Synthesis and cloxacillin antimicrobial enhancement of 2-methylsulfonylimidazolyl-1,4-dihydropyridine derivatives

Daru

Volumn 18, Issue 2, 2010, Pages 118-123

  Akbarzadeh, T ^a   Fallah Tafti, A ^a   Samadi, N ^a   Foroumadi, A ^b   Amanlou, M ^a   Faramarzi, M A ^c   Shafiee, A ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Cloxacillin; Dihydropyridines; Multidrug resistant staphylococcus aureus

Indexed keywords

1,4 DIHYDROPYRIDINE DERIVATIVE; 2 METHYLSULFONYLIMIDAZOLYL 1,4 DIHYDROPYRIDINE DERIVATIVE; CLOXACILLIN; UNCLASSIFIED DRUG;

AGAR DIFFUSION; ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISK DIFFUSION; DRUG POTENTIATION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN;

EID: 77954832332     PISSN: 15608115     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Carleton HA, Diep BA, Charlebois ED, Sensabaugh GF, Perdreau-Remington F. Community-adapted methicillin-resistant Staphylococcus aureus (MRSA): population dynamics of an expanding community reservoir of MRSA. J. Infect. Dis, 2004; 190: 1730-1738.
2. Khairulddin N, Bishop L, Lamagni TL, Sharland M, Duckworth G. Emergence of methicillin resistant Staphylococcus aureus (MRSA) bacteraemia among children in England and Wales, 1990-2001. Arch. Dis. Child, 2004; 89: 378-379.
3. Hollis RJ, Barr JL, Doebbeling BN, Pfaller MA, Wenzel RP. Familial Carriage of methicillin-resistant Staphylococcus aureus and subsequent infection in a premature neonate. Clin. Infect. Dis, 1995; 21: 328-332.
4. Viveiros M, Amaral L. Enhancement of antibiotic activityagainst poly-drug resistant Mycobacterium tuberculosis by phenothiazines. Int. J. Antimicrob. Agents 2001, 17:225-228.
5. + efflux pumps of the bacterium and the killing macrophage. Anti-Infective Agents Med. Chem, 2008; 7: 63-72.
6. Amaral L, Martins M, Viveiros M. Enhanced killing of intracellular multidrug resistant Mycobacterium tuberculosis by compounds that affect the activity of efflux pumps. J. Antimicrob. Chemother, 2007; 59: 1237-1246.
7. Fisher GA, Sikic BI, Drug resistance in clinical oncology and hematology, Introduction. Hematol. Oncol. Clin. North Am, 1995; 9 (2): xi-xii.
8. Shafiee A, Rastkari N, Sharifzadeh M. Anticonvulsant activities of new 1,4-dihydropyridine derivatives containing 4-nitroimidazolyl substituents, Daru 2004; 12: 81-86.
9. Miri R, Niknahad H, Vazin A, Azarpira A, Shafiei A. Synthesis and smooth muscle calcium channel antagonist effects of new derivatives of 1,4-dihydropyridine containing nitroimidazol substituent, DARU 2002; 10: 130-136.
10. Lak P, Amini M, Safavi M, Shafiee A, Shahverdi AR. Enhancement of the antibacterial activity of ciprofloxacin against Staphylococcus aureus by 3-alkyl ester and 3-aryl ester of hexahydroqunoline derivatives. Arzneim-Forsch/Drug Res, 2008; 58: 464-468.
11. Clemens RJ, Hyatt JA, Acetoacetylation with 2,2,6-trimethyl-4H-1,3-dioxin-4-one: a convenient alternative to diketen. J. Org. Chem, 1985; 50: 2431-2433.
12. Shafiee A, Dehpour AR, Hadizadeh F, Azimi M. Syntheses and calcium channel antagonist activity of nifedipine analogues with methylsulfonylimidazolyl substituent. Pharm. Acta Helv, 1998; 73: 75-79.
13. Inayama S, Mori T, Tanami T, Amano T, Soda K. 5-(Imidazol-5-ylmethylene)-2,2-dimethyl-1,3-dioxane4,6-dione derivatives. Jpn. Kokai Tokkyo Koho JP 6212, 763 1987. Chem. Abstr, 1987, 106, 156477d.
14. th ed. NCCLS document M7-A7. Wayne, PA, 2006.
15. Basu LR, Mazumdar K, Dutta NK, Karak P, Dastidar SG. Antibacterial property of the antipsychotic agent prochlorperazine, and its synergism with methdilazine, Microb. Res, 2005; 160: 95-100.