O-desmethylvenlafaxine in biological fluids. Ther. Drug Monit. 1994, 16:100-107.
    • (1994) Ther. Drug Monit. , vol.16 , pp. 100-107
    • Hicks, D.R.1    Wolaniuk, D.2    Russell, A.3    Cavanaugh, N.4    Kraml, M.5
  • 13
    • 0026681563 scopus 로고
    • The disposition of venlafaxine enantiomers in dogs, rats, and humans receiving venlafaxine
    • Wang C.P., Howell S.R., Scatina J., Sisenwine S.F. The disposition of venlafaxine enantiomers in dogs, rats, and humans receiving venlafaxine. Chirality 1992, 4:84-90.
    • (1992) Chirality , vol.4 , pp. 84-90
    • Wang, C.P.1    Howell, S.R.2    Scatina, J.3    Sisenwine, S.F.4
  • 14
    • 0031435447 scopus 로고    scopus 로고
    • Rapid determination of venlafaxine and O-desmethylvenlafaxine in human plasma by high-performance liquid chromatography with fluorimetric detection
    • Vu R.L., Helmeste D., Albers L., Reist C. Rapid determination of venlafaxine and O-desmethylvenlafaxine in human plasma by high-performance liquid chromatography with fluorimetric detection. J. Chromatogr. B Biomed. Sci. Appl. 1997, 703:195-201.
    • (1997) J. Chromatogr. B Biomed. Sci. Appl. , vol.703 , pp. 195-201
    • Vu, R.L.1    Helmeste, D.2    Albers, L.3    Reist, C.4
  • 15
    • 10344260813 scopus 로고    scopus 로고
    • Quantification of venlafaxine and O-desmethylvenlafaxine in human serum using HPLC analysis
    • Waschgler R., Moll W., Konig P., Conca A. Quantification of venlafaxine and O-desmethylvenlafaxine in human serum using HPLC analysis. Int. J. Clin. Pharmacol. Ther. 2004, 42:724-728.
    • (2004) Int. J. Clin. Pharmacol. Ther. , vol.42 , pp. 724-728
    • Waschgler, R.1    Moll, W.2    Konig, P.3    Conca, A.4
  • 16
    • 49849098026 scopus 로고    scopus 로고
    • Determination of venlafaxine in human plasma by high-performance liquid chromatography using cloud-point extraction and spectrofluorimetric detection
    • Qin X.Y., Meng J., Li X.Y., Zhou J., Sun X.L., Wen A.D. Determination of venlafaxine in human plasma by high-performance liquid chromatography using cloud-point extraction and spectrofluorimetric detection. J. Chromatogr. B Analyt Technol. Biomed. Life Sci. 2008, 872:38-42.
    • (2008) J. Chromatogr. B Analyt Technol. Biomed. Life Sci. , vol.872 , pp. 38-42
    • Qin, X.Y.1    Meng, J.2    Li, X.Y.3    Zhou, J.4    Sun, X.L.5    Wen, A.D.6
  • 17
    • 33947596319 scopus 로고    scopus 로고
    • Liquid chromatography-mass spectrometry method for the determination of venlafaxine in human plasma and application to a pharmacokinetic study
    • Wei Z., Bing-Ren X., Cai-Yun W. Liquid chromatography-mass spectrometry method for the determination of venlafaxine in human plasma and application to a pharmacokinetic study. Biomed. Chromatogr. 2007, 21:266-272.
    • (2007) Biomed. Chromatogr. , vol.21 , pp. 266-272
    • Wei, Z.1    Bing-Ren, X.2    Cai-Yun, W.3
  • 18
    • 34247180722 scopus 로고    scopus 로고
    • Simultaneous stereoselective analysis of venlafaxine and O-desmethylvenlafaxine enantiomers in human plasma by HPLC-ESI/MS using a vancomycin chiral column
    • Liu W., Wang F., Li H.D. Simultaneous stereoselective analysis of venlafaxine and O-desmethylvenlafaxine enantiomers in human plasma by HPLC-ESI/MS using a vancomycin chiral column. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2007, 850:183-189.
