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Volumn 28, Issue 7, 2010, Pages 1260-1269

Dicer ablation impairs prostate stem cell activity and causes prostate atrophy

Author keywords

Dicer; MicroRNAs; Prostate spheres; Prostate stem cells

Indexed keywords

ALPHA6 INTEGRIN; CD31 ANTIGEN; CD45 ANTIGEN; DICER; MICRORNA;

EID: 77954820848     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.455     Document Type: Article
Times cited : (19)

References (49)
  • 1
    • 53549101290 scopus 로고    scopus 로고
    • The evolution of our thinking about microRNAs
    • Ambros V. The evolution of our thinking about microRNAs. Nat Med 2008;14:1036-1040.
    • (2008) Nat Med , vol.14 , pp. 1036-1040
    • Ambros, V.1
  • 2
    • 53549133101 scopus 로고    scopus 로고
    • The perfect storm of tiny RNAs
    • Ruvkun G. The perfect storm of tiny RNAs. Nat Med 2008;14:1041-1045.
    • (2008) Nat Med , vol.14 , pp. 1041-1045
    • Ruvkun, G.1
  • 3
    • 39749110083 scopus 로고    scopus 로고
    • Small non-coding RNAs in animal development
    • Stefani G, Slack FJ. Small non-coding RNAs in animal development. Nat Rev Mol Cell Biol 2008;9:219-230.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 219-230
    • Stefani, G.1    Slack, F.J.2
  • 4
    • 54349104464 scopus 로고    scopus 로고
    • Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicerdependent Small RNAs
    • Babiarz JE, Ruby JG, Wang Y et al. Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicerdependent Small RNAs. Genes Dev 2008;22:2773-2785.
    • (2008) Genes Dev , vol.22 , pp. 2773-2785
    • Babiarz, J.E.1    Ruby, J.G.2    Wang, Y.3
  • 5
    • 23344439006 scopus 로고    scopus 로고
    • The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb
    • Harfe BD, McManus MT, Mansfield JH et al. The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. Proc Natl Acad Sci USA 2005;102:10898-10903.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 10898-10903
    • Harfe, B.D.1    McManus, M.T.2    Mansfield, J.H.3
  • 6
    • 33847323881 scopus 로고    scopus 로고
    • DGCR8 is essential for micro-RNA biogenesis and silencing of embryonic stem cell self-renewal
    • Wang Y, Medvid R, Melton C et al. DGCR8 is essential for micro-RNA biogenesis and silencing of embryonic stem cell self-renewal. Nat Genet 2007;39:380-385.
    • (2007) Nat Genet , vol.39 , pp. 380-385
    • Wang, Y.1    Medvid, R.2    Melton, C.3
  • 7
    • 13844294261 scopus 로고    scopus 로고
    • Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing
    • Kanellopoulou C, Muljo SA, Kung AL et al. Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev 2005;19:489-501.
    • (2005) Genes Dev , vol.19 , pp. 489-501
    • Kanellopoulou, C.1    Muljo, S.A.2    Kung, A.L.3
  • 8
    • 33644619021 scopus 로고    scopus 로고
    • Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs
    • Yi R, O'Carroll D, Pasolli HA et al. Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs. Nat Genet 2006;38:356-362.
    • (2006) Nat Genet , vol.38 , pp. 356-362
    • Yi, R.1    O'Carroll, D.2    Pasolli, H.A.3
  • 9
    • 33646716847 scopus 로고    scopus 로고
    • The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles
    • Andl T, Murchison EP, Liu F et al. The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles. Curr Biol 2006;16:1041-1049.
    • (2006) Curr Biol , vol.16 , pp. 1041-1049
    • Andl, T.1    Murchison, E.P.2    Liu, F.3
  • 10
    • 46249107572 scopus 로고    scopus 로고
    • Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells
    • Mudhasani R, Zhu Z, Hutvagner G et al. Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells. J Cell Biol 2008;181:1055-1063.
