메뉴 건너뛰기




Volumn 77, Issue 3, 2010, Pages 605-617

M. tuberculosis intramembrane protease Rip1 controls transcription through three anti-sigma factor substrates

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIOFERRITIN; KATG PROTEIN; MYCOLIC ACID; PHENANTHROLINE; PROTEASE RIP1; PROTEINASE; SIGMA FACTOR; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; MEMBRANE PROTEIN; METALLOPROTEINASE;

EID: 77954859332     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2010.07232.x     Document Type: Article
Times cited : (53)

References (43)
  • 1
    • 56949096401 scopus 로고    scopus 로고
    • Regulation by destruction: Design of the sigmaE envelope stress response
    • Ades, S.E. (2008) Regulation by destruction: design of the sigmaE envelope stress response. Curr Opin Microbiol 11 : 535 540.
    • (2008) Curr Opin Microbiol , vol.11 , pp. 535-540
    • Ades, S.E.1
  • 2
    • 33845991188 scopus 로고    scopus 로고
    • Characterization of the Mycobacterium tuberculosis sigma factor SigM: Virulence assessment and identification of SigM-dependent genes
    • Agarwal, N., Woolwine, S.C., Tyagi, S. Bishai, W.R. (2006) Characterization of the Mycobacterium tuberculosis sigma factor SigM: virulence assessment and identification of SigM-dependent genes. Infect Immun 75 : 452 461.
    • (2006) Infect Immun , vol.75 , pp. 452-461
    • Agarwal, N.1    Woolwine, S.C.2    Tyagi, S.3    Bishai, W.R.4
  • 3
    • 0037102509 scopus 로고    scopus 로고
    • DegS and YaeL participate sequentially in the cleavage of RseA to activate the sigma(E)-dependent extracytoplasmic stress response
    • Alba, B.M., Leeds, J.A., Onufryk, C., Lu, C.Z. Gross, C.A. (2002) DegS and YaeL participate sequentially in the cleavage of RseA to activate the sigma(E)-dependent extracytoplasmic stress response. Genes Dev 16 : 2156 2168.
    • (2002) Genes Dev , vol.16 , pp. 2156-2168
    • Alba, B.M.1    Leeds, J.A.2    Onufryk, C.3    Lu, C.Z.4    Gross, C.A.5
  • 4
    • 67349100157 scopus 로고    scopus 로고
    • Ferritins: A family of molecules for iron storage, antioxidation and more
    • Arosio, P., Ingrassia, R. Cavadini, P. (2009) Ferritins: a family of molecules for iron storage, antioxidation and more. Biochim Biophys Acta 1790 : 589 599.
    • (2009) Biochim Biophys Acta , vol.1790 , pp. 589-599
    • Arosio, P.1    Ingrassia, R.2    Cavadini, P.3
  • 5
    • 0030931885 scopus 로고    scopus 로고
    • Conditionally replicating mycobacteriophages: A system for transposon delivery to Mycobacterium tuberculosis
    • Bardarov, S., Kriakov, J., Carriere, C., Yu, S., Vaamonde, C., McAdam, R.A., et al. (1997) Conditionally replicating mycobacteriophages: a system for transposon delivery to Mycobacterium tuberculosis. Proc Natl Acad Sci USA 94 : 10961 10966.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10961-10966
    • Bardarov, S.1    Kriakov, J.2    Carriere, C.3    Yu, S.4    Vaamonde, C.5    McAdam, R.A.6
  • 6
    • 65749086909 scopus 로고    scopus 로고
    • Mycolic acid cyclopropanation is essential for viability, drug resistance, and cell wall integrity of Mycobacterium tuberculosis
    • Barkan, D., Liu, Z., Sacchettini, J.C. Glickman, M.S. (2009) Mycolic acid cyclopropanation is essential for viability, drug resistance, and cell wall integrity of Mycobacterium tuberculosis. Chem Biol 16 : 499 509.
    • (2009) Chem Biol , vol.16 , pp. 499-509
    • Barkan, D.1    Liu, Z.2    Sacchettini, J.C.3    Glickman, M.S.4
  • 7
    • 33749183115 scopus 로고    scopus 로고
    • Regulated intramembrane proteolysis of FtsL protein and the control of cell division in Bacillus subtilis
    • Bramkamp, M., Weston, L., Daniel, R.A. Errington, J. (2006) Regulated intramembrane proteolysis of FtsL protein and the control of cell division in Bacillus subtilis. Mol Microbiol 62 : 580 591.
