Discriminative auditory fear learning requires both tuned and nontuned auditory pathways to the amygdala

Journal of Neuroscience

Volumn 30, Issue 29, 2010, Pages 9782-9787

  Antunes, Raquel ^a   Moita, Marta A ^a  

^a INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUDITORY CORTEX; CONTROLLED STUDY; DISCRIMINATION LEARNING; FEAR; INSTRUMENTAL CONDITIONING; MALE; MEDIAL GENICULATE BODY; NERVE CELL NETWORK; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ACOUSTIC STIMULATION; AMYGDALA; ANIMALS; AUDITORY PATHWAYS; CONDITIONING (PSYCHOLOGY); CONDITIONING, CLASSICAL; DISCRIMINATION LEARNING; EXTINCTION, PSYCHOLOGICAL; FEAR; GENICULATE BODIES; MALE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 77954836787     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1037-10.2010     Document Type: Article

References (32)

1. Amano T, Unal CT, Paré D (2010) Synaptic correlates of fear extinction in the amygdala. Nat Neurosci 13:489-494.
2. Armony JL, Servan-Schreiber D, Romanski LM, Cohen JD, LeDoux JE (1997) Stimulus generalization of fear responses: effects of auditory cortex lesions in a computational model and in rats. Cereb Cortex 7:157-165. (Pubitemid 27120277)
3. Bang SJ, Allen TA, Jones LK, Boguszewski P, Brown TH (2008) Asymmetrical stimulus generalization following differential fear conditioning. Neurobiol Learn Mem 90:200-216.
4. Boatman JA, Kim JJ (2006) A thalamo-cortico-amygdala pathway mediates auditory fear conditioning in the intact brain. Eur J Neurosci 24:894-900.
5. Bordi F, LeDoux JE (1994a) Response properties of single units in areas of rat auditory thalamus that project to the amygdala. I. Acoustic discharge patterns and frequency receptive fields. Exp Brain Res 98:261-274.
6. Bordi F, LeDoux JE (1994b) Response properties of single units in areas of rat auditory thalamus that project to the amygdala. II. Cells receiving convergent auditory and somatosensory inputs and cells antidromically activated by amygdala stimulation. Exp Brain Res 98:275-286.
7. Duvarci S, Bauer EP, Paré D (2009) The bed nucleus of the stria terminalis mediates interindividual variations in anxiety and fear. J Neurosci 29: 10357-10361.
8. Ehrlich I, Humeau Y, Grenier F, Ciocchi S, Herry C, Lüthi A (2009) Amygdala inhibitory circuits and the control of fear memory. Neuron 62:757-771.
9. Gao E, Suga N (2000) Experience-dependent plasticity in the auditory cortex and the inferior colliculus of bats: role of the corticofugal system. Proc Natl Acad Sci U S A 97:8081-8086.
10. Grillon C (2002) Startle reactivity and anxiety disorders: aversive conditioning, context, and neurobiology. Biol Psychiatry 52:958-975.
11. Han JH, Kushner SA, Yiu AP, Cole CJ, Matynia A, Brown RA, Neve RL, Guzowski JF, Silva AJ, Josselyn SA (2007) Neuronal competition and selection during memory formation. Science 316:457-460.
12. Han JH, Yiu AP, Cole CJ, Hsiang HL, Neve RL, Josselyn SA (2008) Increasing CREB in the auditory thalamus enhances memory and generalization of auditory conditioned fear. Learn Mem 15:443-453.
13. Jarrell TW, Gentile CG, McCabe PM, Schneiderman N (1986) The role of the medial geniculate region in differential Pavlovian conditioning of bradycardia in rabbits. Brain Res 374:126-136. (Pubitemid 16078106)
14. Jarrell TW, Gentile CG, Romanski LM, McCabe PM, Schneiderman N (1987) Involvement of cortical and thalamic auditory regions in retention of differential bradycardiac conditioning to acoustic conditioned stimuli in rabbits. Brain Res 412:285-294.
15. Kimura A, Donishi T, Sakoda T, Hazama M, Tamai Y (2003) Auditory thalamic nuclei projections to the temporal cortex in the rat. Neuroscience 117:1003-1016.
16. LeDoux JE (2000) Emotion circuits in the brain. Annu Rev Neurosci 23:155-184.
17. LeDoux JE, Sakaguchi A, Reis DJ (1983) Subcortical efferent projections of the medial geniculate nucleus mediat e emotional responses conditioned to acoustic stimuli. J Neurosci 4:683-698.
18. Ma X, Suga N (2009) Specific and nonspecific plasticity of the primary auditory cortex elicited by thalamic auditory neurons. J Neurosci 29:4888-4896.
19. McCabe PM, McEchron MD, Green EJ, Schneiderman N (1993) Electrolytic and ibotenic acid lesions of the medial subnucleus of the medial geniculate prevent the acquisition of classically conditioned heart rate to a single acoustic stimulus in rabbits. Brain Res 619:291-298.
20. McKernan MG, Shinnick-Gallagher P (1997) Fear conditioning induces a lasting potentiation of synaptic currents in vitro. Nature 390:607-611.
21. Orsini CA, Maren S (2009) Glutamate receptors in the medial geniculate nucleus are necessary for expression and extinction of conditioned fear in rats. Neurobiol Learn Mem 92:581-589.
22. Pan BX, Dong Y, Ito W, Yanagawa Y, Shigemoto R, Morozov A (2009) Selective gating of glutamatergic inputs to excitatory neurons of amygdala by presynaptic GABAb receptor. Neuron 61:917-929.
23. Paxinos G, Watson C (1986) The rat brain in stereotaxic coordinates. Sydney: Academic.
24. Pearce JM (1994) Discrimination and categorization. In: Animal learning and cognition, Ed 2 (Mackintosh NJ, ed), pp 109-134. San Diego: Academic.
25. Romanski LM, LeDoux JE (1992) Equipotentiality of thalamo-amygdala and thalamo-cortico-amygdala circuits in auditory fear conditioning. J Neurosci 12:4501-4509.
26. Romanski LM, LeDoux JE (1993) Information cascade from primary auditory cortex to the amygdala: corticocortical and corticoamygdaloid projections of temporal cortex in the rat. Cereb Cortex 3:515-532. (Pubitemid 24017344)
27. Rumpel S, LeDoux J, Zador A, Malinow R (2005) Postsynaptic receptor trafficking underlying a form of associative learning. Science 308:83-88.
28. Rutkowski RG, Weinberger NM (2005) Encoding of learned importance of sound by magnitude of representational area in primary auditory cortex. Proc Natl Acad Sci U S A 102:13664-13669.
29. Shaban H, Humeau Y, Herry C, Cassasus G, Shigemoto R, Ciocchi S, Barbieri S, van der Putten H, Kaupmann K, Bettler B, Lüthi A (2006) Generalization of amygdala LTP and conditioned fear in the absence of presynaptic inhibition. Nat Neurosci 9:1028-1035.
30. Shin RM, Tsvetkov E, Bolshakov VY (2006) Spatiotemporal asymmetry of associative synaptic plasticity in fear conditioning pathways. Neuron 52:883-896.
31. Teich AH, McCabe PM, Gentile CG, Jarrell TW, Winters RW, Liskowsky DR, Schneiderman N (1988) Role of auditory cortex in the acquisition of differential heart rate conditioning. Physiol Behav 44:405-412.
32. Weinberger NM (2007) Associative representational plasticity in the auditory cortex: a synthesis of two disciplines. Learn Mem 14:1-16.