    • (2008) J Cell Biol , vol.181 , pp. 1055-1063
    • Mudhasani, R.1    Zhu, Z.2    Hutvagner, G.3
  • 11
    • 63349107736 scopus 로고    scopus 로고
    • Residual microRNA expression dictates the extent of inner ear development in conditional Dicer knockout mice
    • Soukup GA, Fritzsch B, Pierce ML et al. Residual microRNA expression dictates the extent of inner ear development in conditional Dicer knockout mice. Dev Biol 2009;328:328-341.
    • (2009) Dev Biol , vol.328 , pp. 328-341
    • Soukup, G.A.1    Fritzsch, B.2    Pierce, M.L.3
  • 12
    • 33144457798 scopus 로고    scopus 로고
    • Dicer function is essential for lung epithelium morphogenesis
    • Harris KS, Zhang Z, McManus MT et al. Dicer function is essential for lung epithelium morphogenesis. Proc Natl Acad Sci USA 2006;103:2208-2213.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2208-2213
    • Harris, K.S.1    Zhang, Z.2    McManus, M.T.3
  • 13
    • 36248978699 scopus 로고    scopus 로고
    • MicroRNA expression is required for pancreatic islet cell genesis in the mouse
    • Lynn FC, Skewes-Cox P, Kosaka Y et al. MicroRNA expression is required for pancreatic islet cell genesis in the mouse. Diabetes 2007;56:2938-2945.
    • (2007) Diabetes , vol.56 , pp. 2938-2945
    • Lynn, F.C.1    Skewes-Cox, P.2    Kosaka, Y.3
  • 14
    • 55749112141 scopus 로고    scopus 로고
    • Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis
    • Shi S, Yu L, Chiu C et al. Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis. J Am Soc Nephrol 2008;19:2159-2169.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 2159-2169
    • Shi, S.1    Yu, L.2    Chiu, C.3
  • 15
    • 55749103053 scopus 로고    scopus 로고
    • Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease
    • Harvey SJ, Jarad G, Cunningham J et al. Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease. J Am Soc Nephrol 2008;19:2150-2158.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 2150-2158
    • Harvey, S.J.1    Jarad, G.2    Cunningham, J.3
  • 16
    • 55749104549 scopus 로고    scopus 로고
    • Podocyte-specific loss of functional microRNAs leads to rapid glomerular and tubular injury
    • Ho J, Ng KH, Rosen S et al. Podocyte-specific loss of functional microRNAs leads to rapid glomerular and tubular injury. J Am Soc Nephrol 2008;19:2069-2075.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 2069-2075
    • Ho, J.1    Ng, K.H.2    Rosen, S.3
  • 17
    • 62749161460 scopus 로고    scopus 로고
    • Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract
    • Pastorelli LM, Wells S, Fray M et al. Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract. Mamm Genome 2009;20:140-151.
    • (2009) Mamm Genome , vol.20 , pp. 140-151
    • Pastorelli, L.M.1    Wells, S.2    Fray, M.3
  • 18
    • 59749089928 scopus 로고    scopus 로고
    • miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex
    • De Pietri Tonelli D, Pulvers JN, Haffner C et al. miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex. Development 2008;135:3911-3921.
    • (2008) Development , vol.135 , pp. 3911-3921
    • De Pietri Tonelli, D.1    Pulvers, J.N.2    Haffner, C.3
  • 19
    • 44449132518 scopus 로고    scopus 로고
    • Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration
    • Cuellar TL, Davis TH, Nelson PT et al. Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration. Proc Natl Acad Sci USA 2008;105:5614-5619.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 5614-5619
    • Cuellar, T.L.1    Davis, T.H.2    Nelson, P.T.3
  • 20
    • 51049110261 scopus 로고    scopus 로고
    • Dicer-dependent microRNA pathway safeguards regulatory T cell function
    • Liston A, Lu LF, O'Carroll D et al. Dicer-dependent microRNA pathway safeguards regulatory T cell function. J Exp Med 2008;205:1993-2004.