    • (2006) Mol Microbiol , vol.62 , pp. 580-591
    • Bramkamp, M.1    Weston, L.2    Daniel, R.A.3    Errington, J.4
  • 8
    • 34548252292 scopus 로고    scopus 로고
    • A conserved structural module regulates transcriptional responses to diverse stress signals in bacteria
    • Campbell, E.A., Greenwell, R., Anthony, J.R., Wang, S., Lim, L., Das, K., et al. (2007) A conserved structural module regulates transcriptional responses to diverse stress signals in bacteria. Mol Cell 27 : 793 805.
    • (2007) Mol Cell , vol.27 , pp. 793-805
    • Campbell, E.A.1    Greenwell, R.2    Anthony, J.R.3    Wang, S.4    Lim, L.5    Das, K.6
  • 9
    • 0021281752 scopus 로고
    • A controlled trial of 2-month, 3-month, and 12-month regimens of chemotherapy for sputum-smear-negative pulmonary tuberculosis. Results at 60 months
    • Council, B.M.R. (1984) A controlled trial of 2-month, 3-month, and 12-month regimens of chemotherapy for sputum-smear-negative pulmonary tuberculosis. Results at 60 months. Am Rev Respir Dis 130 : 23 28.
    • (1984) Am Rev Respir Dis , vol.130 , pp. 23-28
    • Council, B.M.R.1
  • 10
    • 33645532080 scopus 로고    scopus 로고
    • Posttranslational regulation of Mycobacterium tuberculosis extracytoplasmic-function sigma factor sigma L and roles in virulence and in global regulation of gene expression
    • Dainese, E., Rodrigue, S., Delogu, G., Provvedi, R., Laflamme, L., Brzezinski, R., et al. (2006) Posttranslational regulation of Mycobacterium tuberculosis extracytoplasmic-function sigma factor sigma L and roles in virulence and in global regulation of gene expression. Infect Immun 74 : 2457 2461.
    • (2006) Infect Immun , vol.74 , pp. 2457-2461
    • Dainese, E.1    Rodrigue, S.2    Delogu, G.3    Provvedi, R.4    Laflamme, L.5    Brzezinski, R.6
  • 11
    • 0033973479 scopus 로고    scopus 로고
    • The salicylate-derived mycobactin siderophores of Mycobacterium tuberculosis are essential for growth in macrophages
    • De Voss, J.J., Rutter, K., Schroeder, B.G., Su, H., Zhu, Y. Barry, C.E., 3rd. (2000) The salicylate-derived mycobactin siderophores of Mycobacterium tuberculosis are essential for growth in macrophages. Proc Natl Acad Sci USA 97 : 1252 1257.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1252-1257
    • De Voss, J.J.1    Rutter, K.2    Schroeder, B.G.3    Su, H.4    Zhu, Y.5    Barry III, C.E.6
  • 12
    • 33644991496 scopus 로고    scopus 로고
    • Global epidemiology of tuberculosis
    • Dye, C. (2006) Global epidemiology of tuberculosis. Lancet 367 : 938 940.
    • (2006) Lancet , vol.367 , pp. 938-940
    • Dye, C.1
  • 14
    • 33746088411 scopus 로고    scopus 로고
    • Evidence for a novel protease governing regulated intramembrane proteolysis and resistance to antimicrobial peptides in Bacillus subtilis
    • Ellermeier, C.D. Losick, R. (2006) Evidence for a novel protease governing regulated intramembrane proteolysis and resistance to antimicrobial peptides in Bacillus subtilis. Genes Dev 20 : 1911 1922.
    • (2006) Genes Dev , vol.20 , pp. 1911-1922
    • Ellermeier, C.D.1    Losick, R.2
  • 15
    • 0035169902 scopus 로고    scopus 로고
    • The Mycobacterium tuberculosis IdeR is a dual functional regulator that controls transcription of genes involved in iron acquisition, iron storage and survival in macrophages
    • Gold, B., Rodriguez, G.M., Marras, S.A., Pentecost, M. Smith, I. (2001) The Mycobacterium tuberculosis IdeR is a dual functional regulator that controls transcription of genes involved in iron acquisition, iron storage and survival in macrophages. Mol Microbiol 42 : 851 865.