    • (2007) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. , vol.850 , pp. 183-189
    • Liu, W.1    Wang, F.2    Li, H.D.3
  • 19
    • 0034256985 scopus 로고    scopus 로고
    • Simultaneous stereoselective analysis of venlafaxine and O-desmethylvenlafaxine enantiomers in clinical samples by capillary electrophoresis using charged cyclodextrins
    • Rudaz S., Stella C., Balant-Gorgia A.E., Fanali S., Veuthey J.L. Simultaneous stereoselective analysis of venlafaxine and O-desmethylvenlafaxine enantiomers in clinical samples by capillary electrophoresis using charged cyclodextrins. J. Pharm. Biomed. Anal. 2000, 23:107-115.
    • (2000) J. Pharm. Biomed. Anal. , vol.23 , pp. 107-115
    • Rudaz, S.1    Stella, C.2    Balant-Gorgia, A.E.3    Fanali, S.4    Veuthey, J.L.5
  • 20
    • 0035369730 scopus 로고    scopus 로고
    • Use of vancomycin silica stationary phase in packed capillary electrochromatography II. Enantiomer separation of venlafaxine and O-desmethylvenlafaxine in human plasma
    • Fanali S., Rudaz S., Veuthey J.L., Desiderio C. Use of vancomycin silica stationary phase in packed capillary electrochromatography II. Enantiomer separation of venlafaxine and O-desmethylvenlafaxine in human plasma. J. Chromatogr. A 2001, 919:195-203.
    • (2001) J. Chromatogr. A , vol.919 , pp. 195-203
    • Fanali, S.1    Rudaz, S.2    Veuthey, J.L.3    Desiderio, C.4
  • 21
    • 0027932370 scopus 로고
    • Evaluation of the macrocyclic antibiotic vancomycin as a chiral selector for capillary electrophoresis
    • Armstrong D.W., Rundlett K.L., Chen J.R. Evaluation of the macrocyclic antibiotic vancomycin as a chiral selector for capillary electrophoresis. Chirality 1994, 6:496-509.
    • (1994) Chirality , vol.6 , pp. 496-509
    • Armstrong, D.W.1    Rundlett, K.L.2    Chen, J.R.3
  • 22
    • 0041846678 scopus 로고    scopus 로고
    • Analysis of eighteen antidepressants, four atypical antipsychotics and active metabolites in serum by liquid chromatography: a simple tool for therapeutic drug monitoring
    • Frahnert C., Rao M.L., Grasmader K. Analysis of eighteen antidepressants, four atypical antipsychotics and active metabolites in serum by liquid chromatography: a simple tool for therapeutic drug monitoring. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2003, 794:35-47.
    • (2003) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. , vol.794 , pp. 35-47
    • Frahnert, C.1    Rao, M.L.2    Grasmader, K.3
  • 23
    • 28844450389 scopus 로고    scopus 로고
    • Liquid chromatography-tandem mass spectrometry (LC-MS-MS) method for simultaneous determination of venlafaxine and its active metabolite O-desmethyl venlafaxine in human plasma
    • Bhatt J., Jangid A., Venkatesh G., Subbaiah G., Singh S. Liquid chromatography-tandem mass spectrometry (LC-MS-MS) method for simultaneous determination of venlafaxine and its active metabolite O-desmethyl venlafaxine in human plasma. J. Chromatogr. B Analyt Technol. Biomed. Life Sci. 2005, 829:75-81.
    • (2005) J. Chromatogr. B Analyt Technol. Biomed. Life Sci. , vol.829 , pp. 75-81
    • Bhatt, J.1    Jangid, A.2    Venkatesh, G.3    Subbaiah, G.4    Singh, S.5
  • 24
    • 27944440037 scopus 로고    scopus 로고
    • Development of a solid phase extraction for 13 'new' generation antidepressants and their active metabolites for gas chromatographic-mass spectrometric analysis
    • Wille S.M., Maudens K.E., Van Peteghem C.H., Lambert W.E. Development of a solid phase extraction for 13 'new' generation antidepressants and their active metabolites for gas chromatographic-mass spectrometric analysis. J. Chromatogr. A 2005, 1098:19-29.