    • (2008) J Exp Med , vol.205 , pp. 1993-2004
    • Liston, A.1    Lu, L.F.2    O'Carroll, D.3
  • 21
    • 52949090784 scopus 로고    scopus 로고
    • Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis
    • Suarez Y, Fernandez-Hernando C, Yu J et al. Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis. Proc Natl Acad Sci USA 2008;105:14082-14087.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14082-14087
    • Suarez, Y.1    Fernandez-Hernando, C.2    Yu, J.3
  • 22
    • 42949179661 scopus 로고    scopus 로고
    • Impaired microRNA processing causes corpus luteum insufficiency and infertility in mice
    • Otsuka M, Zheng M, Hayashi M et al. Impaired microRNA processing causes corpus luteum insufficiency and infertility in mice. J Clin Invest 2008;118:1944-54.
    • (2008) J Clin Invest , vol.118 , pp. 1944-1954
    • Otsuka, M.1    Zheng, M.2    Hayashi, M.3
  • 23
    • 58849154000 scopus 로고    scopus 로고
    • Sertoli cell Dicer is essential for spermatogenesis in mice
    • Papaioannou MD, Pitetti JL, Ro S et al. Sertoli cell Dicer is essential for spermatogenesis in mice. Dev Biol 2009;326:250-259.
    • (2009) Dev Biol , vol.326 , pp. 250-259
    • Papaioannou, M.D.1    Pitetti, J.L.2    Ro, S.3
  • 24
    • 0034307013 scopus 로고    scopus 로고
    • Molecular genetics of prostate cancer
    • Abate-Shen C, Shen MM. Molecular genetics of prostate cancer. Genes Dev 2000;14:2410-2434.
    • (2000) Genes Dev , vol.14 , pp. 2410-2434
    • Abate-Shen, C.1    Shen, M.M.2
  • 26
    • 18744377702 scopus 로고    scopus 로고
    • The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis
    • Xin L, Lawson DA, Witte ON. The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis. Proc Natl Acad Sci USA 2005;102:6942-6947.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 6942-6947
    • Xin, L.1    Lawson, D.A.2    Witte, O.N.3
  • 27
    • 70349438989 scopus 로고    scopus 로고
    • A luminal epithelial stem cell that is a cell of origin for prostate cancer
    • Wang X, Kruithof-de Julio M, Economides KD et al. A luminal epithelial stem cell that is a cell of origin for prostate cancer. Nature 2009;461:495-500.
    • (2009) Nature , vol.461 , pp. 495-500
    • Wang, X.1    Kruithof-De Julio, M.2    Economides, K.D.3
  • 28
    • 75649083146 scopus 로고    scopus 로고
    • Low-density Taqman miRNA array reveals miRNAs differentially expressed in prostatic stem cells and luminal cells
    • Zhang L, Zhao W, Valdez JM, et al. Low-density Taqman miRNA array reveals miRNAs differentially expressed in prostatic stem cells and luminal cells. Prostate 2009;70:297-304.
    • (2009) Prostate , vol.70 , pp. 297-304
    • Zhang, L.1    Zhao, W.2    Valdez, J.M.3
  • 29
    • 0034520311 scopus 로고    scopus 로고
    • A small composite probasin promoter confers high levels of prostate-specific gene expression through regulation by androgens and glucocorticoids in vitro and in vivo
    • Zhang J, Thomas TZ, Kasper S et al. A small composite probasin promoter confers high levels of prostate-specific gene expression through regulation by androgens and glucocorticoids in vitro and in vivo. Endocrinology 2000;141:4698-4710.
    • (2000) Endocrinology , vol.141 , pp. 4698-4710
    • Zhang, J.1    Thomas, T.Z.2    Kasper, S.3
  • 30
    • 0141564629 scopus 로고    scopus 로고
    • Transgenic mouse with high Cre recombinase activity in all prostate lobes, seminal vesicle, and ductus deferens
    • Jin C, McKeehan K, Wang F. Transgenic mouse with high Cre recombinase activity in all prostate lobes, seminal vesicle, and ductus deferens. Prostate 2003;57:160-164.