    • (2001) Mol Microbiol , vol.42 , pp. 851-865
    • Gold, B.1    Rodriguez, G.M.2    Marras, S.A.3    Pentecost, M.4    Smith, I.5
  • 16
    • 26444518218 scopus 로고    scopus 로고
    • The Mycobacterium tuberculosis extracytoplasmic-function sigma factor SigL regulates polyketide synthases and secreted or membrane proteins and is required for virulence
    • Hahn, M.Y., Raman, S., Anaya, M. Husson, R.N. (2005) The Mycobacterium tuberculosis extracytoplasmic-function sigma factor SigL regulates polyketide synthases and secreted or membrane proteins and is required for virulence. J Bacteriol 187 : 7062 7071.
    • (2005) J Bacteriol , vol.187 , pp. 7062-7071
    • Hahn, M.Y.1    Raman, S.2    Anaya, M.3    Husson, R.N.4
  • 17
    • 33749179201 scopus 로고    scopus 로고
    • YpdC determines site-1 degradation in regulated intramembrane proteolysis of the RsiW anti-sigma factor of Bacillus subtilis
    • Heinrich, J. Wiegert, T. (2006) YpdC determines site-1 degradation in regulated intramembrane proteolysis of the RsiW anti-sigma factor of Bacillus subtilis. Mol Microbiol 62 : 566 579.
    • (2006) Mol Microbiol , vol.62 , pp. 566-579
    • Heinrich, J.1    Wiegert, T.2
  • 18
    • 72049093490 scopus 로고    scopus 로고
    • Two proteolytic modules are involved in regulated intramembrane proteolysis of Bacillus subtilis RsiW
    • Heinrich, J., Hein, K. Wiegert, T. (2009) Two proteolytic modules are involved in regulated intramembrane proteolysis of Bacillus subtilis RsiW. Mol Microbiol 74 : 1412 1426.
    • (2009) Mol Microbiol , vol.74 , pp. 1412-1426
    • Heinrich, J.1    Hein, K.2    Wiegert, T.3
  • 19
    • 0037102458 scopus 로고    scopus 로고
    • YaeL (EcfE) activates the sigma(E) pathway of stress response through a site-2 cleavage of anti-sigma(E), RseA
    • Kanehara, K., Ito, K. Akiyama, Y. (2002) YaeL (EcfE) activates the sigma(E) pathway of stress response through a site-2 cleavage of anti-sigma(E), RseA. Genes Dev 16 : 2147 2155.
    • (2002) Genes Dev , vol.16 , pp. 2147-2155
    • Kanehara, K.1    Ito, K.2    Akiyama, Y.3
  • 20
    • 33745288760 scopus 로고    scopus 로고
    • Examination of Mycobacterium tuberculosis sigma factor mutants using low-dose aerosol infection of guinea pigs suggests a role for SigC in pathogenesis
    • Karls, R.K., Guarner, J., McMurray, D.N., Birkness, K.A. Quinn, F.D. (2006) Examination of Mycobacterium tuberculosis sigma factor mutants using low-dose aerosol infection of guinea pigs suggests a role for SigC in pathogenesis. Microbiology 152 : 1591 1600.
    • (2006) Microbiology , vol.152 , pp. 1591-1600
    • Karls, R.K.1    Guarner, J.2    McMurray, D.N.3    Birkness, K.A.4    Quinn, F.D.5
  • 21
    • 29344444795 scopus 로고    scopus 로고
    • Site-2 protease regulated intramembrane proteolysis: Sequence homologs suggest an ancient signaling cascade
    • Kinch, L.N., Ginalski, K. Grishin, N.V. (2006) Site-2 protease regulated intramembrane proteolysis: sequence homologs suggest an ancient signaling cascade. Protein Sci 15 : 84 93.