    • (2005) J. Chromatogr. A , vol.1098 , pp. 19-29
    • Wille, S.M.1    Maudens, K.E.2    Van Peteghem, C.H.3    Lambert, W.E.4
  • 25
    • 34249681376 scopus 로고    scopus 로고
    • Employing atmospheric pressure photoionization in liquid chromatography/tandem mass spectrometry to minimize ion suppression and matrix effects for the quantification of venlafaxine and O-desmethylvenlafaxine
    • Theron H.B., van der Merwe M.J., Swart K.J., van der Westhuizen J.H. Employing atmospheric pressure photoionization in liquid chromatography/tandem mass spectrometry to minimize ion suppression and matrix effects for the quantification of venlafaxine and O-desmethylvenlafaxine. Rapid Commun. Mass Spectrom. 2007, 21:1680-1686.
    • (2007) Rapid Commun. Mass Spectrom. , vol.21 , pp. 1680-1686
    • Theron, H.B.1    van der Merwe, M.J.2    Swart, K.J.3    van der Westhuizen, J.H.4
  • 26
    • 0037663202 scopus 로고    scopus 로고
    • Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS
    • Matuszewski B.K., Constanzer M.L., Chavez-Eng C.M. Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS. Anal. Chem. 2003, 75:3019-3030.
    • (2003) Anal. Chem. , vol.75 , pp. 3019-3030
    • Matuszewski, B.K.1    Constanzer, M.L.2    Chavez-Eng, C.M.3
  • 27
    • 1842480646 scopus 로고    scopus 로고
    • Transforming chiral liquid chromatography methodologies into more sensitive liquid chromatography-electrospray ionization mass spectrometry without losing enantioselectivity
    • Desai M.J., Armstrong D.W. Transforming chiral liquid chromatography methodologies into more sensitive liquid chromatography-electrospray ionization mass spectrometry without losing enantioselectivity. J. Chromatogr. A 2004, 1035:203-210.
    • (2004) J. Chromatogr. A , vol.1035 , pp. 203-210
    • Desai, M.J.1    Armstrong, D.W.2
  • 28
    • 0029618809 scopus 로고
    • Accuracy in the chromatographic determination of extreme enantiomeric ratios: A critical reflection
    • Meyer V. Accuracy in the chromatographic determination of extreme enantiomeric ratios: A critical reflection. Chirality 1995, 7:567-571.
    • (1995) Chirality , vol.7 , pp. 567-571
    • Meyer, V.1
  • 30
    • 1542742414 scopus 로고    scopus 로고
    • Enantioselective analysis of citalopram and its metabolites in postmortem blood and genotyping for CYD2D6 and CYP2C19
    • Holmgren P., Carlsson B., Zackrisson A.L., Lindblom B., Dahl M.L., Scordo M.G., et al. Enantioselective analysis of citalopram and its metabolites in postmortem blood and genotyping for CYD2D6 and CYP2C19. J. Anal. Toxicol. 2004, 28:94-104.
    • (2004) J. Anal. Toxicol. , vol.28 , pp. 94-104
    • Holmgren, P.1    Carlsson, B.2    Zackrisson, A.L.3    Lindblom, B.4    Dahl, M.L.5    Scordo, M.G.6
  • 32
    • 34250364501 scopus 로고    scopus 로고
    • Reference concentrations of antidepressants: a compilation of postmortem and therapeutic levels
    • Reis M., Aamo T., Ahlner J., Druid H. Reference concentrations of antidepressants: a compilation of postmortem and therapeutic levels. J. Anal. Toxicol. 2007, 31:254-264.
    • (2007) J. Anal. Toxicol. , vol.31 , pp. 254-264
    • Reis, M.1    Aamo, T.2    Ahlner, J.3    Druid, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.