    • (2003) Prostate , vol.57 , pp. 160-164
    • Jin, C.1    McKeehan, K.2    Wang, F.3
  • 31
    • 72249113369 scopus 로고    scopus 로고
    • Lin-Sca-1+CD49fhigh stem/progenitors are tumor-initiating cells in the Pten-null prostate cancer model
    • Mulholland DJ, Xin L, Morim A et al. Lin-Sca-1+CD49fhigh stem/progenitors are tumor-initiating cells in the Pten-null prostate cancer model. Cancer Res 2009;69:8555-8562.
    • (2009) Cancer Res , vol.69 , pp. 8555-8562
    • Mulholland, D.J.1    Xin, L.2    Morim, A.3
  • 32
    • 33646739524 scopus 로고    scopus 로고
    • Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor
    • Xin L, Teitell MA, Lawson DA et al. Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor. Proc Natl Acad Sci USA 2006;103:7789-7794.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 7789-7794
    • Xin, L.1    Teitell, M.A.2    Lawson, D.A.3
  • 33
    • 0141483063 scopus 로고    scopus 로고
    • In vivo regeneration of murine prostate from dissociated cell populations of postnatal epithelia and urogenital sinus mesenchyme
    • Xin L, Ide H, Kim Y et al. In vivo regeneration of murine prostate from dissociated cell populations of postnatal epithelia and urogenital sinus mesenchyme. Proc Natl Acad Sci USA 2003;100 (Suppl 1): 11896-11903.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.SUPPL. 1 , pp. 11896-11903
    • Xin, L.1    Ide, H.2    Kim, Y.3
  • 34
    • 36249006969 scopus 로고    scopus 로고
    • Self-renewal and multilineage differentiation in vitro from murine prostate stem cells
    • DOI 10.1634/stemcells.2007-0355
    • Xin L, Lukacs RU, Lawson DA et al. Self-renewal and multilineage differentiation in vitro from murine prostate stem cells. Stem Cells 2007;25:2760-2769. (Pubitemid 350127860)
    • (2007) Stem Cells , vol.25 , Issue.11 , pp. 2760-2769
    • Xin, L.1    Lukacs, R.U.2    Lawson, D.A.3    Cheng, D.4    Witte, O.N.5
  • 35
    • 12844274300 scopus 로고    scopus 로고
    • Mutation of the androgen receptor causes oncogenic transformation of the prostate
    • Han G, Buchanan G, Ittmann M et al. Mutation of the androgen receptor causes oncogenic transformation of the prostate. Proc Natl Acad Sci USA 2005;102:1151-1156.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 1151-1156
    • Han, G.1    Buchanan, G.2    Ittmann, M.3
  • 37
    • 34047265189 scopus 로고    scopus 로고
    • Inactivation of Apc in the mouse prostate causes prostate carcinoma
    • Bruxvoort KJ, Charbonneau HM, Giambernardi TA et al. Inactivation of Apc in the mouse prostate causes prostate carcinoma. Cancer Res 2007;67:2490-2496.
    • (2007) Cancer Res , vol.67 , pp. 2490-2496
    • Bruxvoort, K.J.1    Charbonneau, H.M.2    Giambernardi, T.A.3
  • 38
    • 23844459838 scopus 로고    scopus 로고
    • p63 regulates commitment to the prostate cell lineage
    • Signoretti S, Pires MM, Lindauer M et al. p63 regulates commitment to the prostate cell lineage. Proc Natl Acad Sci USA 2005;102:11355-11360.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 11355-11360
    • Signoretti, S.1    Pires, M.M.2    Lindauer, M.3
  • 39
    • 34247511981 scopus 로고    scopus 로고
    • p63 Is Essential for the proliferative potential of stem cells in stratified epithelia
    • Senoo M, Pinto F, Crum CP et al. p63 Is Essential for the proliferative potential of stem cells in stratified epithelia. Cell 2007;129:523-536.
    • (2007) Cell , vol.129 , pp. 523-536
    • Senoo, M.1    Pinto, F.2    Crum, C.P.3
  • 40
    • 39749101294 scopus 로고    scopus 로고
    • Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage
    • Koralov SB, Muljo SA, Galler GR et al. Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage. Cell 2008;132:860-874.