    • (2006) Protein Sci , vol.15 , pp. 84-93
    • Kinch, L.N.1    Ginalski, K.2    Grishin, N.V.3
  • 22
    • 0036324753 scopus 로고    scopus 로고
    • An algorithm for finding protein-DNA binding sites with applications to chromatin-immunoprecipitation microarray experiments
    • Liu, X.S., Brutlag, D.L. Liu, J.S. (2002) An algorithm for finding protein-DNA binding sites with applications to chromatin-immunoprecipitation microarray experiments. Nat Biotechnol 20 : 835 839.
    • (2002) Nat Biotechnol , vol.20 , pp. 835-839
    • Liu, X.S.1    Brutlag, D.L.2    Liu, J.S.3
  • 23
    • 22944444899 scopus 로고    scopus 로고
    • Regulation of Mycobacterium tuberculosis cell envelope composition and virulence by intramembrane proteolysis
    • Makinoshima, H. Glickman, M.S. (2005) Regulation of Mycobacterium tuberculosis cell envelope composition and virulence by intramembrane proteolysis. Nature 436 : 406 409.
    • (2005) Nature , vol.436 , pp. 406-409
    • Makinoshima, H.1    Glickman, M.S.2
  • 24
    • 33746411866 scopus 로고    scopus 로고
    • Site-2 proteases in prokaryotes: Regulated intramembrane proteolysis expands to microbial pathogenesis
    • Makinoshima, H. Glickman, M.S. (2006) Site-2 proteases in prokaryotes: regulated intramembrane proteolysis expands to microbial pathogenesis. Microbes infect 8 : 1882 1888.
    • (2006) Microbes Infect , vol.8 , pp. 1882-1888
    • Makinoshima, H.1    Glickman, M.S.2
  • 25
    • 23944483538 scopus 로고    scopus 로고
    • Both Corynebacterium diphtheriae DtxR(E175K) and Mycobacterium tuberculosis IdeR(D177K) are dominant positive repressors of IdeR-regulated genes in M. tuberculosis
    • Manabe, Y.C., Hatem, C.L., Kesavan, A.K., Durack, J. Murphy, J.R. (2005) Both Corynebacterium diphtheriae DtxR(E175K) and Mycobacterium tuberculosis IdeR(D177K) are dominant positive repressors of IdeR-regulated genes in M. tuberculosis. Infect Immun 73 : 5988 5994.
    • (2005) Infect Immun , vol.73 , pp. 5988-5994
    • Manabe, Y.C.1    Hatem, C.L.2    Kesavan, A.K.3    Durack, J.4    Murphy, J.R.5
  • 26
    • 0034976601 scopus 로고    scopus 로고
    • Mapping of Mycobacterium tuberculosis katG promoters and their differential expression in infected macrophages
    • Master, S., Zahrt, T.C., Song, J. Deretic, V. (2001) Mapping of Mycobacterium tuberculosis katG promoters and their differential expression in infected macrophages. J Bacteriol 183 : 4033 4039.
    • (2001) J Bacteriol , vol.183 , pp. 4033-4039
    • Master, S.1    Zahrt, T.C.2    Song, J.3    Deretic, V.4
  • 27
    • 0035164513 scopus 로고    scopus 로고
    • Transcriptional regulation of furA and katG upon oxidative stress in Mycobacterium smegmatis
    • Milano, A., Forti, F., Sala, C., Riccardi, G. Ghisotti, D. (2001) Transcriptional regulation of furA and katG upon oxidative stress in Mycobacterium smegmatis. J Bacteriol 183 : 6801 6806.
    • (2001) J Bacteriol , vol.183 , pp. 6801-6806
    • Milano, A.1    Forti, F.2    Sala, C.3    Riccardi, G.4    Ghisotti, D.5
  • 28
    • 2942538880 scopus 로고    scopus 로고
    • Role of KatG catalase-peroxidase in mycobacterial pathogenesis: Countering the phagocyte oxidative burst
    • Ng, V.H., Cox, J.S., Sousa, A.O., MacMicking, J.D. McKinney, J.D. (2004) Role of KatG catalase-peroxidase in mycobacterial pathogenesis: countering the phagocyte oxidative burst. Mol Microbiol 52 : 1291 1302.
    • (2004) Mol Microbiol , vol.52 , pp. 1291-1302
    • Ng, V.H.1    Cox, J.S.2    Sousa, A.O.3    MacMicking, J.D.4    McKinney, J.D.5
  • 29
    • 0035013527 scopus 로고    scopus 로고
    • Regulation of catalase-peroxidase (KatG) expression, isoniazid sensitivity and virulence by furA of Mycobacterium tuberculosis
    • Pym, A.S., Domenech, P., Honore, N., Song, J., Deretic, V. Cole, S.T. (2001) Regulation of catalase-peroxidase (KatG) expression, isoniazid sensitivity and virulence by furA of Mycobacterium tuberculosis. Mol Microbiol 40 : 879 889.
    • (2001) Mol Microbiol , vol.40 , pp. 879-889
    • Pym, A.S.1    Domenech, P.2    Honore, N.3    Song, J.4    Deretic, V.5    Cole, S.T.6
  • 30
    • 33845382268 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis SigM positively regulates Esx secreted protein and non-ribosomal peptide synthesis genes and down regulates virulence-associated surface lipid synthesis
    • Raman, S., Puyang, X., Cheng, T.Y., Young, D.C., Moody, D.B. Husson, R.N. (2006) Mycobacterium tuberculosis SigM positively regulates Esx secreted protein and non-ribosomal peptide synthesis genes and down regulates virulence-associated surface lipid synthesis. J Bacteriol 188 : 8460 8468.
    • (2006) J Bacteriol , vol.188 , pp. 8460-8468
    • Raman, S.1    Puyang, X.2    Cheng, T.Y.3    Young, D.C.4    Moody, D.B.5    Husson, R.N.6
  • 31
    • 33947415761 scopus 로고    scopus 로고
    • Identification of mycobacterial sigma factor binding sites by chromatin immunoprecipitation assays
    • Rodrigue, S., Brodeur, J., Jacques, P.E., Gervais, A.L., Brzezinski, R. Gaudreau, L. (2007) Identification of mycobacterial sigma factor binding sites by chromatin immunoprecipitation assays. J Bacteriol 189 : 1505 1513.
    • (2007) J Bacteriol , vol.189 , pp. 1505-1513
    • Rodrigue, S.1    Brodeur, J.2    Jacques, P.E.3    Gervais, A.L.4    Brzezinski, R.5    Gaudreau, L.6
  • 32
    • 0037344575 scopus 로고    scopus 로고
    • Mechanisms of iron regulation in mycobacteria: Role in physiology and virulence
    • Rodriguez, G.M. Smith, I. (2003) Mechanisms of iron regulation in mycobacteria: role in physiology and virulence. Mol Microbiol 47 : 1485 1494.
    • (2003) Mol Microbiol , vol.47 , pp. 1485-1494
    • Rodriguez, G.M.1    Smith, I.2
  • 33
    • 0036081140 scopus 로고    scopus 로고
    • IdeR, An essential gene in Mycobacterium tuberculosis: Role of IdeR in iron-dependent gene expression, iron metabolism, and oxidative stress response
    • Rodriguez, G.M., Voskuil, M.I., Gold, B., Schoolnik, G.K. Smith, I. (2002) ideR, An essential gene in Mycobacterium tuberculosis: role of IdeR in iron-dependent gene expression, iron metabolism, and oxidative stress response. Infect Immun 70 : 3371 3381.
    • (2002) Infect Immun , vol.70 , pp. 3371-3381
    • Rodriguez, G.M.1    Voskuil, M.I.2    Gold, B.3    Schoolnik, G.K.4    Smith, I.5
  • 34
    • 33750695632 scopus 로고    scopus 로고
    • Mutations in Mycobacterium tuberculosis Rv0444c, the gene encoding anti-SigK, explain high level expression of MPB70 and MPB83 in Mycobacterium bovis
    • Said-Salim, B., Mostowy, S., Kristof, A.S. Behr, M.A. (2006) Mutations in Mycobacterium tuberculosis Rv0444c, the gene encoding anti-SigK, explain high level expression of MPB70 and MPB83 in Mycobacterium bovis. Mol Microbiol 62 : 1251 1263.
    • (2006) Mol Microbiol , vol.62 , pp. 1251-1263
    • Said-Salim, B.1    Mostowy, S.2    Kristof, A.S.3    Behr, M.A.4
  • 36
    • 42949102589 scopus 로고    scopus 로고
    • The katG mRNA of Mycobacterium tuberculosis and Mycobacterium smegmatis is processed at its 5′ end and is stabilized by both a polypurine sequence and translation initiation
    • Sala, C., Forti, F., Magnoni, F. Ghisotti, D. (2008) The katG mRNA of Mycobacterium tuberculosis and Mycobacterium smegmatis is processed at its 5′ end and is stabilized by both a polypurine sequence and translation initiation. BMC Mol Biol 9 : 33.