    • (2008) Cell , vol.132 , pp. 860-874
    • Koralov, S.B.1    Muljo, S.A.2    Galler, G.R.3
  • 41
    • 35748958766 scopus 로고    scopus 로고
    • Essential role for Dicer during skeletal muscle development
    • O'Rourke JR, Georges SA, Seay HR et al. Essential role for Dicer during skeletal muscle development. Dev Biol 2007;311:359-368.
    • (2007) Dev Biol , vol.311 , pp. 359-368
    • O'Rourke, J.R.1    Georges, S.A.2    Seay, H.R.3
  • 42
    • 52949113864 scopus 로고    scopus 로고
    • Deletion of Dicer in somatic cells of the female reproductive tract causes sterility
    • Nagaraja AK, Andreu-Vieyra C, Franco HL et al. Deletion of Dicer in somatic cells of the female reproductive tract causes sterility. Mol Endocrinol 2008;22:2336-2352.
    • (2008) Mol Endocrinol , vol.22 , pp. 2336-2352
    • Nagaraja, A.K.1    Andreu-Vieyra, C.2    Franco, H.L.3
  • 43
    • 70350455762 scopus 로고    scopus 로고
    • Dicer is required for proper liver zonation
    • Sekine S, Ogawa R, McManus MT et al. Dicer is required for proper liver zonation. J Pathol 2009;219:365-372.
    • (2009) J Pathol , vol.219 , pp. 365-372
    • Sekine, S.1    Ogawa, R.2    McManus, M.T.3
  • 44
    • 66149120204 scopus 로고    scopus 로고
    • Disruption of Dicer1 induces dysregulated fetal gene expression and promotes hepatocarcinogenesis
    • e1-e4
    • Sekine S, Ogawa R, Ito R et al. Disruption of Dicer1 induces dysregulated fetal gene expression and promotes hepatocarcinogenesis. Gastroenterology 2009;136:2304-2315 e1-e4.
    • (2009) Gastroenterology , vol.136 , pp. 2304-2315
    • Sekine, S.1    Ogawa, R.2    Ito, R.3
  • 45
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP. MicroRNAs: Target recognition and regulatory functions. Cell 2009;136:215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 46
    • 13744254695 scopus 로고    scopus 로고
    • A large-scale analysis of mRNA polyadenylation of human and mouse genes
    • Tian B, Hu J, Zhang H et al. A large-scale analysis of mRNA polyadenylation of human and mouse genes. Nucleic Acids Res 2005;33:201-212.
    • (2005) Nucleic Acids Res , vol.33 , pp. 201-212
    • Tian, B.1    Hu, J.2    Zhang, H.3
  • 47
    • 66049104920 scopus 로고    scopus 로고
    • Progressive lengthening of 3′ untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development
    • Ji Z, Lee JY, Pan Z et al. Progressive lengthening of 3′ untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development. Proc Natl Acad Sci USA 2009;106:7028-7033.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 7028-7033
    • Ji, Z.1    Lee, J.Y.2    Pan, Z.3
  • 48
    • 46249092601 scopus 로고    scopus 로고
    • Proliferating cells express mRNAs with shortened 30 untranslated regions and fewer microRNA target sites
    • Sandberg R, Neilson JR, Sarma A et al. Proliferating cells express mRNAs with shortened 30 untranslated regions and fewer microRNA target sites. Science 2008;320:1643-1647.
    • (2008) Science , vol.320 , pp. 1643-1647
    • Sandberg, R.1    Neilson, J.R.2    Sarma, A.3
  • 49
    • 68749113985 scopus 로고    scopus 로고
    • Widespread shortening of 3′UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
    • Mayr C, Bartel DP. Widespread shortening of 3′UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells. Cell 2009;138:673-684.
    • (2009) Cell , vol.138 , pp. 673-684
    • Mayr, C.1    Bartel, D.P.2


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