    • (2008) BMC Mol Biol , vol.9 , pp. 33
    • Sala, C.1    Forti, F.2    Magnoni, F.3    Ghisotti, D.4
  • 37
    • 0043142536 scopus 로고    scopus 로고
    • Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: Insights into the phagosomal environment
    • Schnappinger, D., Ehrt, S., Voskuil, M.I., Liu, Y., Mangan, J.A., Monahan, I.M., et al. (2003) Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: insights into the phagosomal environment. J Exp Med 198 : 693 704.
    • (2003) J Exp Med , vol.198 , pp. 693-704
    • Schnappinger, D.1    Ehrt, S.2    Voskuil, M.I.3    Liu, Y.4    Mangan, J.A.5    Monahan, I.M.6
  • 38
    • 3142683280 scopus 로고    scopus 로고
    • The Bacillus subtilis sigmaW anti-sigma factor RsiW is degraded by intramembrane proteolysis through YluC
    • Schobel, S., Zellmeier, S., Schumann, W. Wiegert, T. (2004) The Bacillus subtilis sigmaW anti-sigma factor RsiW is degraded by intramembrane proteolysis through YluC. Mol Microbiol 52 : 1091 1105.
    • (2004) Mol Microbiol , vol.52 , pp. 1091-1105
    • Schobel, S.1    Zellmeier, S.2    Schumann, W.3    Wiegert, T.4
  • 39
    • 67649660560 scopus 로고    scopus 로고
    • CarD is an essential regulator of rRNA transcription required for Mycobacterium tuberculosis persistence
    • Stallings, C.L., Stephanou, N.C., Chu, L., Hochschild, A., Nickels, B.E. Glickman, M.S. (2009) CarD is an essential regulator of rRNA transcription required for Mycobacterium tuberculosis persistence. Cell 138 : 146 159.
    • (2009) Cell , vol.138 , pp. 146-159
    • Stallings, C.L.1    Stephanou, N.C.2    Chu, L.3    Hochschild, A.4    Nickels, B.E.5    Glickman, M.S.6
  • 40
    • 67349117281 scopus 로고    scopus 로고
    • Making the cut: Central roles of intramembrane proteolysis in pathogenic microorganisms
    • Urban, S. (2009) Making the cut: central roles of intramembrane proteolysis in pathogenic microorganisms. Nat Rev Microbiol 7 : 411 423.
    • (2009) Nat Rev Microbiol , vol.7 , pp. 411-423
    • Urban, S.1
  • 41
    • 0034515724 scopus 로고    scopus 로고
    • ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs
    • Ye, J., Rawson, R.B., Komuro, R., Chen, X., Dave, U.P., Prywes, R., et al. (2000) ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Mol Cell 6 : 1355 1364.
    • (2000) Mol Cell , vol.6 , pp. 1355-1364
    • Ye, J.1    Rawson, R.B.2    Komuro, R.3    Chen, X.4    Dave, U.P.5    Prywes, R.6
  • 42
    • 0035100597 scopus 로고    scopus 로고
    • Mycobacterial FurA is a negative regulator of catalase-peroxidase gene katG
    • Zahrt, T.C., Song, J., Siple, J. Deretic, V. (2001) Mycobacterial FurA is a negative regulator of catalase-peroxidase gene katG. Mol Microbiol 39 : 1174 1185.
    • (2001) Mol Microbiol , vol.39 , pp. 1174-1185
    • Zahrt, T.C.1    Song, J.2    Siple, J.3    Deretic, V.4
  • 43
    • 32044453080 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response
    • Zhang, K., Shen, X., Wu, J., Sakaki, K., Saunders, T., Rutkowski, D.T., et al. (2006) Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response. Cell 124 : 587 599.
    • (2006) Cell , vol.124 , pp. 587-599
    • Zhang, K.1    Shen, X.2    Wu, J.3    Sakaki, K.4    Saunders, T.5    Rutkowski, D.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.